Can dynamic in vitro digestion systems mimic the physiological reality?

High-protein, reduced-carbohydrate weight-loss diets promote metabolite profiles likely to be detrimental to colonic health

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A Multicompartmental Dynamic Computer-controlled Model Simulating the Stomach and Small Intestine

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Development of a 5-step multi-chamber reactor as a simulation of the human intestinal microbial ecosystem

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Butyrate-producingClostridiumcluster XIVa species specifically colonize mucins in anin vitrogut model

den Abbeele, P. V., Belzer, C., Goossens, M., Kleerebezem, M., de Vos, W. M., Thas, O., Weirdt, R. D., Kerckhof, F., & de Wiele, T. V. (2012) · The ISME Journal · doi:10.1038/ismej.2012.158 · Cited by 639 · see citing works

Disintegration of solid foods in human stomach.

Kong, F., & Singh, R. (2008) · Journal of Food Science · doi:10.1111/j.1750-3841.2008.00766.x · Cited by 610 · see citing works

Relevance and challenges in modeling human gastric and small intestinal digestion

Guerra, A., Etienne‐Mesmin, L., Livrelli, V., Denis, S., Blanquet‐Diot, S., & Alric, M. (2012) · Trends in biotechnology · doi:10.1016/j.tibtech.2012.08.001 · Cited by 569 · see citing works

Analysis of Gastric Emptying Data

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Effect of meal viscosity and nutrients on satiety, intragastric dilution, and emptying assessed by MRI

Marciani, L., Gowland, P. A., Spiller, R. C., Manoj, P., Moore, R. J., Young, P., & Fillery-Travis, A. J. (2001) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.2001.280.6.g1227 · Cited by 502 · see citing works

Survival of Lactic Acid Bacteria in a Dynamic Model of the Stomach and Small Intestine: Validation and the Effects of Bile

Marteau, P., Minekus, M., Havenaar, R., & Huis In’t Veld, J. H. J. (1997) · Journal of Dairy Science · doi:10.3168/jds.s0022-0302(97)76027-2 · Cited by 488 · see citing works

A computer-controlled system to simulate conditions of the large intestine with peristaltic mixing, water absorption and absorption of fermentation products

Minekus, M., Smeets-Peeters, M. J. E., Bernalier, A., Marol-Bonnin, S., Havenaar, R., Marteau, P. R., Alric, M., Fonty, G., & Veld, J. H. J. H. I. (1999) · Applied Microbiology and Biotechnology · doi:10.1007/s002530051622 · Cited by 459 · see citing works

A Human Gastric Simulator (HGS) to Study Food Digestion in Human Stomach

Kong, F., & Singh, R. P. (2010) · Journal of Food Science · doi:10.1111/j.1750-3841.2010.01856.x · Cited by 428 · see citing works

Biphasic nature of gastric emptying.

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Microbial Community Development in a Dynamic Gut Model Is Reproducible, Colon Region Specific, and Selective forBacteroidetesandClostridiumCluster IX

den Abbeele, P. V., Grootaert, C., Marzorati, M., Possemiers, S., Verstraete, W., Gérard, P., Rabot, S., Bruneau, A., Aidy, S. E., Derrien, M., et al. (2010) · Applied and Environmental Microbiology · doi:10.1128/aem.00759-10 · Cited by 346 · see citing works

Modeling the Fluid Dynamics in a Human Stomach to Gain Insight of Food Digestion

Ferrua, M. J., & Singh, R. P. (2010) · Journal of Food Science · doi:10.1111/j.1750-3841.2010.01748.x · Cited by 294 · see citing works

Incorporating a mucosal environment in a dynamic gut model results in a more representative colonization by lactobacilli

den Abbeele, P. V., Roos, S., Eeckhaut, V., MacKenzie, D. A., Derde, M., Verstraete, W., Marzorati, M., Possemiers, S., Vanhoecke, B. W. A., Immerseel, F. V., et al. (2011) · Microbial Biotechnology · doi:10.1111/j.1751-7915.2011.00308.x · Cited by 291 · see citing works

