The DOI matches its Crossref record; 36 of the 36 references it cites were found in a registry or an index.
Augmented uterine artery blood flow and oxygen delivery protect Andeans from altitude-associated reductions in fetal growth
Open accessAbstract
The effect of high altitude on reducing birth weight is markedly less in populations of high- (e.g., Andeans) relative to low-altitude origin (e.g., Europeans). Uterine artery (UA) blood flow is greater during pregnancy in Andeans than Europeans at high altitude; however, it is not clear whether such blood flow differences play a causal role in ancestry-associated variations in fetal growth. We tested the hypothesis that greater UA blood flow contributes to the protection of fetal growth afforded by Andean ancestry by comparing UA blood flow and fetal growth throughout pregnancy in 137 Andean or European residents of low (400 m; European n = 28, Andean n = 23) or high (3,100–4,100 m; European n = 51, Andean n = 35) altitude in Bolivia. Blood flow and fetal biometry were assessed by Doppler ultrasound, and maternal ancestry was confirmed, using a panel of 100 ancestry-informative genetic markers (AIMs). At low altitude, there were no ancestry-related differences in the pregnancy-associated rise in UA blood flow, fetal biometry, or birth weight. At high altitude, Andean infants weighed 253 g more than European infants after controlling for gestational age and other known influences. UA blood flow and O 2 delivery were twofold greater at 20 wk in Andean than European women at high altitude, and were paralleled by greater fetal size. Moreover, variation in the proportion of Indigenous American ancestry among individual women was positively associated with UA diameter, blood flow, O 2 delivery, and fetal head circumference. We concluded that greater UA blood flow protects against hypoxia-associated reductions in fetal growth, consistent with the hypothesis that genetic factors enabled Andeans to achieve a greater pregnancy-associated rise in UA blood flow and O 2 delivery than European women at high altitude.
Overview
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
In the citing paper
“However, in the majority of studies, the normal pregnancy-induced rise in uterine blood flow is blunted at high altitude in association with a reduced diameter of the uterine arteries and/or lower nitric oxide synthesis, regardless of ancestry (294, 295, 577, 603, 604).”
From Placental Origins of Chronic Disease (2016) · cites this paper as [295]
In the citing paper
“Pregnant Tibetan women have higher uterine artery diameters and blood velocity than Han women at high altitude (107, 389), while Andean women have twice the increment in uterine artery diameter during pregnancy than European women at high altitude (295, 577, 604).”
From Placental Origins of Chronic Disease (2016) · cites this paper as [295]
In the citing paper
“In some studies, the protective effect of Andean ancestry on uterine artery haemodynamics is only seen at high altitude while in others, the ethnic differences are also evident at sea level (295, 604).”
From Placental Origins of Chronic Disease (2016) · cites this paper as [295]
In the citing paper
“Indeed, in Andean women, the increase in uterine blood flow during pregnancy at high altitude can exceed that seen at low altitude (69, 295).”
From Placental Origins of Chronic Disease (2016) · cites this paper as [295]
In the citing paper
“This results in differences in uterine blood flow between Andean and European women, which are detectable at 20 weeks of gestation before fetal growth slows (295).”
From Placental Origins of Chronic Disease (2016) · cites this paper as [295]
In the citing paper
“In human infants near term, the diameters of the umbilical vein and artery are both smaller at high than low altitude, which results in a lower absolute blood flow in the umbilical circulation, irrespective of ethnicity (295, 443).”
From Placental Origins of Chronic Disease (2016) · cites this paper as [295]
In the citing paper
“In human populations, the adverse consequences of high altitude on uterine artery diameter and uterine blood flow are less pronounced with long than short ancestry at high altitude (295, 387).”
From Placental Origins of Chronic Disease (2016) · cites this paper as [295]
In the citing paper
“Thus, in some studies of Andeans, absolute oxygen delivery to the gravid uterus at high altitude is maintained or even increased above lowland values, despite the low maternal pO2, while in others the uterine oxygen supply is less at high than low altitude irrespective of ancestry (69, 295, 443, 604).”
