The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.
ROS and NO trigger early preconditioning: relationship to mitochondrial KATP channel
Abstract
Reactive oxygen species (ROS) and nitric oxide (NO) are implicated in induction of ischemic preconditioning. However, the relationship between these oxidant signals and opening of the mitochondrial ATP-dependent potassium (K ATP) channel during early preconditioning is not fully understood. We observed preconditioning protection by hypoxia, exogenous H 2 O 2, or PKC activator PMA in cardiomyocytes subjected to 1-h ischemia and 3-h reperfusion. Protection was abolished by K ATP channel blocker 5-hydroxydecanoate (5-HD) in each case, indicating that these triggers must act upstream from the K ATP channel. Inhibitors of NO synthase abolished protection in preconditioned cells, suggesting that NO is also required for protection. DAF-2 fluorescence (NO sensitive) increased during hypoxic triggering. This was amplified by pinacidil and inhibited by 5-HD, indicating that NO is generated subsequent to K ATP channel activation. Exogenous NO during the triggering phase conferred protection blocked by 5-HD. Exogenous NO also restored protection abolished by 5-HD or N ω-nitro-l-arginine methyl ester in preconditioned cells. Antioxidants given during pinacidil or NO triggering abolished protection, confirming that ROS are generated by K ATP channel activation. Coadministration of H 2 O 2 and NO restored PMA-induced protection in 5-HD-treated cells, indicating that ROS and NO are required downstream from the K ATP channel. We conclude that ROS can trigger preconditioning by causing activation of the K ATP channel, which then induces generation of ROS and NO that are both required for preconditioning protection.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“Once in a high redox state, QH• can lose its unpaired electron to O2 as all upstream redox centers are fully reduced (200).”
From Mitochondrial reactive oxygen species production in excitable cells: Modulators of mitochondrial and cell function (2009) · cites this paper as [200]
Citations
Cites
Reactive oxygen species in cell signaling
Thannickal, V. J., & Fanburg, B. L. (2000) · American Journal of Physiology-Lung Cellular and Molecular Physiology · doi:10.1152/ajplung.2000.279.6.l1005 · Cited by 2,950
Detection and Imaging of Nitric Oxide with Novel Fluorescent Indicators: Diaminofluoresceins
Kojima, H., Nakatsubo, N., Kikuchi, K., Kawahara, S., Kirino, Y., Nagoshi, H., Hirata, Y., & Nagano, T. (1998) · Analytical Chemistry · doi:10.1021/ac9801723 · Cited by 1,391
Nitric oxide synthases: which, where, how, and why?
Michel, T. M., & Féron, O. (1997) · Journal of Clinical Investigation · doi:10.1172/jci119750 · Cited by 1,024
Mitochondrial ATP-Dependent Potassium Channels
Liu, Y., Sato, T., O'Rourke, B. P., & Marbán, E. (1998) · Circulation · doi:10.1161/01.cir.97.24.2463 · Cited by 816
Vanden Hoek, T. L., Becker, L. B., Shao, Z., Li, C., & Schumacker, P. T. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.29.18092 · Cited by 721
Self-citationPain, T., Yang, X.-M., Critz, S. D., Yue, Y., Nakano, A., Liu, G. S., Heusch, G., Cohen, M. V., & Downey, J. M. (2000) · Circulation Research · doi:10.1161/01.res.87.6.460 · Cited by 662
Production of Nitric Oxide by Mitochondria
Giulivi, C., Poderoso, J. J., & Boveris, A. (1998) · Journal of Biological Chemistry · doi:10.1074/jbc.273.18.11038 · Cited by 572
Baines, C. P., Goto, M., & Downey, J. M. (1997) · Journal of Molecular and Cellular Cardiology · doi:10.1006/jmcc.1996.0265 · Cited by 484 · cited 2×
“We (42) and others (1, 2, 41) have found that oxidant signals contribute to hypoxia-induced preconditioning.”
