The DOI matches its Crossref record; 172 of the 172 references it cites were found in a registry or an index.
Elicitors, Effectors, and R Genes: The New Paradigm and a Lifetime Supply of Questions
Abstract
The plant basal immune system can detect broadly present microbe-associated molecular patterns (MAMPs, also called PAMPs) and induce defenses, but adapted microbes express a suite of effector proteins that often act to suppress these defenses. Plants have evolved other receptors (R proteins) that detect these pathogen effectors and activate strong defenses. Pathogens can subsequently alter or delete their recognized effectors to avoid defense elicitation, at risk of a fitness cost associated with loss of those effectors. Significant research progress is revealing, among other things, mechanisms of MAMP perception, the host defense processes and specific host proteins that pathogen effectors target, the mechanisms of R protein activation, and the ways in which pathogen effector suites and R genes evolve. These findings carry practical ramifications for resistance durability and for future resistance engineering. The present review uses numerous questions to help clarify what we know and to identify areas that are ripe for further investigation.
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1 retracted
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The Genome of Black Cottonwood, Populus trichocarpa (Torr. & Gray)
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Significance of Inducible Defense-related Proteins in Infected Plants
van Loon, L. C., Rep, M., & Pieterse, C. M. J. (2006) · Annual Review of Phytopathology · doi:10.1146/annurev.phyto.44.070505.143425 · Cited by 3,410
Host-Microbe Interactions: Shaping the Evolution of the Plant Immune Response
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A Receptor Kinase-Like Protein Encoded by the Rice Disease Resistance Gene, Xa21
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Cited by
Boller, T., & Felix, G. (2009) · Annual Review of Plant Biology · doi:10.1146/annurev.arplant.57.032905.105346 · Cited by 3,387
Structure and functions of the bacterial microbiota of plants
Bulgarelli, D., Schlaeppi, K., Spaepen, S., van Themaat, E. V. L., & Schulze-Lefert, P. (2013) · Annual Review of Plant Biology · doi:10.1146/annurev-arplant-050312-120106 · Cited by 3,308
The Inflammasomes: Guardians of the Body
Martinon, F., Mayor, A., & Tschopp, J. (2009) · Annual Review of Immunology · doi:10.1146/annurev.immunol.021908.132715 · Cited by 2,436
Lu, D., Wu, S., Gao, X., Zhang, Y., Shan, L., & He, P. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0909705107 · Cited by 854
Wan, J., Tanaka, K., Zhang, X.-C., Son, G. H., Brechenmacher, L., Nguyen, T. H. N., & Stacey, G. (2012) · Plant Physiology · doi:10.1104/pp.112.201699 · Cited by 305
Metadata
- Authors
- Bent, A. F., & Mackey, D.
- Venue
- Annual Review of Phytopathology
- Publisher
- Annual Reviews
- Published
- 2007-09-08
- Volume
- 45
- Issue
- 1
- Pages
- 399-436
- ISSN
- 0066-4286 (ISSN-L)
- 1545-2107
- OpenAlex
- W2117534309
- Cited by
- 773
- References
- 172
- FWCI
- 4.99
- Type
- journal article
- Language
- en
- Open access
- closed
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- Bent, A. F., & Mackey, D. (2007). Elicitors, Effectors, and R Genes: The New Paradigm and a Lifetime Supply of Questions. Annual Review of Phytopathology. https://doi.org/10.1146/annurev.phyto.45.062806.094427
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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