From Placental Origins of Chronic Disease (2016) · cites this paper as [295]
Citations
Cites
The Physiology of Reproduction
Legendre, M., & Jalabert, B. (1988) · Annals of Internal Medicine · doi:10.7326/0003-4819-109-2-176_1 · Cited by 7,876
The Developmental Origins of Adult Disease
Barker, D. J. P. (2004) · Journal of the American College of Nutrition · doi:10.1080/07315724.2004.10719428 · Cited by 1,854
Villar, J., Valladares, E. C., WOJDYLA, D. M., Zavaleta, N., Carroli, G., Velazco, A., Shah, A., Campodónico, L., Bataglia, V., Faúndes, A., et al. (2006) · The Lancet · doi:10.1016/s0140-6736(06)68704-7 · Cited by 883
Fetal growth and perinatal viability in California.
Williams, R. L., Creasy, R. K., Cunningham, G. C., Hawes, W. E., Norris, F. D., & Tashiro, M. (1982) · PubMed · Cited by 807
Skin pigmentation, biogeographical ancestry and admixture mapping
Shriver, M. D., Parra, E. J., Dios, S., Bonilla, C., Norton, H., Jovel, C., Pfaff, C., Jones, C., Massac, A., Cameron, N., et al. (2003) · Human Genetics · doi:10.1007/s00439-002-0896-y · Cited by 549
Self-citationEDITORIAL: The developmental origins of adult disease
Barker, D. J. P. (2003) · European Journal of Epidemiology · doi:10.1023/a:1025388901248 · Cited by 407
Jensen, G. M., & MOORE, L. G. (1997) · American Journal of Public Health · doi:10.2105/ajph.87.6.1003 · Cited by 355
Self-citationPalmer, S. K., Zamudio, S., Coffin, C. T., Parker, S. B., Stamm, E. R., & MOORE, L. G. (1992) · PubMed · Cited by 267
Self-citationThe genomic distribution of population substructure in four populations using 8,525 autosomal SNPs
Shriver, M., Kennedy, G., Parra, E., Lawson, H. A., Sonpar, V. A., Huang, J., Akey, J., & Jones, K. (2004) · Human Genomics · doi:10.1186/1479-7364-1-4-274 · Cited by 253
Self-citationEffects of Altitude versus Economic Status on Birth Weight and Body Shape at Birth
Giussani, D. A., Phillips, P. S., Anstee, S., & Barker, D. J. P. (2001) · Pediatric Research · doi:10.1203/00006450-200104000-00009 · Cited by 230
Cited by
Sorted by citations
Placental Origins of Chronic Disease
Burton, G. J., Fowden, A. L., & Thornburg, K. L. (2016) · Physiological Reviews · doi:10.1152/physrev.00029.2015 · Cited by 717
Bigham, A., Bauchet, M., Pinto, D., Mao, X., Akey, J. M., Mei, R., Scherer, S. W., Julian, C. G., Wilson, M. J., López Herráez, D., et al. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1001116 · Cited by 597
Self-citationMicrotia: Epidemiology and genetics
Luquetti, D. V., Heike, C. L., Hing, A. V., Cunningham, M. L., & Cox, T. C. (2011) · American Journal of Medical Genetics Part A · doi:10.1002/ajmg.a.34352 · Cited by 458
Genetic adaptation to high altitude in the Ethiopian highlands
Scheinfeldt, L., Soi, S., Thompson, S. R., Ranciaro, A., Meskel, D. W., Beggs, W. R., Lambert, C. A., Jarvis, J. P., Abate, D., Belay, G., et al. (2012) · Genome biology · doi:10.1186/gb-2012-13-1-r1 · Cited by 459
Phenotypic plasticity and genetic adaptation to high-altitude hypoxia in vertebrates
Storz, J. F., Scott, G. R., & Cheviron, Z. A. (2010) · Journal of Experimental Biology · doi:10.1242/jeb.048181 · Cited by 427
Hutter, D., Kingdom, J. C., & JAEGGI, E. T. (2010) · International Journal of Pediatrics · doi:10.1155/2010/401323 · Cited by 319
Galanter, J., Fernández-López, J. C., Gignoux, C. R., Barnholtz‐Sloan, J. S., Fernández–Rozadilla, C., Vía, M., Hidalgo‐Miranda, A., Contreras, A. V., Uribe-Figueroa, L., Raska, P., et al. (2012) · PLoS Genetics · doi:10.1371/journal.pgen.1002554 · Cited by 305
Self-citationHumans at high altitude: Hypoxia and fetal growth
