Effect of meal viscosity and nutrients on satiety, intragastric dilution, and emptying assessed by MRI
Abstract
The relationship between the intragastric distribution, dilution, and emptying of meals and satiety was studied using noninvasive magnetic resonance imaging techniques in 12 healthy subjects with four polysaccharide test meals of varying viscosity and nutrient content as follows: 1) low-viscosity nonnutrient, 2) low-viscosity nutrient, 3) high-viscosity nonnutrient, and 4) high-viscosity nutrient. Increasing the nutrient content of the high-viscosity meal delayed gastric emptying from 46 ± 9 to 76 ± 6 min ( P < 0.004), whereas increasing viscosity had a smaller effect. The volume of secretions within the stomach 60 min after ingestion was higher for the high-viscosity nutrient meal ( P < 0.04). A simple model to calculate the total volume of secretion added to the test meal is presented. Color-coded dilution map images showed the heterogeneous process of progressive gastric dilution of high-viscosity meals, whereas low-viscosity meals were uniformly diluted. Fullness was found to be linearly related to total gastric volumes for the nutrient meals ( R 2= 0.98) and logarithmically related for the nonnutrient meals ( R 2= 0.96). Fullness was higher for high- compared with low-viscosity meals ( P < 0.02), and with the nutrient meals this was associated with greater antral volumes ( P < 0.05).
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An increased viscosity can promote the feeling of satiety.
“An increased viscosity can promote the feeling of satiety”
From Ultrasound-Assisted Extraction of Pectin from 'Saba' Banana Peel Waste: Optimization and Rheology Study (2022) · cites this paper as [36]
The addition of ultrasound-extracted pectin to orange juice could increase the level of fullness during meals.
“the addition of UEP could increase the level of fullness during meals.”
From Ultrasound-Assisted Extraction of Pectin from 'Saba' Banana Peel Waste: Optimization and Rheology Study (2022) · cites this paper as [36]
The viscosity of food correlates with satiety, with fullness during a meal being higher for highly viscous food.
“A study correlating the viscosity of food with satiety suggested that fullness during a meal is higher for highly viscous food [36].”
From Ultrasound-Assisted Extraction of Pectin from 'Saba' Banana Peel Waste: Optimization and Rheology Study (2022) · cites this paper as [36]
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- Authors
- Marciani, L., Gowland, P. A., Spiller, R. C., Manoj, P., Moore, R. J., Young, P., & Fillery-Travis, A. J.
- Affiliations
- University of Nottingham (GB)
- Division of Gastroenterology, Queen's Medical Centre, University Hospital, Nottingham NG7 2UH; and
- Quadram Institute (GB)
- Institute of Food Research, Colney, Norwich NR4 7UA, United Kingdom
- Venue
- American Journal of Physiology-Gastrointestinal and Liver Physiology
- Publisher
- American Physiological Society
- Published
- 2001-06-01
- Volume
- 280
- Issue
- 6
- Pages
- G1227-G1233
- ISSN
- 0193-1857 (ISSN-L)
- 1522-1547
- OpenAlex
- W2128249820
- Cited by
- 502
- References
- 0
- Citations by year
- 2026: 14 · 2025: 12 · 2024: 11 · 2023: 22 · 2022: 20 · 2021: 33 · 2020: 27 · 2019: 35 · 2018: 27 · 2017: 29 · 2016: 26 · 2015: 24 · 2014: 28 · 2013: 34 · 2012: 35
- FWCI
- 5.12
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Physiology-Gastrointestinal and Liver Physiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Gastroenterology › Gastrointestinal motility and disorders
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Health Sciences › Nursing › Nutrition and Dietetics › Food composition and properties
- Keywords
- satiety, gastric emptying, gastric secretion, nutrient content
- MeSH terms
- Adult, Female, Food, Gastric Emptying, Gastric Mucosa, Humans, Magnetic Resonance Imaging, Male, Nutritional Physiological Phenomena, Satiety Response, Viscosity
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