The DOI matches its Crossref record; 9 of the 9 references it cites were found in a registry or an index.
Sex differences in human skeletal muscle fatigue are eliminated under ischemic conditions
Abstract
Several studies have suggested that women may be more resistant to muscle fatigue than men (Fulco CS, Rock PB, Muza SA, Lammi E, Cymerman A, Butterfield G, Moore, LG, Braun B, and Lewis SF. Acta Physiol Scand 167: 233–239, 1999) possibly because of differences in muscle oxidative metabolism. We evaluated muscle fatigue produced by intermittent, maximal volitional isometric contractions of the dorsiflexor muscles of healthy young (21–34 yr) men ( n = 8) and women ( n = 8) under two conditions: free-flow (FF) circulation and ischemia. Measures of voluntary and stimulated (10- and 50-Hz) force, central activation ratio (CAR), and compound muscle action potential (CMAP) were collected in each session. The ischemic protocol induced greater fatigue than the FF protocol, in both sexes, and was associated with greater reductions in CAR, CMAP, stimulated force, and the ratio of 10- to 50-Hz force compared with the FF condition. Women fatigued less than men in FF but not during ischemia, and this difference was roughly paralleled by a difference in CAR. No sex effects on the CMAP, tetanic force, and measures of excitation-contraction coupling function were found in the FF condition, suggesting that the primary mechanism behind the difference in fatigue was a relatively greater impairment of central activation in men. The observation that ischemia eliminated the sex differences in fatigue is consistent with a number of studies (Kent-Braun JA, Ng AV, Doyle JW, and Towse TF. J Appl Physiol93: 1813–1823, 2002) relating fatigue to muscle metabolism and might be the result of sex-based differences in metabolic pathway utilization during muscle contraction.
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PHYSICAL ACTIVITY ASSESSMENT METHODOLOGY IN THE FIVE-CITY PROJECT1
SALLIS, J. F., HASKELL, W. L., WOOD, P. D., FORTMANN, S. P., ROGERS, T., BLAIR, S. N., & PAFFENBARGER, R. S. (1985) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a113987 · Cited by 1,716
Cellular mechanisms of muscle fatigue
Fitts, R. H. (1994) · Physiological Reviews · doi:10.1152/physrev.1994.74.1.49 · Cited by 1,537
Motor unit firing rates and contractile properties in tibialis anterior of young and old men
Connelly, D. M., Rice, C. L., Roos, M. R., & Vandervoort, A. A. (1999) · Journal of Applied Physiology · doi:10.1152/jappl.1999.87.2.843 · Cited by 340
Metabolic response in type I and type II muscle fibers during a 30-s cycle sprint in men and women
Esbjörnsson-Liljedahl, M., Sundberg, C. J., Norman, B., & Jansson, E. (1999) · Journal of Applied Physiology · doi:10.1152/jappl.1999.87.4.1326 · Cited by 199
Fulco, Rock, Muza, Lammi, Cymerman, Butterfield, Moore, Braun, & Lewis (1999) · Acta Physiologica Scandinavica · doi:10.1046/j.1365-201x.1999.00613.x · Cited by 192
Muscle metabolites and performance during high-intensity, intermittent exercise
Hargreaves, M., McKenna, M. J., Jenkins, D. G., Warmington, S. A., Li, J. L., Snow, R. J., & Febbraio, M. A. (1998) · Journal of Applied Physiology · doi:10.1152/jappl.1998.84.5.1687 · Cited by 173
Male and female differences in enzyme activities of energy metabolism in vastus lateralis muscle
Green, H. J., Fraser, I. G., & Ranney, D. A. (1984) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(84)90095-9 · Cited by 157
Jaworowski, Å., Porter, M. M., Holmbäck, A. M., Downham, D., & Lexell, J. (2002) · Acta Physiologica Scandinavica · doi:10.1046/j.1365-201x.2002.t01-2-01004.x · Cited by 104
Rate of tension development in isometric contractions of a human hand muscle
Miller, R. G., Mirka, A., & Maxfield, M. (1981) · Experimental Neurology · doi:10.1016/0014-4886(81)90061-3 · Cited by 65
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HUNTER, S. K., S. ANGADI, S., BHARGAVA, A., HARPER, J., HIRSCHBERG, A. L., D. LEVINE, B., L. MOREAU, K., J. NOKOFF, N., STACHENFELD, N. S., & BERMON, S. (2023) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000003300 · Cited by 241
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Billaut, F., & Bishop, D. (2009) · Sports Medicine · doi:10.2165/00007256-200939040-00001 · Cited by 169
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Fragala, M. S., Kraemer, W. J., Denegar, C. R., Maresh, C. M., Mastro, A. M., & Volek, J. S. (2011) · Sports Medicine · doi:10.2165/11590430-000000000-00000 · Cited by 145
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Hunter, S. K., Critchlow, A., & Enoka, R. M. (2004) · Journal of Applied Physiology · doi:10.1152/japplphysiol.00460.2004 · Cited by 136
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Clark, B. C., Cook, S. B., & Ploutz-Snyder, L. L. (2007) · Journal of Electromyography and Kinesiology · doi:10.1016/j.jelekin.2005.11.008 · Cited by 107
Hunter, S. K., Angadi, S. S., Bhargava, A., Harper, J., Hirschberg, A. L., Levine, B. D., Moreau, K. L., Nokoff, N. J., Stachenfeld, N. S., & Bermon, S. (2023) · Translational Journal of the American College of Sports Medicine · doi:10.1249/tjx.0000000000000236 · Cited by 43
Keller, J. L., Housh, T. J., Hill, E. C., Smith, C. M., Schmidt, R. J., & Johnson, G. O. (2019) · Applied Psychophysiology and Biofeedback · doi:10.1007/s10484-019-09450-2 · Cited by 22
The Effect of Creatine Loading on Neuromuscular Fatigue in Women
SMITH-RYAN, A. E., RYAN, E. D., FUKUDA, D. H., COSTA, P. B., CRAMER, J. T., & STOUT, J. R. (2014) · Medicine & Science in Sports & Exercise · doi:10.1249/mss.0000000000000194 · Cited by 8
Metadata
- Authors
- Russ, D. W., & Kent-Braun, J. A.
- Venue
- Journal of Applied Physiology
- Publisher
- American Physiological Society
- Published
- 2003-06-01
- Volume
- 94
- Issue
- 6
- Pages
- 2414-2422
- ISSN
- 0161-7567 (ISSN-L)
- 8750-7587
- 1522-1601
- OpenAlex
- W1973883641
- Cited by
- 259
- References
- 9
- FWCI
- 7.94
- Type
- journal article
- Language
- en
- Open access
- closed
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