Moore, L. G., Charles, S. M., & Julian, C. G. (2011) · Respiratory Physiology & Neurobiology · doi:10.1016/j.resp.2011.04.017 · Cited by 251
Self-citationGestational Hypoxia and Developmental Plasticity
Ducsay, C. A., Goyal, R., Pearce, W. J., Wilson, S. M., Hu, X., & Zhang, L. (2018) · Physiological Reviews · doi:10.1152/physrev.00043.2017 · Cited by 208
Measuring high-altitude adaptation
MOORE, L. G. (2017) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00321.2017 · Cited by 205
Self-citationAltitude Adaptation: A Glimpse Through Various Lenses
Simonson, T. S. (2015) · High Altitude Medicine & Biology · doi:10.1089/ham.2015.0033 · Cited by 181
Early life nutrition and metabolic programming
Fernandez‐Twinn, D. S., & Ozanne, S. E. (2010) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2010.05798.x · Cited by 180
Maternal Uterine Vascular Remodeling During Pregnancy
Osol, G., & MOORE, L. G. (2013) · Microcirculation · doi:10.1111/micc.12080 · Cited by 167
Self-citationGenomic insights into adaptation to high-altitude environments
Cheviron, Z. A., & Brumfield, R. T. (2011) · Heredity · doi:10.1038/hdy.2011.85 · Cited by 167
Maternal hemoglobin level and fetal outcome at low and high altitudes
Gonzales, G. F., Steenland, K., & Tapia, V. (2009) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00275.2009 · Cited by 162
Human Genetic Adaptation to High Altitude: Evidence from the Andes
Julian, C. G., & MOORE, L. G. (2019) · Genes · doi:10.3390/genes10020150 · Cited by 166
Self-citationAndean and Tibetan patterns of adaptation to high altitude
Bigham, A. W., Wilson, M. J., Julian, C. G., Kiyamu, M., Vargas, E., Lèon‐Velarde, F., Rivera, M. C., Rodriquez, C., Browne, V. A., Parra, E. J., et al. (2013) · American Journal of Human Biology · doi:10.1002/ajhb.22358 · Cited by 142
Self-citationHigh-Altitude Adaptation: Mechanistic Insights from Integrated Genomics and Physiology
Storz, J. F. (2021) · Molecular Biology and Evolution · doi:10.1093/molbev/msab064 · Cited by 140
Developmental Functional Adaptation to High Altitude: Review
Frisancho, A. R. (2013) · American Journal of Human Biology · doi:10.1002/ajhb.22367 · Cited by 141
Uterine artery blood flow, fetal hypoxia and fetal growth
Browne, V. A., Julian, C. G., Toledo-Jaldin, L., Cioffi-Ragan, D., Vargas, E., & Moore, L. G. (2015) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2014.0068 · Cited by 127
Self-citationPetousi, N., & Robbins, P. A. (2013) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00605.2013 · Cited by 127
Bigham, A. W., Julian, C. G., Wilson, M. J., Vargas, E., Browne, V. A., Shriver, M. D., & MOORE, L. G. (2014) · Physiological Genomics · doi:10.1152/physiolgenomics.00063.2014 · Cited by 114
Self-citationPreeclampsia link to gestational hypoxia
Tong, W., & Giussani, D. A. (2019) · Journal of Developmental Origins of Health and Disease · doi:10.1017/s204017441900014x · Cited by 121
Yung, H. W., Cox, M., van Patot, M. T., & Burton, G. J. (2012) · The FASEB Journal · doi:10.1096/fj.11-190082 · Cited by 112
Physiological Genomics of Adaptation to High-Altitude Hypoxia
Storz, J. F., & Cheviron, Z. A. (2020) · Annual Review of Animal Biosciences · doi:10.1146/annurev-animal-072820-102736 · Cited by 113
Evolutionary adaptation to high altitude: A view from in utero
Julian, C. G., Wilson, M. J., & MOORE, L. G. (2009) · American Journal of Human Biology · doi:10.1002/ajhb.20900 · Cited by 98
Self-citationHigh Altitude During Pregnancy
Julian, C. G. (2011) · Clinics in Chest Medicine · doi:10.1016/j.ccm.2010.10.008 · Cited by 94