BackgroundSarcolemmal Versus Mitochondrial ATP-Sensitive K+Channels and Myocardial Preconditioning
Gross, G. J., & Fryer, R. M. (1999) · Circulation Research · doi:10.1161/01.res.84.9.973 · Cited by 478
Ebselen, a selenoorganic compound as glutathione peroxidase mimic
Sies, H. (1993) · Free Radical Biology and Medicine · doi:10.1016/0891-5849(93)90028-s · Cited by 432
Flagged first, then by citations
Cited by
Sorted by citations
Items 101–200 of 227
Fluid Mechanical Forces and Endothelial Mitochondria: A Bioengineering Perspective
Scheitlin, C. G., Nair, D. M., Crestanello, J. A., Zweier, J. L., & Alevriadou, B. R. (2014) · Cellular and Molecular Bioengineering · doi:10.1007/s12195-014-0357-4 · Cited by 34
Preconditioning in Intact and Previously Diseased Myocardium: Laboratory or Clinical Dilemma?
Juhász, B., Dér, P., Turóczi, T., Bácskay, I., Varga, E., & Tósaki, Á. (2004) · Antioxidants and Redox Signaling · doi:10.1089/152308604322899396 · Cited by 33
Strijdom, H., Jacobs, S., Hattingh, S. M., Page, C., & Lochner, A. (2005) · The FASEB Journal · doi:10.1096/fj.05-4225fje · Cited by 33
Neuroprotective effects of 2,4-dinitrophenol in an acute model of Parkinson’s disease
Lee, Y., Heo, G., Lee, K. M., Kim, A. H., Chung, K. W., Im, E., Chung, H. Y., & Lee, J. (2017) · Brain Research · doi:10.1016/j.brainres.2017.03.018 · Cited by 32
Cardioprotective effects of KATP channel activation during hypoxia in goldfish Carassius auratus
Chen, J., Zhu, J. X., Wilson, I., & Cameron, J. S. (2005) · Journal of Experimental Biology · doi:10.1242/jeb.01704 · Cited by 32
Sánchez‐Ramos, C., Priéto, I., Tiérrez, A., Laso, J., Valdecantos, M. P., Bartrons, R., Roselló‐Catafau, J., & Monsalve, M. (2017) · Antioxidants and Redox Signaling · doi:10.1089/ars.2016.6836 · Cited by 31
Akki, R., Siracusa, R., Morabito, R., Remigante, A., Campolo, M., Errami, M., Spada, G. L., Cuzzocrea, S., & Marino, A. (2018) · Cell Biochemistry and Function · doi:10.1002/cbf.3317 · Cited by 31
Pasdois, P., Beauvoit, B. P., Costa, A. D. T., Jaspard‐Vinassa, B., Tariosse, L., Bonoron‐Adèle, S., Garlid, K., & Santos, P. D. D. (2006) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2006.12.014 · Cited by 30
Mitochondrial function: the heart of myocardial preservation
McFalls, E. O., Liem, D. A., Schoonderwoerd, K. C., Lamers, J. M. J., Sluiter, W. J., & Duncker, D. J. (2003) · Journal of Laboratory and Clinical Medicine · doi:10.1016/s0022-2143(03)00109-4 · Cited by 30
Kolamunne, R. T., Clare, M., & Griffiths, H. R. (2010) · Archives of Biochemistry and Biophysics · doi:10.1016/j.abb.2010.10.015 · Cited by 27
Yogaratnam, J. Z., Laden, G., Guvendik, L., Cowen, M., Cale, A. R. J., & Griffin, S. C. (2007) · Journal of Surgical Research · doi:10.1016/j.jss.2007.09.003 · Cited by 27
Liem, D. A., Manintveld, O. C., Schoonderwoerd, K. C., McFalls, E. O., Heinen, A., Verdouw, P. D., Sluiter, W. J., & Duncker, D. J. (2007) · Translational research · doi:10.1016/j.trsl.2007.09.007 · Cited by 27
EDARAVONE REDUCES MYOCARDIAL INFARCT SIZE AND IMPROVES CARDIAC FUNCTION AND REMODELLING IN RABBITS
Onogi, H., Minatoguchi, S., Chen, X., Bao, N., Kobayashi, H., Misao, Y., Yasuda, S., Yamaki, T., Maruyama, R., Uno, Y., et al. (2006) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2006.04483.x · Cited by 27
Strijdom, H., Genade, S., & Lochner, A. (2004) · Cardiovascular Drugs and Therapy · doi:10.1023/b:card.0000029027.50796.84 · Cited by 27
Afify, E. A., Khedr, M. M., Omar, A. G., & Nasser, S. A. (2012) · Fundamental and Clinical Pharmacology · doi:10.1111/fcp.12004 · Cited by 26
Sarre, A., Lange, N., Kučera, P., & Raddatz, E. (2004) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00942.2004 · Cited by 25
Wang, N., Minatoguchi, S., Chen, X., Arai, M., Uno, Y., Lu, C., Misao, Y., Nagai, H., Takemura, G., & Fujiwara, H. (2004) · Journal of Cardiovascular Pharmacology · doi:10.1097/00005344-200406000-00003 · Cited by 25
Matějíková, J., Ravíngerová, T., Pancza, D., Čarnická, S., & Kolář, F. (2009) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y09-100 · Cited by 25
Iwasa, M., Kobayashi, H., Yasuda, S., Kawamura, I., Sumi, S., Yamada, Y., Shiraki, T., Yamaki, T., Ushikoshi, H., Aoyama, T., et al. (2010) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0b013e3181dcd240 · Cited by 23
Is oxytocin a therapeutic factor for ischemic heart disease?
