The DOI matches its Crossref record; 21 of the 21 references it cites were found in a registry or an index.
Cardiorespiratory interactions during resistive load breathing
Abstract
The addition to the respiratory system of a resistive load results in breathing pattern changes and in negative intrathoracic pressure increases. The aim of this study was to use resistive load breathing as a stimulus to the cardiorespiratory interaction and to examine the extent of the changes in heart rate variability (HRV) and respiratory sinus arrhythmia (RSA) in relation to the breathing pattern changes. HRV and RSA were studied in seven healthy subjects where four resistive loads were applied in a random order during the breath and 8-min recording made in each condition. The HRV spectral power components were computed from the R-R interval sequences, and the RSA amplitude and phase were computed from the sinusoid fitting the instantaneous heart rate within each breath. Adding resistive loads resulted in 1) increasing respiratory period, 2) unchanging heart rate, and 3) increasing HRV and changing RSA characteristics. HRV and RSA characteristics are linearly correlated to the respiratory period. These modifications appear to be linked to load-induced changes in the respiratory period in each individual, because HRV and RSA characteristics are similar at a respiratory period obtained either by loading or by imposed frequency breathing. The present results are discussed with regard to the importance of the breathing cycle duration in these cardiorespiratory interactions, suggesting that these interactions may depend on the time necessary for activation and dissipation of n…
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“Modulating breath also increases vagal tone, dampens sympathetic nervous system activity (Calabrese et al., 2000; Brown and Gerbarg, 2005; Schmalzl et al., 2015), promotes parasympathetic dominance (Sovik, 2000; Brown and Gerbarg, 2005), and facilitates stress regulation and cognitive control (Sharma, 2014).”
From Mindfulness, Interoception, and the Body: A Contemporary Perspective (2019) · cites this paper as Calabrese et al., 2000
In the citing paper
“Increased vagal tone mediates vagal afferent information sent to the insula and interoceptive network, which are involved in self-regulatory processes and may promote synchronization of cortical areas (Calabrese et al., 2000; Schmalzl et al., 2015).”
From Mindfulness, Interoception, and the Body: A Contemporary Perspective (2019) · cites this paper as Calabrese et al., 2000
In the citing paper
“Modulating breath also increases vagal tone, dampens sympathetic nervous system activity (Calabrese et al., 2000; Brown and Gerbarg, 2005; Schmalzl et al., 2015), promotes parasympathetic dominance (Sovik, 2000; Brown and Gerbarg, 2005), and facilitates stress regulation and cognitive control (Sharma, 2014).”
From Mindfulness, Interoception, and the Body: A Contemporary Perspective (2019) · cites this paper as Calabrese et al., 2000
Citations
Cites
Respiratory sinus arrhythmia in humans: how breathing pattern modulates heart rate
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Important influence of respiration on human R-R interval power spectra is largely ignored
Brown, T. E., Beightol, L. A., Koh, J., & Eckberg, D. L. (1993) · Journal of Applied Physiology · doi:10.1152/jappl.1993.75.5.2310 · Cited by 770
Respiratory variations of the heart rate - I—The reflex mechanism of the respiratory arrhythmia
Anrep, G., Pascual, W., & Rössler, R. (1936) · Proceedings of the Royal Society of London. Series B - Biological Sciences · doi:10.1098/rspb.1936.0005 · Cited by 274
GROSSMAN, P., & KOLLAI, M. (1993) · Psychophysiology · doi:10.1111/j.1469-8986.1993.tb02072.x · Cited by 250
Respiratory modulation of muscle sympathetic nerve activity in intact and lung denervated humans.
Seals, D. R., Suwarno, N. O., Joyner, M. J., Iber, C., Copeland, J. G., & Dempsey, J. A. (1993) · Circulation Research · doi:10.1161/01.res.72.2.440 · Cited by 178
Baroreflex modulation of sympathetic activity and sympathetic neurotransmitters in humans
Eckberg, D. L., Rea, R. F., Andersson, O., Hedner, T., Pernow, J., Lundberg, J. M., & Wallin, B. G. (1988) · Acta Physiologica Scandinavica · doi:10.1111/j.1748-1716.1988.tb08401.x · Cited by 172
Anrep, G. V., Pascual, W., & Rößler, R. (1936) · Proceedings of the Royal Society B Biological Sciences · doi:10.1098/rspb.1936.0006 · Cited by 139
Respiratory and baroreceptor reflex interactions in man.