Self-citationEpigenomics and human adaptation to high altitude
Julian, C. G. (2017) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00351.2017 · Cited by 78
Self-citationMatheson, H., Veerbeek, J. H. W., Charnock‐Jones, D. S., Burton, G. J., & Yung, H. W. (2016) · The Journal of Physiology · doi:10.1113/jp271073 · Cited by 71
Hypoxia, AMPK activation and uterine artery vasoreactivity
Skeffington, K. L., Higgins, J. S., Mahmoud, A. D., Evans, A. M., Sferruzzi‐Perri, A. N., Fowden, A. L., Yung, H. W., Burton, G. J., Giussani, D. A., & Moore, L. G. (2016) · The Journal of Physiology · doi:10.1113/jp270995 · Cited by 69
Self-citationPlacental Gas Exchange and the Oxygen Supply to the Fetus
Carter, A. M. (2015) · Comprehensive physiology · doi:10.1002/cphy.c140073 · Cited by 81
Browne, V. A., Toledo‐Jaldin, L., Davila, R. D., Lopez, L. P., Yamashiro, H., Cioffi‐Ragan, D., Julian, C. G., Wilson, M. J., Bigham, A. W., Shriver, M. D., et al. (2011) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.91046.2008 · Cited by 66
Self-citationInfluence of Estrogens on Uterine Vascular Adaptation in Normal and Preeclamptic Pregnancies
Mandalà, M. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21072592 · Cited by 65
Human genetic adaptation to high altitudes: Current status and future prospects
MOORE, L. G. (2016) · Quaternary International · doi:10.1016/j.quaint.2016.09.045 · Cited by 66
Self-citationPreeclampsia Link to Gestational Hypoxia
Tong, W., & Giussani, D. (2019) · Apollo (University of Cambridge) · doi:10.17863/cam.63245 · Cited by 59
MOORE, L. G. (2020) · Reproduction · doi:10.1530/rep-20-0349 · Cited by 57
Self-citationAn Argonaute 2 switch regulates circulating miR-210 to coordinate hypoxic adaptation across cells
Hale, A., Lee, C., Annis, S., Min, P., Pande, R. L., Creager, M. A., Julian, C. G., MOORE, L. G., Mitsialis, S. A., Hwang, S. J., et al. (2014) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2014.06.012 · Cited by 54
Self-citationThe impact of altitude on infant health in South America
Wehby, G. L., Castilla, E. E., & López‐Camelo, J. S. (2010) · Economics & Human Biology · doi:10.1016/j.ehb.2010.04.002 · Cited by 52
Maternal diet-induced obesity and offspring cardiovascular health
Blackmore, H. L., & Ozanne, S. E. (2013) · Journal of Developmental Origins of Health and Disease · doi:10.1017/s2040174412000761 · Cited by 46
Jean, D., & MOORE, L. G. (2012) · High Altitude Medicine & Biology · doi:10.1089/ham.2012.1021 · Cited by 43
Self-citationJulian, C. G., Hageman, J. L., Wilson, M. J., Vargas, E., & MOORE, L. G. (2011) · American Journal of Human Biology · doi:10.1002/ajhb.21167 · Cited by 42
Self-citationArishe, O. O., Ebeigbe, A. B., & Webb, R. C. (2019) · American Journal of Hypertension · doi:10.1093/ajh/hpz158 · Cited by 43
Guidelines for assessing maternal cardiovascular physiology during pregnancy and postpartum
Collins, H. E., Alexander, B. T., Care, A. S., Davenport, M. H., Davidge, S. T., Eghbali, M., Giussani, D. A., Hoes, M. F., Julian, C. G., LaVoie, H. A., et al. (2024) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00055.2024 · Cited by 46
Self-citationMaternal vascular responses to hypoxia in a rat model of intrauterine growth restriction
Aljunaidy, M. M., Morton, J. S., Cooke, C. M., & Davidge, S. T. (2016) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00119.2016 · Cited by 40
Niermeyer, S., Andrade‐M, M. P., Vargas, E., & MOORE, L. G. (2015) · Pulmonary Circulation · doi:10.1086/679719 · Cited by 37
Self-citationWhy is human uterine artery blood flow during pregnancy so high?