PCR-DGGE-based quantification of stability of the microbial community in a simulator of the human intestinal microbial ecosystem

Possemiers, S., Verthé, K., Uyttendaele, S., & Verstraete, W. (2004) · FEMS Microbiology Ecology · doi:10.1016/j.femsec.2004.05.002 · Cited by 259 · see citing works

The Prenylflavonoid Isoxanthohumol from Hops (Humulus lupulus L.) Is Activated into the Potent Phytoestrogen 8-Prenylnaringenin In Vitro and in the Human Intestine

Possemiers, S., Bolca, S., Grootaert, C., Heyerick, A., Decroos, K., Dhooge, W., Keukeleire, D. D., Rabot, S., Verstraete, W., & de Wiele, T. V. (2006) · Journal of Nutrition · doi:10.1093/jn/136.7.1862 · Cited by 258 · see citing works

Arabinoxylans and inulin differentially modulate the mucosal and luminal gut microbiota and mucin‐degradation in humanized rats

den Abbeele, P. V., Gérard, P., Rabot, S., Bruneau, A., Aidy, S. E., Derrien, M., Kleerebezem, M., Zoetendal, E. G., Smidt, H., Verstraete, W., et al. (2011) · Environmental Microbiology · doi:10.1111/j.1462-2920.2011.02533.x · Cited by 257 · see citing works

Validation of a new in vitro dynamic system to simulate infant digestion

Ménard, O., Cattenoz, T., Guillemin, H., Souchon, I., Deglaire, A., Dupont, D., & Picque, D. (2013) · Food Chemistry · doi:10.1016/j.foodchem.2013.09.036 · Cited by 248 · see citing works

Validation of the Simulator of the Human Intestinal Microbial Ecosystem (SHIME) Reactor Using Microorganism-associated Activities

Molly, K., Woestyne, M. V., Smet, I. D., & Verstraete, W. (1994) · Microbial Ecology in Health and Disease · doi:10.3109/08910609409141354 · Cited by 241 · see citing works

Prebiotic effects of chicory inulin in the simulator of the human intestinal microbial ecosystem

de Wiele, T. V., Boon, N., Possemiers, S., Jacobs, H., & Verstraete, W. (2004) · FEMS Microbiology Ecology · doi:10.1016/j.femsec.2004.07.014 · Cited by 214 · see citing works

Assessment of antral grinding of a model solid meal with echo-planar imaging

Marciani, L., Gowland, P. A., Fillery‐Travis, A., et al. (2001) · American Journal of Physiology-Gastrointestinal and Liver Physiology · doi:10.1152/ajpgi.2001.280.5.g844 · Cited by 210 · see citing works

Bioprocessing of Wheat Bran in Whole Wheat Bread Increases the Bioavailability of Phenolic Acids in Men and Exerts Antiinflammatory Effects ex Vivo

Anson, N. M., Aura, A., Nordlund, E., Mattila, I. M., Poutanen, K. S., van den Berg, R., Havenaar, R., Bast, A., & Haenen, G. R. M. M. (2010) · Journal of Nutrition · doi:10.3945/jn.110.127720 · Cited by 208 · see citing works

The HMI™ module: a new tool to study the Host-Microbiota Interaction in the human gastrointestinal tract in vitro

Marzorati, M., Vanhoecke, B. W. A., Ryck, T. D., Sadabad, M. S., Pinheiro, I., Possemiers, S., den Abbeele, P. V., Derycke, L., Bracke, M., Pieters, J., et al. (2014) · BMC Microbiology · doi:10.1186/1471-2180-14-133 · Cited by 208 · see citing works

