Evolution and function of the ADP ribosyl cyclase/CD38 gene family in physiology and pathology

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Items 201–377 of 377

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15. CD38-deficient mice have reduced airway hyperresponsiveness following IL-13 challenge
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16. ADP-Ribosyl Cyclase in Rat Vascular Smooth Muscle Cells
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17. Role of NADase in Virulence in Experimental Invasive Group A Streptococcal Infection
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18. Anti-CD38-blocked ricin: an immunotoxin for the treatment of multiple myeloma [see comments]
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19. Activation of CD38 by Interleukin-8 Signaling Regulates Intracellular Ca2+ Level and Motility of Lymphokine-activated Killer Cells
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20. Relationship between the frequency of HIV-specific CD8 + T cells and the level of CD38 + CD8 + T cells in untreated HIV-infected individuals
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21. CD38 is the major enzyme responsible for synthesis of nicotinic acid–adenine dinucleotide phosphate in mammalian tissues
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22. CD38 ligation in human B cell progenitors triggers tyrosine phosphorylation of CD19 and association of CD19 with lyn and phosphatidylinositol 3-kinase
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23. CD38/CD31, a Receptor/Ligand System Ruling Adhesion and Signaling in Human Leukocytes
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25. Structural Basis for Formation and Hydrolysis of the Calcium Messenger Cyclic ADP-ribose by Human CD38
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26. Interaction of Two Classes of ADP-ribose Transfer Reactions in Immune Signaling
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27. Expression of cyclic ADP-ribose-synthetizing CD38 molecule on human platelet membrane
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29. Human Anti-CD38 Autoantibodies Raise Intracellular Calcium and Stimulate Insulin Release in Human Pancreatic Islets
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30. CD38 Signaling in B Lymphocytes Is Controlled by Its Ectodomain but Occurs Independently of Enzymatically Generated ADP-Ribose or Cyclic ADP-Ribose
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31. Autoimmunity to CD38 and GAD in Type I and Type II diabetes: CD38 and HLA genotypes and clinical phenotypes
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32. Ectocellular in vitro and in vivo metabolism of cADP-ribose in cerebellum
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33. CD38 Signaling Regulates B Lymphocyte Activation via a Phospholipase C (PLC)-γ2-Independent, Protein Kinase C, Phosphatidylcholine-PLC, and Phospholipase D-Dependent Signaling Cascade
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35. CD157 plays a pivotal role in neutrophil transendothelial migration
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36. The prognostic value of CD38 expression in chronic lymphocytic leukaemia patients studied prospectively at diagnosis: a single institute experience
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37. Immunophenotyping of T Lymphocytes by Three-Color Flow Cytometry in Healthy Newborns, Children, and Adults
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39. Suppressed Insulin Signaling and Increased Apoptosis inCd38-Null Islets
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40. CD38 expression in B-chronic lymphocytic leukemia: association with clinical presentation and outcome in 155 patients.
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41. The modulated expression of Mo5, a human myelomonocytic plasma membrane antigen.
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42. Role of CD38 and Its Ligand in the Regulation of MHC-Nonrestricted Cytotoxic T Cells
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43. CD38 expressed on human monocytes: A coaccessory molecule in the superantigen-induced proliferation
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44. Peripheral blood CD38 expression predicts survival in B-cell chronic lymphocytic leukemia
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45. Mapping of the catalytic and epitopic sites of human CD38/NAD+ glycohydrolase to a functional domain in the carboxyl terminus
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46. CD38 as a prognostic factor in B cell chronic lymphocytic leukaemia (B‐CLL): Comparison of three approaches to analyze its expression
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47. CD38 expression as a prognostic indicator in chronic lymphocytic leukaemia
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48. Concentrative Uptake of Cyclic ADP-ribose Generated by BST-1+ Stroma Stimulates Proliferation of Human Hematopoietic Progenitors
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49. Immunologic activation during pregnancy: serial measurement of lymphocyte phenotype and serum activation molecules in HIV-infected and uninfected women
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50. Production of Calcium-Mobilizing Metabolites by a Novel Member of the ADP-Ribosyl Cyclase Family Expressed inSchistosoma mansoni,
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51. Characterization and localization of CD38 in the vertebrate eye
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52. The Making of a Leukocyte Receptor: Origin, Genes and Regulation of Human CD38 and Related Molecules
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53. Cleavage of CD14 on Human Gingival Fibroblasts Cocultured with Activated Neutrophils Is Mediated by Human Leukocyte Elastase Resulting in Down-Regulation of Lipopolysaccharide-Induced IL-8 Production
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54. Prognostic significance of CD38 and CD20 expression as assessed by quantitative flow cytometry in chronic lymphocytic leukaemia
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55. Stimulation of ADP‐Ribosyl Cyclase Activity of the Cell Surface Antigen CD38 by Zinc Ions Resulting from Inhibition of Its NAD+ Glycohydrolase Activity
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56. Prognostic significance of combined analysis of ZAP‐70 and CD38 in chronic lymphocytic leukemia
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57. Autoantibody Response to CD38 in Caucasian Patients With Type 1 and Type 2 Diabetes
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58. CD38 as a Therapeutic Target
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59. CD38 as a therapeutic target.
