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In vivo validation of whole body composition estimates from dual-energy X-ray absorptiometry
Abstract
Prior, Barry M., Kirk J. Cureton, Christopher M. Modlesky, Ellen M. Evans, Mark A. Sloniger, Michael Saunders, and Richard D. Lewis. In vivo validation of whole body composition estimates from dual-energy X-ray absorptiometry. J. Appl. Physiol. 83(2): 623–630, 1997.—We validated whole body composition estimates from dual-energy X-ray absorptiometry (DEXA) against estimates from a four-component model to determine whether accuracy is affected by gender, race, athletic status, or musculoskeletal development in young adults. Measurements of body density by hydrostatic weighing, body water by deuterium dilution, and bone mineral by whole body DEXA were obtained in 172 young men ( n = 91) and women ( n = 81). Estimates of body fat (%Fat) from DEXA (%Fat DEXA) were highly correlated with estimates of body fat from the four-component model [body density, total body water, and total body mineral (%Fat d,w,m); r = 0.94, standard error of the estimante (SEE) = 2.8% body mass (BM)] with no significant difference between methods [mean of the difference ± SD of the difference = −0.4 ± 2.9 (SD) % BM, P = 0.10] in women and men. On the basis of the comparison with %Fat d,w,m, estimates of %Fat DEXA were slightly more accurate than those from body density ( r = 0.91, SEE = 3.4%; mean of the difference ± SD of the difference = −1.2 ± 3.4% BM). Differences between %Fat DEXA and %Fat d,w,m were weakly related to body thickness, as reflected by BMI ( r= −0.34), and to the percentage of water in the fat-free mass ( r = −0.51), but were not affected by race, athletic status, or musculoskeletal development. We conclude that body composition estimates from DEXA are accurate compared with those from a four-component model in young adults who vary in gender, race, athletic status, body size, musculoskeletal development, and body fatness.
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“Estimates of %BF are also accurate (11)(12)(13), but values can differ based on the DXA instrumentation utilized (e.g., Lunar, Hologic, Norland).”
From Comparison of Body Composition Methods in Obese African‐American Women (2006) · cites this paper as [13]
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Metadata
- Authors
- Prior, B. M., Cureton, K. J., Modlesky, C. M., Evans, E. M., Sloniger, M. A., Saunders, M., & Lewis, R. D.
- Affiliations
- University of Georgia (US)
- Venue
- Journal of Applied Physiology
- Publisher
- American Physiological Society
- Published
- 1997-08-01
- Volume
- 83
- Issue
- 2
- Pages
- 623-630
- ISSN
- 0161-7567 (ISSN-L)
- 8750-7587
- 1522-1601
- OpenAlex
- W2160364007
- Cited by
- 317
- References
- 33
- Citations by year
- 2026: 4 · 2025: 5 · 2024: 10 · 2023: 8 · 2022: 10 · 2021: 14 · 2020: 10 · 2019: 5 · 2018: 13 · 2017: 11 · 2016: 12 · 2015: 7 · 2014: 20 · 2013: 13 · 2012: 17
- FWCI
- 4.24
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Journal of Applied Physiology (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Physiology (medical) › Body Composition Measurement Techniques
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Health Sciences › Medicine › Infectious Diseases › HIV-related health complications and treatments
- Keywords
- dual-energy X-ray absorptiometry, body composition, four-component model, body fat percentage, body density, hydrostatic weighing, deuterium dilution, bone mineral, young adults, method validation, body mass index, athletic status, musculoskeletal development, sex differences
- MeSH terms
- Adipose Tissue, Adult, Body Composition, Body Water, Body Weight, Female, Humans, Male, Minerals, Models, Biological, Absorptiometry, Photon
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