The DOI matches its Crossref record; 14 of the 14 references it cites were found in a registry or an index.
Microwave Ablation of Lung Malignancies: Effectiveness, CT Findings, and Safety in 50 Patients
Abstract
PURPOSE: To retrospectively evaluate effectiveness, follow-up imaging features, and safety of microwave ablation in 50 patients with intraparenchymal pulmonary malignancies. MATERIALS AND METHODS: This HIPAA-compliant study was approved by the institutional review board; informed consent was waived. From November 10, 2003, to August 28, 2006, 82 masses (mean, 1.42 per patient) in 50 patients (28 men, 22 women; mean age, 70 years) were percutaneously treated in 66 microwave ablation sessions. Each tumor was ablated with computed tomographic (CT) guidance. Follow-up contrast material-enhanced CT and positron emission tomographic (PET) scans were reviewed. Mixed linear modeling and logistic regression were performed. Time-event data were analyzed (Kaplan-Meier survival estimates and log-rank statistic). All event times were the time to a patient's first event (alpha level = .05, all analyses). RESULTS: At follow-up (mean, 10 months), 26% (13 of 50) of patients had residual disease at the ablation site, predicted by using index size of larger than 3 cm (P = .01). Another 22% (11 of 50) of patients had recurrent disease resulting in a 1-year local control rate of 67%, with mean time to first recurrence of 16.2 months. Kaplan-Meier analysis yielded an actuarial survival of 65% at 1 year, 55% at 2 years, and 45% at 3 years from ablation. Cancer-specific mortality yielded a 1-year survival of 83%, a 2-year survival of 73%, and a 3-year survival of 61%; these values were not significantly affected by index size of larger than 3 cm or 3 cm or smaller or presence of residual disease. Cavitation (43% [35 of 82] of treated tumors) was associated with reduced cancer-specific mortality (P = .02). Immediate complications included pneumothorax (Common Terminology Criteria for Adverse Events [CTCAE] grades 1 [18 of 66 patients] and 2 [eight of 66 patients]), hemoptysis (four of 66 patients), and skin burns (CTCAE grades 2 [one of 66 patients] and 3 [one of 66 patients]). CONCLUSION: Microwave ablation is effective and may be safely applied to lung tumors. (c) RSNA, 2008.
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Nonparametric Estimation from Incomplete Observations
Kaplan, E. L., & Meier, P. (1958) · Journal of the American Statistical Association · doi:10.1080/01621459.1958.10501452 · Cited by 39,158
Hepatocellular Carcinoma: Radio-frequency Ablation of Medium and Large Lesions
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Pulmonary Radiofrequency Ablation: Long-term Safety and Efficacy in 153 Patients
Simon, C. J., Dupuy, D. E., DiPetrillo, T. A., Safran, H. P., Grieco, C. A., Ng, T., & Mayo-Smith, W. W. (2007) · Radiology · doi:10.1148/radiol.2431060088 · Cited by 557
Self-citationIn Situ Tumor Ablation Creates an Antigen Source for the Generation of Antitumor Immunity
den Brok, M. H. M. G. M., Sutmuller, R. P. M., van der Voort, R., Bennink, E. J., Figdor, C. G., Ruers, T. J. M., & Adema, G. J. (2004) · Cancer Research · doi:10.1158/0008-5472.can-03-3949 · Cited by 426
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Image-guided Tumor Ablation: Standardization of Terminology and Reporting Criteria
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Cited by
Callister, M. E. J., Baldwin, D. R., Akram, A. R., Barnard, S., Cane, P., Draffan, J., Franks, K., Gleeson, F., Graham, R., Malhotra, P., et al. (2015) · Thorax · doi:10.1136/thoraxjnl-2015-207168 · Cited by 958
Principles of and Advances in Percutaneous Ablation
Ahmed, M., Brace, C. L., Lee, F. T., & Goldberg, S. N. (2011) · Radiology · doi:10.1148/radiol.10081634 · Cited by 916
Microwave Tumor Ablation: Mechanism of Action, Clinical Results, and Devices
Lubner, M. G., Brace, C. L., Hinshaw, J. L., & Lee, F. T. (2010) · Journal of Vascular and Interventional Radiology · doi:10.1016/j.jvir.2010.04.007 · Cited by 765
Rossmanna, C., & Haemmerich, D. (2014) · Critical Reviews in Biomedical Engineering · doi:10.1615/critrevbiomedeng.2015012486 · Cited by 370
Tumor Ablation: Common Modalities and General Practices
Knavel, E. M., & Brace, C. L. (2013) · Techniques in Vascular and Interventional Radiology · doi:10.1053/j.tvir.2013.08.002 · Cited by 368
Metadata
- Authors
- Wolf, F. J., Grand, D. J., Machan, J. T., DiPetrillo, T. A., Mayo-Smith, W. W., & Dupuy, D. E.
- Venue
- Radiology
- Published
- 2008-06
- Volume
- 247
- Issue
- 3
- Pages
- 871-879
- ISSN
- 0033-8419 (ISSN-L)
- 1527-1315
- OpenAlex
- W2117757695
- Cited by
- 398
- References
- 14
- FWCI
- 16.69
- Type
- journal article
- Language
- en
- Open access
- closed
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