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60. CD38 binding to human myeloid cells is mediated by mouse and human CD31
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61. Signaling through murine CD38 is impaired in antigen receptor‐unresponsive B cells
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62. CXCR4 expression is associated with survival in familial chronic lymphocytic leukemia, but CD38 expression is not
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63. CD38 ligation plays a direct role in the induction of IL-1β, IL-6, and IL-10 secretion in resting human monocytes
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64. HIV-infected children with moderate/severe immune-suppression: changes in the immune system after highly active antiretroviral therapy
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65. NF-kappaB is required for CD38-mediated induction of Cgamma1 germline transcripts in murine B lymphocytes
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66. Expression of homing receptors and related molecules on human mast cells and basophils: a comparative analysis using multi‐color flow cytometry and toluidine blue/immunofluorescence staining techniques
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67. The CD3-γδε Transducing Module Mediates CD38-induced Protein-tyrosine Kinase and Mitogen-activated Protein Kinase Activation in Jurkat T Cells
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68. Death of T cell precursors in the human thymus: a role for CD38
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69. Extracellular cyclic ADP-ribose potentiates ACh-induced contraction in bovine tracheal smooth muscle
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77. CD38 Expression on CD8+ T Cells as a Prognostic Marker in Vertically HIV-Infected Pediatric Patients
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78. The lymphocyte surface antigen CD38 acts as a nicotinamide adenine dinucleotide glycohydrolase in human T lymphocytes
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79. Pancreatic Islet Cells Express BST-1, a CD38-like Surface Molecule Having ADP-Ribosyl Cyclase Activity
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80. CD38 ligation inhibits normal and leukemic myelopoiesis
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81. The structure of the Aplysia kurodai gene encoding ADP-ribosyl cyclase, a second-messenger enzyme
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82. Human CD38 and its ligand CD31 define a unique lamina propria T lymphocyte signaling pathway
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83. Stroma‐generated cyclic ADP‐ribose stimulates the expansion of early human hemopoietic progenitors by a paracrine interaction
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84. ADP-ribosyl cyclases generate two unusual adenine homodinucleotides with cytotoxic activity on mammalian cells
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85. Deficit of CD38/cyclic ADP-ribose is differentially compensated in hearts by gender
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86. Characterization of a CD38-like 78-kilodalton soluble protein released from B cell lines derived from patients with X-linked agammaglobulinemia.
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87. CD38 and ADP-ribosyl Cyclase Catalyze the Synthesis of a Dimeric ADP-ribose That Potentiates the Calcium-mobilizing Activity of Cyclic ADP-ribose
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88. Self‐aggregation of purified and membrane‐bound erythrocyte CD38 induces extensive decrease of its ADP‐ribosyl cyclase activity
    Elena Zocchi, Luisa Franco, Lucrezia Guida, Lesley J. Calder, Antonio DE FLORA · 1995 · FEBS Letters
89. Estrogen Increases CD38 Gene Expression and Leads to Differential Regulation of Adenosine Diphosphate (ADP)-Ribosyl Cyclase and Cyclic ADP-Ribose Hydrolase Activities in Rat Myometrium1
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90. Human CD38, a surface receptor, an enzyme, an adhesion molecule and not a simple marker.
    Ada Funaro, Fabio Malavasi · 1999 · PubMed
91. Association of CD38 Antigen Expression with Other Prognostic Parameters in Early Stages of Chronic Lymphocytic Leukemia
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92. Inhibition of the intrinsic NAD+ glycohydrolase activity of CD38 by carbocyclic NAD analogues
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93. Stage-specific expression of mouse BST-1/BP-3 on the early B and T cell progenitors prior to gene rearrangement of antigen receptor.
