The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
NEUTRALIZING ANTIVIRAL B CELL RESPONSES
Abstract
▪ Abstract Neutralizing antiviral B cell responses differ in various aspects from the many usually measured B cell responses specific for protein in adjuvants. In particular, such neutralizing antiviral B cell responses are more rapidly induced, reach higher titers, are longer lived, and are efficiently generated without adjuvants. Evidence is summarized here that the repetitiveness of many viral antigens is a key factor responsible for the efficiency of these B cell responses, amplifying B cells early and rapidly for potent IgM responses and also for efficient switching to IgG. The data reviewed indicate that B cells discriminate antigen patterns via the degree of surface Ig-cross-linking and use antigen repetitiveness as a self/nonself discriminator.
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Citations
Cites
The Protection: The Unit of Humoral Immunity Selected by Evolution
Cohn, M., & Langman, R. E. (1990) · Immunological Reviews · doi:10.1111/j.1600-065x.1990.tb00783.x · Cited by 238
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Vaccine delivery: a matter of size, geometry, kinetics and molecular patterns
Bachmann, M. F., & Jennings, G. T. (2010) · Nature Reviews Immunology · doi:10.1038/nri2868 · Cited by 2,106
Self-citationMulligan, M. J., Lyke, K. E., Kitchin, N., Absalon, J., Gurtman, A., Lockhart, S., Neuzil, K., Raabe, V., Bailey, R., Swanson, K. A., et al. (2020) · doi:10.1101/2020.06.30.20142570 · Cited by 1,569
Effects of protein aggregates: An immunologic perspective
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Metadata
- Authors
- Bachmann, M. F., & Zinkernagel, R. M.
- Venue
- Annual Review of Immunology
- Publisher
- Annual Reviews
- Published
- 1997-04
- Volume
- 15
- Issue
- 1
- Pages
- 235-270
- ISSN
- 0732-0582 (ISSN-L)
- 1545-3278
- OpenAlex
- W2119281067
- Cited by
- 471
- References
- 1
- FWCI
- 1.22
- Type
- journal article
- Language
- en
- Open access
- closed
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- Bachmann, M. F., & Zinkernagel, R. M. (1997). NEUTRALIZING ANTIVIRAL B CELL RESPONSES. Annual Review of Immunology. https://doi.org/10.1146/annurev.immunol.15.1.235
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
