The DOI matches its Crossref record; 229 of the 229 references it cites were found in a registry or an index.
NEUROTROPHINS AND SYNAPTIC PLASTICITY
Abstract
▪ Abstract Despite considerable evidence that neuronal activity influences the organization and function of circuits in the developing and adult brain, the molecular signals that translate activity into structural and functional changes in connections remain largely obscure. This review discusses the evidence implicating neurotrophins as molecular mediators of synaptic and morphological plasticity. Neurotrophins are attractive candidates for these roles because they and their receptors are expressed in areas of the brain that undergo plasticity, activity can regulate their levels and secretion, and they regulate both synaptic transmission and neuronal growth. Although numerous experiments show demonstrable effects of neurotrophins on synaptic plasticity, the rules and mechanisms by which they exert their effects remain intriguingly elusive.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“To act as a mediator of activity-dependent plasticity in the central nervous system (CNS), neurotrophins need to be released and to act in an activity-dependent manner10,35,36.”
From Neuronal plasticity and neurotrophic factors in drug responses (2017) · cites this paper as [36]
Citations
Cites
Items 201–229 of 229
Critical period control in sensory cortex
Fox, K. D., & Zahs, K. R. (1994) · Current Opinion in Neurobiology · doi:10.1016/0959-4388(94)90040-x · Cited by 67
Baker, R. E., Dijkhuizen, P. A., van Pelt, J., & Verhaagen, J. (1998) · European Journal of Neuroscience · doi:10.1046/j.1460-9568.1998.00118.x · Cited by 67
Ruit, K. G., & Snider, W. D. (1991) · The Journal of Comparative Neurology · doi:10.1002/cne.903140110 · Cited by 64
Cerebellar LTD: A Molecular Mechanism of Behavioral Learning?
Lisberger, S. G. (1998) · Cell · doi:10.1016/s0092-8674(00)81397-5 · Cited by 63
Domenici, L., Cellerino, A., Berardi, N., Cattaneo, A., & Maffei, L. (1994) · Neuroreport · doi:10.1097/00001756-199410270-00013 · Cited by 63
Modulation of sodium-channel mRNA levels in rat skeletal muscle.
Cooperman, S. S., Grubman, S. A., Barchi, R. L., Goodman, R. H., & Mandel, G. (1987) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.84.23.8721 · Cited by 61
Numb Diverts Notch Pathway Off the Tramtrack
Campos‐Ortega, J. A. (1996) · Neuron · doi:10.1016/s0896-6273(00)80274-3 · Cited by 61
Domenici, L., Cellerino, A., & Maffei, L. (1993) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1993.0004 · Cited by 60
Glutamate receptor agonists enhance the expression of BDNF mRNA in cultured cerebellar granule cells
Bessho, Y., Nakanishi, S., & Nawa, H. (1993) · Molecular Brain Research · doi:10.1016/0169-328x(93)90190-z · Cited by 60
Neurotrophins Differentially Regulate Voltage-Gated Ion Channels
Lesser, S. S., Sherwood, N. T., & Lo, D. C. (1997) · Molecular and Cellular Neuroscience · doi:10.1006/mcne.1997.0656 · Cited by 59
Self-citationStimulation of GABAergic neuron differentiation by NT-4/5 in cultures of rat cerebral cortex
Widmer, H. R., & Hefti, F. F. (1994) · Developmental Brain Research · doi:10.1016/0165-3806(94)90114-7 · Cited by 58
LTP: Desperately Seeking Resolution
Malinow, R. (1994) · Science · doi:10.1126/science.7973700 · Cited by 56
O'Lague, P. H., Huttner, S. L., Vandenberg, C. A., Morrison‐Graham, K., & HORN, R. C. V. (1985) · Journal of Neuroscience Research · doi:10.1002/jnr.490130120 · Cited by 53
Non target-derived roles of the neurotrophins
Acheson, A. L., & Lindsay, R. M. (1996) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.1996.0037 · Cited by 52
Oppenheim, R. W. (1996) · Neurochemical Research · doi:10.1007/bf02532299 · Cited by 51
Paracrine and autocrine actions of neurotrophic factors
Davies, A. M. (1996) · Neurochemical Research · doi:10.1007/bf02532296 · Cited by 50
Berardi, N., Domenici, L., Parisi, V., Pizzorusso, T., Cellerino, A., & Maffei, L. (1993) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1993.0003 · Cited by 47
Modulation of a voltage-activated potassium channel by peptide growth factor receptors
