Normalization of the Vasculature for Treatment of Cancer and Other Diseases

Goel, Shom, Duda, Dan G., Xu, Lei, Munn, Lance L., Boucher, Yves, Fukumura, Dai, Jain, Rakesh K.·2011·Physiological Reviews

Cites (320)

Items 201–320 of 320

  1. ‘Accidental’ anti-angiogenic drugs
    Robert S. Kerbel, Alicia Viloria‐Petit, Giannoula Lakka Klement, Janusz W. Rak · 2000 · European Journal of Cancer
  2. Interstitial hypertension in carcinoma of uterine cervix in patients: possible correlation with tumor oxygenation and radiation response.
    Hyejin Roh, Yves Boucher, Shalom Kalnicki, Ralph Buchsbaum, William D. Bloomer, Rakesh K. Jain · 1991 · PubMed
  3. Interaction between Bevacizumab and Murine VEGF-A: A Reassessment
    Lanlan Yu, Xiumin Wu, Zhiyong Cheng, Chingwei V. Lee, Jennifer E. LeCouter, Claudio Campa, Germaine Fuh, Henry B. Lowman, Napoleone Ferrara · 2008 · Investigative Ophthalmology & Visual Science
  4. Host-Derived Angiopoietin-2 Affects Early Stages of Tumor Development and Vessel Maturation but Is Dispensable for Later Stages of Tumor Growth
    Patrick Nasarre, Markus Thomas, Karoline Kruse, Iris Helfrich, Vivien Wolter, Carleen Deppermann, Dirk Schadendorf, Gavin Thurston, Ulrike Fiedler, Hellmut G. Augustin · 2009 · Cancer Research
  5. Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content
    Marya F. McCarty, Ray Somcio, Oliver Stoeltzing · 2007 · Journal of Clinical Investigation
  6. Effects of the Dual Phosphatidylinositol 3-Kinase/Mammalian Target of Rapamycin Inhibitor NVP-BEZ235 on the Tumor Vasculature: Implications for Clinical Imaging
    Christian Schnell, Frédéric Stauffer, Peter Roland ALLEGRINI, Terence O’Reilly, Paul M.J. McSheehy, Celine Dartois, Michael Stumm, Robert M. Cozens, Amanda J. Littlewood-Evans, Carlos Garcia-Echeverria et al. · 2008 · Cancer Research
  7. Effect of Tumor Microenvironment Modulation on the Efficacy of Oncolytic Virus Therapy
    Kazuhiko Kurozumi, Jayson J Hardcastle, Roopa Thakur, Ming Yang, Gregory A. Christoforidis, Giulia Fulci, Fred H. Hochberg, Ralph Weissleder, William Edgar Carson, Ennio Antonio Chiocca et al. · 2007 · JNCI Journal of the National Cancer Institute
  8. Out of air is not out of action
    Donald Paul Bottaro, Lance A. Liotta · 2003 · Nature
  9. Thalidomide Radiosensitizes Tumors through Early Changes in the Tumor Microenvironment
    Réginald Ansiaux, Christine Baudelet, Bénédicte F. Jordan, Nelson Beghein, Pierre Sonveaux, Julie De Wever, Philippe Martinive, Vincent Grégoire, Olivier Féron, Bernard Gallez · 2005 · Clinical Cancer Research
  10. Direct Evidence that Bevacizumab, an Anti-VEGF Antibody, Up-regulates SDF1α, CXCR4, CXCL6, and Neuropilin 1 in Tumors from Patients with Rectal Cancer
    Lei Xu, Dan Gabriel Duda, Emmanuelle di Tomaso, Marek Ancukiewicz, Daniel C. Chung, Gregory Yves Lauwers, Rekha Samuel, Paul C. Shellito, Brian G. Czito, Pei‐Chun Lin et al. · 2009 · Cancer Research