MOORE, L. G., Wesolowski, S. R., Lorca, R. A., Murray, A. J., & Julian, C. G. (2022) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00167.2022 · Cited by 36
Self-citationJulian, C. G., Vargas, E., Browne, V. A., Wilson, M. J., Bigham, A. W., Rodriguez, C., McCord, J. M., & MOORE, L. G. (2011) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2011.636102 · Cited by 34
Self-citationGonzales, G. F., Tapia, V., Gasco, M., & Carrillo, C. (2011) · The Journal of Maternal-Fetal & Neonatal Medicine · doi:10.3109/14767058.2011.623200 · Cited by 33
Pregnancy at high altitude in the Andes leads to increased total vessel density in healthy newborns
Gassmann, N. N., van Elteren, H. A., Goos, T. G., Morales, C. R., Rivera, M. C., Martín, D., Peralta, P. C., del Carpio, A. P., Machaca, S. A., Huicho, L., et al. (2016) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00561.2016 · Cited by 32
Šutovská, H. M., Babarikova, K., Zeman, M., & Molčan, Ľ. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23052885 · Cited by 37
High altitude regulates the expression of AMPK pathways in human placenta
Lorca, R. A., Houck, J. A., Laurent, L. C., Matarazzo, C. J., Baker, K., Horii, M., Nelson, K. K., Bales, E. S., Euser, A. G., Parast, M. M., et al. (2021) · Placenta · doi:10.1016/j.placenta.2021.01.010 · Cited by 32
Self-citationPreterm birth risk at high altitude in Peru
Levine, L. D., Gonzales, G. F., Tapia, V., Gasco, M., Sammel, M. D., Srinivas, S. K., & Ludmir, J. (2014) · American Journal of Obstetrics and Gynecology · doi:10.1016/j.ajog.2014.08.024 · Cited by 29
Developmental and genetic components explain enhanced pulmonary volumes of female peruvian quechua
Kiyamu, M., Bigham, A. W., Parra, E. J., Lèon‐Velarde, F., Rivera, M. C., & Brutsaert, T. D. (2012) · American Journal of Physical Anthropology · doi:10.1002/ajpa.22069 · Cited by 31
Self-citationCharles, S. M., Julian, C. G., Vargas, E., & Moore, L. G. (2014) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2013-4102 · Cited by 28
Self-citationMild anemia during pregnancy upregulates placental vascularity development
Stangret, A., Skoda, M., Wnuk, A., Pyźlak, M., & Szukiewicz, D. (2017) · Medical Hypotheses · doi:10.1016/j.mehy.2017.03.007 · Cited by 29
Lorca, R. A., Matarazzo, C. J., Bales, E. S., Houck, J. A., Orlicky, D. J., Euser, A. G., Julian, C. G., & MOORE, L. G. (2020) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00644.2019 · Cited by 27
Self-citationGonzales, G. F., Tapia, V., & Fort, A. L. (2012) · ISRN Obstetrics and Gynecology · doi:10.5402/2012/368571 · Cited by 27
High-altitude population neonatal and maternal phenotypes associated with birthweight protection
Dolma, P., Angchuk, P. T., Jain, V., Dadhwal, V., Kular, D., Williams, D. J., Montgomery, H., & Hillman, S. L. (2021) · Pediatric Research · doi:10.1038/s41390-021-01593-5 · Cited by 24
Time Domains of Hypoxia Responses and -Omics Insights
Yu, J. J., Non, A. L., Heinrich, E. C., Gu, W., Alcock, J., Moya, E. A., Lawrence, E. S., Tift, M. S., O’Brien, K. A., Storz, J. F., et al. (2022) · Frontiers in Physiology · doi:10.3389/fphys.2022.885295 · Cited by 29
Self-citationDavila, R. D., Julian, C. G., Wilson, M. J., Browne, V. A., Rodriguez, C., Bigham, A. W., Shriver, M. D., Vargas, E., & MOORE, L. G. (2010) · Reproductive Sciences · doi:10.1177/1933719110372418 · Cited by 25
