The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Cardiac Actions of Angiotensin II: Role of an Intracardiac Renin-Angiotensin System
Abstract
The renin-angiotensin system has a varied role in the regulation of cardiac function, ranging from early receptor-mediated effects such as second messenger generation, to more delayed responses such as protein synthesis and cell growth. Clinically, the importance of the RAS in cardiovascular disease is becoming increasingly evident with the use of ACE inhibitors in treating various pathological processes. With evidence for the existence of a local RAS in the heart, the molecular and biochemical regulation of this system requires investigation. Much additional work needs to be directed toward elucidating the mechanisms by which the AII-receptor couples to cardiac growth, how the local RAS is regulated, and the nature of controls that modulate cardiac production and actions of this peptide. Increased understanding of the mechanisms by which AII actions are affected in cardiac tissue will likely lead to enhanced therapeutic modalities for the treatment of pathological cardiovascular conditions in which the RAS plays an integral role.
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Citations
Cites
Positive chronotropic and inotropic effects of angiotension II in the dog heart
Kobayashi, M., Furukawa, Y., & Chiba, S. (1978) · European Journal of Pharmacology · doi:10.1016/0014-2999(78)90249-2 · Cited by 132
Cited by
Angiotensin II cell signaling: physiological and pathological effects in the cardiovascular system
Mehta, P. K., & Griendling, K. K. (2007) · American Journal of Physiology-Cell Physiology · doi:10.1152/ajpcell.00287.2006 · Cited by 1,924
Sadoshima, J.-I., Xu, Y., Slayter, H. S., & Izumo, S. (1993) · Cell · doi:10.1016/0092-8674(93)90541-w · Cited by 1,348
Diep, Q. (2004) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2003.11.004 · Cited by 165
p53 Induces Myocyte Apoptosis via the Activation of the Renin–Angiotensin System
Pierzchalski, P., Reiss, K., Cheng, W., Cirielli, C., Kajstura, J., Nitahara, J. A., Rizk, M., Capogrossi, M. C., & Anversa, P. (1997) · Experimental Cell Research · doi:10.1006/excr.1997.3604 · Cited by 135
Martino, T. A., Tata, N., Simpson, J. A., Vanderlaan, R., Dawood, F., Kabir, M. G., Khaper, N., Cifelli, C., Podobed, P., Liu, P. P., et al. (2011) · Journal of the American College of Cardiology · doi:10.1016/j.jacc.2010.11.022 · Cited by 94
Metadata
- Authors
- Baker, K. M., Booz, G. W., & Dostal, D. E.
- Venue
- Annual Review of Physiology
- Publisher
- Annual Reviews
- Published
- 1992-10
- Volume
- 54
- Issue
- 1
- Pages
- 227-241
- ISSN
- 0066-4278 (ISSN-L)
- 1545-1585
- OpenAlex
- W2108915868
- Cited by
- 517
- References
- 1
- FWCI
- 25.08
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Cardiac Actions of Angiotensin II: Role of an Intracardiac Renin-Angiotensin System. https://app.cochat.ai/papers/10.1146/annurev.ph.54.030192.001303
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- Baker, K. M., Booz, G. W., & Dostal, D. E. (1992). Cardiac Actions of Angiotensin II: Role of an Intracardiac Renin-Angiotensin System. Annual Review of Physiology. https://doi.org/10.1146/annurev.ph.54.030192.001303
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.