Modeling physiological events in 2D vs. 3D cell culture

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Items 1,601–1,700 of 1,846

1. Development of a Single-Neurosphere Culture to Assess Radiation Toxicity and Pre-Clinical Cancer Combination Therapy Safety
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3. LIVECell—A large-scale dataset for label-free live cell segmentation
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4. The comparison of gold nanoparticles effectiveness in 2D and 3D cell culture.
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5. Comparative functional aspects of 3T3 fibroblasts in 2D and 3D cell- culture environment
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6. Are the BPA Analogues a Plausible Alternative to BPA? Alternative 3D in Vitro Neuron Model is Compared with the Classical 2D Model to Assess Cytotoxic and Genotoxic Effects
   Marta Sendra, Mónica Cavia-Sáiz, Pilar Múñiz · 2023 · SSRN Electronic Journal
7. In Vitro Comparison of Three-Dimensional Cultured Periodontal Ligament Stem Cells Derived from Permanent and Supernumerary Teeth
   Hee‐Jin Kim, Ko Eun Lee, Yong Kwon Chae · 2023 · Applied Sciences
8. Dispositivo microfluídico reversível e reutilizável para o estudo do comportamento celular em diferentes concentrações de fármacos
   Franciele Flores Vit · 2021
9. Experimental models of biliatresone-induced biliary atresia
   Gehenna Lobo Guerrero Serrano · 2023
10. Laser-printed 3D full-thickness skin equivalent morphology and metabolism monitoring by dual-mode OCT/Fluorescence system
    Sergei G. Sokolovski, Arooj Khalid, Дрёмин Виктор Владимирович, Ayman El-Tamer, Maria Surmina, Celine Lancelot, Рафаилов Эдик Урихаевич · 2023 · Research Square
11. Perspective Chapter: Evaluating New Drugs against K-Ras4B/PDE6δ Using an In Vitro Approach
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12. [Characterization of a 3-dimensional tuberculosis spheroid model constructed using human monocytic THP-1 cells and Bacillus Calmette-Guerin].
    J Guo, Yang Qiu, C Hu, D Li, Yan Du · 2023 · PubMed Central
13. Role of silk fibroin biomaterials as artificial ECM for 3D in vitro modeling
    Viviana P. Ribeiro, Rui Luís Reis, Joaquim Miguel Oliveira · 2024 · Elsevier eBooks
14. Development of an in vitro mouse cultured uterine tissue model for the endometrial regenerative therapy
    Le Thi Vi Tuyet, Tuyet Thi Diem Hoang, Ha Le Bao Tran · 2023 · Science and Technology Development Journal - Natural Sciences
15. Strategies to investigate migration and metastases in thyroid cancer
    Daniel M. Chopyk, Priya H. Dedhia · 2024 · Current Opinion in Endocrine and Metabolic Research
16. Thermo-responsive poly(di(ethylene glycol) methyl ether methacrylate) brushes as substrate-independent release coatings for cell culture and selective cell separation and purification
    Anna K. Schulte, Daniel Wesner, Mareike Müller · 2024 · Pure and Applied Chemistry
17. A multi-model study of extracellular vesicles in bowel cancer invasion and metastasis
    Sonia Guarnerio · 2023 · Sheffield Hallam University
18. 3D cell culture of nanofiber hydrogel promotes the growth and osteogenesis of bone marrow mesenchymal stem cells (BMSC)
    Chunyu Jiang, Feng Sun · 2024 · Materials Express
19. Cell-based in vitro models for dermal permeability studies
    Ana Margarida Silva, Maria João Bessa, Francisca Rodrigues · 2024 · Elsevier eBooks
20. Mechanoregulation of angiopoietin-like 4 in epithelial-mesenchymal transition and cancer metastasis
    Zehuan Liao · 2023
21. JoVE Video Dataset
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22. Skin wound healing using topical treatment with própolis
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23. Methodology and Tools for Metallomics
