The DOI matches its Crossref record; 1 of the 1 references it cites were found in a registry or an index.
Inflammation and Cancer V. Chronic pancreatitis and pancreatic cancer
Abstract
Pancreatic inflammation appears to increase the risk of pancreatic cancer. This observation is striking in the hereditary pancreatitis kindreds but also occurs in alcoholic, idiopathic, and tropical chronic pancreatitis and cystic fibrosis. However, the mutations associated with hereditary pancreatitis or cystic fibrosis are not found in sporadic pancreatic adenocarcinomas, suggesting that the effects are indirect by causing recurrent pancreatitis and chronic inflammation. The process of mutation accumulation and clonal expansion that is required for development of invasive pancreatic adenocarcinoma must therefore be accelerated in chronic pancreatitis to account for the high incidence of pancreatic cancer in these patients.
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Cites
BRCA2 germline mutations in familial pancreatic carcinoma
Hahn, S. A., Greenhalf, B., Ellis, I., Sina-Frey, M., Rieder, H., Korte, B., Gerdes, B., Kress, R., Ziegler, A., Raeburn, J. A., et al. (2003) · JNCI Journal of the National Cancer Institute · doi:10.1093/jnci/95.3.214 · Cited by 480
Cited by
Epidemiology of Pancreatic Cancer: Global Trends, Etiology and Risk Factors
Rawla, P., Sunkara, T., & Gaduputi, V. (2019) · World Journal of Oncology · doi:10.14740/wjon1166 · Cited by 2,269
Inflammation: Gearing the journey to cancer
KUNDU, J., & SURH, Y. (2008) · Mutation Research/Reviews in Mutation Research · doi:10.1016/j.mrrev.2008.03.002 · Cited by 803
Canto, M. I., Harinck, F., Hruban, R. H., Offerhaus, G. J., Poley, J.-W., Kamel, I., Nio, Y., Schulick, R. S., Bassi, C., Kluijt, I., et al. (2013) · Gut · doi:10.1136/gutjnl-2012-303108 · Cited by 784
“This PC risk is directly related to the duration of recurrent pancreatitis and chronic inflammation.(43) Screening of PRSS1 mutation carriers with longstanding chronic pancreatitis is being performed within established programmes(44) but it is controversial whether healthy siblings with a PRSS1 mutation should also be…”
BackgroundVariations of oral microbiota are associated with pancreatic diseases including pancreatic cancer
Farrell, J. J., Zhang, L., Zhou, H., Chia, D., Elashoff, D., Akin, D., Paster, B. J., Joshipura, K., & Wong, D. T. W. (2012) · Gut · doi:10.1136/gutjnl-2011-300784 · Cited by 662
Total Pancreatectomy and Islet Autotransplantation for Chronic Pancreatitis
Sutherland, D. E. R., Radosevich, D. M., Bellin, M. D., Hering, B. J., Beilman, G. J., Dunn, T. B., Chinnakotla, S., Vickers, S. M., Bland, B., Balamurugan, A. N., et al. (2012) · Journal of the American College of Surgeons · doi:10.1016/j.jamcollsurg.2011.12.040 · Cited by 461
Metadata
- Authors
- Whitcomb, D. C.
- Venue
- American Journal of Physiology-Gastrointestinal and Liver Physiology
- Publisher
- American Physiological Society
- Published
- 2004-08
- Volume
- 287
- Issue
- 2
- Pages
- G315-G319
- ISSN
- 0193-1857 (ISSN-L)
- 1522-1547
- OpenAlex
- W1988675408
- Cited by
- 202
- References
- 1
- FWCI
- 4.55
- Type
- journal article
- Language
- en
- Open access
- closed
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