Timpe, L. C., & Fantl, W. J. (1994) · Journal of Neuroscience · doi:10.1523/jneurosci.14-03-01195.1994 · Cited by 46
Dourado, M., & Dryer, S. E. (1994) · The Journal of Physiology · doi:10.1113/jphysiol.1994.sp020029 · Cited by 40
Focal Delivery of Neurotrophins into the Central Nervous System Using Fluorescent Latex Microspheres
Riddle, D. R., Katz, L. C., & Lo, D. C. (1997) · BioTechniques · doi:10.2144/97235rr02 · Cited by 38
Self-citationAndjelkovic, A. V., & Pachter, J. S. (1998) · Journal of Neuroscience Research · doi:10.1002/(sici)1097-4547(19980215)51:4 · Cited by 36
Neurotrophin regulation of ionic currents and cell size depends on cell context
Sherwood, N. T., Lesser, S. S., & Lo, D. C. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.11.5917 · Cited by 33
Self-citationStevens, C. F., & Sullivan, J. (1998) · Current Biology · doi:10.1016/s0960-9822(98)70097-1 · Cited by 32
Pollock, J. D., & Rane, S. G. (1996) · Journal of Biological Chemistry · doi:10.1074/jbc.271.14.8008 · Cited by 29
Yuzaki, M., Furuichi, T., Mikoshiba, K., & Kagawa, Y. (1994) · Learning & Memory · doi:10.1101/lm.1.4.230 · Cited by 14
Endogenous brain-derived neurotrophic factor is anterogradely transported in primary sensory neurons
Zhou, X. (1996) · Neuroscience · doi:10.1016/s0306-4522(96)00237-0 · Cited by 14
Lindholm, D., Heumann, R., Borasio, G. D., & Thoenen, H. (1989) · Open access LMU (Ludwid Maxmilian's Universitat Munchen) · Cited by 8
NGF synthesis and NGF receptor expression in the embryonic mouse trigeminal system.
Davies, A. M. (1990) · PubMed · Cited by 7
Baev, K. V., Berezovskii, V. K., Kalunov, V. N., Luschitskaya, N. I., Rusin, K. I., Vil'ner, B. Y., & Zavadskaya, T. V. (1992) · Neuroscience · doi:10.1016/0306-4522(92)90194-7 · Cited by 3
Research works printed but not linked: 5
- Davies AM, 1990, J. Physiol., 84, 100
- Johnson JE, 1997, Soc. Neurosci. Abstr., 23, 882
- Levi-Montalcini R, 1954, Cancer Res., 14, 49
- Menesini Chen MG, 1978, Arch. Ital. Biol., 116, 53
- Purves D, 1988, Body and Brain.
Cited by
Sorted by citations
Shrestha, S., & Offer, S. M. (2016) · Medical Epigenetics · doi:10.1159/000444713 · Cited by 8,951
Neurotrophins: Roles in Neuronal Development and Function
Huang, E. J., & Reichardt, L. F. (2001) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.24.1.677 · Cited by 4,394
Exercise: a behavioral intervention to enhance brain health and plasticity
Cotman, C. (2002) · Trends in Neurosciences · doi:10.1016/s0166-2236(02)02143-4 · Cited by 2,739
Neurotrophins and their receptors: A convergence point for many signalling pathways
Chao, M. V. (2003) · Nature Reviews Neuroscience · doi:10.1038/nrn1078 · Cited by 2,298
A brain-specific microRNA regulates dendritic spine development
Schratt, G. M., Tuebing, F., Nigh, E. A., Kane, C. G., Sabatini, M. E., Kiebler, M., & Greenberg, M. E. (2006) · Nature · doi:10.1038/nature04367 · Cited by 1,786
Metadata
- Authors
- McAllister, A. K., Katz, L. C., & Lo, D. C.
- Affiliations
- Salk Institute for Biological Studies (US)
- Howard Hughes Medical Institute (US)
- Venue
- Annual Review of Neuroscience
- Publisher
- Annual Reviews
- Published
- 1999-03
- Volume
- 22
- Issue
- 1
- Pages
- 295-318
- ISSN
- 0147-006X (ISSN-L)
- 1545-4126
- OpenAlex
- W2163639252
- Cited by
- 1,337
- References
- 228
- Citations by year
- 2026: 8 · 2025: 12 · 2024: 15 · 2023: 24 · 2022: 18 · 2021: 26 · 2020: 21 · 2019: 28 · 2018: 33 · 2017: 35 · 2016: 49 · 2015: 44 · 2014: 53 · 2013: 51 · 2012: 52
- FWCI
- 9.55
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Annual Review of Neuroscience (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Nerve injury and regeneration
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Life Sciences › Neuroscience › Developmental Neuroscience › Neurogenesis and neuroplasticity mechanisms
- Keywords
- neurotrophins, synaptic plasticity, activity-dependent plasticity, neurotrophin receptors, neuronal growth, synaptic transmission, morphological plasticity
- MeSH terms
- Animals, Central Nervous System, Nerve Growth Factors, Neuronal Plasticity, Synapses, Receptors, Nerve Growth Factor
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