Self-citationPregnancy increases myometrial artery myogenic tone via NOS- or COX-independent mechanisms
Eckman, D. M., Gupta, R., Rosenfeld, C. R., Morgan, T. M., Charles, S. M., Mertz, H., & MOORE, L. G. (2012) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00490.2011 · Cited by 25
Self-citationHeath-Freudenthal, A., Toledo-Jaldin, L., von Alvensleben, I., Lazo-Vega, L., Mizutani, R., Stalker, M., Yasini, H., Mendizábal, F., Madera, J. D., Mundo, W., et al. (2022) · Hypertension · doi:10.1161/hypertensionaha.122.19078 · Cited by 24
Self-citationNecesidades de investigación para el diagnóstico de anemia en poblaciones de altura
Gonzales, G. F., Fano-Sizgorich, D., & Vásquez‐Velásquez, C. (2017) · Revista Peruana de Medicina Experimental y Salud Pública · doi:10.17843/rpmesp.2017.344.3208 · Cited by 24
Effects of hypoxia on uteroplacental and fetoplacental vascular function during pregnancy
Arenas, G. A., & Lorca, R. A. (2024) · Frontiers in Physiology · doi:10.3389/fphys.2024.1490154 · Cited by 23
High Altitude Pregnancies and Vascular Dysfunction: Observations From Latin American Studies
González‐Candia, A., & Herrera, E. A. (2021) · Frontiers in Physiology · doi:10.3389/fphys.2021.786038 · Cited by 26
Heath‐Freudenthal, A., Toledo‐Jaldin, L., von Alvensleben, I., Lazo‐Vega, L., Mizutani, R., Stalker, M., Yasini, H., Mendizábal, F., Madera, J. D., Mundo, W., et al. (2022) · Apollo (University of Cambridge) · doi:10.17863/cam.97223 · Cited by 20
Self-citationPomeroy, E., Stock, J. T., Stanojevic, S., Miranda, J. J., Cole, T. J., & Wells, J. C. K. (2013) · American Journal of Human Biology · doi:10.1002/ajhb.22422 · Cited by 19
Cause of fetal growth restriction during high-altitude pregnancy
Brown, E. R., & Giussani, D. A. (2024) · iScience · doi:10.1016/j.isci.2024.109702 · Cited by 21
Robertson, C. E., & Wilsterman, K. (2020) · Journal of Experimental Biology · doi:10.1242/jeb.215350 · Cited by 21
Fetal growth, high altitude, and evolutionary adaptation: a new perspective
Wilsterman, K., & Cheviron, Z. A. (2021) · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology · doi:10.1152/ajpregu.00067.2021 · Cited by 19
Adaptation à l’hypoxie chronique des populations de haute altitude
Richalet, J. (2021) · Revue des Maladies Respiratoires · doi:10.1016/j.rmr.2020.11.007 · Cited by 20
Pomeroy, E., Wells, J. C. K., Stanojevic, S., Miranda, J. J., MOORE, L. G., Cole, T. J., & Stock, J. T. (2015) · American Journal of Human Biology · doi:10.1002/ajhb.22725 · Cited by 17
Self-citationDavila, R. D., Julian, C. G., Wilson, M. J., Browne, V. A., Rodriguez, C., Bigham, A. W., Shriver, M. D., Vargas, E., & MOORE, L. G. (2010) · Reproductive Sciences · doi:10.1177/1933719110380061 · Cited by 16
Self-citationFigueroa-Mujica, R., Ccahuantico, L. A., Ccorahua-Ríos, M. S., Sánchez-Huamán, J. J., Vásquez‐Velásquez, C., Ponce-Huarancca, J. M., Rozas-Gamarra, R. E., & Gonzales, G. F. (2022) · Life · doi:10.3390/life12050727 · Cited by 15
Hu, X., Dasgupta, C., Song, R., Romero, M., Wilson, S. M., & Zhang, L. (2021) · Hypertension · doi:10.1161/hypertensionaha.120.16831 · Cited by 15
Impacto de la altura en el embarazo y en el producto de la gestación
Gonzales, G. F. (2012) · Revista Peruana de Medicina Experimental y Salud Pública · doi:10.1590/s1726-46342012000200013 · Cited by 20
