Cited by 128Pregnancy and preeclampsia studiesNeurological Complications and SyndromesPregnancy-related medical research

The DOI matches its Crossref record; 47 of the 47 references it cites were found in a registry or an index.

Preeclampsia: Pathophysiology, Diagnosis, and Management

Lindheimer, M D, Katz, A I·1989·Annual Review of Medicine

DOI 10.1146/annurev.me.40.020189.001313

Open this paper in CoChat — free account

Abstract

Preeclampsia, a major cause of fetal and maternal morbidity and mortality, may be difficult to distinguish clinically from other hypertensive disorders of pregnancy. Signs helpful in its diagnosis include presentation during late gestation in a nullipara with edema and proteinuria, and one or more of the following: hemoconcentration, hypoalbuminemia, liver function and/or coagulation abnormalities, and increased urate levels. Measures that may prove useful in differentiating preeclampsia from less dangerous forms of hypertension are decreased antithrombin III levels, increments in serum iron and carboxyhemoglobin, and decreases in urinary calcium. Major pathophysiological features of preeclampsia are decreased cardiac output, pulmonary capillary wedge pressure, and plasma volume; and marked increases in peripheral vascular resistance, as well as exaggerated pressor responses to endogenous angiotensin II and catecholamines. Renal hemodynamics decrease, in part as a result of a characteristic morphological lesion in glomeruli ("endotheliosis"), and there may be increased vascular permeability leading to albumin loss from the intravascular space. When gestation is advanced, termination is the treatment of choice; when temporization is required, several antihypertensive medications whose safety and efficacy have been tested in pregnant women are available. Magnesium sulfate remains the drug of choice for impending convulsions (the eclamptic phase of the disease). Finally, the etiology of preeclampsia remains unknown, but a popular theory suggests that alterations in prostaglandin metabolism may be responsible for the hypertension and coagulopathy in this disorder. In this respect, prophylactic treatment with low doses of aspirin, which decrease platelet thromboxane production but spare endothelial prostacyclin release, may decrease the incidence of preeclampsia in "high-risk" populations.

Integrity signals

Registry

Crossref · 10.1146/annurev.me.40.020189.001313

Cites

47 of 47 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

This paper’s full text isn’t openly available, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

The Renin-Angiotensin System
Reid, I. A., Morris, B. J., & Ganong, W. F. (1978) · Annual Review of Physiology · doi:10.1146/annurev.ph.40.030178.002113 · Cited by 949
Maternal-perinatal outcome associated with the syndrome of hemolysis, elevated liver enzymes, and low platelets in severe preeclampsia-eclampsia
Sibai, B. M., Taslimi, M. M., El-Nazer, A., Amon, E., Mabie, B. C., & Ryan, G. M. (1986) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(86)90266-8 · Cited by 596
PREVENTION OF PRE-ECLAMPSIA BY EARLY ANTIPLATELET THERAPY
Beaufils, M., Donsimoni, R., Uzan, S., & Colau, J. C. (1985) · The Lancet · doi:10.1016/s0140-6736(85)92207-x · Cited by 470
The Parkland Memorial Hospital protocol for treatment of eclampsia: Evaluation of 245 cases
Pritchard, J. A., Cunningham, F. G., & Pritchard, S. A. (1984) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(84)90538-6 · Cited by 422
Hypertension in Pregnancy
Fisher, K. A., Luger, A., Spargo, B. H., & Lindheimer, M. D. (1981) · Medicine · doi:10.1097/00005792-198107000-00002 · Cited by 374
Self-citation
Preeclampsia is associated with a serum factor cytotoxic to human endothelial cells
Rodgers, G. M., Taylor, R. N., & Roberts, J. M. (1988) · American Journal of Obstetrics and Gynecology · doi:10.1016/s0002-9378(88)80169-8 · Cited by 278
Preeclampsia: a review of the role of prostaglandins.
Friedman, S. A. (1988) · PubMed · Cited by 255
PLACEBO-CONTROLLED TRIAL OF ATENOLOL IN TREATMENT OF PREGNANCY-ASSOCIATED HYPERTENSION
Rubin, P. C., Clark, D., Sumner, D., Low, R., Butters, L., Reynolds, B., Steedman, D. J., & Reid, J. L. (1983) · The Lancet · doi:10.1016/s0140-6736(83)91436-8 · Cited by 234
Hypocalciuria in Preeclampsia
Taufield, P. A., Aleš, K. L., Resnick, L. M., Druzin, M. L., Gertner, J. M., & Laragh, J. H. (1987) · New England Journal of Medicine · doi:10.1056/nejm198703193161204 · Cited by 212
The relationship between calcium intake and pregnancy-induced hypertension: Up-to-date evidence
Belizán, J. M., Villar, J., & Repke, J. T. (1988) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(88)90091-9 · Cited by 208