  11. A New Perspective on Tumor Endothelial Cells: Unexpected Chromosome and Centrosome Abnormalities
    Kyoko Hida, Michael Klagsbrun · 2005 · Cancer Research
  12. Systemic anti-VEGF treatment strongly reduces skin inflammation in a mouse model of psoriasis
    Helia B. Schönthaler, Reto Huggenberger, Stefanie K. Wculek, Michael J. Detmar, Erwin Friedrich Wagner · 2009 · Proceedings of the National Academy of Sciences
  13. Disease Course Patterns After Discontinuation of Bevacizumab: Pooled Analysis of Randomized Phase III Trials
    David Miles, Nadia Harbeck, Bernard J. Escudier, Herbert I. Hurwitz, Leonard B. Saltz, Eric Van Cutsem, Jim Cassidy, Barbara Mueller, Florin Sirzén · 2010 · Journal of Clinical Oncology
  14. Double Antiangiogenic Protein, DAAP, Targeting VEGF-A and Angiopoietins in Tumor Angiogenesis, Metastasis, and Vascular Leakage
    Young Jun Koh, Hak-Zoo Kim, Seong-Ik Hwang, Jeung Eun Lee, Nuri Oh, Keehoon Jung, Minah Kim, Kyung Eun Kim, Homin Kim, Nam Kyu Lim et al. · 2010 · Cancer Cell
  15. PlGF Blockade Does Not Inhibit Angiogenesis during Primary Tumor Growth
    Carlos Bais, Xiumin Wu, Jenny J. Yao, Suya Yang, Yongping Crawford, Krista M. McCutcheon, Christine Tan, Ganesh A. Kolumam, Jean-Michel Vernes, Jeffrey Eastham‐Anderson et al. · 2010 · Cell
  16. Nelfinavir Down-regulates Hypoxia-Inducible Factor 1α and VEGF Expression and Increases Tumor Oxygenation: Implications for Radiotherapy
    Nabendu Pore, Anjali Gupta, George J. Cerniglia, Zibin Jiang, Eric J. Bernhard, Sydney M. Evans, Cameron J. Koch, Stephen M. Hahn, Amit M. Maity · 2006 · Cancer Research
  17. A Human Monoclonal Anti-ANG2 Antibody Leads to Broad Antitumor Activity in Combination with VEGF Inhibitors and Chemotherapy Agents in Preclinical Models
    Jeffrey L. Brown, Zhu Alexander Cao, Maria C. Pinzon-Ortiz, Jane Kendrew, Corinne Reimer, Shenghua Wen, Joe Q. Zhou, Mohammad A. Tabrizi, Steve C. Emery, Brenda McDermott et al. · 2010 · Molecular Cancer Therapeutics
  18. Telomerized human microvasculature is functional in vivo
    Jiwei Yang, Usha Nagavarapu, Kenneth Relloma, Michael D. Sjaastad, William C. Moss, Antonino Passaniti, G. Scott Herron · 2001 · Nature Biotechnology
  19. What brings pericytes to tumor vessels?
    Rakesh K. Jain, Michael F. Booth · 2003 · Journal of Clinical Investigation
  20. Transport of fluid and macromolecules in tumors. IV. A microscopic model of the perivascular distribution
    Laurence T. Baxter, Rakesh K. Jain · 1991 · Microvascular Research
  21. Tumor Vascular Changes Mediated by Inhibition of Oncogenic Signaling
    Naseer Qayum, Ruth J. Muschel, Jae Hong Im, Lukxmi Balathasan, Cameron J. Koch, Sonal K. Patel, William Gillies McKenna, Eric J. Bernhard · 2009 · Cancer Research
  22. In vivo wide-area cellular imaging by side-view endomicroscopy
    Pilhan Kim, Euiheon Chung, Hiroshi Yamashita, Kenneth E. Hung, Atsushi Mizoguchi, Raju Kucherlapati, Dai Fukumura, Rakesh K Jain, Seok Hyun Yun · 2010 · Nature Methods
