Physiological Aging: Links Among Adipose Tissue Dysfunction, Diabetes, and Frailty

Cited by (272)

Items 201–272 of 272

1. Impact of visceral adipose tissue on longevity and metabolic health: a comparative study of gene expression in perirenal and epididymal fat of Ames dwarf mice
   Agnieszka Zaczek, Andrzej Lewiñski, Małgorzata Karbownik‐Lewińska, Andrea Lehoczki, Adam Gesing · 2024 · GeroScience
2. Hypothalamic gene transfer of BDNF promotes healthy aging
   Lei Cao, Seemaab Ali, Nicholas J. Queen · 2021 · Vitamins and hormones
3. Adipose tissue aging partially accounts for fat alterations in HIV lipodystrophy
   Peré Domingo, Marta Giralt, Aleix Gavaldà‐Navarro, Albert Blasco‐Roset, Alejandro Delgado‐Anglés, José Miguel Gallego-Escuredo, María del Mar Gutiérrez, Gracia María Mateo, Rubén Cereijo, Joan Carles Domingo et al. · 2022 · Adipocyte
4. Age-related obesity and inflammaging in cats
   Miki Kobayashi, Motoo Kobayashi · 2025 · Frontiers in Veterinary Science
5. Association of Mitochondrial DNA Levels in Peripheral Blood Leukocytes With Physical Performance in Older Adults
   Hiroaki Ikezaki, Ryoko Nakashima, Hideyuki Nomura, Nobuyuki Shimono · 2026 · Geriatrics and gerontology international/Geriatrics & gerontology international
6. Bone, muscle, and sarcopenia
   Kristen M. Beavers, Monica C. Serra, Ashley A. Weaver, Denise K. Houston · 2020 · Elsevier eBooks
7. Differential and sex‐ and age‐specific risks of cardiometabolic diseases with unrelated metabolic syndrome dimensions
   Linjun Ao, Ko Willems van Dijk, Diana van Heemst, Raymond Noordam · 2023 · Obesity
8. Adipose Tissue Plasticity in Aging
   Guan Wang, Anying Song, Marie Bae, Qiong A Wang · 2022 · Comprehensive physiology
9. Phosphatidylcholine and frailty: a Mendelian randomization study and immune mediation
   Qunhua Han, Suisui Luo, Shunmei Huang, Yunmei Yang, Qin Zhang, Lijun Zhu · 2025 · Archives of Gerontology and Geriatrics
10. Multilevel Risk Factors Associated with Obesity in Older Latinos Ages 65 Years and Over
    Noé C. Crespo, Alma I. Behar, Janeth Juarez, John P. Elder · 2018 · Current Geriatrics Reports
11. Association Between Physical Status and the Effects of Combination Therapy With Renin-Angiotensin System Inhibitors and β-Blockers in Patients With Acute Heart Failure
    Kensuke Takabayashi, Shouji Kitaguchi, Takashi Yamamoto, Ryoko Fujita, Kotoe Takenaka, Hiroyuki Takenaka, Miyuki Okuda, Osamu Nakajima, Hitoshi Koito, Yuka Terasaki et al. · 2021 · Circulation Reports
12. A Pilot Study of Associations Between Visceral Fat, IL-6, and Urinary F2-Isoprostanes in Older Adults Exposed to a Diet Intervention
    Sarah E Hoover, Dora Il’yasova, Kevin R. Fontaine, Ivan Spasojević, Barbara Ann Gower, Amy Miskimon Goss · 2021 · Current Developments in Nutrition
13. The Complexity of Adipose Tissue
    Katie M. Troike, Kevin Y. Lee, Edward Owen List, Darlene E. Berryman · 2018 · Springer eBooks
14. Fatores associados à síndrome de fragilidade em idosos: análise de modelagem de equações estruturais
    Isabela Celano Corrochel, Nayara Gomes Nunes Oliveira, Gianna Fiori Marchiori, Sara Franco Diniz Heitor, Flávia Aparecida Dias, Darlene Mara dos Santos Tavares · 2021 · Acta Fisiátrica