Comparison of five in vitro digestion models to in vivo experimental results: Lead bioaccessibility in the human gastrointestinal tract

de Wiele, T. V., Oomen, A. G., Wragg, J., et al. (2007) · Journal of Environmental Science and Health Part A · doi:10.1080/10934520701434919 · Cited by 191 · see citing works

Validation of the Simulator of the Human Intestinal Microbial Ecosystem (SHIME) Reactor Using Microorganism-associated Activities

Molly, K., Woestyne, M. V., & Smet, I. D. (1994) · Microbial Ecology in Health and Disease · doi:10.3402/mehd.v7i4.8295 · Cited by 190 · see citing works

Effects of a high fat meal matrix and protein complexation on the bioaccessibility of blueberry anthocyanins using the TNO gastrointestinal model (TIM-1)

Ribnicky, D., Roopchand, D. E., Oren, A., Grace, M. H., Poulev, A., Lila, M. A., Havenaar, R., & Raskin, I. (2013) · Food Chemistry · doi:10.1016/j.foodchem.2013.07.073 · Cited by 183 · see citing works

Of the Major Phenolic Acids Formed during Human Microbial Fermentation of Tea, Citrus, and Soy Flavonoid Supplements, Only 3,4-Dihydroxyphenylacetic Acid Has Antiproliferative Activity ,

Gao, K., Xu, A., Krul, C. A. M., Venema, K., Liu, Y., Niu, Y., Lu, J., Bensoussan, L., Seeram, N. P., Heber, D., et al. (2006) · Journal of Nutrition · doi:10.1093/jn/136.1.52 · Cited by 183 · see citing works

Cholesterol lowering in pigs through enhanced bacterial bile salt hydrolase activity

Smet, I. D., Boever, P. D., & Verstraete, W. (1998) · British Journal Of Nutrition · doi:10.1079/bjn19980030 · Cited by 182 · see citing works

Linking phylogenetic identities of bacteria to starch fermentation in an in vitro model of the large intestine by RNA‐based stable isotope probing

Kovatcheva‐Datchary, P., Egert, M., Maathuis, A. J. H., Rajilić-Stojanović, M. D., de Graaf, A. A., Smidt, H., de Vos, W. M., & Venema, K. (2008) · Environmental Microbiology · doi:10.1111/j.1462-2920.2008.01815.x · Cited by 174 · see citing works

Effect of gel structure on the gastric digestion of whey protein emulsion gels

Guo, Q. Q., Ye, A., Lad, M., Dalgleish, D. G., & Singh, H. (2014) · Soft Matter · doi:10.1039/c3sm52758a · Cited by 173 · see citing works

The Protein Digestibility-Corrected Amino Acid Score (PDCAAS)—A Concept for Describing Protein Quality in Foods and Food Ingredients: A Critical Review

Schaafsma, G. (2005) · Journal of AOAC International · doi:10.1093/jaoac/88.3.988 · Cited by 166 · see citing works

Effect of intragastric acid stability of fat emulsions on gastric emptying, plasma lipid profile and postprandial satiety

Marciani, L., Faulks, R. M., Wickham, M. S. J., Bush, D., Pick, B., Wright, J. W., Cox, E. F., Fillery‐Travis, A., Gowland, P. A., & Spiller, R. E. (2008) · British Journal Of Nutrition · doi:10.1017/s0007114508039986 · Cited by 164 · see citing works

Achieving Antral Grinding Forces in Biorelevant In Vitro Models: Comparing the USP Dissolution Apparatus II and the Dynamic Gastric Model with Human In Vivo Data

Vardakou, M., Mercuri, A., Barker, S. A., Craig, D. Q. M., Faulks, R. M., & Wickham, M. S. J. (2011) · AAPS PharmSciTech · doi:10.1208/s12249-011-9616-z · Cited by 162 · see citing works

To pool or not to pool? Impact of the use of individual and pooled fecal samples for in vitro fermentation studies

Aguirre, M., Ramiro‐Garcia, J., Koenen, M. E., & Venema, K. (2014) · Journal of Microbiological Methods · doi:10.1016/j.mimet.2014.08.022 · Cited by 147 · see citing works