Alizadeh, A. M., & Mirzabeglo, P. (2013) · Peptides · doi:10.1016/j.peptides.2013.04.016 · Cited by 22
Ischemic Preconditioning: Triggering Role of Nitric Oxide-Derived Oxidants in Isolated Hearts
Novalija, E., Hogg, N., Kevin, L. G., Camara, A. K. S., & Stowe, D. F. (2003) · Journal of Cardiovascular Pharmacology · doi:10.1097/00005344-200311000-00003 · Cited by 24
H2O2 induces delayed hyperexcitability in nucleus tractus solitarii neurons
Ostrowski, T. D., Hasser, E. M., Heesch, C. M., & Kline, D. D. (2014) · Neuroscience · doi:10.1016/j.neuroscience.2013.12.055 · Cited by 22
Adams, J. A., Wu, H., Bassuk, J. A., Arias, J., Uryash, A., Jorapur, V., Lamas, G. A., & Kurlansky, P. A. (2010) · Life Sciences · doi:10.1016/j.lfs.2010.02.022 · Cited by 22
Anderson, T., Li, C., Shao, Z., Hoang, T., Chan, K. C., Hamann, K. J., Becker, L. B., & Hoek, T. L. V. (2006) · Critical Care Medicine · doi:10.1097/01.ccm.0000246014.19486.a1 · Cited by 21
Self-citationAltering CO2 during reperfusion of ischemic cardiomyocytes modifies mitochondrial oxidant injury*
Lavani, R., Chang, W., Anderson, T., Shao, Z., Wojcik, K. R., Li, C., Pietrowski, R. F., Beiser, D. G., Idris, A. H., Hamann, K. J., et al. (2007) · Critical Care Medicine · doi:10.1097/01.ccm.0000269209.53450.ec · Cited by 21
Self-citationVogt, S. K., Rhiel, A., Weber, P., & Ramzan, R. (2016) · BioEssays · doi:10.1002/bies.201600043 · Cited by 19
Nitric oxide increases myocardial efficiency in the hypoxia-tolerant turtle Trachemys scripta
Misfeldt, M. W., Fago, A., & Gesser, H. (2009) · Journal of Experimental Biology · doi:10.1242/jeb.025171 · Cited by 19
Effect of Poly Phenols in Enhancing the Swimming Capacity of Rats
Swamy, M. S., Shivanna, N., Tamatam, A., & Khanum, F. (2011) · Functional Foods in Health and Disease · doi:10.31989/ffhd.v1i11.115 · Cited by 18
Osaki, T., Uchida, Y., Hirayama, J., & Nishina, H. (2011) · Biological and Pharmaceutical Bulletin · doi:10.1248/bpb.34.1343 · Cited by 18
Mironov, S. L., & Langohr, K. (2006) · Brain Research · doi:10.1016/j.brainres.2006.09.114 · Cited by 18
Initiation of remote microvascular preconditioning requires KATP channel activity
Mabanta, L., Valane, P. D., Borne, J., & Frame, M. D. S. (2005) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00455.2005 · Cited by 18
Guterbaum, T. J., Braunstein, T. H., Fossum, A., Holstein‐Rathlou, N., Torp-Pedersen, C. T., & Domínguez, H. (2013) · Journal of Vascular Research · doi:10.1159/000354225 · Cited by 17
Jin, C. S., Zhang, P., Wu, X., Zhou, B., Li, Y., Liu, X., Feng, M., & Tao, L. (2009) · PubMed · Cited by 17
Sensing the Cardiac Environment: Exploiting Cues for Regeneration
Pereira, M. J. N., Fidalgo-Carvalho, I., Karp, J. M., & Ferreira, L. (2011) · Journal of Cardiovascular Translational Research · doi:10.1007/s12265-011-9299-6 · Cited by 17