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94. Ligation of Cell Surface CD38 Protein with Agonistic Monoclonal Antibody Induces a Cell Growth Signal in Myeloid Leukemia Cells
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95. Genomic structure of human BST-1
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96. Association of CD38 with Nonmuscle Myosin Heavy Chain IIA and Lck Is Essential for the Internalization and Activation of CD38
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97. Inhibition of NAD+ Glycohydrolase and ADP-ribosyl Cyclase Activities of Leukocyte Cell Surface Antigen CD38 by Gangliosides
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98. Relationship between CD38 expression on peripheral blood T‐cells and monocytes, and response to antiretroviral therapy: A one‐year longitudinal study of a cohort of chronically infected ART‐naive HIV‐1+ patients
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99. CD38 induces apoptosis of a murine pro-B leukemic cell line by a tyrosine kinase-dependent but ADP-ribosyl cyclase- and NAD glycohydrolase-independent mechanism
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100. CD38 as a target of IB4 mAb carrying saporin-S6: design of an immunotoxin for ex vivo depletion of hematological CD38+ neoplasia.
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101. CD38-Mediated Signaling Events in Murine Pro-B Cells Expressing Human CD38 With or Without Its Cytoplasmic Domain
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102. Increases in soluble CD8 antigen in plasma, and CD8+ and CD8+CD38+ cells in human immunodeficiency virus type-1 infection
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103. CD38 expression level and pattern of expression remains a reliable and robust marker of progressive disease in chronic lymphocytic leukemia
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104. Molecular characterization of NADase-streptolysin O operon of hemolytic streptococci
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105. BP-3 alloantigen. A cell surface glycoprotein that marks early B lineage cells and mature myeloid lineage cells in mice.
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106. Expression of CD38 Gene, but Not of Mitochondrial Glycerol-3-Phosphate Dehydrogenase Gene, Is Impaired in Pancreatic Islets of GK Rats
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107. Retinoic acid-induced CD38 antigen as a target for immunotoxin-mediated killing of leukemia cells
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108. [28] Synthesis and hydrolysis of cyclic ADP-ribose by human leukocyte antigen CD38: Inhibition of hydrolysis by ATP and physiological significance
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109. Treatment of Post-Transplant Lymphomas with Anti-B-Cell Monoclonal Antibodies
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110. CD38 Is Required for the Peripheral Survival of Immunotolerogenic CD4+ Invariant NK T Cells in Nonobese Diabetic Mice
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111. Retinoic acid-induced CD38 antigen promotes leukemia cells attachment and interferon-γ/interleukin-1β-dependent apoptosis of endothelial cells: Implications in the etiology of retinoic acid syndrome
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112. A role for BP-3/BST-1 antigen in early T cell development
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113. Spatio-temporal propagation of Ca2+ signals by cyclic ADP-ribose in 3T3 cells stimulated via purinergic P2Y receptors
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114. Human CD38 interferes with HIV‐1 fusion through a sequence homologous to the V3 loop of the viral envelope glycoprotein gp120.
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115. Regulation of CD38 expression and function by steroid hormones in myometrium
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116. Direct Interaction of the CD38 Cytoplasmic Tail and the Lck SH2 Domain
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117. Chromosome aberrations evaluated by comparative genomic hybridization in B-cell chronic lymphocytic leukemia: correlation with CD38 expression.
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118. CD38 Gene Disruption Inhibits the Contraction Induced by .ALPHA.-Adrenoceptor Stimulation in Mouse Aorta
     Minori Mitsui‐Saito, Ichiro Kato, Shin Takasawa, Hiroshi Okamoto, Teruyuki Yanagisawa · 2003 · Journal of Veterinary Medical Science
119. Anti-CD38 autoantibodies: Characterisation in new-onset Type I diabetes and latent autoimmune diabetes of the adult (LADA) and comparison with other islet autoantibodies
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120. CD38 is expressed as noncovalently associated homodimers on the surface of murine B lymphocytes
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121. Protein-tyrosine phosphorylation by IgG1 subclass CD38 monoclonal antibodies is mediated through stimulation of the FcgammaII receptors in human myeloid cell lines
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122. Phenotypic mapping of human mesothelial cells.