Show all 47 references

Sorted by citations

Hypoalbuminemia: Pathogenesis and Clinical Significance
Soeters, P. B., Wolfe, R. R., & Shenkin, A. (2019) · Journal of Parenteral and Enteral Nutrition · doi:10.1002/jpen.1451 · Cited by 1,448
Iron behaving badly: inappropriate iron chelation as a major contributor to the aetiology of vascular and other progressive inflammatory and degenerative diseases
Kell, D. B. (2009) · BMC Medical Genomics · doi:10.1186/1755-8794-2-2 · Cited by 554
National High Blood Pressure Education Program Working Group Report on High Blood Pressure in Pregnancy
(1990) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(90)90653-o · Cited by 441
Preeclampsia-Eclampsia: Clinical and Neuroradiographic Correlates and Insights into the Pathogenesis of Hypertensive Encephalopathy
Schwartz, R. B., Feske, S. K., Polak, J. F., Girolami, U. D., Iaia, A., Beckner, K. M., Bravo, S. M., Klufas, R. A., Chai, R. Y., & Jt, R. (2000) · Radiology · doi:10.1148/radiology.217.2.r00nv44371 · Cited by 388
Hemolytic Uremic Syndrome
Remuzzi, G., & Ruggenenti, P. (2012) · SpringerReference · doi:10.1007/springerreference_226547 · Cited by 267
The hemolytic uremic syndrome
Remuzzi, G., & Ruggenenti, P. L. (1995) · Kidney International · doi:10.1038/ki.1995.261 · Cited by 173
Peripheral blood concentrations of adiponectin, an adipocyte-specific plasma protein, in normal pregnancy and preeclampsia
Naruse, K., Yamasaki, M., Umekage, H., Sado, T., 阪本, 義., & Morikawa, H. (2004) · Journal of Reproductive Immunology · doi:10.1016/j.jri.2004.09.004 · Cited by 116
The Effect of Pregnancy on Renal Function: Physiology and Pathophysiology
Dafnis, E., & Sabatini, S. (1992) · The American Journal of the Medical Sciences · doi:10.1097/00000441-199203000-00011 · Cited by 112
Immune Thrombocytopenia in Pregnancy
Stavrou, E. X., & McCrae, K. R. (2009) · Hematology/Oncology Clinics of North America · doi:10.1016/j.hoc.2009.08.005 · Cited by 111
Genetics of Pre-Eclampsia
Cooper, D. W., Brennecke, S. P., & Wilton, A. N. (1993) · Hypertension in Pregnancy · doi:10.3109/10641959309031050 · Cited by 111
Clinical Pharmacokinetics of Vasodilators
Kirsten, R., Nelson, K., Kirsten, D., & Heintz, B. (1998) · Clinical Pharmacokinetics · doi:10.2165/00003088-199834060-00003 · Cited by 108
Left ventricular mechanics in preeclampsia
Lang, R. M., Pridjian, G. C., Feldman, T. E., Neumann, A., Lindheimer, M. D., & Borow, K. M. (1991) · American Heart Journal · doi:10.1016/0002-8703(91)90024-c · Cited by 89
Self-citation
Endothelial Adhesion Molecules and Leukocyte Integrins in Preeclamptic Patients
Haller, H. G., Ziegler, E.-M., Homuth, V., Dráb, M., Eichhorn, J., Nagy, Z., Busjahn, A., Vetter, K. J., & Luft, F. C. (1997) · Hypertension · doi:10.1161/01.hyp.29.1.291 · Cited by 82
Clinical Pharmacokinetics of Vasodilators
Kirsten, R., Nelson, K., Kirsten, D., & Heintz, B. (1998) · Clinical Pharmacokinetics · doi:10.2165/00003088-199835010-00002 · Cited by 81
Endothelial-cell permeability and protein kinase C in pre-eclampsia
Haller, H. G., Hempel, A., Homuth, V., Mandelkow, A., Busjahn, A., Maasch, C., Dráb, M., Lindschau, C., Jüpner, A., Vetter, K. J., et al. (1998) · The Lancet · doi:10.1016/s0140-6736(00)80012-4 · Cited by 65
Prevention and Treatment of Pregnancy-Associated Hypertension: What Have We Learned in the Last 10 Years?
Remuzzi, G., & Ruggenenti, P. L. (1991) · American Journal of Kidney Diseases · doi:10.1016/s0272-6386(12)80087-4 · Cited by 60
Role of dyslipidemia in preeclampsia—A review of lipidomic analysis of blood, placenta, syncytiotrophoblast microvesicles and umbilical cord artery from women with preeclampsia
Wojcik-Baszko, D., Charkiewicz, K., & Laudański, P. (2018) · Prostaglandins & Other Lipid Mediators · doi:10.1016/j.prostaglandins.2018.09.006 · Cited by 60
Oxidized and Free Whole Blood Thiols in Preeclampsia
