Arginase: A Multifaceted Enzyme Important in Health and Disease

Cites (257)

Items 201–257 of 257

1. The Role of Arginase 1 in Post-Stroke Immunosuppression and Ischemic Stroke Severity
   Ashley Brooke Petrone, Grant C. O’Connell, Michael Regier, Paul David Chantler, James W. Simpkins, Taura L. Barr · 2015 · Translational Stroke Research
2. Amino acid metabolism reflecting arginase activity is increased in patients with type 2 diabetes and associated with endothelial dysfunction
   Oskar Kövamees, Alexey S. Shemyakin, John Pernow · 2016 · Diabetes and Vascular Disease Research
3. Anti-leukemic mechanisms of pegylated arginase I in acute lymphoblastic T-cell leukemia
   Kevin D. Morrow, C P Hernandez, Patrick L. Raber, Luis Del Valle, Anna M. Wilk, S Majumdar, Dorota Danuta Wyczechowska, Krzysztof Reiss F, Paulo C. Rodrı́guez · 2012 · Leukemia
4. The role of the arginine metabolome in pain: implications for sickle cell disease
   Claudia R. Morris, Nitya Bakshi · 2016 · Journal of Pain Research
5. l-Citrulline Protects from Kidney Damage in Type 1 Diabetic Mice
   Maritza Josefina Romero, Lin Yao, Supriya Sridhar, Anil Bhatta, Huijuan Dou, Ganesan Ramesh, Michael W. Brands, David M. Pollock, Ruth B. Caldwell, Stephen D. Cederbaum et al. · 2013 · Frontiers in Immunology
6. The Muddle with MAG
   Marie T. Filbin · 1996 · Molecular and Cellular Neuroscience
7. IL-13 receptor α2-arginase 2 pathway mediates IL-13-induced pulmonary hypertension
   Won‐Kyung Cho, Chang‐Min Lee, Min‐Jong Kang, Yan Huang, Frank J. Giordano, Patty J. Lee, Terence K. Trow, Robert Homer, William C. Sessa, Jack Angel Elias et al. · 2012 · American Journal of Physiology-Lung Cellular and Molecular Physiology
8. Arginase Inhibition Reverses Endothelial Dysfunction, Pulmonary Hypertension, and Vascular Stiffness in Transgenic Sickle Cell Mice
   Jochen Steppan, Huong T. Tran, Valeriani R. Bead, Young Jun Oh, Gautam Sikka, Trinity Jude Bivalacqua, Arthur L. “Bud” Burnett, Dan E. Berkowitz, Lakshmi Santhanam · 2016 · Anesthesia & Analgesia
9. Arginase 1 Mediates Increased Blood Pressure and Contributes to Vascular Endothelial Dysfunction in Deoxycorticosterone Acetate-Salt Hypertension
   Haroldo A. Toque, Kênia Pedrosa Nunes, Modesto Rojas, Anil Bhatta, Lin Yao, Zhimin Xu, Maritza Josefina Romero, Robert Clinton Webb, Ruth B. Caldwell, Robert W. Caldwell · 2013 · Frontiers in Immunology
10. New Strategies for the Treatment of Pulmonary Hypertension in Sickle Cell Disease
    Claudia R. Morris · 2006 · Treatments in Respiratory Medicine
11. Paradoxical effect of l-arginine: Acceleration of endothelial cell senescence
    Fortunato Scalera, Ellen Ildicho Closs, Eva Flick, Jens Martens‐Lobenhoffer, Jean Boissel, Uwe Lendeckel, Anke Heimburg, Stefanie M. Bode‐Böger · 2009 · Biochemical and Biophysical Research Communications
12. Neuronal and Glial Responses to Polyamines in the Ischemic Brain
    Katsura Takano, Masato Ogura, Yoichi Nakamura, Yukio Yoneda · 2005 · Current Neurovascular Research
13. Mice deficient in Mkp-1 develop more severe pulmonary hypertension and greater lung protein levels of arginase in response to chronic hypoxia
    Yi Jin, Thomas J. Calvert, Bernadette Chen, Louis G. Chicoine, Mandar S Joshi, John Anthony Bauer, Liu Y, Leif Daniel Nelin · 2010 · American Journal of Physiology-Heart and Circulatory Physiology
14. Arginase inhibition prevents bleomycin-induced pulmonary hypertension, vascular remodeling, and collagen deposition in neonatal rat lungs
    Hartmut Grasemann, Rupinder Dhaliwal, Julijana Ivanovska, Crystal Kantores, Patrick Joseph McNamara, Jeremy A. Scott, Jaques Belik, Robert P. Jankov · 2015 · American Journal of Physiology-Lung Cellular and Molecular Physiology
15. Reduced Nitro-oxidative Stress and Neural Cell Death Suggests a Protective Role for Microglial Cells in TNFα −/− Mice in Ischemic Retinopathy
