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Cited by 425

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Relation of volume history of lungs to respiratory mechanics in anesthetized dogs

Mead, Jere, Collier, Clarence·1959·Journal of Applied Physiology

Abstract

When anesthetized dogs were allowed to breathe spontaneously or were paralyzed and ventilated in the resting tidal range by means of a pump, pulmonary compliance fell progressively. These changes were immediately reversed following forced inflations of the lungs, while forced deflations caused further compliance reductions. The appearance of the lungs post mortem suggested that closure of air-spaces was at least in part responsible for the compliance reductions. Evidence from measurements of total and ventilatory lung gas volumes indicated that the closed spaces were essentially atelectatic. These findings have been related to other observations made in experimental animals and in man. Submitted on December 29, 1958

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Metadata

Authors
Mead, J., & Collier, C.
Venue
Journal of Applied Physiology
Published
1959-09-01
Volume
14
Issue
5
Pages
669-678
ISSN
  • 0161-7567 (ISSN-L)
  • 8750-7587
  • 1522-1601
OpenAlex
W2174918665
Cited by
425
References
0
FWCI
11.88
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Relation of volume history of lungs to respiratory mechanics in anesthetized dogs. https://app.cochat.ai/papers/10.1152/jappl.1959.14.5.669
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Mead, J., & Collier, C. (1959). Relation of volume history of lungs to respiratory mechanics in anesthetized dogs. Journal of Applied Physiology. https://doi.org/10.1152/jappl.1959.14.5.669

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