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123. Subcellular Localization of Mammalian Type II Membrane Proteins
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124. Catalysis-associated Conformational Changes Revealed by Human CD38 Complexed with a Non-hydrolyzable Substrate Analog
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125. NAADP: A New Second Messenger Comes of Age
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126. Cyclic ADP-ribose metabolism in rat kidney: High capacity for synthesis in glomeruli
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127. Changes in CD38 Expression and ADP-Ribosyl Cyclase Activity in Rat Myometrium During Pregnancy: Influence of Sex Steroid Hormones1
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128. CD38 is associated with premenopausal and postmenopausal bone mineral density and postmenopausal bone loss
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129. Molecular cloning and functional expression of bovine spleen ecto-NAD+ glycohydrolase: structural identity with human CD38
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130. CD38 cleavage in fMLP- and IL-8-induced chemotaxis is dependent on p38 MAP kinase but independent of p44/42 MAP kinase
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131. CD38 Expression in Neutrophils From Patients With Localized Aggressive Periodontitis
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132. Extracellular NAD+ metabolism modulates osteoclastogenesis
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133. Correlation Between Cell Size and CD38 Expression in Chronic Lymphocytic Leukaemia
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134. A Cloned Rat CD38-Homologous Protein and Its Expression in Pancreatic Islets
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135. Independently Ligating CD38 and FcγRIIB Relays A Dominant Negative Signal to B Cells
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136. Ontogeny of Human Lymphocytes
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137. Association of phosphatidylinositol 3‐kinase with the photo‐oncogene product Cbl upon CD38 ligation by a specific monoclonal antibody in THP‐1 cells
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138. CD38 polymorphisms in Spanish patients with systemic lupus erythematosus
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139. Effects of the human CD38 glycoprotein on the early stages of the HIV‐1 replication cycle
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140. CD38 modifications in chronic lymphocytic leukemia: are they relevant?
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141. Probing ligand-induced conformational changes of human CD38
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142. Cyclic ADP‐ribose generation by CD38 improves human hemopoietic stem cell engraftment into NOD/SCID mice
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143. Evaluation of HIV-1 p24 Antigenemia and Level of CD8+CD38+ T cells as Surrogate Markers of HIV-1 RNA Viral Load in HIV-1-Infected Patients in Dakar, Senegal
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144. CD38 expression does not change in B-cell chronic lymphocytic leukemia
     Giovanni Francesco D'Arena, Giuseppe Nunziata, Giuseppe Coppola, Maria Luigia Vigliotti, Alfredo Tartarone, Nicola Carpinelli, Rosella Matera, Rosario Colella Bisogno, Giuseppe Pistolese, Nicola Di Renzo · 2002 · Blood
145. Potentiation of Chemotactic Peptide-Induced Superoxide Generation by CD38 Ligation in Human Myeloid Cell Lines
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146. Serum levels of different forms of soluble CD38 antigen in burned patients
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147. Overexpression of human CD38/ADP-ribosyl cyclase enhances acetylcholine-induced Ca2+ signalling in rodent NG108-15 neuroblastoma cells
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148. Immunotyping of blasts in human bone marrow
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149. Cycling G1 CD34 + /CD38 + Cells Potentiate the Motility and Engraftment of Quiescent G0 CD34 + /CD38 −/low Severe Combined Immunodeficiency Repopulating Cells
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150. Peripheral blood CD38 expression predicts time to progression in B-cell chronic lymphocytic leukemia after first-line therapy with high-dose chlorambucil.
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151. Investigation of the potential role of membrane CD38 in protection against cell death induced by HIV-1.
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152. Complex Gangliosides as Cell Surface Inhibitors for the Ecto-NAD+Glycohydrolase of CD38
     Miki Hara‐Yokoyama, Yasuko Nagatsuka, Osamu Katsumata, Fumitoshi Irie, Kenji Kontani, Shin-ichi Hoshino, Toshiaki Katada, Yasushi Ono, Junko Fujita‐Yoshigaki, Hiroshi Sugiya et al. · 2001 · Biochemistry
153. Complex Gangliosides as Cell Surface Inhibitors for the Ecto-NAD+ Glycohydrolase of CD38
