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Cited by 37Muscle metabolism and nutritionThermoregulation and physiological responsesCardiovascular and exercise physiology

Hypohydration does not impair skeletal muscle glycogen resynthesis after exercise

Neufer, P. D., Sawka, M. N., Young, A. J., Quigley, M. D., Latzka, W. A., Levine, L.·1991·Journal of Applied Physiology
DOI 10.1152/jappl.1991.70.4.1490
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Abstract

The purpose of this investigation was to examine the effects of moderate hypohydration (HY) on skeletal muscle glycogen resynthesis after exhaustive exercise. On two occasions, eight males completed 2 h of intermittent cycle ergometer exercise (4 bouts of 17 min at 60% and 3 min at 80% of maximal O2 consumption/10 min rest) to reduce muscle glycogen concentrations (control values 711 +/- 41 mumol/g dry wt). During one trial, cycle exercise was followed by several hours of light upper body exercise in the heat without fluid replacement to induce HY (-5% body wt); in the second trial, sufficient water was ingested during the upper body exercise and heat exposure to maintain euhydration (EU). In both trials, 400 g of carbohydrate were ingested at the completion of exercise and followed by 15 h of rest while the desired hydration level was maintained. Muscle biopsy samples were obtained from the vastus lateralis immediately after intermittent cycle exercise (T1) and after 15 h of rest (T2). During the HY trial, the muscle water content was lower (P less than 0.05) at T1 and T2 (288 +/- 9 and 265 +/- 5 ml/100 g dry wt, respectively; NS) than during EU (313 +/- 8 and 301 +/- 4 ml/100 g dry wt, respectively; NS). Muscle glycogen concentration was not significantly different during EU and HY at T1 (200 +/- 35 vs. 251 +/- 50 mumol/g dry wt) or T2 (452 +/- 34 vs. 491 +/- 35 mumol/g dry wt). These data indicate that, despite reduced water content during the first 15 h after heavy exercise, skeletal muscle glycogen resynthesis is not impaired.

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Crossref · 10.1152/jappl.1991.70.4.1490

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  • Dehydration equivalent to loss of ~5% BM or 8% body water does not interfere with glycogen storage during 15 h following cycling exercise.

    “This study found that dehydration equivalent to loss of ~5% BM or 8% body water did not interfere with glycogen storage during 15 h following cycling exercise, although muscle water content was lower than in the trial involving euhydrated recovery.”

    From Postexercise muscle glycogen resynthesis in humans. (2017) · cites this paper as [72]

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Authors
Neufer, P. D., Sawka, M. N., Young, A. J., Quigley, M. D., Latzka, W. A., & Levine, L.
Affiliations
U.S. Army Research Institute of Environmental Medicine (US)
ORCID
Venue
Journal of Applied Physiology
Publisher
American Physiological Society
Published
1991-04-01
Volume
70
Issue
4
Pages
1490-1494
ISSN
  • 0161-7567 (ISSN-L)
  • 8750-7587
  • 1522-1601
DOI
10.1152/jappl.1991.70.4.1490
OpenAlex
W1805398143
Cited by
37
References
1
Citations by year
2025: 2 · 2024: 1 · 2023: 1 · 2021: 1 · 2019: 2 · 2018: 1 · 2016: 3 · 2015: 4 · 2014: 2 · 2013: 1 · 2012: 1
FWCI
0.15
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Applied Physiology (publishedVersion)
  • PubMed (publishedVersion)
  • Defense Technical Information Center (DTIC) (submittedVersion)
Topics
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Cell Biology › Muscle metabolism and nutrition
  • Health Sciences › Medicine › Physiology › Thermoregulation and physiological responses
  • Health Sciences › Medicine › Complementary and alternative medicine › Cardiovascular and exercise physiology
Keywords
hypohydration, post-exercise recovery, carbohydrate intake, muscle water content, heat exposure, fluid replacement, exercise dehydration, vastus lateralis
MeSH terms
Adolescent, Adult, Body Water, Dehydration, Dietary Carbohydrates, Glycogen, Humans, Male, Muscles, Oxygen Consumption, Sweating, Exercise

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