Raijmakers, M. T. M., Zusterzeel, P. L. M., Roes, E. M., Steegers, E. A. P., MULDER, T. P. J., & Peters, W. H. M. (2001) · Obstetrics and Gynecology · doi:10.1016/s0029-7844(00)01127-3 · Cited by 57
Cardiovascular changes in preeclampsia
Hibbard, J. U., Shroff, S. G., & Lang, R. M. (2004) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2004.07.007 · Cited by 54
8 Volume homeostasis and osmoregulation in human pregnancy
Davison, J. M., & Lindheimer, M. D. (1989) · Baillière s Clinical Endocrinology and Metabolism · doi:10.1016/s0950-351x(89)80011-4 · Cited by 48
Self-citation
Enhanced [Ca2+]iin renal arterial smooth muscle cells of pregnant rats with reduced uterine perfusion pressure
Murphy, J. G., Herrington, J. N., Granger, J. P., & Khalil, R. A. (2003) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00247.2002 · Cited by 44
Effect of low-dose aspirin on vascular refractoriness in angiotensin-sensitive primigravid women
Wallenburg, H. C. S., Dekker, G. A., MAKOVITZ, J. W., & Rotmans, N. (1991) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(91)90678-k · Cited by 43
7 The role of prostaglandins in obstetrical disorders
Ylikorkala, O., & Viinikka, L. U. (1992) · Baillière s Clinical Obstetrics and Gynaecology · doi:10.1016/s0950-3552(05)80190-7 · Cited by 41
Hematocrit and plasma albumin levels difference may be a potential biomarker to discriminate preeclampsia and eclampsia in patients with hypertensive disorders of pregnancy
Dai, D., Cao, J., Yang, H., Sun, H.-M., Su, Y., Chen, Y., Fang, X., & Xu, W. (2016) · Clinica Chimica Acta · doi:10.1016/j.cca.2016.12.001 · Cited by 37
Disordered eicosanoid formation in pregnancy-induced hypertension.
Meagher, E. A., & FitzGerald, G. A. (1993) · Circulation · doi:10.1161/01.cir.88.3.1324 · Cited by 36
Clinical significance of serum albumin level in pregnancy‐related hypertension
Seong, W. J., Chong, G. O., Hong, D. G., Lee, T. H., Lee, Y. S., Cho, Y. L., Chun, S. S., & Park, I. S. (2010) · Journal of obstetrics and gynaecology research · doi:10.1111/j.1447-0756.2010.01296.x · Cited by 34
Random urine protein/creatinine ratio readily predicts proteinuria in preeclampsia
Park, J.-H., Chung, D., Cho, H. Y., Kim, Y. H., Son, G., Park, Y.-W., & Kwon, J. (2013) · Obstetrics & Gynecology Science · doi:10.5468/ogs.2013.56.1.8 · Cited by 33
Low plasma levels of oxidized low density lipoprotein in preeclampsia
Raijmakers, M. T. M., Tits, B. J. H. V., Hak-Lemmers, H. L. M., Roes, E. M., Steegers, E. A. P., & Peters, W. H. M. (2004) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.1080/j.0001-6349.2004.00539.x · Cited by 32
Multiple Pregnancies in CKD Patients
Piccoli, G. B., Arduino, S., Attini, R., Parisi, S., Fassio, F., Biolcati, M., Pagano, A., Bossotti, C., Vasario, E., Borgarello, V., et al. (2012) · Clinical Journal of the American Society of Nephrology · doi:10.2215/cjn.02550312 · Cited by 32
Hypertensive Drugs in Pregnancy
Walker, J. J. (1991) · Clinics in Perinatology · doi:10.1016/s0095-5108(18)30499-8 · Cited by 32
Preeclampsia and calcium adenosine triphosphatase activity of red blood cell ghosts
Nardulli, G., Proverbio, F., Limongi, F., Marı́n, R., & Proverbio, T. (1994) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(94)90161-9 · Cited by 31
Eclamptic encephalopathy: MRI, including diffusion-weighted images
Watanabe, Y., MITOMO, M., Tokuda, Y., Yoshida, K., Choi, S., Hosoki, T., & Ban, C. (2002) · Neuroradiology · doi:10.1007/s00234-002-0867-y · Cited by 27
Cellular-Free Magnesium Depletion in Brain and Muscle of Normal and Preeclamptic Pregnancy
Resnick, L. M., Barbagallo, M., Bardicef, M., Bardicef, O., Sorokin, Y., Evelhoch, J. L., Dominguez, L. J., Mason, B. A., & Cotton, D. B. (2004) · Hypertension · doi:10.1161/01.hyp.0000137592.76535.8c · Cited by 27
Posterior reversible encephalopathy syndrome: differences between pregnant and non-pregnant patients
