The DOI matches its Crossref record; 219 of the 219 references it cites were found in a registry or an index.
DNA MISMATCH REPAIR AND GENETIC INSTABILITY
Abstract
▪ Abstract Mismatch repair (MMR) systems play a central role in promoting genetic stability by repairing DNA replication errors, inhibiting recombination between non-identical DNA sequences and participating in responses to DNA damage. The discovery of a link between human cancer and MMR defects has led to an explosion of research on eukaryotic MMR. The key proteins in MMR are highly conserved from bacteria to mammals, and this conservation has been critical for defining the components of eukaryotic MMR systems. In eukaryotes, there are multiple homologs of the key bacterial MutS and MutL MMR proteins, and these homologs form heterodimers that have discrete roles in MMR-related processes. This review describes the genetic and biochemical approaches used to study MMR, and summarizes the diverse roles that MMR proteins play in maintaining genetic stability.
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2 retracted
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RetractedThe Genome Sequence of Drosophila melanogaster
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MISMATCH REPAIR IN REPLICATION FIDELITY, GENETIC RECOMBINATION, AND CANCER BIOLOGY
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Cited by
Genome maintenance mechanisms for preventing cancer
Hoeijmakers, J. H. J. (2001) · Nature · doi:10.1038/35077232 · Cited by 3,939
Regulation of Homologous Recombination in Eukaryotes
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Eukaryotic Mismatch Repair in Relation to DNA Replication
Kunkel, T. A., & Erie, D. A. (2015) · Annual Review of Genetics · doi:10.1146/annurev-genet-112414-054722 · Cited by 432
The emergence of antibiotic resistance by mutation
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Mismatch repair and DNA damage signalling
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Metadata
- Authors
- Harfe, B. D., & Jinks-Robertson, S.
- Venue
- Annual Review of Genetics
- Publisher
- Annual Reviews
- Published
- 2000-12
- Volume
- 34
- Issue
- 1
- Pages
- 359-399
- ISSN
- 0066-4197 (ISSN-L)
- 1545-2948
- OpenAlex
- W2104566573
- Cited by
- 608
- References
- 219
- FWCI
- 2.46
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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