The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.
Cerebral Perfusion CT: Technique and Clinical Applications
Abstract
Perfusion computed tomography (CT) is a relatively new technique that allows rapid qualitative and quantitative evaluation of cerebral perfusion by generating maps of cerebral blood flow (CBF), cerebral blood volume (CBV), and mean transit time (MTT). The technique is based on the central volume principle (CBF = CBV/MTT) and requires the use of commercially available software employing complex deconvolution algorithms to produce the perfusion maps. Some controversies exist regarding this technique, including which artery to use as input vessel, the accuracy of quantitative results, and the reproducibility of results. Despite these controversies, perfusion CT has been found to be useful for noninvasive diagnosis of cerebral ischemia and infarction and for evaluation of vasospasm after subarachnoid hemorrhage. Perfusion CT has also been used for assessment of cerebrovascular reserve by using acetazolamide challenge in patients with intracranial vascular stenoses who are potential candidates for bypass surgery or neuroendovascular treatment, for the evaluation of patients undergoing temporary balloon occlusion to assess collateral flow and cerebrovascular reserve, and for the assessment of microvascular permeability in patients with intracranial neoplasms. This article is a review of the technique, clinical applications, and controversies surrounding perfusion CT.
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Cites
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Cited by
Aneurysmal Subarachnoid Hemorrhage
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Multi-parametric neuroimaging reproducibility: A 3-T resource study
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Radiation dose reduction in perfusion CT imaging of the brain: A review of the literature
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Metadata
- Authors
- Hoeffner, E. G., Case, I., Jain, R., Gujar, S. K., Shah, G. V., Deveikis, J. P., Carlos, R. C., Thompson, B. G., Harrigan, M. R., & Mukherji, S. K.
- Venue
- Radiology
- Published
- 2004-06
- Volume
- 231
- Issue
- 3
- Pages
- 632-644
- ISSN
- 0033-8419 (ISSN-L)
- 1527-1315
- OpenAlex
- W2149677954
- Cited by
- 384
- References
- 28
- FWCI
- 18.71
- Type
- journal article
- Language
- en
- Open access
- closed
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- Hoeffner, E. G., Case, I., Jain, R., Gujar, S. K., Shah, G. V., Deveikis, J. P., Carlos, R. C., Thompson, B. G., Harrigan, M. R., & Mukherji, S. K. (2004). Cerebral Perfusion CT: Technique and Clinical Applications. Radiology. https://doi.org/10.1148/radiol.2313021488
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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