Marrone, L. C. P., Gadonski, G., Diogo, L. P., Brunelli, J. P. F., Martins, W. A., Laguna, G. D. O., Bahlis, L. F., Filho, J. R. H., da Costa, B. E. P., Poli‐de‐Figueiredo, C. E., et al. (2014) · Neurology International · doi:10.4081/ni.2014.5376 · Cited by 26
[Ca2+]isignaling in renal arterial smooth muscle cells of pregnant rat is enhanced during inhibition of NOS
Murphy, J. G., Fleming, J. B., Cockrell, K. L., Granger, J. P., & Khalil, R. A. (2001) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.2001.280.1.r87 · Cited by 26
Serum antioxidant micronutrient levels in pre-eclamptic pregnant women in Enugu, south-East Nigeria: a comparative cross-sectional analytical study
Enebe, J. T., Dim, C. C., Ugwu, E. O., Enebe, N. O., Meka, I. A., Obioha, K. C., Eleje, G. U., & Nwagha, U. I. (2020) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-020-03081-w · Cited by 24
Serum Levels of Asymmetric Dimethylarginine, Vascular Endothelial Growth Factor, and Nitric Oxide Metabolite Levels in Preeclampsia Patients
Noorbakhsh, M., Kianpour, M., & Nematbakhsh, M. (2013) · ISRN Obstetrics and Gynecology · doi:10.1155/2013/104213 · Cited by 25
Marasmius oreades lectin induces renal thrombotic microangiopathic lesions
Warner, R. L., Winter, H. C., Speyer, C. L., Varani, J., oldstein, I. J., Murphy, H. S., & Johnson, K. J. (2004) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2004.04.003 · Cited by 24
Central and peripheral hemodynamics in severe preeclampsia
Yang, J., Yang, Y., & Wang, K. (1996) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.3109/00016349609033302 · Cited by 24
Review article
Kurjak, A., Kupesic, S. P., Hafner, T., Kos, M., Kostović‐Knežević, L., & Grbeša, Đ. (1997) · Journal of Perinatal Medicine · doi:10.1515/jpme.1997.25.3.225 · Cited by 23
Thiol status and antioxidant capacity in women with a history of severe pre‐eclampsia
Raijmakers, M. T. M., Roes, E. M., Zusterzeel, P. L. M., Steegers, E. A. P., & Peters, W. H. M. (2004) · BJOG An International Journal of Obstetrics & Gynaecology · doi:10.1111/j.1471-0528.2004.00051.x · Cited by 21
Conservative treatment of mild and moderate hypertension in pregnancy
Hjertberg, R., Belfrage, P., & Hanson, U. (1992) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.3109/00016349209021092 · Cited by 21
Lipid Rafts and Cytoskeletal Proteins in Placental Microvilli Membranes from Preeclamptic and IUGR Pregnancies
Riquelme, G., Vallejos, C., Gregorio, N. D., Morales, B., Godoy, V., Berrios, M., Bastías, N., & Carolina, R. (2011) · The Journal of Membrane Biology · doi:10.1007/s00232-011-9369-3 · Cited by 20
Increased incidence of preeclampsia in mothers of advanced age conceiving by oocyte donation
Dior, U. P., Laufer, N., Chill, H. H., Granovsky‐Grisaru, S., Yagel, S., Yaffe, H., & Gielchinsky, Y. (2018) · Archives of Gynecology and Obstetrics · doi:10.1007/s00404-017-4616-1 · Cited by 19
The ameliorative effect of angiotensin 1-7 on experimentally induced-preeclampsia in rats: Targeting the role of peroxisome proliferator-activated receptors gamma expression & asymmetric dimethylarginine
El‐Saka, M. H., Madi, N. M., Ibrahim, R. R., Alghazaly, G. M., Elshwaikh, S. L., & El-Bermawy, M. I. (2019) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2019.07.006 · Cited by 19
Thrombotic microangiopathies
Ruggenenti, P., & Remuzzi, G. (1991) · Critical Reviews in Oncology/Hematology · doi:10.1016/1040-8428(91)90028-b · Cited by 18
Clinical biochemistry of preeclampsia and related liver diseases of pregnancy: A review
Freund, G. G., & Arvan, D. A. (1990) · Clinica Chimica Acta · doi:10.1016/0009-8981(90)90015-k · Cited by 17
Inactive Hepatitis B Carrier and Pregnancy Outcomes: A Systematic Review and Meta-analysis.
Keramat, A., Younesian, M., Fesharaki, M. G., Hasani, M., Mirzaei, S., Ebrahimi, E., Alavian, S. M., & Mohammadi, F. (2017) · Europe PMC (PubMed Central) · Cited by 16
Serum 25-hydroxyvitamin D, calcium, and calcium-regulating hormones in preeclamptics and controls during first day postpartum