Mitochondrial K+ transport and cardiac protection during ischemia/reperfusion
Carreira, R., Facundo, H. T., & Kowaltowski, A. J. (2005) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2005000300004 · Cited by 16
Bao, N., Ushikoshi, H., Kobayashi, H., Yasuda, S., Kawamura, I., Iwasa, M., Yamaki, T., Sumi, S., Nagashima, K., Aoyama, T., et al. (2008) · Journal of Cardiology · doi:10.1016/j.jjcc.2008.09.012 · Cited by 16
Dual role of nNOS in ischemic injury and preconditioning
Barua, A., Standen, N. B., & Galiñanes, M. (2010) · BMC Physiology · doi:10.1186/1472-6793-10-15 · Cited by 16
Colantuono, G., Tiravanti, E., Venosa, N. D., Cazzato, A., Rastaldo, R., Cagiano, R., D’Agostino, D., Federici, A., & Fiore, T. (2007) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2007.04745.x · Cited by 16
A pathway involving protein kinase Cδ up-regulates cytosolic phospholipase A2α in airway epithelium
You, H. J., Lee, J., Yoo, Y. J., & Kim, J. (2004) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2004.07.022 · Cited by 16
Differential Increase of Mitochondrial Matrix Volume by Sevoflurane in Isolated Cardiac Mitochondria
Riess, M. L., Costa, A. D., Carlson, R., Garlid, K. D., Heinen, A., & Stowe, D. F. (2008) · Anesthesia & Analgesia · doi:10.1213/ane.0b013e318167875e · Cited by 15
Tullio, F., Penna, C. R. R., Cabiale, K., Femminò, S., Galloni, M. R., & Pagliaro, P. (2017) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2017.03.043 · Cited by 14
Shvedova, M., Anfinogenova, Y., Popov, S. V., & Atochin, D. N. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.00479 · Cited by 15
Dantzler, H. A., Matott, M. P., Martinez, D., & Kline, D. D. (2019) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00054.2019 · Cited by 13
Chalkias, A. F., & Xanthos, T. T. (2012) · Redox Report · doi:10.1179/1351000212y.0000000002 · Cited by 13
Zhang, J., Chen, Z., & Wu, Z. (2008) · Canadian Journal of Physiology and Pharmacology · doi:10.1139/y08-016 · Cited by 12
Brunelli, L., Ristagno, G., Bagnati, R., Fumagalli, F., Latini, R., Fanelli, R., & Pastorelli, R. (2013) · Metabolomics · doi:10.1007/s11306-013-0506-0 · Cited by 12
Alva, N., Azuara, D., Palomeque, J., & Carbonell, T. (2013) · Experimental Physiology · doi:10.1113/expphysiol.2012.071365 · Cited by 12
Pagel, P. S., Farber, N. E., Pratt, P. F., & Warltier, D. C. (2010) · Elsevier eBooks · doi:10.1016/b978-0-443-06959-8.00023-6 · Cited by 12
Moon, D. (2024) · International Journal of Molecular Sciences · doi:10.3390/ijms25042129 · Cited by 11
El‐Ani, D., Zimlichman, R., Mashiach, Y., & Shainberg, A. (2007) · Life Sciences · doi:10.1016/j.lfs.2007.06.030 · Cited by 11