  23. What brings pericytes to tumor vessels?
    Rakesh K. Jain, Michael F. Booth · 2003 · Journal of Clinical Investigation
  24. Specifically Targeting Angiopoietin-2 Inhibits Angiogenesis, Tie2-Expressing Monocyte Infiltration, and Tumor Growth
    Hanhua Huang, Jing-Yu Lai, Janet Do, Dingguo Liu, Lingna Li, Joselyn Del Rosario, Venkata Ramana Doppalapudi, Steven Robert Pirie-Shepherd, Nancy Levin, Curt W. Bradshaw et al. · 2011 · Clinical Cancer Research
  25. VEGF as a Marker for Outcome Among Advanced Breast Cancer Patients Receiving anti-VEGF Therapy with Bevacizumab and Vinorelbine Chemotherapy
    Harold J. Burstein, Yu‐Hui Chen, Leroy M. Parker, Jennifer Savoie, Jerry Younger, Irene Kuter, Paula D. Ryan, Judy Ellen Garber, Helen Chen, Susana M. Campos et al. · 2008 · Clinical Cancer Research
  26. Improved Intratumoral Oxygenation Through Vascular Normalization Increases Glioma Sensitivity to Ionizing Radiation
    Mackenzie C. McGee, John Blair Hamner, Regan Frances Williams, Shannon F. Rosati, Thomas L. Sims, Catherine Y. Ng, M. Waleed Gaber, Christopher R. Calabrese, Jianrong Wu, Amit Chunilal Nathwani et al. · 2010 · International Journal of Radiation Oncology*Biology*Physics
  27. Tumor–host interactions in the gallbladder suppress distal angiogenesis and tumor growth: Involvement of transforming growth factor β1
    Takeshi Gohongi, Dai Fukumura, Yves Boucher, Chae‐Ok Yun, Gerald A. Soff, Carolyn C. Compton, Takeshi Todoroki, Rakesh K. Jain · 1999 · Nature Medicine
  28. Impact of Angiogenesis Inhibition by Sunitinib on Tumor Distribution of Temozolomide
    Qingyu Stephanie Zhou, Ping Guo, James M. Gallo · 2008 · Clinical Cancer Research
  29. Effective Suppression of Vascular Network Formation by Combination of Antibodies Blocking VEGFR Ligand Binding and Receptor Dimerization
    Denis Tvorogov, Andrey Anisimov, Wei Zheng, Veli‐Matti Leppänen, Tuomas Tammela, Simonas Laurinavičius, Wolfgang Holnthoner, Hanna Heloterä, Tanja Holopainen, Michael Jeltsch et al. · 2010 · Cancer Cell
  30. Angiopoietin-2 Interferes with Anti-VEGFR2–Induced Vessel Normalization and Survival Benefit in Mice Bearing Gliomas
    Chae, Sung-Suk, Kamoun, Walid S., Farrar, Christian T., Kirkpatrick, Nathaniel D., Niemeyer, Elisabeth, de Graaf, Annemarie M.A., Sorensen, A. Gregory, Munn, Lance L., Jain, Rakesh K., Fukumura, Dai · 2010 · Clinical Cancer Research
  31. Onset of Abnormal Blood and Lymphatic Vessel Function and Interstitial Hypertension in Early Stages of Carcinogenesis
    Jeroen Hagendoorn, Ricky T. Tong, Dai Fukumura, Qingcong Lin, Jennifer Lobo Shah, Timothy P. Padera, Lei Xu, Raju Kucherlapati, Rakesh K. Jain · 2006 · Cancer Research
  32. Differential CD146 Expression on Circulating Versus Tissue Endothelial Cells in Rectal Cancer Patients: Implications for Circulating Endothelial and Progenitor Cells As Biomarkers for Antiangiogenic Therapy
    Dan Gabriel Duda, Kenneth Stuart Cohen, Emmanuelle di Tomaso, Patrick Au, Rachael J. Klein, David T. Scadden, Christopher G. Willett, Rakesh K. Jain · 2006 · Journal of Clinical Oncology
  33. αvβ3/αvβ5 Integrins-FAK-RhoB: A Novel Pathway for Hypoxia Regulation in Glioblastoma
    Nicolas Skuli, Sylvie Monferran, Caroline Delmas · 2009 · Cancer Research
  34. Antiangiogenic Approaches to Age-Related Macular Degeneration Today
    Neil M. Bressler · 2009 · Ophthalmology
  35. Tumor oxygenation in hormone-dependent tumors during vascular endothelial growth factor receptor-2 blockade, hormone ablation, and chemotherapy.