Dalmar, A., Raff, H., Chauhan, S. P., Singh, M., & Siddiqui, D. S. (2014) · Endocrine · doi:10.1007/s12020-014-0296-9 · Cited by 14
Viability of primary term cytotrophoblast cell culture in normoxia and hypoxia
Depoix, C. L., Barret, L. A., Hubinont, C., & Debiève, F. (2012) · Molecular Human Reproduction · doi:10.1093/molehr/gas042 · Cited by 13
Prospects of electrochemical immunosensors for early diagnosis of preeclampsia
Suman, P., Gandhi, S., Kumar, P., & Garg, K. (2016) · American Journal of Reproductive Immunology · doi:10.1111/aji.12584 · Cited by 13
Circulating levels of ciliary neurotrophic factor in normal pregnancy and preeclampsia.
Akahori, Y., Takamoto, N., Masumoto, A., Inoue, S., Nakatsukasa, H., Masuyama, H., & Hiramatsu, Y. (2010) · PubMed · doi:10.18926/amo/32847 · Cited by 11
The value of antithrombin-III and fibronectin in hypertensive disorders of pregnancy
Şen, C., Madazh, R., Kavuzlu, C., Ocak, V., & Tolun, N. (1994) · Journal of Perinatal Medicine · doi:10.1515/jpme.1994.22.1.29 · Cited by 11
Altered Expressions of AQP3 and ADP Are Closely Related with the Risk of Preeclampsia Occurrence
Zhou, J., Zhang, D., Bai, J., Li, Z., & Chen, Y. (2020) · Gynecologic and Obstetric Investigation · doi:10.1159/000509161 · Cited by 10
Differential Effects of Sera from Normotensive and Hypertensive Pregnant Women on Ca2+ Metabolism in Normal Vasular Smooth Muscle Cells
Green, J., Assady, S., Nakhoul, F. M., Bick, T., Jakobi, P., & Abassi, Z. A. (2000) · Journal of the American Society of Nephrology · doi:10.1681/asn.v1171188 · Cited by 10
Cardiovascular Alterations in Normal and Preeclamptic Pregnancy
Hibbard, J. U., Shroff, S. G., & Cunningham, F. G. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-407866-6.00014-6 · Cited by 10
Hypoproteinemia as a parameter of poor perinatal/neonatal outcomes in women with preeclampsia diagnosed as hypertension plus proteinuria
Morikawa, M., Mayama, M., Saito, Y., Nakagawa‐Akabane, K., Umazume, T., Chiba, K., Kawaguchi, S., Cho, K., & Watari, H. (2020) · Pregnancy Hypertension · doi:10.1016/j.preghy.2020.05.012 · Cited by 10
The Treatment of Hypertension in Pregnancy
Knott, C. (1991) · Clinical Pharmacokinetics · doi:10.2165/00003088-199121040-00001 · Cited by 10
A systematic review with network meta-analysis on mono strategy of anaesthesia for preeclampsia in caesarean section
Chu, C., Liao, A. H.-W., Chen, C., Lin, Y.-C., & Kang, Y. (2021) · Scientific Reports · doi:10.1038/s41598-021-85179-5 · Cited by 11
Early-onset preeclampsia – The impact of antiphospholipid antibodies on disease severity
Zemet, R., Dulitzki, M., Baum, M., Friedman, H. O., Morag, I., & Simchen, M. J. (2021) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/j.ejogrb.2021.06.006 · Cited by 11
Differential Expression of Potassium Channels in Placentas from Normal and Pathological Pregnancies: Targeting of the Kir 2.1 Channel to Lipid Rafts
Riquelme, G., Gregorio, N. D., Vallejos, C., Berrios, M., & Morales, B. (2012) · The Journal of Membrane Biology · doi:10.1007/s00232-012-9422-x · Cited by 9
Immunological changes in pregnancy-induced hypertension
Chen, G., Wilson, R., Cumming, G., Walker, J. J., & McKillop, J. H. (1994) · European Journal of Obstetrics & Gynecology and Reproductive Biology · doi:10.1016/0028-2243(94)90132-5 · Cited by 9
Minidosis de ácido acetil salicílico como tratamiento profiláctico de la enfermedad hipertensiva del embarazo
Hernández, F., Martínez, M. F., Adriana Camero, L., & Pinzón, J. A. (1996) · Revista Colombiana de Obstetricia y Ginecología · doi:10.18597/rcog.1446 · Cited by 8
The Impact of Severity of Antenatal Anaemia on Maternal and Perinatal Outcome in Hospital Serdang, Central Malaysia
Tusimin, M., Yazit, A., Zainulddin, N. S., Vaiappuri, V. S. K., & Noor, S. M. (2016) · Journal of Pregnancy and Child Health · doi:10.4172/2376-127x.1000291 · Cited by 8