Chang, W., Li, C., Hsu, C.-C. A., Lee, C., Huang, H., Yuan, C., Chen, W., Hoek, T. L. V., Shao, Z., & Li, J. (2019) · The American Journal of Chinese Medicine · doi:10.1142/s0192415x19500538 · Cited by 11
Self-citationBabiker, F. A., Al‐Jarallah, A., & Joseph, S. (2016) · Journal of Physiology and Biochemistry · doi:10.1007/s13105-016-0535-z · Cited by 11
Iguchi, K., Saotome, M., Yamashita, K., Hasan, P., Sasaki, M., Maekawa, Y., & Watanabe, Y. (2019) · Naunyn-Schmiedeberg s Archives of Pharmacology · doi:10.1007/s00210-019-01642-1 · Cited by 11
Endothelium, ischemia and the good side of oxygen free radicals
Grotti, S., & Gori, T. (2008) · Clinical Hemorheology and Microcirculation · doi:10.3233/ch-2008-1082 · Cited by 10
Reactive Oxygen Species and Cardiac Preconditioning: Many Questions Remain
Stowe, D. F., & Riess, M. L. (2004) · Cardiovascular Drugs and Therapy · doi:10.1023/b:card.0000029082.45753.49 · Cited by 9
Baba, S., Iwasa, M., Higashi, K., Minatoguchi, S., Yamada, Y., Kanamori, H., Kawasaki, M., Nishigaki, K., & Minatoguchi, S. (2017) · Journal of Cardiovascular Pharmacology · doi:10.1097/fjc.0000000000000531 · Cited by 9
Lewis, P., McMorrow, C., Bradford, A., & O’Halloran, K. D. (2015) · The Journal of Physiological Sciences · doi:10.1007/s12576-015-0381-8 · Cited by 9
Chuang, C., Zhou, T., Olfert, I. M., & Zuo, L. (2018) · Frontiers in Physiology · doi:10.3389/fphys.2018.01720 · Cited by 9
Kiss, A., Juhász, L., Huliák, I., & Végh, Á. (2008) · British Journal of Pharmacology · doi:10.1038/bjp.2008.344 · Cited by 9
How Does the Heart Sense Changes in Oxygen Tension: A Role for Ion Channels?
Hool, L. C. (2014) · Antioxidants and Redox Signaling · doi:10.1089/ars.2014.5880 · Cited by 8
Čı́žová, H., Papežíková, I., Kubala, L., Lojek, A., & Čı́ž, M. (2006) · Digestive Diseases and Sciences · doi:10.1007/s10620-006-3188-x · Cited by 8
Physiopathology of the embryonic heart (with special emphasis on hypoxia and reoxygenation)
Raddatz, E., Gardier, S., & Sarre, A. (2006) · Annales de Cardiologie et d Angéiologie · doi:10.1016/j.ancard.2006.02.007 · Cited by 8
Remote Microvascular Preconditioning Alters Specific Vasoactive Responses
Frame, M. D. S., & Mabanta, L. (2007) · Microcirculation · doi:10.1080/10739680701410074 · Cited by 7
Imani, A., Khansari, M., Azizi, Y., Rakhshan, K., & Faghihi, M. (2015) · PubMed · Cited by 7
Modest actomyosin energy conservation increases myocardial postischemic function
Blunt, B. C., Chen, Y., Potter, J. D., & Hofmann, P. A. (2004) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00746.2004 · Cited by 7
Li, J., Liu, S., Chen, C., Deng, J., Du, Z., Yang, S., Deng, H., Zhang, Z., Huang, Y., Fu, J., et al. (2024) · Advanced Healthcare Materials · doi:10.1002/adhm.202403700 · Cited by 6
Peroxynitrite: in vivo cardioprotectant or arrhythmogen?
