The DOI matches its Crossref record; 39 of the 39 references it cites were found in a registry or an index.
Radiation dose reduction in perfusion CT imaging of the brain: A review of the literature
Abstract
Perfusion CT (PCT) of the brain is widely used in the settings of acute ischemic stroke and vasospasm monitoring. The high radiation dose associated with PCT is a central topic and has been a focus of interest for many researchers. Many studies have examined the effect of radiation dose reduction in PCT using different approaches. Reduction of tube current and tube voltage can be efficient and lead to a remarkable reduction of effective radiation dose while preserving acceptable image quality. The use of novel noise reduction techniques such as iterative reconstruction or spatiotemporal smoothing can produce sufficient image quality from low-dose perfusion protocols. Reduction of sampling frequency of perfusion images has only little potential to reduce radiation dose. In the present article we aimed to summarize the available data on radiation dose reduction in PCT imaging of the brain.
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The amount of noise on an image is inversely proportional to the square root of the radiation dose.
“Based on the fact that the amount of noise on an image is inversely proportional to the square root of the radiation dose, reducing tube current and tube voltage can inevitably lead to the degradation of image quality, thereby generating a larger amount of noise on the image [30,31].”
From A Novel Singular Value Decomposition-Based Denoising Method in 4-Dimensional Computed Tomography of the Brain in Stroke Patients with Statistical Evaluation (2020) · cites this paper as [30]
Reducing tube current and tube voltage can inevitably lead to the degradation of image quality, thereby generating a larger amount of noise on the image.
“Based on the fact that the amount of noise on an image is inversely proportional to the square root of the radiation dose, reducing tube current and tube voltage can inevitably lead to the degradation of image quality, thereby generating a larger amount of noise on the image [30,31].”
From A Novel Singular Value Decomposition-Based Denoising Method in 4-Dimensional Computed Tomography of the Brain in Stroke Patients with Statistical Evaluation (2020) · cites this paper as [30]
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Yang, W., Hong, J.-Y., Kim, J.-Y., Paik, S.-H., Lee, S. H., Park, J.-S., Lee, G., Kim, B. M., & Jung, Y.-J. (2020) · Sensors · doi:10.3390/s20113063 · Cited by 17
“Based on the fact that the amount of noise on an image is inversely proportional to the square root of the radiation dose, reducing tube current and tube voltage can inevitably lead to the degradation of image quality, thereby generating a larger amount of noise on the image [30,31].”
BackgroundRiederer, I., Zimmer, C., Pfeiffer, D., Wunderlich, S., Poppert, H., Rummeny, E. J., & Huber, A. (2018) · Clinical Imaging · doi:10.1016/j.clinimag.2018.03.021 · Cited by 12
Metadata
- Authors
- Othman, A. E., Afat, S., Brockmann, M. A., Nikoubashman, O., Brockmann, C., Nikolaou, K., & Wiesmann, M.
- Affiliations
- University of Tübingen (DE)
- RWTH Aachen University (DE)
- Corresponding author
- Othman, Ahmed E.
- ORCID
- Venue
- Journal of Neuroradiology
- Publisher
- Elsevier BV
- Published
- 2016-02
- Volume
- 43
- Issue
- 1
- Pages
- 1-5
- ISSN
- 0150-9861 (ISSN-L)
- OpenAlex
- W2218813711
- Cited by
- 50
- References
- 39
- Citations by year
- 2026: 2 · 2025: 1 · 2024: 5 · 2023: 2 · 2022: 5 · 2021: 5 · 2020: 6 · 2019: 6 · 2018: 7 · 2017: 8 · 2016: 2
- FWCI
- 0.96
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Neuroradiology (publishedVersion)
- PubMed (publishedVersion)
- RWTH Publications (RWTH Aachen) (submittedVersion)
- Topics
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiation Dose and Imaging
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Advanced MRI Techniques and Applications
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Cardiac Imaging and Diagnostics
- Keywords
- CT perfusion, brain perfusion imaging, radiation dose reduction, tube current reduction, tube voltage reduction, iterative reconstruction, noise reduction, sampling frequency, acute ischemic stroke, effective dose
- MeSH terms
- Brain, Contrast Media, Humans, Image Processing, Computer-Assisted, Radiation Dosage, Radiographic Image Interpretation, Computer-Assisted, Tomography, X-Ray Computed, Perfusion Imaging
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