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154. Prolonged In Vitro Exposure to Autoantibodies Against CD38 Impairs the Function and Survival of Human Pancreatic Islets
     Piero Marchetti, Alessandro Antonelli, Roberto Lupi, Lorella Marselli, Poupak Fallahi, Claudia Nesti, Germano Baj, Ele Ferrannini · 2002 · Diabetes
155. Fully human antibody MOR202 against CD38 for the treatment of multiple myeloma and other blood-borne malignancies
     Michael Tesar · 2007 · Journal of Clinical Oncology
156. Dendritic cells and follicular dendritic cells express a novel ligand for CD38 which influences their maturation and antibody responses
     Michelle Wykes, Lynette Beattie, G. Gordon MacPherson, Derek N.J. Hart · 2004 · Immunology
157. Novel localization of CD38 in perivascular sympathetic nerve terminals
     Lisa M. Smyth, Leanne T. Breen, Ilia A. Yamboliev, Violeta N. Mutafova–Yambolieva · 2006 · Neuroscience
158. Differential susceptibility of resting CD4+ T lymphocytes to a T-tropic and a macrophage (M)-tropic human immunodeficiency virus type 1 is associated with their surface expression of CD38 molecules
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159. Mitochondrial Dysfunction Induced by a Cytotoxic Adenine Dinucleotide Produced by ADP-ribosyl Cyclases from cADPR
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160. Modulation of CD157 expression in multi-lineage myeloid differentiation of promyelocytic cell lines
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161. Endothelin-1, superoxide and adeninediphosphate ribose cyclase in shark vascular smooth muscle
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162. CD38+ chronic lymphocytic leukaemia cells co-express high levels of ZAP-70 and are functionally distinct from their CD38− counter-parts
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163. Resting CD4+ T Cells with CD38+CD62L+ Produce Interleukin-4 Which Contributes to Enhanced Replication of T-Tropic Human Immunodeficiency Virus Type 1
     Haruko Horikoshi, Masanobu Kinomoto, Takeshi Kurosu, Satoshi Komoto, Miki Shiraga, Toru Otake, Tetsu Mukai, Kazuyoshi Ikuta · 2002 · Virology
164. cADP-ribose formation by blood platelets is not responsible for intracellular calcium mobilization
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165. Molecular Cloning, Expression, and Functional Characterization of a Novel Member of the CD38 Family of ADP-ribosyl Cyclases
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166. CD38 is a marker of human lacteals
     Inger Nina Farstad, Fabio Malavasi, Guttorm Haraldsen, Henrik Sverre Huitfeldt, Per Brandtzæg · 2002 · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
167. Functional role of glycosylation on the recombinant CD38/ADP-ribosyl cyclase in CHO cells
     Natesavelalar Chidambaram, Chan Fong Chang · 1998 · The International Journal of Biochemistry & Cell Biology
168. An Immature Rat Lymphocyte Marker CD157: Striking Differences in the Expression between Mice and Rats
     Mizue Seki, Susan P. Fairchild, Oliver A. Rosenwasser, Nobuhiko Tada, Kyuhei Tomonari · 2001 · Immunobiology
169. No evidence of diabetes‐specific CD38 (ADP ribosil cyclase/cyclic ADP‐ribose hydrolase) autoantibodies by liquid‐phase immunoprecipitation
     Valeria Sordi, Vito Lampasona, Silvia Cainarca, Ezio E. Bonifacio · 2005 · Diabetic Medicine
170. Anti-CD38 Autoimmunity in Children with Newly Diagnosed Type 1 Diabetes Mellitus
     Cinzia Pupilli, Alessandro Antonelli, Lorenzo Iughetti, Giuseppe d’Annunzio, Mario Cotellessa, M Vanelli, H. Okamoto, Renata Lorini, Ele Ferrannini · 2005 · Journal of Pediatric Endocrinology and Metabolism
171. Preliminary studies for an immunotherapeutic approach to the treatment of human myeloma using chimeric anti-CD38 antibody
     Freda K. Stevenson, AJ Bell, Rebecca Cusack · 1991 · Blood
172. Thymic hormone modulation of CD38 (T10) antigen on human cord blood lymphocytes
     Roberto Gerli, A Bertotto, Fabrizio Spinozzi, C Cernetti, Alessandra Battaglia, Roberto Falchetti, Fausto Grignani, Pietro Rambotti · 1987 · Clinical Immunology and Immunopathology
173. CD157 undergoes ligand-independent dimerization and colocalizes with caveolin in CHO and MCA102 fibroblasts
     Fubo Liang, Robert Zhong Qi, Chan Fong Chang · 2002 · Cellular Signalling
174. Cytoskeleton‐dependent inhibition of the ADP‐ribosyl cyclase activity of CD38 in thrombin‐stimulated platelets
     Mauro Torti, Enrico Tolnai Festetics, Alessandra Bertoni, Fabiola Sinigaglia, Cesare Balduini · 1998 · FEBS Letters
175. Expression and Activation of the Nonreceptor Tyrosine Kinase Tec in Human B Cells
     Akira Kitanaka, Hiroyuki Mano, Mary Ellen Conley · 1998 · Blood
176. Retrospective Analysis of CD38 Expression in 102 Patients with B-CLL with a Maximum Follow-Up of 18 Years: Incidence and Prognostic Significance
     Andreas Jakob, Jasmin Doll, Jürgen Schulte‐Mönting, Friedrich W. Hirsch · 2006 · Oncology Research and Treatment
177. Short peptides sensitize target cells to CTL specific for the MHC class Ib molecule, H2-M3
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