Eckberg, D. L., & Orshan, C. R. (1977) · Journal of Clinical Investigation · doi:10.1172/jci108699 · Cited by 132
Transient analysis of cardiopulmonary interactions. I. Diastolic events
Peters, J., Kindred, M. K., & Robotham, J. L. (1988) · Journal of Applied Physiology · doi:10.1152/jappl.1988.64.4.1506 · Cited by 106
Effects of Graded Resistance to Tracheal Air Flow in Man
Zechman, F. W., Hall, F. G., & Hull, W. E. (1957) · Journal of Applied Physiology · doi:10.1152/jappl.1957.10.3.356 · Cited by 87
Cited by
Streeter, C. C., Gerbarg, P. L., Saper, R. B., Ciraulo, D. A., & Brown, R. P. (2012) · Medical Hypotheses · doi:10.1016/j.mehy.2012.01.021 · Cited by 694
Brown, R. P., & Gerbarg, P. L. (2005) · The Journal of Alternative and Complementary Medicine · doi:10.1089/acm.2005.11.189 · Cited by 655
Mindfulness, Interoception, and the Body: A Contemporary Perspective
Gibson, J. (2019) · Frontiers in Psychology · doi:10.3389/fpsyg.2019.02012 · Cited by 278
Schmalzl, L., Powers, C., & Henje Blom, E. (2015) · Frontiers in Human Neuroscience · doi:10.3389/fnhum.2015.00235 · Cited by 170
Metadata
- Authors
- Calabrese, P., Perrault, H., Dinh, T. P., Eberhard, A., & Benchetrit, G.
- Affiliations
- Laboratoire de Physiologie Respiratoire Expérimentale, Théorique et Appliquée, Université Joseph Fourier, 38700 La Tronche, France;
- Department of Physical Education, McGill University, Montreal, Canada, H2W 1S4; and
- Laboratoire de Modélisation et Calcul, Université Joseph Fourier, BP 53X, 38041 Cedex, Grenoble, France
- Université Joseph Fourier (FR)
- Venue
- American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
- Publisher
- American Physiological Society
- Published
- 2000-12-01
- Volume
- 279
- Issue
- 6
- Pages
- R2208-R2213
- ISSN
- 0363-6119 (ISSN-L)
- 1522-1490
- OpenAlex
- W2188483697
- Cited by
- 49
- References
- 21
- Citations by year
- 2026: 3 · 2025: 2 · 2024: 1 · 2023: 1 · 2021: 5 · 2020: 5 · 2019: 3 · 2018: 2 · 2017: 1 · 2016: 1 · 2015: 2 · 2014: 2 · 2013: 3 · 2012: 2
- FWCI
- 0.49
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- American Journal of Physiology-Regulatory, Integrative and Comparative Physiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Cardiology and Cardiovascular Medicine › Heart Rate Variability and Autonomic Control
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Neuroscience of respiration and sleep
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Keywords
- cardiorespiratory interaction, heart rate variability, respiratory sinus arrhythmia, breathing pattern, negative intrathoracic pressure
- MeSH terms
- Adult, Airway Resistance, Heart, Heart Rate, Homeostasis, Humans, Middle Aged, Regression Analysis, Respiratory Mechanics
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- CoChat. (2026). Citation check: Cardiorespiratory interactions during resistive load breathing. https://app.cochat.ai/papers/10.1152/ajpregu.2000.279.6.r2208
- The paper
- Calabrese, P., Perrault, H., Dinh, T. P., Eberhard, A., & Benchetrit, G. (2000). Cardiorespiratory interactions during resistive load breathing. American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. https://doi.org/10.1152/ajpregu.2000.279.6.r2208
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