Neonatal Variables, Altitude of Residence and Aymara Ancestry in Northern Chile
Rothhammer, F., Fuentes‐Guajardo, M., Chakraborty, R., Bermejo, J. L., & Dittmar, M. (2015) · PLoS ONE · doi:10.1371/journal.pone.0121834 · Cited by 16
Doppler Assessment of Uterine Blood Flow in Pre-eclampsia: A Review
Kane, S. C., & Dennis, A. T. (2015) · Hypertension in Pregnancy · doi:10.3109/10641955.2015.1074244 · Cited by 14
Julian, C. G., Yang, I. V., Browne, V. A., Vargas, E., Rodriguez, C., Pedersen, B. S., MOORE, L. G., & Schwartz, D. A. (2013) · The FASEB Journal · doi:10.1096/fj.13-239749 · Cited by 14
Self-citationWolfson, G. H., Vargas, E., Browne, V. A., MOORE, L. G., & Julian, C. G. (2016) · The Journal of Clinical Endocrinology & Metabolism · doi:10.1210/jc.2016-1767 · Cited by 14
Self-citationSeifu, W. D., Bekele‐Alemu, A., & Zeng, C. (2025) · Frontiers in Genetics · doi:10.3389/fgene.2024.1510932 · Cited by 15
O’Brien, K. A., Gu, W., Houck, J. A., Holzner, L. M. W., Yung, H. W., Armstrong, J. L., Sowton, A. P., Baxter, R. M., Darwin, P. M., Toledo‐Jaldin, L., et al. (2023) · Hypertension · doi:10.1161/hypertensionaha.123.21748 · Cited by 14
Self-citationHufnagel, A., Grant, I. D., & Aiken, C. (2022) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2022.03.041 · Cited by 13
Gas Exchange across the Placenta
Saini, B. S., Morrison, J. L., & Seed, M. (2020) · Cambridge University Press eBooks · doi:10.1017/9781108163705.005 · Cited by 14
Altered placental ion channel gene expression in preeclamptic high-altitude pregnancies
Julian, C. G., Houck, J. A., Fallahi, S., Lazo‐Vega, L., Matarazzo, C. J., Diamond, B., Miranda‐Garrido, V., Krause, B. J., MOORE, L. G., Shortt, J., et al. (2023) · Physiological Genomics · doi:10.1152/physiolgenomics.00013.2023 · Cited by 12
Self-citationSurviving birth at high altitude
Heath‐Freudenthal, A., Estrada, A., von Alvensleben, I., & Julian, C. G. (2024) · The Journal of Physiology · doi:10.1113/jp284554 · Cited by 12
Self-citationMOORE, L. G., Lorca, R. A., Gumina, D. L., Wesolowski, S. R., Reisz, J. A., Cioffi‐Ragan, D., Houck, J. A., Banerji, S., Euser, A. G., D’Alessandro, A., et al. (2024) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00193.2024 · Cited by 11
Self-citationAksoy, A. N., Batmaz, G., Dane, B., Kucur, S. K., & Gözükara, İ. (2015) · Journal of the Turkish-German Gynecological Association · doi:10.5152/jtgga.2015.15134 · Cited by 11
Parental ancestry and risk of early pregnancy loss at high altitude
Grant, I. D., Soria, R., Julian, C. G., Vargas, E., MOORE, L. G., Aiken, C., & Giussani, D. A. (2020) · The FASEB Journal · doi:10.1096/fj.202001257r · Cited by 11
Self-citationThe Human Embryo and Its Environment: In Utero Challenges and Physiological Outcomes
Hutter, D. (2018) · Springer eBooks · doi:10.1007/978-3-319-75935-7_16 · Cited by 10
Uterine blood flow as a determinant of fetoplacental development
Moore, L. G. (2010) · The Placenta and Human Developmental Programming · doi:10.1017/cbo9780511933806.012 · Cited by 9
Self-citationXu, S., Wang, W., Li, Q., Huang, L. S., Chen, X., Zhang, X., Wang, X., Han, W., Hu, X., Yang, X., et al. (2022) · Nutrients · doi:10.3390/nu14071403 · Cited by 9
Genetic adaptations shaping survival, pregnancy, and life at high altitude and sea level
Gu, W., Lawrence, E. S., Evans, A. M., & Simonson, T. S. (2025) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2024.0170 · Cited by 8