Eaton, P., & Clements‐Jewery, H. (2008) · British Journal of Pharmacology · doi:10.1038/bjp.2008.372 · Cited by 6
Angius, L., Crisafulli, A., Hureau, T. J., Broxterman, R. M., Amann, M., Incognito, A. V., Burr, J. F., Millar, P. J., Jones, H., Thijssen, D. J., et al. (2017) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00030.2017 · Cited by 6
Polushin, A. Y., Yanishevskiy, S. N., Вадимович, М. Д., Krivov, V. O., Beskrovnaya, O. V., & Сергеевич, М. Н. (2017) · S S Korsakov Journal of Neurology and Psychiatry · doi:10.17116/jnevro201711712137-45 · Cited by 6
Intracellular Mechanisms of Oxygen Sensing
Vjotosh, A. N. (2020) · Biochemistry (Moscow) · doi:10.1134/s0006297920010046 · Cited by 6
Jung, Y., Lee, D., Lim, H., Yi, K. Y., Yoo, S., & Kim, E. (2004) · The Japanese Journal of Physiology · doi:10.2170/jjphysiol.54.575 · Cited by 6
Williams, W. R. (2010) · Journal of Pharmacy and Pharmacology · doi:10.1111/j.2042-7158.2010.01169.x · Cited by 5
Gupta, A. A., Kumar, S., Rajput, R., Srivastava, R., Rai, R., & Sastry, J. L. N. (2015) · Ancient Science of Life · doi:10.4103/0257-7941.165626 · Cited by 5
Marı́n-Garcı́a, J. (2005) · Future Cardiology · doi:10.1517/14796678.1.1.111 · Cited by 5
Evolutionary Aspects of Cardioprotection
Шемарова, И. В., Нестеров, В. П., Korotkov, S. M., & Sylkin, Y. A. (2018) · Journal of Evolutionary Biochemistry and Physiology · doi:10.1134/s0022093018010027 · Cited by 5
Chen, X., Minatoguchi, S., Arai, M., Wang, N., Lu, C., Bao, N., Uno, Y., Misao, Y., Takemura, G., Fujiwara, T., et al. (2007) · Circulation Journal · doi:10.1253/circj.71.574 · Cited by 5
A ?radical? idea comes of age: mitochondrial oxidant signaling in health and disease
WHITE, R. (2004) · Journal of Molecular and Cellular Cardiology · doi:10.1016/j.yjmcc.2004.10.001 · Cited by 5
Олегович, К. Н., Аркадьевна, М. И., Podoksenov, Y. K., Mikheev, S. L., Sementsov, S., Маслов, Л. Н., Kozlov, B. N., & Shipulin, V. M. (2017) · Patologiya krovoobrashcheniya i kardiokhirurgiya · doi:10.21688/1681-3472-2017-4-79-86 · Cited by 4
Yang, T.-T., Qi, J., Sun, B., Qu, H., Wei, H., Sun, H., Jiang, H., Zhang, J., & Liang, S. (2023) · Animals · doi:10.3390/ani13061041 · Cited by 4
Ischemic And Anesthetic Preconditioning Of The Heart: An Insight Into The Concepts And Mechanisms
(2004) · The Internet Journal of Anesthesiology · doi:10.5580/1618 · Cited by 4
Sarre, A., Gardier, S., Maurer, F., Bonny, C., & Raddatz, E. (2008) · Molecular and Cellular Biochemistry · doi:10.1007/s11010-008-9750-4 · Cited by 4
Heart Mitochondria: A Receiver and Integrator of Signals
Marı́n-Garcı́a, J. (2011) · Springer eBooks · doi:10.1007/978-1-4419-9461-5_8 · Cited by 3
Involvement of Ca2+ in the development of ischemic disorders of myocardial contractile function
Шемарова, И. В., Нестеров, В. П., Korotkov, S. M., & Sobol, K. V. (2017) · Journal of Evolutionary Biochemistry and Physiology · doi:10.1134/s0022093017050027 · Cited by 3
Post-Genomics Cardiovascular Signaling Pathways
Marı́n-Garcı́a, J. (2014) · Elsevier eBooks · doi:10.1016/b978-0-12-404599-6.00003-2 · Cited by 3
Reactive Oxygen Species (ROS) and Cardiac Ischemia and Reperfusion Injury
Camara, A. K. S., & Stowe, D. F. (2014) · Springer eBooks · doi:10.1007/978-3-642-30018-9_75 · Cited by 3
Aiello, E. A., & Cingolani, H. E. (2011) · Applied Physiology, Nutrition, and Metabolism · doi:10.1139/h11-089 · Cited by 3
Cardioprotection and Signaling Pathways
Marín-García, J. (2011) · Springer eBooks · doi:10.1007/978-1-4419-9461-5_20 · Cited by 3
Cardiovascular Signaling Pathways