The role of interleukin-6 promoter polymorphism -174G/C in Saudi women with hypertensive disorders of pregnancy
Bayoumy, N. M. K., Al-Sharaidh, A. S., Babay, Z. A., & Abdulgader, A. (2013) · Saudi Medical Journal · doi:10.15537/1658-3175.5784 · Cited by 8
The Pre-Eclampsia Ontology: A Disease Ontology Representing the Domain Knowledge Specific to Pre-Eclampsia
Mizuno, S., Ogishima, S., Nishigori, H., Jamieson, D. G., Verspoor, K. M., Tanaka, H., Yaegashi, N., & Nakaya, J. (2016) · PLoS ONE · doi:10.1371/journal.pone.0162828 · Cited by 8
Factors Influencing Maternal Mortality from Severe Preeclampsia and Eclampsia
Khusen, D. (2016) · Indonesian Journal of Obstetrics and Gynecology · doi:10.32771/inajog.v36i2.293 · Cited by 7
Muscarinic Cholinergic Receptors and Acetylcholinesterase Activity in Umbilical Artery and Vein in Pregnancy-Induced Hypertension (Pre-Eclampsia)
Tayebati, S. K., Giannella, M., Indraccolo, S. R., Pigini, M., Sabbatini, M., Zaccheo, D., & Amenta, F. (1997) · Clinical and Experimental Hypertension · doi:10.3109/10641969709083213 · Cited by 7
Acute Pulmonary Edema in an Eclamptic Pregnant Patient: A Rare Case of Takotsubo Syndrome
Karamchandani, K., Bortz, B., & Vaida, S. J. (2016) · American Journal of Case Reports · doi:10.12659/ajcr.898937 · Cited by 7
The soluble fms-like tyrosin kinase-1 (sFLT-1) to placental growth factor (PIGF) ratio as a possible indicator for the severity of preeclampsia - single institution experience
Müller, A., Horvat, V., Vulin, M., Mandić, S., Šerić, V., & Vidosavljević, D. (2018) · Medicinski Glasnik · doi:10.17392/994-19 · Cited by 7
FACTORES DE RIESGO Y CONDICIONES PERINATALES DE LA PREECLAMPSIA - ECLAMPSIA
Hernández, W. G., Castillo, Y. C., Ávila, E. B., & Saeta, Y. F. (2014) · 16 de abril/Revista 16 de abril · Cited by 6
Takotsubo syndrome occurring concomitantly with pre‐eclampsia: A case report
Horie, K., Takahashi, H., Fujimoto, Y., Kaneko, D., Yada, Y., & Matsubara, S. (2019) · Journal of obstetrics and gynaecology research · doi:10.1111/jog.13904 · Cited by 6
Zerebrale Vasospasmen mit hämodynamischen Infarkten als Komplikation eines HELLP-Syndroms
Harscher, S., Witte, O. W., Möller, U., Bloos, G., Pfleiderer, S. O. R., & Terborg, C. (2003) · Der Nervenarzt · doi:10.1007/s00115-003-1581-7 · Cited by 6
Investigation of the role of the NO–cGMP pathway on YC-1 and DEA/NO effects on thoracic aorta smooth muscle responses in a rat preeclampsia model
Turgut, N. H., Temiz, T. K., Turgut, B., Karadaş, B., Parlak, M., & Bağcıvan, İ. (2013) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/cjpp-2013-0086 · Cited by 6
Cardiovascular Alterations in Normal and Preeclamptic Pregnancy
Shroff, S. G., Hauspurg, A. K., Hibbard, J. U., & Conrad, K. P. (2022) · Elsevier eBooks · doi:10.1016/b978-0-12-818417-2.00007-5 · Cited by 6
Comparative transcriptome analysis of embryo invasion in the mink uterus
Cao, X., Xu, C., Zhang, Y., Wei, H., Liu, Y., Cao, J., Zhao, W., Bao, K., & Wu, Q. (2018) · Placenta · doi:10.1016/j.placenta.2018.11.004 · Cited by 6
Role of Prostaglandins in Pre‐Eclampsia
Toppozada, M. (1990) · Acta Obstetricia Et Gynecologica Scandinavica · doi:10.3109/00016349009013296 · Cited by 6
Normal and Abnormal Placentation
Korourian, S., & Casas, L. E. D. L. (2007) · doi:10.1002/9780470753293.ch3 · Cited by 6
Hemolytic Uremic syndrome associated with pregnancy: Outcome from acute Kidney Injury
Naqvi, R. (2020) · Pakistan Journal of Medical Sciences · doi:10.12669/pjms.36.6.2931 · Cited by 5
Das neurologische Spektrum von Präeklampsie und Eklampsie
Dittmar, G. (1999) · Der Nervenarzt · doi:10.1007/s001150050545 · Cited by 5
Magnesium Sulfate and Preeclampsia or Eclampsia
Lindheimer, M. D. (1989) · Archives of Neurology · doi:10.1001/archneur.1989.00520470014005 · Cited by 5
Self-citation
Thrombotic Microangiopathy
Ruggenenti, P. L., & Remuzzi, G. (1998) · Springer eBooks · doi:10.1007/978-1-4757-6632-5_31 · Cited by 5
