The DOI matches its Crossref record.
Familial hypothalamic diabetes insipidus in rats (Brattleboro strain)
Abstract
Familial hypothalamic diabetes insipidus ( DI) has arisen as an apparently spontaneous mutation from a strain of Long-Evans hooded rats being bred for unrelated researches not involving radioactivity. The DI rats decrease water intake and urine flow, and increase urine osmolality in response to injected vasopressin. They concentrate their urines only minimally or not at all in response to dehydration, hypertonic saline, nicotine, or stress, and their serum osmolalities and sodium concentrations are significantly higher than those of normal animals. They show marked diminution of neurosecretory material in the neurohypophysis and supraoptic nucleus. The data suggest that the deficiency causing DI in these rats is a lack or dearth of synthesis of vasopressin or its carrier protein, or both.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
Gene Regulation in the Magnocellular Hypothalamo-Neurohypophysial System
Burbach, J. P. H., Luckman, S. M., Murphy, D., & Gainer, H. (2001) · Physiological Reviews · doi:10.1152/physrev.2001.81.3.1197 · Cited by 340
BOHUS, B., URBAN, I., VANWIMERSMAGREIDANUS, T., & DEWIED, D. (1978) · Neuropharmacology · doi:10.1016/0028-3908(78)90107-7 · Cited by 231
Bardoux, P., Martin, H., Ahloulay, M., Schmitt, F., Bouby, N., Trinh-Trang-Tan, M.-M., & Bankir, L. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.18.10397 · Cited by 138
Brain vasopressin signaling modulates aspects of maternal behavior in lactating rats
Bayerl, D. S., & Bosch, O. J. (2019) · Genes, Brain and Behavior · doi:10.1111/gbb.12517 · Cited by 46
Metadata
- Authors
- Valtin, H., & Schroeder, H. A.
- Venue
- American Journal of Physiology-Legacy Content
- Publisher
- American Physiological Society
- Published
- 1964-02-01
- Volume
- 206
- Issue
- 2
- Pages
- 425-430
- ISSN
- 0002-9513 (ISSN-L)
- OpenAlex
- W2123319302
- Cited by
- 301
- References
- 0
- FWCI
- 8.83
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Familial hypothalamic diabetes insipidus in rats (Brattleboro strain). https://app.cochat.ai/papers/10.1152/ajplegacy.1964.206.2.425
- The paper
- Valtin, H., & Schroeder, H. A. (1964). Familial hypothalamic diabetes insipidus in rats (Brattleboro strain). American Journal of Physiology-Legacy Content. https://doi.org/10.1152/ajplegacy.1964.206.2.425
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
