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Time course of glycogen accumulation after eccentric exercise
Abstract
This study examined the time course of glycogen accumulation in skeletal muscle depleted by concentric work and subsequently subjected to eccentric exercise. Eight men exercised to exhaustion on a cycle ergometer [70% of maximal O2 consumption (VO2max)] and were placed on a carbohydrate-restricted diet. Approximately 12 h later they exercised one leg to subjective failure by repeated eccentric action of the knee extensors against a resistance equal to 120% of their one-repetition maximum concentric knee extension force (ECC leg). The contralateral leg was not exercised and served as a control (CON leg). During the 72-h recovery period, subjects consumed 7 g carbohydrate.kg body wt-1.day-1. Moderate soreness was experienced in the ECC leg 24–72 h after eccentric exercise. Muscle biopsies from the vastus lateralis of the ECC and CON legs revealed similar glycogen levels immediately after eccentric exercise (40.2 +/- 5.2 and 47.6 +/- 6.4 mmol/kg wet wt, respectively; P greater than 0.05). There was no difference in the glycogen content of ECC and CON legs after 6 h of recovery (77.7 +/- 7.9 and 85.1 +/- 4.9 mmol/kg wet wt, respectively; P greater than 0.05), but 18 h later, the ECC leg contained 15% less glycogen than the CON leg (90.2 +/- 8.2 vs. 105.8 +/- 8.9 mmol/kg wet wt; P less than 0.05). After 72 h of recovery, this difference had increased to 24% (115.8 +/- 8.0 vs. 153.0 +/- 12.2 mmol/kg wet wt; P less than 0.05). These data confirm that glycogen accumulation is impaired in eccentrically exercised muscle.(ABSTRACT TRUNCATED AT 250 WORDS)
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The reduction in muscle glycogen restoration after eccentric exercise or exhaustive running does not occur in the early phase (0-6 h) of recovery but is associated with later recovery.
“with a time course suggesting that this phenomenon did not occur in the early phase (0-6 h) of recovery but was associated with later recovery (114).”
From Postexercise muscle glycogen resynthesis in humans. (2017) · cites this paper as [114]
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“recovery, with a time course suggesting that this phenomenon did not occur in the early phase (0–6 h) of recovery but was associated with later recovery (114).”
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Metadata
- Authors
- Widrick, J. J., Costill, D. L., McConell, G. K., Anderson, D. E., Pearson, D. R., & Zachwieja, J. J.
- Affiliations
- Ball State University (US)
- Venue
- Journal of Applied Physiology
- Publisher
- American Physiological Society
- Published
- 1992-05-01
- Volume
- 72
- Issue
- 5
- Pages
- 1999-2004
- ISSN
- 0161-7567 (ISSN-L)
- 8750-7587
- 1522-1601
- OpenAlex
- W2209536738
- Cited by
- 60
- References
- 0
- Citations by year
- 2025: 1 · 2023: 1 · 2022: 2 · 2021: 1 · 2020: 6 · 2018: 3 · 2017: 1 · 2016: 1 · 2015: 3 · 2014: 4 · 2013: 2 · 2012: 3
- FWCI
- 1.70
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Applied Physiology (publishedVersion)
- PubMed (publishedVersion)
- Victoria University Research Repository (Victoria University) (submittedVersion)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Exercise and Physiological Responses
- Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
- Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
- Keywords
- skeletal muscle glycogen, glycogen accumulation, eccentric exercise, muscle glycogen depletion, post-exercise recovery, vastus lateralis, low-carbohydrate diet, exercise-induced muscle pain, knee extensors
- MeSH terms
- Adult, Dietary Carbohydrates, Glycogen, Humans, Male, Muscles, Time Factors, Exercise
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