The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
A human colonic tumor cell line that maintains vectorial electrolyte transport
Abstract
A human colonic epithelial cell line, T84, derived from a colonic carcinoma, has been examined both morphologically and functionally. The cells grew to confluence as a monolayer with the basolateral membrane attached to the surface of the culture dish and a microvillus-studded apical membrane facing the media. Tight junctions and desmosomes were demonstrated between adjacent cells. Confluent monolayer cultures conducted vectorial electrolyte transport that could be altered by a variety of secretagogues and antisecretagogues similar to isolated intestinal tissues. This cell line will serve as an excellent model system for the study of electrolyte transport processes and their regulation by peptide hormones and neurotransmitters.
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Cites
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Self-citationIon transport in rabbit ileal mucosa. 3. Effects of catecholamines
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Electrolyte transport across isolated large intestinal mucosa
Binder, H., & Rawlins, C. (1973) · American Journal of Physiology-Legacy Content · doi:10.1152/ajplegacy.1973.225.5.1232 · Cited by 181
Active chloride secretion by rabbit colon: Calcium-dependent stimulation by ionophore A23187
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Effect of Conjugated Dihydroxy Bile Salts on Electrolyte Transport in Rat Colon
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Alteration of Large Intestinal Electrolyte Transport by Vasoactive Intestinal Polypeptide in the Rat
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Prostaglandins inhibit Intestinal Sodium Transport
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Identification of the Cystic Fibrosis Gene: Cloning and Characterization of Complementary DNA
Riordan, J. R., Rommens, J. M., Kerem, B.-S., Alon, N., Rozmahel, R., Grzelczak, Z., Zielenski, J., Lok, S., Plavsic, N., Chou, J.-L., et al. (1989) · Science · doi:10.1126/science.2475911 · Cited by 7,418
Identification of the Cystic Fibrosis Gene: Chromosome Walking and Jumping
Rommens, J. M., Iannuzzi, M. C., Kerem, B.-S., Drumm, M. L., Melmer, G., Dean, M., Rozmahel, R., Cole, J. L., Kennedy, D., Hidaka, N., et al. (1989) · Science · doi:10.1126/science.2772657 · Cited by 3,253
Inflammatory processes have differential effects on claudins 2, 3 and 4 in colonic epithelial cells
Prasad, S., Mingrino, R., Kaukinen, K., Hayes, K. L., Powell, R. M., MacDonald, T. T., & Collins, J. E. (2005) · Laboratory Investigation · doi:10.1038/labinvest.3700316 · Cited by 490
The human intestinal epithelial cell line Caco-2; pharmacological and pharmacokinetic applications
Meunier, V., Bourri�, M., Berger, Y., & Fabre, G. (1995) · Cell Biology and Toxicology · doi:10.1007/bf00756522 · Cited by 434
Melmed, G., Thomas, L. S., Lee, N., Tesfay, S. Y., Lukasek, K., Michelsen, K. S., Zhou, Y., Hu, B., Arditi, M., & Abreu, M. T. (2003) · The Journal of Immunology · doi:10.4049/jimmunol.170.3.1406 · Cited by 431
Metadata
- Authors
- Dharmsathaphorn, K., McRoberts, J. A., Mandel, K. G., Tisdale, L. D., & Masui, H.
- Venue
- American Journal of Physiology-Gastrointestinal and Liver Physiology
- Publisher
- American Physiological Society
- Published
- 1984-02-01
- Volume
- 246
- Issue
- 2
- Pages
- G204-G208
- ISSN
- 0193-1857 (ISSN-L)
- 1522-1547
- OpenAlex
- W2269095518
- Cited by
- 398
- References
- 9
- FWCI
- 3.01
- Type
- journal article
- Language
- en
- Open access
- closed
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- Dharmsathaphorn, K., McRoberts, J. A., Mandel, K. G., Tisdale, L. D., & Masui, H. (1984). A human colonic tumor cell line that maintains vectorial electrolyte transport. American Journal of Physiology-Gastrointestinal and Liver Physiology. https://doi.org/10.1152/ajpgi.1984.246.2.g204
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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