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Cited by 137Sports Performance and TrainingCardiovascular and exercise physiologyMuscle metabolism and nutrition

The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.

Effects of chronic NaHCO3 ingestion during interval training on changes to muscle buffer capacity, metabolism, and short-term endurance performance

Edge, Johann, Bishop, David, Goodman, Carmel·2006·Journal of Applied Physiology
DOI 10.1152/japplphysiol.01534.2005
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Abstract

This study determined the effects of altering the H+ concentration during interval training, by ingesting NaHCO 3 (Alk-T) or a placebo (Pla-T), on changes in muscle buffer capacity (βm), endurance performance, and muscle metabolites. Pre- and posttraining peak O 2 uptake (V̇o 2 peak), lactate threshold (LT), and time to fatigue at 100% pretraining V̇o 2 peak intensity were assessed in 16 recreationally active women. Subjects were matched on the LT, were randomly placed into the Alk-T ( n = 8) or Pla-T ( n = 8) groups, and performed 8 wk (3 days/wk) of six to twelve 2-min cycle intervals at 140–170% of their LT, ingesting NaHCO 3 or a placebo before each training session (work matched between groups). Both groups had improvements in βm (19 vs. 9%; P < 0.05) and V̇o 2 peak (22 vs. 17%; P < 0.05) after the training period, with no differences between groups. There was a significant correlation between pretraining βm and percent change in βm ( r = −0.70, P < 0.05). There were greater improvements in both the LT (26 vs. 15%; P = 0.05) and time to fatigue (164 vs. 123%; P = 0.05) after Alk-T, compared with Pla-T. There were no changes to pre- or postexercise ATP, phosphocreatine, creatine, and intracellular lactate concentrations, or pH i after training. Our findings suggest that training intensity, rather than the accumulation of H+ during training, may be more important to improvements in βm. The group ingesting NaHCO 3 before each training session had larger improvements in the LT and endurance performance, possibly because of a reduced metabolic acidosis during training and a greater improvement in muscle oxidative capacity.

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Crossref · 10.1152/japplphysiol.01534.2005

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Metadata

Authors
Edge, J., Bishop, D., & Goodman, C.
Affiliations
The University of Western Australia (AU)
ORCID
Bishop, David
Venue
Journal of Applied Physiology
Publisher
American Physiological Society
Published
2006-09
Volume
101
Issue
3
Pages
918-925
ISSN
  • 0161-7567 (ISSN-L)
  • 8750-7587
  • 1522-1601
DOI
10.1152/japplphysiol.01534.2005
OpenAlex
W2007237261
Cited by
137
References
48
Citations by year
2026: 5 · 2025: 7 · 2024: 3 · 2023: 7 · 2022: 8 · 2021: 8 · 2020: 6 · 2019: 11 · 2018: 4 · 2017: 4 · 2016: 8 · 2015: 6 · 2014: 8 · 2013: 14 · 2012: 10
FWCI
4.41
Type
journal article
Language
en
Open access
closed
Locations
  • Journal of Applied Physiology (publishedVersion)
  • PubMed (publishedVersion)
  • Victoria University Research Repository (Victoria University) (submittedVersion)
  • UWA Profiles and Research Repository (UWA) (submittedVersion)
Topics
  • Health Sciences › Medicine › Orthopedics and Sports Medicine › Sports Performance and Training
  • Health Sciences › Medicine › Physiology (medical) › Cardiovascular and exercise physiology
  • Health Sciences › Nursing › Nutrition and Dietetics › Muscle metabolism and nutrition
Keywords
sodium bicarbonate ingestion, interval training, metabolic acidosis, lactate threshold, peak oxygen uptake, time to exhaustion, endurance performance, muscle metabolites, intracellular pH, exercise intensity, women
MeSH terms
Adaptation, Physiological, Administration, Oral, Adult, Humans, Hydrogen-Ion Concentration, Male, Oxygen, Oxygen Consumption, Physical Endurance, Physical Fitness, Task Performance and Analysis, Time Factors, Anaerobic Threshold, Exercise, Sodium Bicarbonate, Muscle, Skeletal

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