Marı́n-Garcı́a, J. (2007) · Elsevier eBooks · doi:10.1016/b978-012373698-7/50005-x · Cited by 3
Hydrogen Peroxide Affects the Electroretinogram of Isolated Perfused Rat Retina
Jacquemot, N., Wersinger, E., Brabet, P., & Cia, D. (2023) · Current Eye Research · doi:10.1080/02713683.2023.2256029 · Cited by 2
Vadzyuk, O. B., & Sa, K. (2015) · TURKISH JOURNAL OF BIOLOGY · doi:10.3906/biy-1410-75 · Cited by 2
Garlid, A. O. (2000) · doi:10.15760/etd.1640 · Cited by 2
Kolamunne, R. T., Grant, M. M., Vernallis, A. B., & Griffiths, H. R. (2010) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2010.10.035 · Cited by 1
Hypoxic preconditioning increases mitochondrial respiration and H2O2 production
Bergmeister, L., Doerrier, C., Fogli, B., Komlódi, T., Fischer, A., Springer, K., Schwarzer, C., & Gnaiger, E. (2025) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2025.1628567 · Cited by 1
Mitochondrial Reactive Oxygen Species in Myocardial Pre- and Postconditioning
Cardoso, A. R., Queliconi, B. B., & Kowaltowski, A. J. (2010) · Humana Press eBooks · doi:10.1007/978-1-60761-600-9_5 · Cited by 1
Reis, F. (2011) · Clinical and Experimental Pharmacology and Physiology · doi:10.1111/j.1440-1681.2011.05564.x · Cited by 1
Behjati, M., Hashemi, M. M., Mohammad, K., & Mansoor, S. (2011) · AFRICAN JOURNAL OF BIOTECHNOLOGY · doi:10.5897/ajb10.2329 · Cited by 1
Hanley, P. J., & Daut, J. (2005) · Cited by 1
Orban, J., & Singer, M. (2017) · Springer eBooks · doi:10.1007/978-3-319-64010-5_20 · Cited by 1
Effects of diazoxide on the mitochondrial membrane potential and ROS generation in rat uterus cells
Vadziuk, O. B. (2012) · Fìzìologìčnij žurnal · doi:10.15407/fz58.01.086 · Cited by 1
Corry, B., & Hool, L. C. (2007) · Springer eBooks · doi:10.1007/0-387-68919-2_7 · Cited by 1
Metadata
- Authors
- Lebuffe, G., Schumacker, P. T., Shao, Z.-H., Anderson, T., Iwase, H., & Vanden Hoek, T. L.
- Affiliations
- University of Chicago (US)
- Department of Medicine, Emergency Resuscitation Center, University of Chicago, Chicago, Illinois 60637
- Venue
- American Journal of Physiology-Heart and Circulatory Physiology
- Publisher
- American Physiological Society
- Published
- 2003-01-01
- Volume
- 284
- Issue
- 1
- Pages
- H299-H308
- ISSN
- 0363-6135 (ISSN-L)
- 1522-1539
- OpenAlex
- W2130229822
- Cited by
- 227
- References
- 54
- Citations by year
- 2026: 1 · 2025: 1 · 2024: 2 · 2023: 2 · 2022: 1 · 2021: 1 · 2020: 2 · 2019: 4 · 2018: 5 · 2017: 9 · 2016: 4 · 2015: 6 · 2014: 8 · 2013: 7 · 2012: 10
- FWCI
- 15.08
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Physiology-Heart and Circulatory Physiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Cardiac Ischemia and Reperfusion
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Cell death mechanisms and regulation
- Health Sciences › Medicine › Physiology (medical) › Nitric Oxide and Endothelin Effects
- Keywords
- ischemic preconditioning, reactive oxygen species, nitric oxide, mitochondrial ATP-dependent potassium channel, ATP-sensitive potassium channels, cardiomyocytes, hypoxia, hydrogen peroxide, protein kinase C, 5-hydroxydecanoate, nitric oxide synthase, antioxidants, myocardial ischemia-reperfusion injury, cardioprotection
- MeSH terms
- Adenosine Triphosphate, Animals, Cells, Cultured, Chick Embryo, Hydrogen Peroxide, Mitochondria, Heart, Nitric Oxide, Protein Kinase C, Potassium Channels, Oxidants, Reactive Oxygen Species, Ischemic Preconditioning, Myocardial, Myocytes, Cardiac
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review