15. Influence of obesity on biological age in patients with arterial hypertension
    Olena Vadymivna Kolesnikova, Olga Zaprovalna, T. М. Bondar, Anna Potapenko · 2023 · Arterial Hypertension
16. Obesity and Aging. General Aspects
    Yu. A. Dyleva, Ekaterina Vladimirovna Belik, Olga Victorovna Gruzdeva · 2023 · Российский физиологический журнал им  И  М  Сеченова
17. Patient characteristics of insulin lispro 200 units/mL users in real world setting in Germany
    Nanette Cathrin Schloot, Magaly Perez‐Nieves, Hélène Sapin, Silvia Kruppert, Thorsten Otto, Sheila M. Corrigan, Carolina Piras de Oliveira · 2020 · Current Medical Research and Opinion
18. A likelihood-based deconvolution of bulk gene expression data using single-cell references
    Dan D. Erdmann-Pham, Jonathan D. Fischer, Justin Hong, Yun S. Song · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
19. Obesity, inflammation, and aging
    Jacqueline J. Chu, Raman Mehrzad · 2022 · Elsevier eBooks
20. Obesity and Aging: General Aspects
    Yu. A. Dyleva, Ekaterina Vladimirovna Belik, Olga Victorovna Gruzdeva · 2023 · Journal of Evolutionary Biochemistry and Physiology
21. The role of body composition in the development of diabetes mellitus among childhood cancer survivors, and novel intervention strategies to mitigate diabetes risk
    Rusha Bhandari, Yue Liao, Ke Ma · 2025 · Cancer
22. Aging increases susceptibility to high-fat diet-induced neurobehavioral and mitochondrial dysfunction in zebrafish
    Victor Luna Picolo, Letícia A. Tavares, Whitney R. Santos, Nathasha P. Lopes, Ethiane R. dos Santos, Wembley Rodrigues Vilela, Angélica Amorim Amato, Paula Maria Quaglio Bellozi, Jair Trapé Goulart, César Koppe Grisólia et al. · 2025 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
23. Obesity accelerates aging: Mechanisms and therapeutic implications
    Ruiyan Zhang, Linlin Liu, Xiaoman Shi, Yanming Ren · 2025 · Genes & Diseases
24. A long-term human adipocyte organoid model reveals aging-associated responses to intermittent hypoxia
    Yunzhou Dong, Jingjing Wang, Feifei Feng, Isra H. Ali, Lida Chen, Shahid Karim, Joshua M. Bock, Virend Kristen Somers · 2026 · American Journal of Physiology-Cell Physiology
25. Cellular senescence and aging: molecular mechanisms and convergent pathways
    Francesca Cristiana Piritore, Michele Braggio, Arianna Minoia, Silvia Bolognin, Mattia Cominacini, Elisabetta Trabetti, Cristina Bombieri, Maria Grazia Romanelli, Luca Dalle Carbonare, Maria Teresa Valenti · 2026 · Cellular and Molecular Life Sciences
26. Long-Term Prognosis for Patients with Metabolic Syndrome after Recanalization Therapy for Stroke
    Ivana Kern, Svjetlana Šupe, Josip Ljevak, Katarina Starčević, Zdravka Poljaković · 2020 · Metabolic Syndrome and Related Disorders
27. The effect of eight weeks of high-intensity interval training vs. continuous training on serum Irisin levels and expression of skeletal muscle PGC-1α gene in male rats with metabolic syndrome
    Zohreh Borhani Kakhki, Sheila Naibifar, Hossein Nakhaei, Elham Ghasemi · 2022 · Journal of Sport and Exercise Physiology
28. Prevalence of Metabolic Syndrome and its associated risk factors among Passo do Lontra community at the Brazilian Pantanal