    Laura Stevenson, Nuria Matesanz, Liza M. Colhoun, Kevin S. Edgar, Adrian B. Devine, Tom A. Gardiner, Denise McDonald · 2010 · Investigative Ophthalmology & Visual Science
16. Angiotensin II limits NO production by upregulating arginase through a p38 MAPK–ATF-2 pathway
    Alia Shatanawi, Tahira Lemtalsi, Lin Yao, Chintan Patel, Ruth B. Caldwell, Robert W. Caldwell · 2014 · European Journal of Pharmacology
17. The vascular effects of different arginase inhibitors in rat isolated aorta and mesenteric arteries
    N. N. Huynh, EE Harris, Jaye P.F. Chin-Dusting, KL Andrews · 2008 · British Journal of Pharmacology
18. Extracellular Signal-regulated Kinase Mediates Expression of Arginase II but Not Inducible Nitric-oxide Synthase in Lipopolysaccharide-stimulated Macrophages
    Yi Jin, Liu Y, Leif Daniel Nelin · 2014 · Journal of Biological Chemistry
19. Arginase 2 Deficiency Prevents Oxidative Stress and Limits Hyperoxia-Induced Retinal Vascular Degeneration
    Jutamas Suwanpradid, Modesto Rojas, M. Ali Behzadian, Robert W. Caldwell, Ruth B. Caldwell · 2014 · PLoS ONE
20. Localization and differential expression of arginase II in the kidney of male and female mice
    Olivier Levillain, Sandra Balvay, S Peyrol · 2004 · Pflügers Archiv - European Journal of Physiology
21. Treatment effect of l-Norvaline on the sexual performance of male rats with streptozotocin induced diabetes
    Abhijit De, Mamta Farswan Singh, Vinod Singh, Veerma Ram, Shradha Bisht · 2015 · European Journal of Pharmacology
22. Obesity-induced vascular inflammation involves elevated arginase activity
    Lin Yao, Anil Bhatta, Zhimin Xu, Jijun Chen, Haroldo A. Toque, Yongjun Chen, Yimin Xu, Zsolt A Bagi, Rudolf Lucas, Yuqing Huo et al. · 2017 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
23. Plasma Amino Acids in Relation to Metabolic Control in Insulin‐Dependent Diabetic Children
    Lars Hagenfeldt, Gisela G Dahlquist, Bertil Persson · 1989 · Acta Paediatrica
24. Regulation of arginase II by interferon regulatory factor 3 and the involvement of polyamines in the antiviral response
    Nathalie Grandvaux, François Gaboriau, Jennifer Harris, Benjamin Robert tenOever, Rongtuan Lin, John B. Hiscott · 2005 · FEBS Journal
25. Arginase inhibition improves coronary microvascular function and reduces infarct size following ischaemia–reperfusion in a rat model
    Julia Grönros, Attila Kiss, M. Palmér, Christian Jung, Dan E. Berkowitz, John Pernow · 2013 · Acta Physiologica
26. Diabetic nephropathy is resistant to oral l -arginine or l -citrulline supplementation
    Hanning You, Ting Gao, Timothy K. Cooper, Sidney M. Morris, Alaa S. Awad · 2014 · American Journal of Physiology-Renal Physiology
27. Immunosuppressive treatment in dialysis patients
    P. Altieri · 2002 · Nephrology Dialysis Transplantation
28. Relationship between Arginase 1 and Arginase 2 levels and genetic polymorphisms with erectile dysfunction
    Riccardo Lacchini, Jaqueline Jóice Muniz, Y T D A Nobre, Adauto José Cologna, Antônio Carlos Pereira Martins, José Eduardo Tanus-Santos · 2015 · Nitric Oxide
29. Angiotensin II-Induced Arterial Thickening, Fibrosis and Stiffening Involves Elevated Arginase Function
    Anil Bhatta, Lin Yao, Haroldo A. Toque, Alia Shatanawi, Zhimin Xu, Ruth B. Caldwell, R. William Caldwell · 2015 · PLoS ONE
30. Chronic Oral Administration of the Arginase Inhibitor 2(S)‐amino‐6‐boronohexanoic Acid (ABH) Improves Erectile Function in Aged Rats
    Robert Segal, Johanna L. Hannan, Xiaopu Liu, Ömer Kutlu, Arthur L. “Bud” Burnett, Hunter C. Champion, Jae Hyung Kim, Jochen Steppan, Dan E. Berkowitz, Trinity Jude Bivalacqua · 2012 · Journal of Andrology
31. New approaches to the design and discovery of therapies to prevent erectile dysfunction
    Haroldo A. Toque, Robert W. Caldwell · 2014 · Expert Opinion on Drug Discovery
32. Impaired L-Arginine Uptake But Not Arginase Contributes to Endothelial Dysfunction in Rats With Chronic Kidney Disease