The Design, Operation, and Application of a Dynamic Gastric Model

Wickham, M. J. S., Faulks, R. M., Mann, J., et al. (2012) · Dissolution Technologies · doi:10.14227/dt190312p15 · Cited by 135 · see citing works

A new approach to predict human intestinal absorption using porcine intestinal tissue and biorelevant matrices

Westerhout, J., van de Steeg, E., Grossouw, D., et al. (2014) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2014.07.003 · Cited by 132 · see citing works

A level A in vitro/in vivo correlation in fasted and fed states using different methods: Applied to solid immediate release oral dosage form

Souliman, S., Blanquet, S., Beyssac, E., & Cardot, J. (2005) · European Journal of Pharmaceutical Sciences · doi:10.1016/j.ejps.2005.08.006 · Cited by 128 · see citing works

Eubacterium limosum Activates Isoxanthohumol from Hops (Humulus lupulus L.) into the Potent Phytoestrogen 8-Prenylnaringenin In Vitro and in Rat Intestine3

Possemiers, S., Rabot, S., Espı́n, J. C., Bruneau, A., Philippe, C., González‐Sarrías, A., Heyerick, A., Tomás-Barberán, F. A., Keukeleire, D. D., & Verstraete, W. (2008) · Journal of Nutrition · doi:10.1093/jn/138.7.1310 · Cited by 120 · see citing works

Decreased colonization of fecal Clostridium coccoides/Eubacterium rectale species from ulcerative colitis patients in an in vitro dynamic gut model with mucin environment

Vermeiren, J., den Abbeele, P. V., Laukens, D., Vigsnæs, L. K., Vos, M. D., Boon, N., & de Wiele, T. V. (2011) · FEMS Microbiology Ecology · doi:10.1111/j.1574-6941.2011.01252.x · Cited by 120 · see citing works

Different Human Gut Models Reveal the Distinct Fermentation Patterns of Arabinoxylan versus Inulin

den Abbeele, P. V., Venema, K., de Wiele, T. V., Verstraete, W., & Possemiers, S. (2013) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf4021784 · Cited by 120 · see citing works

Evaluation of two dynamic in vitro models simulating fasted and fed state conditions in the upper gastrointestinal tract (TIM-1 and tiny-TIM) for investigating the bioaccessibility of pharmaceutical compounds from oral dosage forms

Verwei, M., Minekus, M., Zeijdner, E. E., et al. (2015) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2015.11.048 · Cited by 118 · see citing works

Development of an advanced in vitro model of the stomach and its evaluation versus human gastric physiology

Bellmann, S., Lelieveld, J., Gorissen, T., Minekus, M., & Havenaar, R. (2016) · Food Research International · doi:10.1016/j.foodres.2016.01.030 · Cited by 117 · see citing works

Antral motility measurements by magnetic resonance imaging

Marciani, L., Young, P. G., Wright, J. W., et al. (2001) · Neurogastroenterology & Motility · doi:10.1046/j.1365-2982.2001.00285.x · Cited by 114 · see citing works

Development of human colonic microbiota in the computer-controlled dynamic SIMulator of the GastroIntestinal tract SIMGI

Barroso, E., Cueva, C., Peláez, C., Martínez‐Cuesta, M. C., & Requena, T. (2014) · LWT · doi:10.1016/j.lwt.2014.12.014 · Cited by 113 · see citing works

Tracking the in vivo release of bioactive peptides in the gut during digestion: Mass spectrometry peptidomic characterization of effluents collected in the gut of dairy matrix fed mini-pigs

Barbé, F., Feunteun, S. L., Rémond, D., Ménard, O., Jardin, J., Henry, G., Laroche, B., & Dupont, D. (2014) · Food Research International · doi:10.1016/j.foodres.2014.02.015 · Cited by 113 · see citing works

