The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
T-Box Genes in Vertebrate Development
Abstract
The myriad developmental roles served by the T-box family of transcription factor genes defy easy categorization. Present in all metazoans, the T-box genes are involved in early embryonic cell fate decisions, regulation of the development of extraembryonic structures, embryonic patterning, and many aspects of organogenesis. They are unusual in displaying dosage sensitivity in most instances. In humans, mutations in T-box genes are responsible for developmental dysmorphic syndromes, and several T-box genes have been implicated in neoplastic processes. T-box transcription factors function in many different signaling pathways, notably bone morphogenetic protein and fibroblast growth factor pathways. The few downstream target genes that have been identified indicate a wide range of downstream effectors.
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Cites
Control of Effector CD8 + T Cell Function by the Transcription Factor Eomesodermin
Pearce, E. L., Mullen, A. C., Martins, G. A., Krawczyk, C. M., Hutchins, A. S., Zediak, V. P., Banica, M., DiCioccio, C. B., Gross, D. A., Mao, C.-A., et al. (2003) · Science · doi:10.1126/science.1090148 · Cited by 1,014
Tbr1 regulates differentiation of the preplate and layer 6
Hevner, R. F., Shi, L., Justice, N., Hsueh, Y.-P., Sheng, M., Smiga, S., Bulfone, A., Goffinet, A. M., Campagnoni, A. T., & Rubenstein, J. L. R. (2001) · Neuron · doi:10.1016/s0896-6273(01)00211-2 · Cited by 857
Jacobs, J. J. L., Keblusek, P., Robanus-Maandag, E., Kristel, P., Lingbeek, M., Nederlof, P. M., van Welsem, T., van de Vijver, M. J., Koh, E. Y., Daley, G. Q., et al. (2000) · Nature Genetics · doi:10.1038/81583 · Cited by 368
Hsueh, Y.-P., Wang, T.-F., Yang, F.-C., & Sheng, M. (2000) · Nature · doi:10.1038/35005118 · Cited by 355
Lingbeek, M. E., Jacobs, J. J. L., & van Lohuizen, M. (2002) · Journal of Biological Chemistry · doi:10.1074/jbc.m200403200 · Cited by 160
Characterization of the TBX5 binding site and analysis of mutations that cause Holt-Oram syndrome
Ghosh, T. K. (2001) · Human Molecular Genetics · doi:10.1093/hmg/10.18.1983 · Cited by 150
Tbx Genes Specify Posterior Digit Identity through Shh and BMP Signaling
Suzuki, T., Takeuchi, J., Koshiba-Takeuchi, K., & Ogura, T. (2004) · Developmental Cell · doi:10.1016/s1534-5807(03)00401-5 · Cited by 148
Coll, M., Seidman, J. G., & Müller, C. W. (2002) · Structure · doi:10.1016/s0969-2126(02)00722-0 · Cited by 121
Carlson, H. (2001) · Human Molecular Genetics · doi:10.1093/hmg/10.21.2403 · Cited by 108
Cited by
Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria
Hoogaars, W. M. H., Engel, A., Brons, J. F., Verkerk, A. O., de Lange, F. J., Wong, L. Y. E., Bakker, M. L., Clout, D. E., Wakker, V., Barnett, P., et al. (2007) · Genes & Development · doi:10.1101/gad.416007 · Cited by 409
Tbr1 regulates regional and laminar identity of postmitotic neurons in developing neocortex
Bedogni, F., Hodge, R. D., Elsen, G. E., Nelson, B. R., Daza, R. A. M., Beyer, R. P., Bammler, T. K., Rubenstein, J. L. R., & Hevner, R. F. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1002285107 · Cited by 322
Arnold, S. J., Hofmann, U. K., Bikoff, E. K., & Robertson, E. J. (2008) · Development · doi:10.1242/dev.014357 · Cited by 271
Tbx3 Represses E-Cadherin Expression and Enhances Melanoma Invasiveness
Rodriguez, M., Aladowicz, E., Lanfrancone, L., & Goding, C. R. (2008) · Cancer Research · doi:10.1158/0008-5472.can-08-0301 · Cited by 157
Suzuki, A., Sekiya, S., Büscher, D., Izpisúa Belmonte, J. C., & Taniguchi, H. (2008) · Development · doi:10.1242/dev.016634 · Cited by 136
Metadata
- Authors
- Naiche, L. A., Harrelson, Z., Kelly, R. G., & Papaioannou, V. E.
- Venue
- Annual Review of Genetics
- Publisher
- Annual Reviews
- Published
- 2005-12-01
- Volume
- 39
- Issue
- 1
- Pages
- 219-239
- ISSN
- 0066-4197 (ISSN-L)
- 1545-2948
- OpenAlex
- W2124478777
- Cited by
- 432
- References
- 9
- FWCI
- 1.30
- Type
- journal article
- Language
- en
- Open access
- closed
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- Naiche, L. A., Harrelson, Z., Kelly, R. G., & Papaioannou, V. E. (2005). T-Box Genes in Vertebrate Development. Annual Review of Genetics. https://doi.org/10.1146/annurev.genet.39.073003.105925
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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