    Nils Hansen‐Algenstaedt, Brian R. Stoll, Timothy P. Padera, Dennis E. J. G. J. Dolmans, Daniel J. Hicklin, Dai Fukumura, Rakesh K. Jain · 2000 · PubMed
  36. Epidermal Growth Factor Receptor Inhibition Modulates the Microenvironment by Vascular Normalization to Improve Chemotherapy and Radiotherapy Efficacy
    George J. Cerniglia, Nabendu Pore, Jeff H. Tsai, Susan M. Schultz, Rosemarie Mick, Regine Choe, Xiaoman Xing, Turgut Durduran, Arjun G. Yodh, Sydney M. Evans et al. · 2009 · PLoS ONE
  37. A systems approach to cancer therapy
    Beverly A. Teicher · 1996 · Cancer and Metastasis Reviews
  38. Taming Vessels to Treat Cancer
    Rakesh K. Jain · 2008 · Scientific American
  39. Anti–Vascular Endothelial Growth Factor Therapies as a Novel Therapeutic Approach to Treating Neurofibromatosis-Related Tumors
    Hon Kit Wong, Johanna Lahdenranta, Walid S. Kamoun, Annie W. Chan, Andrea I. McClatchey, Scott Randall Plotkin, Rakesh K. Jain, Emmanuelle di Tomaso · 2010 · Cancer Research
  40. Upfront, randomized, phase 2 trial of sorafenib versus sorafenib and low‐dose interferon alfa in patients with advanced renal cell carcinoma
    Eric W. Jonasch, Paul Gettys Corn, Lance C. Pagliaro, Carla L. Warneke, Marcella M. Johnson, Pheroze Tamboli, Chaan S. Ng, Ana M. Aparicio, Robynne G. Ashe, John J. Wright et al. · 2009 · Cancer
  41. Choriocarcinoma: Transfilter Stimulation of Vasoproliferation in the Hamster Cheek Pouch—Studied by Light and Electron Microscopy 2
    Robert L. Ehrmann, Mogens Knoth · 1968 · JNCI Journal of the National Cancer Institute
  42. COUP-TFII regulates tumor growth and metastasis by modulating tumor angiogenesis
    Jun Qin, Xinpu Chen, Xin Xie, Ming‐Jer Tsai, Sophia Y. Tsai · 2010 · Proceedings of the National Academy of Sciences
  43. VEGF and VEGF Receptor-1 Concentration in Vestibular Schwannoma Homogenates Correlates to Tumor Growth Rate
    Per Cay??-Thomasen, Kim Werther, Amarnadh Nalla, Thorkild C. B g-Hansen, Hans Jørgen Nielsen, Sven‐Eric Stangerup, Jens Thomsen · 2005 · Otology & Neurotology
  44. Antiangiogenic therapy for normalization of atherosclerotic plaque vasculature: a potential strategy for plaque stabilization
    Jain, Rakesh K, Finn, Aloke V, Kolodgie, Frank D, Gold, Herman K, Virmani, Renu · 2007 · Nature Clinical Practice Cardiovascular Medicine
  45. PDGF-C Induces Maturation of Blood Vessels in a Model of Glioblastoma and Attenuates the Response to Anti-VEGF Treatment
    Emmanuelle di Tomaso, Nyall R. London, Daniel G. Fuja, James J. Logie, James A. Tyrrell, Walid S. Kamoun, Lance L. Munn, Rakesh K. Jain · 2009 · PLoS ONE
