The DOI matches its Crossref record; 5 of the 5 references it cites were found in a registry or an index.
Is there evidence for an age-related reduction in metabolic rate?
Abstract
To determine whether the age-related reduction in basal metabolic rate (BMR) is explained by a quantitative and/or qualitative change in the components of lean tissue, we conducted a cross-sectional study in groups of young ( n = 38, 18–35 yr) and older ( n = 24, 50–77 yr) healthy individuals. BMR was measured by indirect calorimetry. Body composition was obtained by using dual-energy X-ray absorptiometry (DEXA), which permitted four compartments to be quantified [bone mineral mass, fat mass (FM), appendicular lean tissue mass (A LTM), and nonappendicular lean tissue mass (NA LTM)]. Absolute BMR and A LTM were lower, whereas FM was significantly higher in the older, compared with young, subjects. BMR, adjusted for differences in FM, A LTM, and NA LTM,was significantly lower in the older subjects by 644 kJ/day. In separate regression analyses of BMR on body compartments, older subjects had significantly lower regression coefficients for A LTM and NA LTM, compared with young subjects. Hence, the age-related decline in BMR is partly explained by a reduction in the quantity, as well as the metabolic activity, of DEXA-derived lean tissue components.
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Svendsen, O. L., Hassager, C., & Christiansen, C. (1993) · Metabolism · doi:10.1016/0026-0495(93)90155-h · Cited by 62
Cited by
Review Article: Sarcopenia: Causes, Consequences, and Preventions
Marcell, T. J. (2003) · The Journals of Gerontology Series A: Biological Sciences and Medical Sciences · doi:10.1093/gerona/58.10.m911 · Cited by 536
Johnstone, A. M., Murison, S. D., Duncan, J. S., Rance, K. A., & Speakman, J. R. (2005) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/82.5.941 · Cited by 514
Age and aerobic exercise training effects on whole body and muscle protein metabolism
Short, K. R., Vittone, J. L., Bigelow, M. L., Proctor, D. N., & Nair, K. S. (2004) · American Journal of Physiology-Endocrinology and Metabolism · doi:10.1152/ajpendo.00366.2003 · Cited by 470
Current Status of the Diagnosis and Management of Osteoporosis
Aibar-Almazán, A., Voltes-Martínez, A., Castellote-Caballero, Y., Afanador-Restrepo, D. F., Carcelén-Fraile, M. D. C., & López-Ruiz, E. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms23169465 · Cited by 412
Rees, D., Miles, E. A., Banerjee, T., Wells, S. J., Roynette, C. E., Wahle, K. W., & Calder, P. C. (2006) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/83.2.331 · Cited by 401
Metadata
- Authors
- Piers, L. S., Soares, M. J., McCormack, L. M., & O’Dea, K.
- Venue
- Journal of Applied Physiology
- Publisher
- American Physiological Society
- Published
- 1998-12-01
- Volume
- 85
- Issue
- 6
- Pages
- 2196-2204
- ISSN
- 0161-7567 (ISSN-L)
- 8750-7587
- 1522-1601
- OpenAlex
- W98817010
- Cited by
- 189
- References
- 5
- FWCI
- 2.41
- Type
- journal article
- Language
- en
- Open access
- closed
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- CoChat. (2026). Citation check: Is there evidence for an age-related reduction in metabolic rate? https://app.cochat.ai/papers/10.1152/jappl.1998.85.6.2196
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- Piers, L. S., Soares, M. J., McCormack, L. M., & O’Dea, K. (1998). Is there evidence for an age-related reduction in metabolic rate? Journal of Applied Physiology. https://doi.org/10.1152/jappl.1998.85.6.2196
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
