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Work in progress: [18F] fluorodeoxyglucose and positron emission tomography in the evaluation of radiation necrosis of the brain.

Patronas, N J, Di Chiro, G, Brooks, R A, DeLaPaz, R L, Kornblith, P L, Smith, B H, Rizzoli, H V, Kessler, R M, Manning, R G, Channing, M, Wolf, A P, O'Connor, C M·1982·Radiology

Abstract

Five patients who had undergone radiation therapy for cerebral tumors and whose conditions were deteriorating were examined by means of positron emission tomography (PET) with [18F] fluorodeoxyglucose. All five cases had similar clinical and computed tomographic findings. Using the PET technique the two cases of radiation necrosis were distinguished from the three recurrent tumors. In the two cases of radiation necrosis the rate of glucose utilization in the lesion was markedly reduced compared with the normal brain parenchyma. In the recurrent gliomas, however, the glucose metabolic rate was elevated. All five diagnoses were confirmed by biopsy or autopsy.

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Metadata

Authors
Patronas, N. J., Di Chiro, G., Brooks, R. A., DeLaPaz, R. L., Kornblith, P. L., Smith, B. H., Rizzoli, H. V., Kessler, R. M., Manning, R. G., Channing, M., Wolf, A. P., & O'Connor, C. M.
Venue
Radiology
Published
1982-09
Volume
144
Issue
4
Pages
885-889
ISSN
  • 0033-8419 (ISSN-L)
  • 1527-1315
OpenAlex
W2063139320
Cited by
298
References
0
FWCI
5.67
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Work in progress: [18F] fluorodeoxyglucose and positron emission tomography in the evaluation of radiation necrosis of the brain. https://app.cochat.ai/papers/10.1148/radiology.144.4.6981123
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Patronas, N. J., Di Chiro, G., Brooks, R. A., DeLaPaz, R. L., Kornblith, P. L., Smith, B. H., Rizzoli, H. V., Kessler, R. M., Manning, R. G., Channing, M., Wolf, A. P., & O'Connor, C. M. (1982). Work in progress: [18F] fluorodeoxyglucose and positron emission tomography in the evaluation of radiation necrosis of the brain. Radiology. https://doi.org/10.1148/radiology.144.4.6981123

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