Combining the Dynamic TNO-Gastrointestinal Tract System with a Caco-2 Cell Culture Model: Application to the Assessment of Lycopene and α-Tocopherol Bioavailability from a Whole Food

Déat, E., Blanquet‐Diot, S., Jarrige, J.-F., et al. (2009) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf902392a · Cited by 108 · see citing works

In Vitro Characterization of the Impact of Different Substrates on Metabolite Production, Energy Extraction and Composition of Gut Microbiota from Lean and Obese Subjects

Aguirre, M., Jonkers, D. M. A. E., Troost, F. J., Roeselers, G., & Venema, K. (2014) · PLoS ONE · doi:10.1371/journal.pone.0113864 · Cited by 108 · see citing works

Profiling of Microbial-Derived Phenolic Metabolites in Human Feces after Moderate Red Wine Intake

Muñoz‐González, I., Jiménez-Girón, A., Martín‐Álvarez, P. J., Bartolomé, B., & Moreno-Arribas, M. V. (2013) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf4025135 · Cited by 107 · see citing works

Holder pasteurization impacts the proteolysis, lipolysis and disintegration of human milk under in vitro dynamic term newborn digestion

de Oliveira, S. C., Deglaire, A., Ménard, O., Bellanger, A., Rousseau, F., Henry, G., Dirson, E., Carrière, F., Dupont, D., & Bourlieu‐Lacanal, C. (2015) · Food Research International · doi:10.1016/j.foodres.2015.11.022 · Cited by 100 · see citing works

Evaluating the microbial diversity of an in vitro model of the human large intestine by phylogenetic microarray analysis

Rajilić-Stojanović, M. D., Maathuis, A. J. H., Heilig, H. G. H. J., Venema, K., de Vos, W. M., & Smidt, H. (2010) · Microbiology · doi:10.1099/mic.0.042044-0 · Cited by 99 · see citing works

Assessment of the Multi-mycotoxin-Binding Efficacy of a Carbon/Aluminosilicate-Based Product in an in Vitro Gastrointestinal Model

Avantaggiato, G., Havenaar, R., & Visconti, A. (2007) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf0702803 · Cited by 97 · see citing works

Microbial and dietary factors associated with the 8-prenylnaringenin producer phenotype: a dietary intervention trial with fifty healthy post-menopausal Caucasian women

Bolca, S., Possemiers, S., Maervoet, V. E. T., Huybrechts, I., Heyerick, A., Vervarcke, S., Depypere, H. T., Keukeleire, D. D., Bracke, M., Henauw, S. D., et al. (2007) · British Journal Of Nutrition · doi:10.1017/s0007114507749243 · Cited by 95 · see citing works

Dynamic In Vitro Models of the Human Gastrointestinal Tract as Relevant Tools to Assess the Survival of Probiotic Strains and Their Interactions with Gut Microbiota

Cordonnier, C., Thévenot, J., Etienne‐Mesmin, L., Denis, S., Alric, M., Livrelli, V., & Blanquet‐Diot, S. (2015) · Microorganisms · doi:10.3390/microorganisms3040725 · Cited by 94 · see citing works

Estimation of the Bioavailability of Iron and Phosphorus in Cereals using a DynamicIn Vitro Gastrointestinal Model

Larsson, M., Minekus, M., & Havenaar, R. (1997) · Journal of the Science of Food and Agriculture · doi:10.1002/(sici)1097-0010(199705)74:1 · Cited by 94 · see citing works

Gastric emptying rate and chyme characteristics for cooked brown and white rice meals in vivo

Bornhorst, G. M., Chang, L. Q., Rutherfurd, S. M., Moughan, P. J., & Singh, R. P. (2013) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.6160 · Cited by 88 · see citing works

Impact of pasteurization of human milk on preterm newborn in vitro digestion: Gastrointestinal disintegration, lipolysis and proteolysis

de Oliveira, S. C., Bourlieu‐Lacanal, C., Ménard, O., et al. (2016) · Food Chemistry · doi:10.1016/j.foodchem.2016.05.028 · Cited by 88 · see citing works

In vitro gastrointestinal model (TIM) with predictive power, even for infants and children?

