The DOI matches its Crossref record.
Recurrence of colorectal tumors: PET evaluation.
Abstract
Positron emission tomography (PET) was used in the follow-up of patients with colorectal malignancies to differentiate between recurrent colorectal tumor and scar. Patients were examined with oxygen-15-labeled water and with fluorine-18-labeled deoxyglucose (FDG). FDG was injected intravenously to assess tumor metabolism. The tracer concentration was quantitatively evaluated by means of a region-of-interest technique and standardized for both injected dose and body volume. Of 29 patients, 21 had recurrent colorectal malignancy, and eight had a nonmalignant mass. All malignancies were seen on the PET cross sections. Nonmalignant lesions had a low FDG accumulation on images obtained 60 minutes after injection. While the tumor-soft tissue ratio was highest shortly after the intravenous injection of FDG, the tumor-scar ratio was highest 60 minutes after injection. It was possible to differentiate tumor from non-malignant tissue with FDG with the use of standardized concentration values and tumor-soft tissue ratios. Imaging with O-15-labeled water gave no additional information.
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Cited by
Sugawara, Y., Zasadny, K. R., Neuhoff, A. W., & Wahl, R. L. (1999) · Radiology · doi:10.1148/radiology.213.2.r99nv37521 · Cited by 265
Lai, D. T. M. (1996) · Archives of Surgery · doi:10.1001/archsurg.1996.01430190025007 · Cited by 254
PET and PET-CT for evaluation of colorectal carcinoma
Delbeke, D., & Martin, W. H. (2004) · Seminars in Nuclear Medicine · doi:10.1053/j.semnuclmed.2004.03.006 · Cited by 110
Metadata
- Authors
- Strauss, L. G., Clorius, J. H., Schlag, P., Lehner, B., Kimmig, B., Engenhart, R., Marin-Grez, M., Helus, F., Oberdorfer, F., & Schmidlin, P.
- Venue
- Radiology
- Published
- 1989-02
- Volume
- 170
- Issue
- 2
- Pages
- 329-332
- ISSN
- 0033-8419 (ISSN-L)
- 1527-1315
- OpenAlex
- W2091764247
- Cited by
- 268
- References
- 0
- FWCI
- 11.43
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Recurrence of colorectal tumors: PET evaluation. https://app.cochat.ai/papers/10.1148/radiology.170.2.2783494
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- Strauss, L. G., Clorius, J. H., Schlag, P., Lehner, B., Kimmig, B., Engenhart, R., Marin-Grez, M., Helus, F., Oberdorfer, F., & Schmidlin, P. (1989). Recurrence of colorectal tumors: PET evaluation. Radiology. https://doi.org/10.1148/radiology.170.2.2783494
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