  46. Pharmacodynamic-mediated reduction of temozolomide tumor concentrations by the angiogenesis inhibitor TNP-470.
    Jun Ma, Sharon K. Pulfer, Shao Li, Jianxiong Chu, Ken L. Reed, James M. Gallo · 2001 · PubMed
  47. Tumor microvascular changes in antiangiogenic treatment: Assessment by magnetic resonance contrast media of different molecular weights
    Karl Turetschek, Anda Preda, Viktor Novikov, Robert C. Brasch, Hanns Joachim Weinmann, Patrick Wunderbaldinger, Timothy P. L. Roberts · 2004 · Journal of Magnetic Resonance Imaging
  48. Ultrastructural localization of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) to the abluminal plasma membrane and vesiculovacuolar organelles of tumor microvascular endothelium.
    QU- HONG, Janice A. Nagy, Donald R. Senger, Harold F. Dvorak, Ann M. Dvořàk · 1995 · Journal of Histochemistry & Cytochemistry
  49. Lessons From the Adjuvant Bevacizumab Trial on Colon Cancer: What Next?
    Eric Van Cutsem, Diether Lambrechts, Hans Prenen, Rakesh K. Jain, Peter Carmeliet · 2010 · Journal of Clinical Oncology
  50. Geometric Resistance and Microvascular Network Architecture of Human Colorectal Carcinoma
    Joanne R. Less, Posner Mc, Thomas C. Skalak, Norman Wolmark, Rakesh K. Jain · 1997 · Microcirculation
  51. The role of hypoxia and acidosis in promoting metastasis and resistance to chemotherapy
    Katie DeClerck · 2009 · Frontiers in bioscience
  52. Angiogenesis and Oncogenesis
    Pietro M. Gullino · 1978 · JNCI Journal of the National Cancer Institute
  53. Differential response of primary tumor versus lymphatic metastasis to VEGFR-2 and VEGFR-3 kinase inhibitors cediranib and vandetanib
    Timothy P. Padera, Angera H. Kuo, Tohru Hoshida, Shan Liao, Jennifer Lobo Shah, Kevin Robert Kozak, Dai Fukumura, Rakesh K. Jain · 2008 · Molecular Cancer Therapeutics
  54. Palomid 529, a Novel Small-Molecule Drug, Is a TORC1/TORC2 Inhibitor That Reduces Tumor Growth, Tumor Angiogenesis, and Vascular Permeability
    Qi Xue, Benjamin David Hopkins, Carole A. Perruzzi, Durga Udayakumar, David Sherris, Laura E. Benjamin · 2008 · Cancer Research
  55. Effect of Inhibition of Vascular Endothelial Growth Factor Signaling on Distribution of Extravasated Antibodies in Tumors
    Tsutomu Nakahara, Scott Michael Norberg, David R. Shalinsky, Dana D. Hu‐Lowe, Donald M. McDonald · 2006 · Cancer Research
  56. Class 1A PI3K regulates vessel integrity during development and tumorigenesis
    Tina L. Yuan, Hak Soo Choi, Aya Matsui, Cyril H. Benes, Eugene Lifshits, Ji Luo, John V. Frangioni, Lewis C. Cantley · 2008 · Proceedings of the National Academy of Sciences
  57. Plasma Soluble VEGFR-1 Is a Potential Dual Biomarker of Response and Toxicity for Bevacizumab with Chemoradiation in Locally Advanced Rectal Cancer
    Dan Gabriel Duda, Christopher G. Willett, Marek Ancukiewicz, Emmanuelle di Tomaso, Mira Shah, Brian G. Czito, Rex C. Bentley, Martin H. Poleski, Gregory Yves Lauwers, Madeline D. Carroll et al. · 2010 · The Oncologist