Havenaar, R., Anneveld, B., Hanff, L. M., et al. (2013) · International Journal of Pharmaceutics · doi:10.1016/j.ijpharm.2013.07.053 · Cited by 85 · see citing works

Evaluation of an optimal preparation of human standardized fecal inocula for in vitro fermentation studies

Aguirre, M., Eck, A., Koenen, M. E., Savelkoul, P. H. M., Budding, A. E., & Venema, K. (2015) · Journal of Microbiological Methods · doi:10.1016/j.mimet.2015.07.019 · Cited by 83 · see citing works

Digestion of cooked meat proteins is slightly affected by age as assessed using the dynamic gastrointestinal TIM model and mass spectrometry

Denis, S., Sayd, T., Georges, A. D. J., Chambon, C., Chalançon, S., Santé-Lhoutellier, V., & Blanquet‐Diot, S. (2016) · Food & Function · doi:10.1039/c6fo00120c · Cited by 83 · see citing works

Peptide mapping during dynamic gastric digestion of heated and unheated skimmed milk powder

Sánchez‐Rivera, L., Ménard, O., Recio, I., & Dupont, D. (2015) · Food Research International · doi:10.1016/j.foodres.2015.08.001 · Cited by 82 · see citing works

Starch-entrapped microspheres show a beneficial fermentation profile and decrease in potentially harmful bacteria during in vitro fermentation in faecal microbiota obtained from patients with inflammatory bowel disease

Rose, D. J., Venema, K., Keshavarzian, A., & Hamaker, B. R. (2009) · British Journal Of Nutrition · doi:10.1017/s0007114509993515 · Cited by 78 · see citing works

Gastric pH Distribution and Mixing of Soft and Rigid Food Particles in the Stomach using a Dual-Marker Technique

Bornhorst, G. M., Rutherfurd, S. M., Roman, M. J., et al. (2014) · Food Biophysics · doi:10.1007/s11483-014-9354-3 · Cited by 77 · see citing works

Use of Artificial Digestive Systems to Investigate the Biopharmaceutical Factors Influencing the Survival of Probiotic Yeast During Gastrointestinal Transit in Humans

Blanquet‐Diot, S., Denis, S., Chalançon, S., Chaira, F., Cardot, J., & Alric, M. (2011) · Pharmaceutical Research · doi:10.1007/s11095-011-0620-5 · Cited by 70 · see citing works

Application of a new Dynamic Gastrointestinal Simulator (SIMGI) to study the impact of red wine in colonic metabolism

Cueva, C., Jiménez-Girón, A., Muñoz‐González, I., et al. (2015) · Food Research International · doi:10.1016/j.foodres.2015.03.003 · Cited by 69 · see citing works

Development and validation of a new dynamic computer‐controlled model of the human stomach and small intestine

Guerra, A., Denis, S., le Goff, O., et al. (2015) · Biotechnology and Bioengineering · doi:10.1002/bit.25890 · Cited by 66 · see citing works

The Effect of Lactulose on the Composition of the Intestinal Microbiota and Short-chain Fatty Acid Production in Human Volunteers and a Computer-controlled Model of the Proximal Large Intestine

Venema, K., van Nuenen, M. H. M. C., van den Heuvel, E. G. H. M., et al. (2003) · Microbial Ecology in Health and Disease · doi:10.1080/08910600310019895 · Cited by 64 · see citing works

Antioxidant and anti-inflammatory capacity of bioaccessible compounds from wheat fractions after gastrointestinal digestion

Anson, N. M., Havenaar, R., Bast, A., et al. (2009) · Journal of Cereal Science · doi:10.1016/j.jcs.2009.10.005 · Cited by 60 · see citing works

