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Positron Emission Tomography Scanning: Current and Future Applications
Abstract
▪ Abstract Whole-body positron emission tomography (PET) imaging with 18 F deoxyglucose (FDG) is a molecular imaging modality that detects metabolic alterations in tumor cells that are common to neoplastic cells. FDG-PET has recently been approved by the Health Care Finance Administration for Medicare reimbursement for diagnosing, staging, and restaging lung cancer, colorectal cancer, lymphoma, melanoma, head and neck cancer, and esophageal cancer. This review discusses the scientific evidence that led to the emergence of PET imaging as an accepted clinical tool in patients with solitary pulmonary nodules, lung cancer, colorectal cancer, melanoma, lymphoma, breast cancer, and other cancers. When possible, we compare the performance of PET to that of anatomical imaging. We discuss future clinical applications of this imaging modality.
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Cited by
Why Do Cancers Have High Aerobic Glycolysis?
Gatenby, R. A., & Gillies, R. J. (2004) · Nature reviews. Cancer · doi:10.1038/nrc1478 · Cited by 4,784
Regulation of cancer cell metabolism
Cairns, R. A., Harris, I. S., & Mak, T. W. (2011) · Nature Reviews Cancer · doi:10.1038/nrc2981 · Cited by 4,744
Artificially engineered magnetic nanoparticles for ultra-sensitive molecular imaging
Lee, J.-H., Huh, Y.-M., Jun, Y.-W., Seo, J.-W., Jang, J.-T., Song, H.-T., Kim, S., Cho, E.-J., Yoon, H.-G., Suh, J.-S., et al. (2007) · Nature Medicine · doi:10.1038/nm1467 · Cited by 1,897
Energy metabolism in tumor cells
Moreno‐Sánchez, R., Rodríguez‐Enríquez, S., Marín‐Hernández, A., & Saavedra, E. (2007) · The FEBS Journal · doi:10.1111/j.1742-4658.2007.05686.x · Cited by 1,082
Ciernik, I. F., Dizendorf, E., Baumert, B. G., Reiner, B., Burger, C., Davis, J. B., Lütolf, U. M., Steinert, H. C., & Von Schulthess, G. K. (2003) · International Journal of Radiation Oncology*Biology*Physics · doi:10.1016/s0360-3016(03)00346-8 · Cited by 543
Metadata
- Authors
- Czernin, J., & Phelps, M. E.
- Venue
- Annual Review of Medicine
- Publisher
- Annual Reviews
- Published
- 2002-02
- Volume
- 53
- Issue
- 1
- Pages
- 89-112
- ISSN
- 0066-4219 (ISSN-L)
- 1545-326X
- OpenAlex
- W2112269002
- Cited by
- 328
- References
- 0
- FWCI
- 2.02
- Type
- journal article
- Language
- en
- Open access
- closed
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- Czernin, J., & Phelps, M. E. (2002). Positron Emission Tomography Scanning: Current and Future Applications. Annual Review of Medicine. https://doi.org/10.1146/annurev.med.53.082901.104028
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
