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Receiver Operating Characteristic Curves and Their Use in Radiology
Abstract
Sensitivity and specificity are the basic measures of accuracy of a diagnostic test; however, they depend on the cut point used to define "positive" and "negative" test results. As the cut point shifts, sensitivity and specificity shift. The receiver operating characteristic (ROC) curve is a plot of the sensitivity of a test versus its false-positive rate for all possible cut points. The advantages of the ROC curve as a means of defining the accuracy of a test, construction of the ROC, and identification of the optimal cut point on the ROC curve are discussed. Several summary measures of the accuracy of a test, including the commonly used percentage of correct diagnoses and area under the ROC curve, are described and compared. Two examples of ROC curve application in radiologic research are presented.
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DeLong, E. R., DeLong, D. M., & Clarke-Pearson, D. L. (1988) · Biometrics · doi:10.2307/2531595 · Cited by 22,649
Cited by
Assessing the Performance of Prediction Models: A Framework for Traditional and Novel Measures
Steyerberg, E. W., Vickers, A. J., Cook, N. R., Gerds, T., Gonen, M., Obuchowski, N., Pencina, M. J., & Kattan, M. W. (2010) · Epidemiology · doi:10.1097/ede.0b013e3181c30fb2 · Cited by 5,170
Self-citationAhuja, C. S., Wilson, J. R., Nori, S., Kotter, M. R. N., Druschel, C., Curt, A., & Fehlings, M. G. (2017) · Nature Reviews Disease Primers · doi:10.1038/nrdp.2017.18 · Cited by 2,441
Use and Misuse of the Receiver Operating Characteristic Curve in Risk Prediction
Cook, N. R. (2007) · Circulation · doi:10.1161/circulationaha.106.672402 · Cited by 2,112
(2013) · Europe PMC (PubMed Central) · Cited by 2,089
Lakhani, P., & Sundaram, B. (2017) · Radiology · doi:10.1148/radiol.2017162326 · Cited by 1,775
Metadata
- Authors
- Obuchowski, N. A.
- Venue
- Radiology
- Published
- 2003-10
- Volume
- 229
- Issue
- 1
- Pages
- 3-8
- ISSN
- 0033-8419 (ISSN-L)
- 1527-1315
- OpenAlex
- W2124537635
- Cited by
- 843
- References
- 1
- FWCI
- 14.74
- Type
- journal article
- Language
- en
- Open access
- closed
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