D-Tagatose increases butyrate production by the colonic microbiota in healthy men and women

Venema, K., Vermunt, S. H. F., & Brink, E. J. (2005) · Microbial Ecology in Health and Disease · doi:10.1080/08910600510035093 · Cited by 59 · see citing works

Rheological Properties and Textural Attributes of Cooked Brown and White Rice During Gastric Digestion in Vivo

Bornhorst, G. M., Ferrua, M. J., Rutherfurd, S. M., Heldman, D. R., & Singh, R. P. (2013) · Food Biophysics · doi:10.1007/s11483-013-9288-1 · Cited by 58 · see citing works

Predicted Serum Folate Concentrations Based on In Vitro Studies and Kinetic Modeling are Consistent with Measured Folate Concentrations in Humans

Verwei, M., Freidig, A. P., Havenaar, R., et al. (2006) · Journal of Nutrition · doi:10.1093/jn/136.12.3074 · Cited by 58 · see citing works

Metabolite Production during in Vitro Colonic Fermentation of Dietary Fiber: Analysis and Comparison of Two European Diets

Tabernero, M., Venema, K., Maathuis, A. J. H., & Saura-Calixto, F. D. (2011) · Journal of Agricultural and Food Chemistry · doi:10.1021/jf201777w · Cited by 58 · see citing works

Investigation of the Biopharmaceutical Behavior of Theophylline Hydrophilic Matrix Tablets Using USP Methods and an Artificial Digestive System

Souliman, S., Beyssac, E., Cardot, J., et al. (2007) · Drug Development and Industrial Pharmacy · doi:10.1080/03639040601128654 · Cited by 57 · see citing works

Enterohemorrhagic Escherichia coli infection has donor-dependent effect on human gut microbiota and may be antagonized by probiotic yeast during interaction with Peyer’s patches

Thévenot, J., Cordonnier, C., Rougeron, A., Goff, O. L., Nguyen, H. T. T., Denis, S., Alric, M., Livrelli, V., & Blanquet‐Diot, S. (2015) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-015-6704-0 · Cited by 57 · see citing works

Microbiotas from UC patients display altered metabolism and reduced ability of LAB to colonize mucus

Vigsnæs, L. K., den Abbeele, P. V., Sulek, K., Frandsen, H. L., Steenholdt, C., Brynskov, J., Vermeiren, J., de Wiele, T. V., & Licht, T. R. (2013) · Scientific Reports · doi:10.1038/srep01110 · Cited by 53 · see citing works

Dynamic gastric digestion of a commercial whey protein concentrate†

Miralles, B., del Barrio, R., Cueva, C., et al. (2017) · Journal of the Science of Food and Agriculture · doi:10.1002/jsfa.8668 · Cited by 51 · see citing works

Herring roe protein has a high digestible indispensable amino acid score (DIAAS) using a dynamic in vitro gastrointestinal model

Havenaar, R., Maathuis, A. J. H., de Jong, A., Mancinelli, D., Berger, A., & Bellmann, S. (2016) · Nutrition Research · doi:10.1016/j.nutres.2016.05.004 · Cited by 47 · see citing works

Enterohemorrhagic Escherichia coli O157:H7 Survival in an In Vitro Model of the Human Large Intestine and Interactions with Probiotic Yeasts and Resident Microbiota

Thévenot, J., Etienne‐Mesmin, L., Denis, S., Chalançon, S., Alric, M., Livrelli, V., & Blanquet‐Diot, S. (2012) · Applied and Environmental Microbiology · doi:10.1128/aem.03303-12 · Cited by 46 · see citing works

The Journal of Science of Food and Agriculture

(2018) · The Journal of the Science of Food and Agriculture · doi:10.26855/jsfa · Cited by 45 · see citing works

Preparation and characterization of a packed bead immobilized trypsin reactor integrated into a PDMS microfluidic chip for rapid protein digestion

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