Loss of dopamine D1‐like receptors in the umbilical artery of pre‐eclamptic subjects
Almeida, J. A. F. D., Cavallotti, C. A. P., Leite, L. P., Rícci, A., Zaccheo, D., & Amenta, F. (1994) · Journal of Autonomic Pharmacology · doi:10.1111/j.1474-8673.1994.tb00616.x · Cited by 4
Preeclampsia. Still an enigma.
Duda, J. (1996) · PubMed Central · Cited by 4
Delayed diagnosis of PRES and eclampsia in a concealed pregnancy
Dağ, Z. Ö., Şimşek, Y., Türkel, Y., Tulmaç, Ö. B., & Işık, Y. (2014) · Pan African Medical Journal · doi:10.11604/pamj.2014.19.299.5628 · Cited by 3
The underlying metabolism of hypoalbuminemia and its clinical effects
Soeters, P. B., & de Leeuw, P. W. (2021) · Elsevier eBooks · doi:10.1016/b978-0-12-820205-0.00010-4 · Cited by 3
Anatomie pathologique de l’insuffisance vasculaire utéroplacentaire
Carles, D., Pelluard, F., André, G., Naudion, S., Poingt, M., Castain, C., & Sauvestre, F. (2013) · Annales de Pathologie · doi:10.1016/j.annpat.2013.04.018 · Cited by 3
Relationship between central venous pressure and pulmonary capillary wedge pressure in severely toxemic patients
Téllez, R. T., & Curiel, R. (1991) · American Journal of Obstetrics and Gynecology · doi:10.1016/0002-9378(91)90130-j · Cited by 3
Lactate dehydrogenase isoenzymes in serum of patients with complicated by the HELLP syndrome
Beyer, C. (1991) · Clinica Chimica Acta · doi:10.1016/0009-8981(91)90263-c · Cited by 3
Calcium Supplementation Prevents Hypertensive Disorders of Pregnancy
(2009) · Nutrition Reviews · doi:10.1111/j.1753-4887.1992.tb01335.x · Cited by 2
Clinical significance of severe proteinuria in preeclampsia: a multicenter study of maternal and neonatal outcomes
Morikawa, M., Ohkuchi, A., Iriyama, T., Mimura, K., Watanabe, K., Ushida, T., Nohira, T., Matsubara, K., Kawabata, I., Maki, S., et al. (2025) · Hypertension Research · doi:10.1038/s41440-025-02360-3 · Cited by 2
Critical Illness in Pregnancy
Hogarth, D. K., & Hall, J. (2009) · Humana Press eBooks · doi:10.1007/978-1-59745-445-2_21 · Cited by 2
The hemolytic uremic syndrome as a complication of adriamycin nephropathy
Viero, R. M., & Soares, V. A. (1998) · Renal Failure · doi:10.3109/08860229809045148 · Cited by 2
The complex evaluation of lipid metabolism and blood coagulation system indicators for prediction and early diagnosis of the preeclampsia
Aksonova, A. V., Венцківська, І. Б., Platonova, T. M., Колесникова, И. М., & Наложитова, О. О. (2016) · ScienceRise Medical Science · doi:10.15587/2519-4798.2016.87849 · Cited by 2
Cardiovascular Alterations in Normal and Preeclamptic Pregnancy
Hibbard, J. U., Shroff, S. G., & Lindheimer, M. D. (2009) · Elsevier eBooks · doi:10.1016/b978-0-12-374213-1.00014-8 · Cited by 2
Self-citation
Arterial stiffness and pulsatile hemodynamics in pregnancy and pregnancy-related vascular complications
Daskalopoulou, S. S. (2022) · Elsevier eBooks · doi:10.1016/b978-0-323-91391-1.00042-x · Cited by 2
The intensive care management of severe pregnancy induced hypertension
Mourad, O. (1992) · Australian Critical Care · doi:10.1016/s1036-7314(92)70012-5 · Cited by 2
Adverse effects of exposure to air pollutants during fetal development and early life : with focus on pre-eclampsia, preterm delivery, and childhood asthma
Olsson, D. (2014) · KTH Publication Database DiVA (KTH Royal Institute of Technology) · Cited by 2
Vitamin D Binding Protein as screening biomarker candidate for late-onset preeclampsia without intrauterine growth restriction during 16 week of gestation.
Nejadi, N., Hantoushzadeh, S., Mohammadpoor Masti, S., Sadat Hosseini, Z., Mousavi, M., Gorgani‐Firuzjaee, S., Zali, H., Rezaei–Tavirani, M., & Golmohammadi, T. (2015) · Archives of Advances in Biosciences · doi:10.22037/jps.v6i1.8182 · Cited by 1
Current Prescribing Pattern of Antihypertensive Drugs in Preeclampsia
Sarker, S. K., Ganesan, K., & Paul, R. (2015) · International Journal of Integrative Medical Sciences · doi:10.16965/ijims.2015.114 · Cited by 1