    Renato Ferreira de Almeida Zanre, Karine Mattos, Eliana da Costa Alvarenga de Brito, Vinícius de Alencar Ovelar, Ana Paula de Assis Sales, Eduardo Benedetti Parisotto, Albert Schiaveto de Souza, Wander Fernando de Oliveira Filiú, Simone Schneider Weber · 2022 · Research Society and Development
29. Understanding frailty and pre-frailty to improve chronic wound management in older people: a study protocol
    Duygu Sezgin, Aaron Liew, Georgina Gethin · 2023 · Journal of Wound Management Official journal of the European Wound Management Association
30. Clinical Significance of Changes in Serum Biochemical Indices, Blood Routine and Coagulation Function in Patients with Inflammatory Bowel Disease
    阳丽 徐 · 2024 · Advances in Clinical Medicine
31. Frequency and Sex-Specific Associations of Metabolic Syndrome in Rwandans Seeking Outpatient Care: A Cross Sectional, Single Centre Study
    James Gafirita, Cuthbert Musarurwa, Evariste Ntaganda, Marguerite Uwimana, Aime Dieudonne Hirwa, Mediatrice Mukahigiro, Laetitia Twizelimana, Marie Louise Nshimirimana, Stephen Rulisa, Charlotte Munganyinka Bavuma et al. · 2024 · Diabetes Metabolic Syndrome and Obesity
32. A modern approach to glucose-lowering therapy in frail older people with type 2 diabetes mellitus
    Ahmed H. Abdelhafiz, Daniel Pennells, Alan J. Sinclair · 2022 · Expert Review of Endocrinology & Metabolism
33. The metabolic benefits of thermogenic stimulation are preserved in aging
    Duraipandy Natarajan, Bhuvana Plakkot, Kritika Tiwari, Shoba Ekambaram, Weidong Wang, Michael Rudolph, Mahmoud Ali Mohammad, Shaji K. Chacko, Madhan Subramanian, Stefano Tarantini et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
34. Chronic β3 adrenergic agonist treatment improves brain microvascular endothelial function and cognition in aged mice
    Natarajan Duraipandy, Shoba Ekambaram, Stefano Tarantini, Raghavendra Yelahanka Nagaraja, Andriy Yabluchanskiy, Andria F. Hedrick, Vibhudutta Awasthi, Madhan Subramanian, Anna Csiszár, Priya Balasubramanian · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
35. "Exposure to Secondhand Smoke Exacerbated Natural Aging Cardiac Hypertrophy"
    Jia Ping Wu · 2020 · Open Journal of Cardiology & Heart Diseases
36. "New Approach to the Treatment of CoV-2 Infection by Means of Immune-modulators and Non-Steroid Anti- Inflammatory Drugs"
    Marta Navarro-Zorraquino · 2021 · Biomedical Journal of Scientific & Technical Research
37. Adipose Tissue Dysfunction
    William V. Trim, Dylan Thompson, James Edward Turner · 2020 · Springer eBooks
38. Testosterone and cardiovascular disease - a literature review
    Savi R Shishkov, Mila Boyadzhieva · 2022 · Scripta Scientifica Medica
39. Fgf6 Promotes Adipocyte Progenitor Cell Proliferation for Adipose Tissue Homeostasis
    Caizhi Liu, Meiyao Meng, Bo Xu, Guoqiang Li, Yuxiang Cao, Dongmei Wang, Jin Qiu, Jian Yu, Lingyan Xu, Xinran Ma et al. · 2022 · SSRN Electronic Journal
40. Faculty Opinions recommendation of Chronic inflammation in the etiology of disease across the life span.
    David Christopher Nieman · 2020 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