    Xiaowen Yan, Ming Xu, Qiuquan Wang · 2024
24. Engineering the bone marrow microenvironment
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25. Photonics technologies in constituting human 3D tissue models
    Sergei G. Sokolovski, Рафаилов Эдик Урихаевич · 2024
26. Organ-on-a-chip for multianalyte monitoring
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27. Aggressive KRAS mutations direct TGF-β response towards partial EMT in patient-derived colorectal cancer tumoroids
    Theresia Mair, Philip König, Milena Mijović, Loan Tran, Pedro Morata Saldaña, Carlos Uziel Pérez Malla, Kristina Draganić, Janette Pfneissl, Andreas Tiefenbacher, Julijan Kabiljo et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
28. Caracterização de células endometriais humanas em sistema 3D: o modelo e suas possibilidades de estudo
    Bárbara S.S. Souza · 2024
29. Comparative Morphological and Molecular Genetic Characteristics of Cell and Tissue Strains of Experimental Rat Glioma 10-17-2 (Astrid-17)
    А. И. Алексеева, Vera Vladimirovna Kudelkina, Alexander S. Khalansky · 2024 · Bulletin of Experimental Biology and Medicine
30. Detecting Nanotopography Induced Changes in Cell Migration Directions Using Oxygen Sensors
    Muting Wang, S. W. Pang · 2024 · Biosensors
31. Biocompatibility of Microsystems
    Siyuan Li, Shane Scott, Linan Cui, Ayse Z. Turak, Kyla N. Sask · 2024 · Elsevier eBooks
32. In Vitro Assays Used to Analyse Vascular Cell Functions
    Adrian Kirchhoff, Christian Wechselberger, David Bernhard, Barbara Meßner · 2024 · Learning materials in biosciences
33. Transforming heart disease research with cardiac organoid technologies
    Durgapada Sarkhel · 2024
34. Endogenous gene tagging with FnCas9 to track and sort neural lineages from 3D cortical organoids
    Manoj Kumar, Berta Terré, François Guillemot, Debojyoti Chakraborty · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
35. Time-dependent chromatin maturation during 3D spheroid culture improves preclinical modeling of non-small cell lung cancer
    Anaïs Darracq, Nicolas Sgarioto, Marielle Huot, Gabrielle McInnes, Antoine Méant, Alexandra Langford‐Avelar, Oscar David Villarreal, François Marois, Maxime Caron, Pascal St-Onge et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
36. Macrophage-Mediated Control of Implant-Associated Biofilms in a Three-Dimensional Human Oral Mucosa Model
    Muhammad Imran Rahim, Shuli Chen, Carina Mikolai et al. · 2025 · SSRN Electronic Journal
37. Phenotypic similarity of spheroids of native chondrocytes and spheroids of chondrocytes differentiated from human induced pluripotent stem cells using recombinant factors TGF-β1 and BMP2
    Evgenii S. Ruchko, Polina A. Golubinskaya, Arina S. Pikina · 2025 · Genes and Cells
38. Three-dimensional tissue platform co-laid with native collagen fibers and cells for phenotypic screening of stem cell interactions
    Rui Tang, Aixiang Ding, Chen Sheng Fu et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
39. Comparison of the apoptotic and cytotoxic effects of Astragalus hamosus in the two- and three-dimensional cultures of human umbilical vein endothelial cells
    Mozaffar Mahmoodi, Golara Nasiri · 2024 · Scientific Journal of Kurdistan University of Medical Sciences
40. An Automatic Diverter Microfluidic Chip with Dual-Channel Concentration Gradient for Drug Screening of Head and Neck Tumor Cells
    Zhimi Zhang, Jingru Liao, Xu Ru · 2025 · Proceedings, IEEE micro electro mechanical systems
41. In vitro study on the comparison of hypoxia-inducible factor-1α expression after particulate matter exposure in 2-dimensional and 3-dimensional cell culture models