How hypoxia slows fetal growth: insights from high altitude
MOORE, L. G. (2021) · Pediatric Research · doi:10.1038/s41390-021-01784-0 · Cited by 8
Self-citationPESO AL NACER EN RECIÉN NACIDOS A TÉRMINO EN DIFERENTES NIVELES DE ALTURA EN EL PERÚ
Villamonte, W., Jerí-Palomino, M., Lajo, L., Monteagudo, Y. V., & Diez, G. (2015) · Revista Peruana de Ginecología y Obstetricia · doi:10.31403/rpgo.v57i178 · Cited by 8
Niermeyer, S. (2013) · Springer eBooks · doi:10.1007/978-1-4614-8772-2_18 · Cited by 8
SIMÓ, C., & Méndez, S. (2013) · Journal of Biosocial Science · doi:10.1017/s0021932013000539 · Cited by 7
Uteroplacental Ischemia Is Associated with Increased PAPP-A2
Lamale‐Smith, L. M., Gumina, D. L., Kramer, A. W., Browne, V. A., Toledo‐Jaldin, L., Julian, C. G., Winn, V. D., & MOORE, L. G. (2020) · Reproductive Sciences · doi:10.1007/s43032-019-00050-3 · Cited by 7
Self-citationWiegel, R. E., Baker, K., Toledo, C. C., Gomez, R., Gutiérrez-Cortez, S., Houck, J. A., Larrea, A., Lazo‐Vega, L., MOORE, L. G., Pisc, J. A., et al. (2024) · American Journal of Physiology-Heart and Circulatory Physiology · doi:10.1152/ajpheart.00520.2024 · Cited by 6
Self-citationPiezo1 channels mediate vasorelaxation of uterine arteries from pseudopregnant rats
Arishe, O. O., McKenzie, J., Justina, V. D., Moraes, R. D. A., Webb, R. C., & Priviero, F. B. M. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1140989 · Cited by 6
Metadata
- Authors
- Julian, C. G., Wilson, M. J., Lopez, M., Yamashiro, H., Tellez, W., Rodriguez, A., Bigham, A. W., Shriver, M. D., Rodriguez, C., Vargas, E., & Moore, L. G.
- Affiliations
- University of Colorado Denver (US)
- Pennsylvania State University (US)
- Universidad Mayor de San Andrés (BO)
- Wake Forest University (US)
- ORCID
- Venue
- American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
- Publisher
- American Physiological Society
- Published
- 2009-05
- Volume
- 296
- Issue
- 5
- Pages
- R1564-R1575
- ISSN
- 0363-6119 (ISSN-L)
- 1522-1490
- PMC
- PMC2689835
- OpenAlex
- W2139645408
- Cited by
- 141
- References
- 36
- Citations by year
- 2026: 5 · 2025: 13 · 2024: 8 · 2023: 5 · 2022: 11 · 2021: 9 · 2020: 9 · 2019: 6 · 2018: 4 · 2017: 6 · 2016: 5 · 2015: 15 · 2014: 5 · 2013: 13 · 2012: 8
- FWCI
- 5.26
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- American Journal of Physiology-Regulatory, Integrative and Comparative Physiology (publishedVersion)
- Europe PMC (PubMed Central) (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- U.S. Public Health Service (HLBI-079647, HLBI-60131)
- Fogarty International Center (TW 01188, R03TW007957, R03TW001188)
- Topics
- Health Sciences › Medicine › Physiology (medical) › High Altitude and Hypoxia
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Birth, Development, and Health
- Keywords
- uterine artery blood flow, fetal growth, high altitude, birth weight, fetal oxygen delivery, hypoxia, fetal biometry, fetal head circumference, Indigenous American ancestry, maternal ancestry, pregnancy, Doppler ultrasound
- MeSH terms
- Adult, Altitude, Arteries, Biological Transport, Birth Weight, Bolivia, Europe, Female, Humans, Oxygen, Pregnancy, Regional Blood Flow, Uterus, Case-Control Studies, White People, American Indian or Alaska Native, Fetal Development
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