    Christopher R. Martens, James Matthew Kuczmarski, Shannon Liduina Lennon, David G. Edwards · 2013 · Journal of Cardiovascular Pharmacology
33. Arginase inhibition: a new treatment for preventing progression of established diabetic nephropathy
    Hanning You, Ting Gao, Timothy K. Cooper, Sidney M. Morris, Alaa S. Awad · 2015 · American Journal of Physiology-Renal Physiology
34. Treatment with polyamine oxidase inhibitor reduces microglial activation and limits vascular injury in ischemic retinopathy
    Chintan Patel, Zhimin Xu, Esraa Shosha, Xing Ji, Rudolf Lucas, Robert W. Caldwell, Ruth B. Caldwell, Subhadra Priya Narayanan · 2016 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
35. Arginase as a target for treatment of myocardial ischemia-reperfusion injury
    Yahor Tratsiakovich, Jiangning Yang, Adrian Thomas Gonon, Per-Ove B. Sjöquist, John Pernow · 2013 · European Journal of Pharmacology
36. Arginase inhibition enhances angiogenesis in endothelial cells exposed to hypoxia
    Lin Wang, Anil Bhatta, Haroldo A. Toque, Modesto Rojas, Lin Yao, Zhimin Xu, Chintan Patel, Ruth B. Caldwell, R. William Caldwell · 2014 · Microvascular Research
37. The combination of peripheral nerve grafts and acidic fibroblast growth factor enhances arginase I and polyamine spermine expression in transected rat spinal cords
    Huai‐Sheng Kuo, May J. Tsai, Ming-Chao Huang, Wen‐Cheng Huang, Meng‐Jen Lee, Wen‐Chun Kuo, Li-Hua You, Ka-Chun Szeto, I‐Lun Tsai, Wen-Chi Chang et al. · 2007 · Biochemical and Biophysical Research Communications
38. Deregulation of arginase induces bone complications in high-fat/high-sucrose diet diabetic mouse model
    A. Bhatta, Rajnikumar Sangani, R. Kolhe, H. Toque, Michael Cain, Abby Wong, Nicole Howie, Rahul S. Shinde, M. Elsalanty, Lin Yao et al. · 2015 · Molecular and Cellular Endocrinology
39. Arginase inhibition ameliorates adipose tissue inflammation in mice with diet-induced obesity
    Huan Hu, Ji‐Young Moon, Ji Hyung Chung, Oh Yoen Kim, Rina Yu, Min‐Jeong Shin · 2015 · Biochemical and Biophysical Research Communications
40. Hypoxia induces arginase II expression and increases viable human pulmonary artery smooth muscle cell numbers via AMPKα1 signaling
    Jianjing Xue, Leif Daniel Nelin, Bernadette Chen · 2017 · American Journal of Physiology-Lung Cellular and Molecular Physiology
41. Serine racemase inhibition induces nitric oxide-mediated neurovascular protection during cerebral ischemia
    Akihiro Watanabe, Tsutomu Sasaki, Toshiro Yukami, Hideaki Kanki, Manabu Sakaguchi, Hiroshi Takemori, Kazuo Kitagawa, Hideki Mochizuki · 2016 · Neuroscience
42. Modulation of nitric oxide synthase by arginase and methylated arginines during the acute phase of experimental multiple sclerosis
    Srdjan Ljubisavljević, Ivana R. Stojanović, Radmila Pavlović, Dusan T. Sokolovic, Dusica D. Pavlovic, Tatjana Cvetković, Ivana D. Stevanović · 2012 · Journal of the Neurological Sciences
43. Arginase depletes plasma l-arginine and decreases pulmonary vascular reserve during experimental pulmonary embolism
    John A. Watts, Michael A. Gellar, Mary-Beth K. Fulkerson, Sudeep K. Das, Jeffrey Allen Kline · 2011 · Pulmonary Pharmacology & Therapeutics
44. Apoptotic cell-derived factors induce arginase II expression in murine macrophages by activating ERK5/CREB
    Vera Barra, A. Kühn, Andreas von Knethen, Andreas Weigert, Bernhard Brüne · 2010 · Cellular and Molecular Life Sciences
45. Arginase II Knockout Mouse Displays a Hypertensive Phenotype Despite a Decreased Vasoconstrictory Profile
    Ngan Huynh, Karen L. Andrews, Geoffrey A. Head, Sacha M. L. Khong, Dmitry N. Mayorov, Andrew James Murphy, Gavin William Lambert, Helen Kiriazis, Qi Xu, Xiao‐Jun Du et al. · 2009 · Hypertension
46. Protective Role of Arginase II in Cerebral Ischemia and Excitotoxicity
    Abdullah Shafique Ahmad, Zahoor Ahmad Shah · 2016 · Journal of Neurology and Neuroscience
