The DOI matches its Crossref record; 3 of the 3 references it cites were found in a registry or an index.
Controlling Cell Behavior Electrically: Current Views and Future Potential
Abstract
Direct-current (DC) electric fields are present in all developing and regenerating animal tissues, yet their existence and potential impact on tissue repair and development are largely ignored. This is primarily due to ignorance of the phenomenon by most researchers, some technically poor early studies of the effects of applied fields on cells, and widespread misunderstanding of the fundamental concepts that underlie bioelectricity. This review aims to resolve these issues by describing: 1) the historical context of bioelectricity, 2) the fundamental principles of physics and physiology responsible for DC electric fields within cells and tissues, 3) the cellular mechanisms for the effects of small electric fields on cell behavior, and 4) the clinical potential for electric field treatment of damaged tissues such as epithelia and the nervous system.
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Citations
Cites
Turning of nerve growth cones induced by neurotransmitters
Zheng, J. Q., Felder, M., Connor, J. A., & Poo, M.-M. (1994) · Nature · doi:10.1038/368140a0 · Cited by 580
A small, physiological electric field orients cell division
Zhao, M., Forrester, J. V., & McCaig, C. D. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.9.4942 · Cited by 186
Self-citationMenu, E., Kooijman, R., Valckenborgh, E. V., Asosingh, K., Bakkus, M., Camp, B. V., & Vanderkerken, K. (2004) · British Journal of Cancer · doi:10.1038/sj.bjc.6601613 · Cited by 115
Cited by
Neural tissue engineering options for peripheral nerve regeneration
Gu, X., Ding, F., & Williams, D. F. (2014) · Biomaterials · doi:10.1016/j.biomaterials.2014.04.064 · Cited by 630
Role of membrane potential in the regulation of cell proliferation and differentiation
Sundelacruz, S., Levin, M., & Kaplan, D. L. (2009) · Stem Cell Reviews and Reports · doi:10.1007/s12015-009-9080-2 · Cited by 489
Electromagnetic effects—From cell biology to medicine
Funk, R. H. W., Monsees, T., & Özkucur, N. (2009) · Progress in Histochemistry and Cytochemistry · doi:10.1016/j.proghi.2008.07.001 · Cited by 423
Giladi, M., Schneiderman, R. S., Voloshin, T., Porat, Y., Munster, M., Blat, R., Sherbo, S., Bomzon, Z., Urman, N., Itzhaki, A., et al. (2015) · Scientific Reports · doi:10.1038/srep18046 · Cited by 327
Pires, F., Ferreira, Q., Rodrigues, C. A. V., Morgado, J., & Ferreira, F. C. (2015) · Biochimica et Biophysica Acta (BBA) - General Subjects · doi:10.1016/j.bbagen.2015.01.020 · Cited by 276
Metadata
- Authors
- McCaig, C. D., Rajnicek, A. M., Song, B., & Zhao, M.
- Venue
- Physiological Reviews
- Publisher
- American Physiological Society
- Published
- 2005-07
- Volume
- 85
- Issue
- 3
- Pages
- 943-978
- ISSN
- 0031-9333 (ISSN-L)
- 1522-1210
- OpenAlex
- W2118661742
- Cited by
- 1,096
- References
- 3
- FWCI
- 1.44
- Type
- journal article
- Language
- en
- Open access
- closed
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- McCaig, C. D., Rajnicek, A. M., Song, B., & Zhao, M. (2005). Controlling Cell Behavior Electrically: Current Views and Future Potential. Physiological Reviews. https://doi.org/10.1152/physrev.00020.2004
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