    Ji-O Ryu, Eunyoung Lee, Sang‐Yun Lee, Hyeong Jun Cho, Jeong Uk Lim, Chang Dong Yeo, Yu-Jeong Seong, Seung Joon Kim, Dong Woo Lee · 2025 · Organoid
42. Lung cancer: Current status of preclinical research
    Emmanuel Boadi Amoafo, Elizabeth Twum, Bismarck Afedo Hottor, Mansa Fredua‐Agyeman, Awo Afi Kwapong, Seth Kwabena Amponsah · 2025 · Elsevier eBooks
43. Method for Culturing and Imaging Homogeneous 3D Cancer Spheroids as a Model for the Uptake of DNA Nanostructures
    Emanuela Mensa’, Giampaolo Zuccheri · 2025 · Methods in molecular biology
44. Suppression of cancer cell growth using nanoparticles containing two different amino acid-degrading enzymes
    Shuhei Murayama, Hiromu Kurase, Kanako Tatsubori · 2025 · Journal of Nanoparticle Research
45. Cultivo de células animales murinas y humanas: una perspectiva histórica
    José Luis Ventura-Gallegos, Eric Alejandro García López, José Alberto Cabrera Quintero · 2025 · TIP Revista Especializada en Ciencias Químico-Biológicas
46. Metabolome Extraction from 2D and 3D Colorectal Cancer Cell Cultures
    Paula A. Buriticá-Macías, Jorge Alejandro Lopera-Rodríguez, Sarah Röthlisberger · 2025 · World Congress on Medical Physics and Biomedical Engineering, September 7 - 12, 2009, Munich, Germany
47. Personalized Gut–Liver Microphysiological System Maps Donor-Specific Tissue-Resident Immunity and Reveals a Conserved Metabolic Crosstalk
    Merve Uslu, Ran Ran, Mohd Farhan Siddiqui, Jing Liang, Luther Raechal, Matjaz Dogsa, Carole Y. Perrot, Linda A. Lieberman, Douglas K. Brubaker, Martin Trapečar · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
48. Bridging the gap: Canine in vitro models of the central nervous system as tools to study pathogenetic mechanisms in neurodegenerative disease and neuroinfectiology
    Georg Beythien, Svenja Becker, Eva Leitzen, Sayali Kalidas Kohale, Wolfgang Baumgärtner · 2025 · Veterinary Pathology
49. Testicular Cell–Conditioned Chitosan Thermosensitive Hydrogel as an Excellent Substrate for Culture and Proliferation of Spermatogonia Cells
    Monireh Mahmoodi, Mahdieh Gholipour-Malekabadi · 2025 · BioMed Research International
50. 3D Tissue Culture Model for Virology Studies
    Dandan Li, Chunfu Zheng · 2025 · Methods in molecular biology
51. İki-boyutlu ve Üç-boyutlu Hücre Kültür Modellerinde Güncel Gelişmeler ve Uygulamalar
    Güneş Kibar, Atakan Tevlek · 2025 · Arşiv Kaynak Tarama Dergisi
52. Comparison of 2D and 3D culture methods on morphology, viability, surface markers, and pluripotency gene of umbilical cord mesenchymal stem cells
    Wahyunia Likhayati Septiana, Raudina Azzahra, Abdullah Ahmad, Dharma Nurvianto, M. Faishal Budi Utomo, Helsy Junaidi, Sastia Winda Astuti · 2025 · Journal of Cellular Biotechnology
53. 3D co-cultures of primary human hepatocytes and Kupffer-like cells to address innate immune responses to rAAV
    Isabella Ramella Gal, Francisca Arez, Inês P. Correia et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
54. Improving Human Pluripotent Stem Cells Maintenance with Advanced Engineered 3D Culture Platform
    Tuğba Topal · 2025 · Springer tracts in additive manufacturing
55. Hydrogel-patterning technique for 3D cell culture
    Uzma Farooq, Sradhanjali Mohapatra, Ahsan Ali · 2025 · Elsevier eBooks
56. Biphasic Mechanical Loading Disrupts Cytoskeletal Symmetry in 3D Architected Scaffolds
    Kailin Chen, Alexander Bolanos-Campos, Mistica Lozano Perez, Erin Berlew, Tianbai Wang, Luc Capaldi, Ran N. Tao, Arnold J. T. M. Mathijssen, Joel D. Boerckel, Ottman A. Tertuliano · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
57. Cellular Crosstalk Between Periodontal Ligament Fibroblasts and Macrophages: Insights from 2D and 3D Culture Systems in External Inflammatory Root Resorption