Authors: Lindheimer, M. D., & Katz, A. I.
Affiliations: University of Chicago (US)
Venue: Annual Review of Medicine
Publisher: Annual Reviews
Published: 1989-02
Volume: 40
Issue: 1
Pages: 233-250
ISSN: 0066-4219 (ISSN-L)
1545-326X
DOI: 10.1146/annurev.me.40.020189.001313
OpenAlex: W2115403364
Cited by: 128
References: 47
Citations by year: 2025: 1 · 2024: 1 · 2023: 1 · 2022: 2 · 2021: 6 · 2020: 5 · 2019: 5 · 2018: 8 · 2017: 1 · 2016: 11 · 2015: 2 · 2014: 7 · 2013: 6 · 2012: 4
FWCI: 12.92
Type: journal article
Language: en
Open access: closed
Locations: Annual Review of Medicine (publishedVersion)
PubMed (publishedVersion)
Funders: Eunice Kennedy Shriver National Institute of Child Health and Human Development (HD-24498)
Topics: Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
Health Sciences › Medicine › Clinical Neurology › Neurological Complications and Syndromes
Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy-related medical research
Keywords: preeclampsia, hypertensive disorders of pregnancy, pathophysiology, proteinuria, endotheliosis, antithrombin III, magnesium sulfate, eclampsia, antihypertensive drugs in pregnancy, aspirin prophylaxis, prostaglandin metabolism, thrombocytopenia, systemic vascular resistance, abortion
MeSH terms: Antihypertensive Agents, Diagnosis, Differential, Eclampsia, Female, Hemodynamics, Humans, Magnesium Sulfate, Pre-Eclampsia, Pregnancy, Dinoprostone

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Preeclampsia: Pathophysiology, Diagnosis, and Management

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks