The DOI matches its Crossref record; 2 of the 2 references it cites were found in a registry or an index.
The Small RNA Regulators of Escherichia coli : Roles and Mechanisms
Abstract
▪ Abstract Small noncoding RNAs have been found in all organisms, primarily as regulators of translation and message stability. The most exhaustive searches have taken place in E. coli, resulting in identification of more than 50 small RNAs, or 1%–2% of the number of protein-coding genes. One large class of these small RNAs uses the RNA chaperone Hfq; members of this class act by pairing to target messenger RNAs. Among the members of this class are DsrA and RprA, which positively regulate rpoS translation, OxyS, which negatively regulates rpoS translation and fhlA translation, RyhB, which reapportions iron use in the cell by downregulating translation of many genes that encode Fe-containing proteins, and Spot 42, which changes the polarity of translation in the gal operon. The promoters of these small RNAs are tightly regulated, frequently as part of well-understood regulons. Lessons learned from the study of small RNAs in E. coli can be applied to finding these important regulators in other organisms.
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Cites
Role of a peptide tagging system in degradation of proteins synthesized from damaged messenger RNA
Keiler, K. C., Waller, P. R. H., & Sauer, R. T. (1996) · Science · doi:10.1126/science.271.5251.990 · Cited by 1,125
Identification of novel small RNAs using comparative genomics and microarrays
Wassarman, K. M., Repoila, F., Rosenow, C., Storz, G., & Gottesman, S. (2001) · Genes & Development · doi:10.1101/gad.901001 · Cited by 723
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Cited by
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Correlation of mRNA and protein in complex biological samples
Maier, T., Güell, M., & Serrano, L. (2009) · FEBS Letters · doi:10.1016/j.febslet.2009.10.036 · Cited by 1,802
Makarova, K. S., Grishin, N. V., Shabalina, S. A., Wolf, Y. I., & Koonin, E. V. (2006) · Biology Direct · doi:10.1186/1745-6150-1-7 · Cited by 1,199
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Wilderman, P. J., Sowa, N. A., FitzGerald, D. J., FitzGerald, P. C., Gottesman, S., Ochsner, U. A., & Vasil, M. L. (2004) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0403423101 · Cited by 455
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Metadata
- Authors
- Gottesman, S.
- Venue
- Annual Review of Microbiology
- Publisher
- Annual Reviews
- Published
- 2004-10-01
- Volume
- 58
- Issue
- 1
- Pages
- 303-328
- ISSN
- 0066-4227 (ISSN-L)
- 1545-3251
- OpenAlex
- W2130168792
- Cited by
- 586
- References
- 2
- FWCI
- 3.99
- Type
- journal article
- Language
- en
- Open access
- closed
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