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Tissue characterization with T1, T2, and proton density values: results in 160 patients with brain tumors.

Just, M, Thelen, M·1988·Radiology

Abstract

A method by which the tissue parameters - T1, T2, and proton density - can be measured simultaneously was used in 160 patients with brain tumors to test the complete potential of magnetic resonance (MR) imaging for quantitative tissue characterization. MR tissue parameters of a wide variety of tumors, edema, white matter, and gray matter were determined. While normal brain tissues showed only small interindividual variations of tissue parameters, pathologic entities (tumor, edema) were characterized by wide ranges of T1, T2, and proton density values. The considerable overlapping of tissue parameters in different tumor entities, which were analyzed in a three-dimensional T1/T2/proton density space, indicates that a reliable diagnosis cannot be made on the basis of a quantitative evaluation of T1, T2, and proton density alone.

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Metadata

Authors
Just, M., & Thelen, M.
Venue
Radiology
Published
1988-12
Volume
169
Issue
3
Pages
779-785
ISSN
  • 0033-8419 (ISSN-L)
  • 1527-1315
OpenAlex
W2084598262
Cited by
176
References
0
FWCI
4.67
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Tissue characterization with T1, T2, and proton density values: results in 160 patients with brain tumors. https://app.cochat.ai/papers/10.1148/radiology.169.3.3187000
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Just, M., & Thelen, M. (1988). Tissue characterization with T1, T2, and proton density values: results in 160 patients with brain tumors. Radiology. https://doi.org/10.1148/radiology.169.3.3187000

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