The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
ORGANIC CATION TRANSPORTERS IN INTESTINE, KIDNEY, LIVER, AND BRAIN
Abstract
▪ Abstract This review focuses on sodium-independent transport systems for organic cations in small intestine, liver, kidney, and brain. The roles of P-glycoproteins (MDR) and anion transporters (OATP) in organic cation transport are reported, and two members of the new transporter family OCT are described. The OCT transporters belong to a superfamily that includes multidrug-resistance proteins, facilitative diffusion systems, and proton antiporters. They mediate electrogenic transport of small organic cations with different molecular structures, independently of sodium and proton gradients. The current knowledge of the distribution and functional properties of cloned cation transport systems and of cation transport measured in intact plasma membranes is used to postulate identical or homologous transporters in intestine, liver, kidney, and brain.
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Citations
Cites
Molecular Physiology of Norepinephrine and Serotonin Transporters
Blakely, R. D., De Felice, L. J., & Hartzell, H. C. (1994) · Journal of Experimental Biology · doi:10.1242/jeb.196.1.263 · Cited by 404
Cited by
Pao, S. S., Paulsen, I. T., & Saier, M. H. (1998) · Microbiology and Molecular Biology Reviews · doi:10.1128/mmbr.62.1.1-34.1998 · Cited by 2,297
Molecular identification of a renal urate–anion exchanger that regulates blood urate levels
Enomoto, A., Kimura, H., Chairoungdua, A., Shigeta, Y., Jutabha, P., Ho Cha, S., Hosoyamada, M., Takeda, M., Sekine, T., Igarashi, T., et al. (2002) · Nature · doi:10.1038/nature742 · Cited by 1,535
Koepsell, H., Lips, K., & Volk, C. (2007) · Pharmaceutical Research · doi:10.1007/s11095-007-9254-z · Cited by 988
Self-citationImpact of Drug Transporter Studies on Drug Discovery and Development
Mizuno, N., Niwa, T., Yotsumoto, Y., & Sugiyama, Y. (2003) · Pharmacological Reviews · doi:10.1124/pr.55.3.1 · Cited by 490
Intranasal drug delivery: An efficient and non-invasive route for systemic administration
Grassin-Delyle, S., Buenestado, A., Naline, E., Faisy, C., Blouquit-Laye, S., Couderc, L.-J., Le Guen, M., Fischler, M., & Devillier, P. (2012) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2012.03.003 · Cited by 398
Metadata
- Authors
- Koepsell, H.
- Venue
- Annual Review of Physiology
- Publisher
- Annual Reviews
- Published
- 1998-10
- Volume
- 60
- Issue
- 1
- Pages
- 243-266
- ISSN
- 0066-4278 (ISSN-L)
- 1545-1585
- OpenAlex
- W2104587909
- Cited by
- 310
- References
- 1
- FWCI
- 1.75
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: ORGANIC CATION TRANSPORTERS IN INTESTINE, KIDNEY, LIVER, AND BRAIN. https://app.cochat.ai/papers/10.1146/annurev.physiol.60.1.243
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- Koepsell, H. (1998). ORGANIC CATION TRANSPORTERS IN INTESTINE, KIDNEY, LIVER, AND BRAIN. Annual Review of Physiology. https://doi.org/10.1146/annurev.physiol.60.1.243
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