    Rajeshwari Hadagalu Revana Siddappa, Anil Kishen · 2025 · Journal of Endodontics
58. Nanosafety: Why Do We Need It?
    Ernesto Alfaro‐Moreno, Fiona A Murphy · 2025 · Springer eBooks
59. Impact of 2D versus 3D fibroblast models on Leishmania species invasion in vitro: Rab5 dynamics and actin activity in initial infection
    Rebecca Thereza Silva Santa Brígida, Adeniele Lopes da Cruz Carneiro, Felipe Tuji de Castro Franco, Brenda Furtado Costa, Ana Paula Drummond Rodrigues · 2025 · Frontiers in Cellular and Infection Microbiology
60. Human Rhinovirus 16 impacts cilia structure in 3D cultured primary bronchial epithelial tissue through alternative splicing of host cilia RNAs
    Christoforos Rozario, Quan Gu, Andrew Stevenson · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
61. Exploring the biomechanical complexity of glioblastoma spheroids and organoids with co-localized Brillouin and Raman microspectroscopy
    Roberta Galli, Jan Rix, Tina Leonidou · 2025 · Biochemistry and Biophysics Reports
62. Modeling human kidney in vitro - the potential of renal organoids and tubuloids for urology
    Viktória Filipková, Tomáš Pelikán, Roman Zachoval, Petr Heneberg · 2025 · Česká urologie
63. New Advances in 3D Models to Improve Diabetic Keratopathy Research: A Narrative Review
    Nicoletta Palmeri, Agata Grazia D’Amico, Carla Cavallaro, Giuseppe Evola, Velia D’Agata, Grazia Maugeri · 2025 · Applied Sciences
64. Fabrication of a Three-Dimensional Chondrocyte Sheet with a Collagen Layer-by-Layer Nanofilm Coating Technique to Mimic Cartilage
    Yih-Wen Tarng, Chwen-Ru Lin, Szu‐Yin Ou · 2025 · ACS Applied Polymer Materials
65. Three-Dimensional Cartilage Tissue Engineering Using Placenta-Derived Extra-Embryonic Mesenchymal Stem Cells: From Isolation to Differentiation
    Cem Müjde, Atıl Bişgin · 2025 · Biomedicines
66. Development and characterization of gelatin-based scaffolds for 3D cancer cell culture
    Bahar Yılmaz, Esra Armağan, Mukaddes Keskinateş, Ziya Aydın, Mevlüt Bayrakcı · 2025 · Journal of Scientific Reports-A
67. Mechanical interaction among cells in hydrogel-based microfluidic assays
    Lei Li, Jiaqi Zhang, Pengtao Yue, James J. Feng · 2025 · Biomicrofluidics
68. Release, Transfer, Fold: Using a Silicone Adhesive for On-Demand 3D Tissue Engineering
    Doris Roth, Benedetta Zampa, Romina Augustin, Daara Payandehjoo, Giancarlo Porcella, Ayşe Tuğçe Şahin, Anne M. van der Does, Janna C. Nawroth · 2025 · ACS Biomaterials Science & Engineering
69. Modelling catheter-associated bladder mucosal adhesion and microtrauma using a human urothelial microtissue model
    Nazila V. Jafari, Jennifer L. Rohn · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
70. Computational modeling of hormone- and cytokine-dependent proliferation of endometrial cells in 3D co-culture
    Wangui Mbuguiro, Samantha E. Holt, Linda Gay Griffith, Juan S. Gnecco, Feilim Mac Gabhann · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
71. A quantitative framework for interpreting rate and capacity effects in oral regenerative scaffolds
    Maria Teresa Colangelo, Stefano Guizzardi, Carlo Galli · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
72. Biomimetic Models for Investigation of Microvascular Remodeling
    Nien‐Wen Hu, Arinola O. Lampejo, Ariana Diandra Suarez‐Martinez, Nicholas A. Hodges, Mir Md Nasim Hossain, Péter Balogh, Bing Ren, Yong Hong Huang, Jonathan J. Adorno, Shashwat Agarwal et al. · 2025 · Physiology in health and disease
73. In vitro approaches to study centriole and cilium function in early mouse embryogenesis
    Isabella Voelkl, Tamara Civetta, Mirijam Egg · 2025 · Life Science Alliance
74. Directed Cell Self-Assembly to Form Tendon and Muscle Models for Studying Early Stages of Musculoskeletal Tissue Formation
    Tabitha R. Stephenson, Colin R. Marchus, Alonna Clair · 2025 · Journal of Biomechanical Engineering
75. Time-dependent epigenomic changes during 3D spheroid culture improve the preclinical modeling of non-small cell lung cancer
    Anaïs Darracq, Nicolas Sgarioto, Marielle Huot, Gabrielle McInnes, Antoine Méant, Alexandra Langford‐Avelar, Oscar David Villarreal, François Marois, Maxime Caron, Pascal St-Onge et al. · 2025 · Research Square
76. Capitalizing on mechanistic insights to power design of future-ready intracellular optogenetics tools