47. Control of G1 progression by D-type cyclins: key event for cell proliferation.
    Jun‐ya Kato · 1997 · PubMed
48. Increased arginase levels contribute to impaired perfusion after cardiopulmonary resuscitation
    Christian Jung, Felix Quitter, Michael Lichtenauer, Michael Fritzenwanger, Alexander Pfeil, Alexey S. Shemyakin, Marcus Franz, Hans Reiner Figulla, Ruediger Pfeifer, John Pernow · 2014 · European Journal of Clinical Investigation
49. Arginase in the Vascular Endothelium: Friend or Foe?
    Rudolf Lucas, David J. Fulton, Robert W. Caldwell, Maritza Josefina Romero · 2014 · Frontiers in Immunology
50. Impact of Arginase II on CBF in Experimental Cortical Impact Injury in Mice Using MRI
    Brittany R. Bitner, Danielle C Brink, Leela C Mathew, Robia G. Pautler, Claudia Sue Robertson · 2010 · Journal of Cerebral Blood Flow & Metabolism
51. Cecropia pachystachya extract attenuated the renal lesion in 5/6 nephrectomized rats by reducing inflammation and renal arginase activity
    Claudia do Carmo Maquiaveli, Edson Roberto da Silva, L. Costa Rosa, Heloı́sa Della Coletta Francescato, João Francisco Lucon Júnior, Cleonice G.A. da Silva, Dulce Elena Casarini, Fernanda Aparecida Ronchi, Terezila Machado Coimbra · 2014 · Journal of Ethnopharmacology
52. The Polyamine Inhibitor Alpha-Difluoromethylornithine Modulates Hippocampus-Dependent Function after Single and Combined Injuries
    Susanna Rosi, Ryan A. Ferguson, Kelly Fishman, Antiño R. Allen, Jacob Raber, John R. Fike · 2012 · PLoS ONE
53. The Importance of Nitric Oxide and Arginase in the Pathogenesis of Acute Neuroinflammation: Are Those Contra Players with the Same Direction?
    Srdjan Ljubisavljević, Ivana R. Stojanović, Radmila Pavlović, Dusica D. Pavlovic · 2014 · Neurotoxicity Research
54. T cells conditioned with MDSC show an increased anti-tumor activity after adoptive T cell based immunotherapy
    Patrick L. Raber, Rosa A. Sierra, Paul Thevenot, Zhang Shuzhong, Dorota Danuta Wyczechowska, Takumi Kumai, Esteban Celis, Paulo C. Rodrı́guez · 2016 · Oncotarget
55. Selective Up-Regulation of Arginase-1 in Coronary Arteries of Diabetic Patients
    Zsolt A Bagi, Attila Fehér, Huijuan Dou, Zuzana Brosková · 2013 · Frontiers in Immunology
56. Arginase inhibition protects against hypoxia-induced pulmonary arterial hypertension
    Wenjin Jiang, Bolin Sun, Song Xue-peng, Yanbo Zheng, Ligang Wang, Tao Wang, SHENG LIU · 2015 · Molecular Medicine Reports
57. Misregulation of the arginase pathway in tissues of spontaneously hypertensive rats
    Teddy Bagnost, Alain Berthelot, Magalie Alvergnas, Carole Miguet‐Alfonsi, Claire André, Yves Claude Guillaume, Céline Demougeot · 2009 · Hypertension Research