41. Osteoporose bei/durch Adipositas – Schutz oder Risiko?
    Hans‐Christof Schober, Katharina Kasch, Guido Schröder · 2022 · Osteologie/Osteology
42. Age-related changes in adipose tissue metabolomics and inflammation, cardiolipin metabolism, and ferroptosis markers in an aged rat model
    Zhuang‐Zhi Wang, Fanghui Li, Pin‐Shi Ni, Lei Sun, Chen‐Kai Zhang, Bo‐Ming Li, Jia‐Han He, Xiao‐Ming Yu · 2022 · Research Square
43. The impact of metabolic disorders on ageing rates in patients with moderate cardiovascular risk
    Olga Zaprovalna, Olena Vadymivna Kolesnikova, A. V. Potapenko, К.В. Вовк · 2022 · Науковий вісник Ужгородського університету Серія Медицина
44. Chapter 2. Physiological and Clinical Considerations of Geriatric Patient Care
    Jaclyn Jaeger, George A. Kuchel · 2022 · American Psychiatric Association Publishing eBooks
45. Prevalence and Related Factors of Lower Urinary Tract Infection in Frail Older Adults Undergoing Major Noncardiac Surgery
    Warin Thangrom, Inthira Roopsawang, Suparb Aree‐Ue · 2023 · Geriatrics
46. DIFFERENTIAL NUMBER OF LEUCOCYTES IN PATIENTS WITH TYPE 2 DIABETES MELLITUS TREATED WITH DIABETIC VASCULAR FOOT EXERCISE
    Sunita Sunita, Muhammad Rizky Akbar, Mohammad Ghozali, Mas Rizky A. A. Syamsunarno · 2022 · Proceeding B-ICON
47. The Impact of Behavioral Lifestyle Intervention on Inflammatory Cytokines in Older Adults Living With Type 2 Diabetes: A Feasibility Study
    Rozmin B. Jiwani, Monica C. Serra, Sara E Espinoza, Andrea Berndt, Darpan I. Patel · 2024 · INQUIRY The Journal of Health Care Organization Provision and Financing
48. Weißes Fettgewebe
    Thomas Skurk, Matthias Blüher, Stefan Engeli · 2024 · Springer eBooks
49. Comparação entre cinco índices de adesão ao padrão da dieta mediterrânea e sua associação com inflamação sistêmica e transtornos mentais comuns em adultos e idosos residentes no município de São Paulo em 2015
    Amália Almeida Bastos · 2024 · Digital Library of Theses and Dissertations (Universidade de São Paulo)
50. Significance of Adipose Tissue as an Endocrine Organ
    Dimiter Bogdanov Avtanski, Radoslav Stojchevski · 2024 · Contemporary Endocrinology
51. Chronic β3 adrenergic agonist treatment improves neurovascular coupling responses, attenuates blood-brain barrier leakage and neuroinflammation, and enhances cognition in aged mice
    Natarajan Duraipandy, Shoba Ekambaram, Stefano Tarantini, Raghavendra Yelahanka Nagaraja, Andriy Yabluchanskiy, Andria F. Hedrick, Vibhudutta Awasthi, Madhan Subramanian, Anna Csiszár, Priya Balasubramanian · 2025 · Aging
52. Decreased protein activator of interferon induced protein kinase (PRKRA) involved in menopause-related cholesterol metabolic disorders by regulating cholesterol biosynthesis
    Le Xu, Jian Xu, Wanting Shi, Sa Zhang, Ting Guo, Shien Zou · 2025 · Lipids in Health and Disease
53. C-C chemokine ligand 5 from women subcutaneous adipose tissue has a central role in vascular aging
    Laura Pelletier, Kenza Ngono Ayissi, Jennifer Gorwood, Émilie Capel, Romain Morichon, Matthieu Mantecon, Martine Auclair, Rohia Alili, Christine Katlama, Lise Cuzin et al. · 2025 · Cardiovascular Diabetology
54. Research Progress on Frailty and Cardiovascular Risk Factors in Middle-Aged and Elderly People
    佳萌 石 · 2025 · Advances in Clinical Medicine
55. Additional file 1 of Prevalence of metabolic syndrome in primary health settings in Qatar: a cross sectional study
    Syed, Mohamed Ahmed, Al Nuaimi, Ahmed Sameer, Latif Zainel, Abdul Jaleel A., Hamda Abdulla A Qotba · 2020 · Figshare
56. Associations Between Klotho/FGF-Related Protein Expression in Peripheral Blood Mononuclear Cells, Inflammation, and Muscle Function in Middle-Aged Adults with Obesity: A Pilot Study
