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CONSERVATION GENETICS

Frankham, R.·1995·Annual Review of Genetics

Abstract

Inbreeding depression, accumulation and loss of deleterious mutations, loss of genetic variation in small populations, genetic adaptation to captivity and its effect on reintroduction success, and outbreeding depression are reviewed. The impact of genetic factors in endangerment and extinction has been underestimated in some recent publications. Inbreeding depression in wildlife and in the field has been clearly established, while its impact has been greatly underestimated. The size of populations where genetic factors become important is higher than previously recognized, as Ne/N ratios average 0.11. Purging effects have been overestimated as a mechanism for eliminating deleterious alleles in small populations. The impact of loss of genetic variation in increasing the susceptibility of populations to environmental stochasticity and catastrophes has generally been ignored. Consequently, extinctions are often attributed to "nongenetic" factors when these may have interacted with genetic factors to cause extinction.

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Crossref · 10.1146/annurev.ge.29.120195.001513

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Metadata

Authors
Frankham, R.
Venue
Annual Review of Genetics
Published
1995-12
Volume
29
Issue
1
Pages
305-327
ISSN
  • 0066-4197 (ISSN-L)
  • 1545-2948
OpenAlex
W4246640010
Cited by
1,050
References
0
FWCI
6.49
Type
journal article
Language
en
Open access
closed

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