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M OLECULAR T HEORY OF H YDROPHOBIC E FFECTS: “She is too mean to have her name repeated.”
Open accessAbstract
▪ Abstract This paper reviews the molecular theory of hydrophobic effects relevant to biomolecular structure and assembly in aqueous solution. Recent progress has resulted in simple, validated molecular statistical thermodynamic theories and clarification of confusing theories of decades ago. Current work is resolving effects of wider variations of thermodynamic state, e.g., pressure denaturation of soluble proteins, and more exotic questions such as effects of surface chemistry in treating stability of macromolecular structures in aqueous solution.
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Cited by
Hydrophobic hydration from small to large lengthscales: Understanding and manipulating the crossover
Rajamani, S., Truskett, T. M., & Garde, S. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0504089102 · Cited by 300
Critical Importance of Length-Scale Dependence in Implicit Modeling of Hydrophobic Interactions
Chen, J., & Brooks, C. L. (2007) · Journal of the American Chemical Society · doi:10.1021/ja068383+ · Cited by 47
Automated simulation-based membrane protein refinement into cryo-EM data
Yvonnesdotter, L., Rovšnik, U., Blau, C., Lycksell, M., Howard, R. J., & Lindahl, E. (2023) · Biophysical Journal · doi:10.1016/j.bpj.2023.05.033 · Cited by 6
Metadata
- Authors
- Pratt, L. R.
- Venue
- Annual Review of Physical Chemistry
- Publisher
- Annual Reviews
- Published
- 2002-10
- Volume
- 53
- Issue
- 1
- Pages
- 409-436
- ISSN
- 0066-426X (ISSN-L)
- 1545-1593
- OpenAlex
- W1948756557
- Cited by
- 305
- References
- 0
- FWCI
- 0.88
- Type
- journal article
- Language
- en
- Open access
- green
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- CoChat. (2026). Citation check: M OLECULAR T HEORY OF H YDROPHOBIC E FFECTS: “She is too mean to have her name repeated.”. https://app.cochat.ai/papers/10.1146/annurev.physchem.53.090401.093500
- The paper
- Pratt, L. R. (2002). M OLECULAR T HEORY OF H YDROPHOBIC E FFECTS: “She is too mean to have her name repeated.”. Annual Review of Physical Chemistry. https://doi.org/10.1146/annurev.physchem.53.090401.093500
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.