The DOI matches its Crossref record; 585 of the 585 references it cites were found in a registry or an index.
Physiology and Pathophysiology of the Calcium Store in the Endoplasmic Reticulum of Neurons
Abstract
The endoplasmic reticulum (ER) is the largest single intracellular organelle, which is present in all types of nerve cells. The ER is an interconnected, internally continuous system of tubules and cisterns, which extends from the nuclear envelope to axons and presynaptic terminals, as well as to dendrites and dendritic spines. Ca 2+release channels and Ca 2+pumps residing in the ER membrane provide for its excitability. Regulated ER Ca 2+release controls many neuronal functions, from plasmalemmal excitability to synaptic plasticity. Enzymatic cascades dependent on the Ca 2+concentration in the ER lumen integrate rapid Ca 2+signaling with long-lasting adaptive responses through modifications in protein synthesis and processing. Disruptions of ER Ca 2+homeostasis are critically involved in various forms of neuropathology.
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Cited by
Kettenmann, H., Hanisch, U.-K., Noda, M., & Verkhratsky, A. (2011) · Physiological Reviews · doi:10.1152/physrev.00011.2010 · Cited by 3,547
Self-citationVerkhratsky, A., & Nedergaard, M. (2018) · Physiological Reviews · doi:10.1152/physrev.00042.2016 · Cited by 1,678
Self-citationMicrodomains of Intracellular Ca2+: Molecular Determinants and Functional Consequences
Rizzuto, R., & Pozzan, T. (2006) · Physiological Reviews · doi:10.1152/physrev.00004.2005 · Cited by 1,206
Inositol Trisphosphate Receptor Ca2+Release Channels
Foskett, J. K., White, C., Cheung, K.-H., & Mak, D.-O. D. (2007) · Physiological Reviews · doi:10.1152/physrev.00035.2006 · Cited by 1,188
The Postsynaptic Architecture of Excitatory Synapses: A More Quantitative View
Sheng, M., & Hoogenraad, C. C. (2007) · Annual Review of Biochemistry · doi:10.1146/annurev.biochem.76.060805.160029 · Cited by 1,003
Metadata
- Authors
- Verkhratsky, A.
- Venue
- Physiological Reviews
- Publisher
- American Physiological Society
- Published
- 2005-01
- Volume
- 85
- Issue
- 1
- Pages
- 201-279
- ISSN
- 0031-9333 (ISSN-L)
- 1522-1210
- OpenAlex
- W2122054000
- Cited by
- 709
- References
- 585
- FWCI
- 2.17
- Type
- journal article
- Language
- en
- Open access
- closed
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