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Cited by 285

The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.

Polarized Calcium Signaling in Exocrine Gland Cells

Petersen, Ole H., Tepikin, Alexei V.·2008·Annual Review of Physiology

Abstract

Cytosolic Ca 2+ signals are crucial for the control of fluid and enzyme secretion from exocrine glands. The highly polarized exocrine acinar cells have evolved sophisticated and complex Ca 2+ signaling mechanisms that exercise precise control of the secretory events occurring across the apical plasma membrane bordering the gland lumen. Ca 2+ stores in the endoplasmic reticulum, the secretory granules, the lysosomes, and the endosomes all play important roles in the generation of the local apical Ca 2+ spikes that switch on Cl− channels in the apical plasma membrane as well as exocytotic export of enzymes. The mitochondria are crucial not only for ATP generation but also for the physiologically important subcellular compartmentalization of the cytosolic Ca 2+ signals.

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Crossref · 10.1146/annurev.physiol.70.113006.100618

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Metadata

Authors
Petersen, O. H., & Tepikin, A. V.
Venue
Annual Review of Physiology
Published
2008-03-01
Volume
70
Issue
1
Pages
273-299
ISSN
  • 0066-4278 (ISSN-L)
  • 1545-1585
OpenAlex
W2105431222
Cited by
285
References
3
FWCI
0.61
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Polarized Calcium Signaling in Exocrine Gland Cells. https://app.cochat.ai/papers/10.1146/annurev.physiol.70.113006.100618
The paper
Petersen, O. H., & Tepikin, A. V. (2008). Polarized Calcium Signaling in Exocrine Gland Cells. Annual Review of Physiology. https://doi.org/10.1146/annurev.physiol.70.113006.100618

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.