The DOI matches its Crossref record; 95 of the 95 references it cites were found in a registry or an index.
Locomotor activity in spinal cord-injured persons
Abstract
After a spinal cord injury (SCI) of the cat or rat, neuronal centers below the level of lesion exhibit plasticity that can be exploited by specific training paradigms. In individuals with complete or incomplete SCI, human spinal locomotor centers can be activated and modulated by locomotor training (facilitating stepping movements of the legs using body weight support on a treadmill to provide appropriate sensory cues). Individuals with incomplete SCI benefit from locomotor training such that they improve their ability to walk over ground. Load- or hip joint-related afferent input seems to be of crucial importance for both the generation of a locomotor pattern and the effectiveness of the training. However, it may be a critical combination of afferent signals that is needed to generate a locomotor pattern after severe SCI. Mobility of individuals after a SCI can be improved by taking advantage of the plasticity of the central nervous system and can be maintained with persistent locomotor activity. In the future, if regeneration approaches can successfully be applied in human SCI, even individuals with complete SCI may recover walking ability with locomotor training.
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Cites
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Self-citationHuman Lumbosacral Spinal Cord Interprets Loading During Stepping
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Self-citationLocomotor Training After Human Spinal Cord Injury: A Series of Case Studies
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Cited by
Kinematic Design to Improve Ergonomics in Human Machine Interaction
Schiele, A., & van der Helm, F. C. T. (2006) · IEEE Transactions on Neural Systems and Rehabilitation Engineering · doi:10.1109/tnsre.2006.881565 · Cited by 386
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Muscle proprioceptive feedback and spinal networks
Windhorst, U. (2007) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2007.03.010 · Cited by 324
Recovery of Locomotion After Spinal Cord Injury: Some Facts and Mechanisms
Rossignol, S., & Frigon, A. (2011) · Annual Review of Neuroscience · doi:10.1146/annurev-neuro-061010-113746 · Cited by 320
Metadata
- Authors
- Dietz, V., & Harkema, S. J.
- Venue
- Journal of Applied Physiology
- Publisher
- American Physiological Society
- Published
- 2004-05
- Volume
- 96
- Issue
- 5
- Pages
- 1954-1960
- ISSN
- 0161-7567 (ISSN-L)
- 8750-7587
- 1522-1601
- OpenAlex
- W2122715731
- Cited by
- 351
- References
- 95
- FWCI
- 13.95
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
