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Golden Age of Insecticide Research: Past, Present, or Future?
Abstract
▪ Abstract Insecticide research led to the first “complete” victories in combatting pests almost 50 years ago with the chlorinated hydrocarbons followed quickly by the organophosphates, methylcarbamates, and pyrethroids—all neuroactive chemicals. This Golden Age of Discovery was the source of most of our current insecticides. The challenge then became health and the environment, a Golden Age met with selective and degradable compounds. Next the focus shifted to resistance, novel biochemical targets, and new chemical approaches for pest control. The current Golden Age of Genetic Engineering has curtailed, but is unlikely to eliminate, chemical use on major crops. Insecticide research, having passed through several Golden Ages, is now in a renaissance of integrating chemicals and biologicals for sustainable pest control with human safety.
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Citations
Cited by
Developmental Neurotoxicity of Pyrethroid Insecticides: Critical Review and Future Research Needs
Shafer, T. J., Meyer, D. A., & Crofton, K. M. (2005) · Environmental Health Perspectives · doi:10.1289/ehp.7254 · Cited by 538
Nkya, T. E., Akhouayri, I., Kisinza, W., & David, J.-P. (2013) · Insect Biochemistry and Molecular Biology · doi:10.1016/j.ibmb.2012.10.006 · Cited by 402
Neuroreceptors and Ion Channels as the Basis for Drug Action: Past, Present, and Future
Narahashi, T. (2000) · The Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(24)39034-2 · Cited by 257
Toxicokinetics of lambda-cyhalothrin in rats
Anadón, A., Martínez, M., Martínez, M. A., Díaz, M. J., & Martínez-Larrañaga, M. R. (2006) · Toxicology Letters · doi:10.1016/j.toxlet.2006.01.014 · Cited by 86
Metadata
- Authors
- Casida, J. E., & Quistad, G. B.
- Venue
- Annual Review of Entomology
- Publisher
- Annual Reviews
- Published
- 1998-01
- Volume
- 43
- Issue
- 1
- Pages
- 1-16
- ISSN
- 0066-4170 (ISSN-L)
- 1545-4487
- OpenAlex
- W2123548738
- Cited by
- 666
- References
- 0
- FWCI
- 11.54
- Type
- journal article
- Language
- en
- Open access
- closed
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- Casida, J. E., & Quistad, G. B. (1998). Golden Age of Insecticide Research: Past, Present, or Future? Annual Review of Entomology. https://doi.org/10.1146/annurev.ento.43.1.1
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