    Diana Ariadel Cobo, Brisamar Estébanez, Elena González Arnáiz, María Pilar García-Pérez, Marta Rivera-Viloria, Alejandra Villasante Santos, Begoña Pintor de la Maza, David E. Barajas Galindo, Diana García Sastre, Maria Jose Cuevas et al. · 2026 · International Journal of Molecular Sciences
57. The “fat heat-up” phenotype: adipose tissue hypermetabolism on 18 F-FDG PET/CT predicts frailty in older patients with solid tumours
    Gürsan Kaya, Serdar Ceylan, Meltem Gulhan Halil, Ömer Uğur · 2026 · European Journal of Nuclear Medicine and Molecular Imaging
58. Body Composition Characteristics in Aging Populations: Clinical Limitations of BMI and Implications for Chronic Metabolic Diseases
    Yiting Zhao, Jiangbo Ye, Wansu Yu, Qian Du, Donghui Liu · 2026 · IntechOpen eBooks
59. Multi-organ non-invasive tissue characterization of fibrosis, adipose tissue, edema and inflammation with magnetic resonance (MR) imaging : applications to myocardium, skeletal muscle and liver interactions
    Adrian Thomas Huber · 2019
60. Regulation of lipogenesis in human adipose tissue : effect of metabolic stress, dietary intervention and aging
    Veronika Šrámková · 2017
61. Epidémiologie de la fragilité entre 45 et 75 ans : prévalence et facteurs associés dans deux cohortes françaises
    Benjamin Landré · 2020
62. Caractérisation structurale et fonctionnelle du tissu adipeux périprostatique : implication dans le cancer de la prostate
    Mathieu Roumiguié · 2022
63. Semaglutide Treatment in Young Adults Living With Type 2 Diabetes: A Post Hoc Analysis From the SUSTAIN and PIONEER Clinical Trials
    Francesco Zaccardi, Vanita R. Aroda, Ecenur Guder Arslan, Lars Bardtrum, Jonathan Goldney, Erik Ising, Prachi Priyadarshini, Tommy Slater, Melanie Jane Davies · 2026 · Diabetes Obesity and Metabolism
64. Senescent cells induce vascular MHC II to recruit CD4 + T cells and drive inflammation in aging adipose tissue
    Qijing Xie, Tzu‐Hua Lin, SoRi Jang, Calvin H. Jan, Amirali Selahi, Kendra Dee Nyberg, Agnieszka A. Wendorff, Kayley Hake, Austin E. Y. T. Lefebvre, Meng Jin et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
65. The Ageing Adipose Paradox: Implications for Metabolic Health
    Dana Bou Matar, Muhammad Affan Elahi, Walid Khaled Nassar, Mohammed I. Alotaibi, David Murphy, Hana M. A. Fakhoury, Ahmad Aljada · 2026 · Diabetes Obesity and Metabolism
66. Role of Obesity-Triggered Inflammation in Aging
    Tamàs Fülöp, Maximilien Franck, Alan Arthur Cohen, Mehdi Alami, Hicham Berrougui, Abdelouahed Khalil, Graham Pawelec, Jacek Maciej Witkowski · 2026 · Healthy ageing and longevity
67. Rethinking frailty as a disorder of mitochondrial adaptability, from energetic congestion to systemic vulnerability
    Rebecca DE LORENZO, Patrizia Querini Rovere · 2026 · Pharmacological Research
68. Blood Flow Restriction in Older Adults: Implications and Interventions for Sarcopenia Management
    Ben Friedman, Julie Rekant, Kathleen R. Dondero, Brock A. Beamer, Steven J. Prior, Odessa R. Addison · 2026 · Topics in Geriatric Rehabilitation
69. Insulin resistance, aging biology, and non- communicable chronic diseases: a narrative review of bidirectional mechanisms and translational implications
    Sidhartha Gautam Senapati · 2026 · Frontiers in Endocrinology
70. Exploratory associations between CT-derived body composition and MRI-based infrapatellar fat pad profiles with age-stratified analyses: a retrospective cross-sectional study
    Seunghyun Song, Hee Sang Oh, Sung Jun Kim, Hong Seon Lee · 2026 · BMC Musculoskeletal Disorders
71. Human β‐Cell Dedifferentiation and Diabetes
    Jiajun Sun, Jinsook Son, Qidi Wang · 2026 · Journal of Diabetes
72. Dissecting the shared genetic architecture of adipose tissue aging and aging-related lipid-metabolic dysfunction: a multivariate genomic analysis
    Li, Mingkai, Yao, Yunshu, Zhao, Yafei, Guo, Qinfei, Li, Chenyang, Lv, Chenhui, Zhang, Boqian, Li, Jinxin, Zhao, Haifeng · 2026 · Biogerontology