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77. Mechanism of LEPR-mediated cholesterol metabolism involved in NK cell function suppression under simulated microgravity
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78. Mevalonate pathway activation in Ewing sarcoma reveals a 3D-specific synergy between statins and BCL-xL inhibition
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79. Poroelastic mechanical loading disrupts cytoskeletal symmetry in 3D architected scaffolds
    Kailin Chen, Alexander Bolanos-Campos, Mistica Lozano Perez, Erin E. Berlew, Tianbai Wang, Luc N. Capaldi, Ran Tao, Arnold J. T. M. Mathijssen, Joel D. Boerckel, Ottman A. Tertuliano · 2025 · Biophysical Journal
80. OSCAR is an online ML-powered tool for organoid cell counting using bright-field images
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81. Geltrex‐Enhanced Two‐Dimensional Culture as a Viable Alternative to Primary Rat Hepatocyte Sandwich Models
    Eda Beldek, Matilda Holtz, Adi̇l Deni̇zli̇, Osman Berk Usta · 2025 · Comprehensive physiology
82. Cultured chicken meat developed by structuring cellular spheroids on an edible bacterial nanocellulose bioscaffold
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83. Additional file 1 of Marker-controlled watershed with deep edge emphasis and optimized H-minima transform for automatic segmentation of densely cultivated 3D cell nuclei
    Kaseva, Tuomas, Omidali, Bahareh, Hippeläinen, Eero · 2022 · Figshare
84. Additional file 1 of Tissue engineering RPE sheet derived from hiPSC-RPE cell spheroids supplemented with Y-27632 and RepSox
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85. Additional file 1 of Role of beta-(1→3)(1→6)-D-glucan derived from yeast on natural killer (NK) cells and breast cancer cell lines in 2D and 3D cultures
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86. Additional file 3 of Tissue engineering RPE sheet derived from hiPSC-RPE cell spheroids supplemented with Y-27632 and RepSox
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87. Additional file 1 of A microfluidic-based analysis of 3D macrophage migration after stimulation by Mycobacterium, Salmonella and Escherichia
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88. In vitro and in vivo assays
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89. Evaluation of the Photoprotective Effect of Titanium Oxide Nanotubes on Spheroids of hFOB 1.19 Cells
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90. Cellular uptake of anisotropic microparticles in 2D and 3D culture systems
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91. Selective estradiol sensitivity in 12Z human endometriotic epithelial cell line
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92. Exploring metabolic dynamics of cancer metastasis through in vitro models
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93. Biomimetic Molecular Tweezing at Biointerfaces: A Surface‐Driven Strategy to Disrupt Globular Protein Binding While Aligning ECM for Controlled Cellular Activity
    Althaf Umar K.P., Kaladhar Kamalasanan, Sreejith Thrivikraman Nair, Praveen Kerala Varma, Harika Sapa, Shona Sara Shaji, Sherin Ann Mathew, Ayana Kannaghut Puthukudi · 2026 · Biopolymers
94. Hypoxic conditions confer chemoresistance to crizotinib but not to imatinib in chronic myeloid leukemia cells
    Lena Avinery, Danielle Regev, Hazem Khamaisi, Jacob Gopas, Jamal A. Mahajna · 2026 · Hematology Transfusion and Cell Therapy
95. Cell Culture Substrate Variation Alters Extracellular Vesicle Biogenesis Without Affecting Non‐Coding Repeat RNA Profile
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96. Rapid Generation of Fusable Cell Beads for Multi‐Scale Human Living Materials Assembly
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97. Development and Characterization of Copaiba Oil‐Loaded Polymeric Nanocapsules With Enhanced Antitumor Activity Against Breast Cancer Cells
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98. Transition from two‐dimensional to three‐dimensional models of endothelial cell cultures
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99. Advanced In Vitro Models to Assess Contaminants Toxicity by Ingestion
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100. Reengineering 3D cellular-scale stiffness gradient at the enthesis with biomimetic hydrogels to promote in situ chondrogenesis
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