  58. Association of diastolic blood pressure (dBP) ≥ 90 mmHg with overall survival (OS) in patients treated with axitinib (AG- 013736)
    Brian I. Rini, Joan H. Schiller, John P. Fruehauf, Ezra E.W. Cohen, Jamal Tarazi, Brad Rosbrook, Alejandro Daniel Ricart, Anthony J. Olszanski, S. Kim, Jean‐Philippe Spano · 2008 · Journal of Clinical Oncology
  59. Simultaneous imaging of tumor oxygenation and microvascular permeability using Overhauser enhanced MRI
    Shingo Matsumoto, Hironobu Yasui, Sonny Batra et al. · 2009 · Proceedings of the National Academy of Sciences
  60. Segmental Heterogeneity of Vasa Vasorum Neovascularization in Human Coronary Atherosclerosis
    Mario Gössl, Daniele Versari, Heike Annelie Hildebrandt, Thomas Bajanowski, Giuseppe Sangiorgi, Raimund Erbel, Erik L. Ritman, Lilach O. Lerman, Amir Lerman · 2010 · JACC. Cardiovascular imaging
  61. Tumor Vascular Maturation and Improved Drug Delivery Induced by Methylselenocysteine Leads to Therapeutic Synergy with Anticancer Drugs
    Arup Bhattacharya, Mukund Seshadri, Steven D. Oven, Károly Tóth, Mary M. Vaughan, Youcef M. Rustum · 2008 · Clinical Cancer Research
  62. Differential effect of sunitinib on the distribution of temozolomide in an orthotopic glioma model
    Qingyu Stephanie Zhou, James M. Gallo · 2008 · Neuro-Oncology
  63. Potentiation of cytotoxic therapies by TNP-470 and minocycline in mice bearing EMT-6 mammary carcinoma
    Beverly A. Teicher, Sylvia A. Holden, Norman P. Dupuis, Yoshihiro Kakeji, Masahiko Ikebe, Yasunori Emi, Donna A. Goff · 1995 · Breast Cancer Research and Treatment
  64. Neovascularization Induced by Intraocular Xenografts of Normal, Preneoplastic, and Neoplastic Mouse Mammary Tissues
    Michael A. Gimbrone, Pietro M. Gullino · 1976 · JNCI Journal of the National Cancer Institute
  65. Baseline Vascular Endothelial Growth Factor Concentration as a Potential Predictive Marker of Benefit from Vandetanib in Non–Small Cell Lung Cancer
    Emer O. Hanrahan, Anderson Joseph Ryan, Helen Mann, Sarah J. Kennedy, Peter B. Langmuir, Ronald B. Natale, Roy S. Herbst, Bruce Evan Johnson, John Victor Heymach · 2009 · Clinical Cancer Research
  66. Metronomic gemcitabine suppresses tumour growth, improves perfusion, and reduces hypoxia in human pancreatic ductal adenocarcinoma
    Karen K. Cham, Jennifer H.E. Baker, Karam S. Takhar et al. · 2010 · British Journal of Cancer
  67. PDGF-D Improves Drug Delivery and Efficacy via Vascular Normalization, But Promotes Lymphatic Metastasis by Activating CXCR4 in Breast Cancer
    Jieqiong Liu, Shan Liao, Yuhui Huang, Rekha Samuel, Tony Shi, Kamila Naxerova, Peigen Huang, Walid S. Kamoun, Rakesh K. Jain, Dai Fukumura et al. · 2011 · Clinical Cancer Research
  68. Ocular Angiogenesis
    Medha Rajappa, Parul Saxena, Jasbir Kaur · 2010 · Advances in clinical chemistry
  69. Immunohistochemical Demonstration of Vascular Endothelial Growth Factor in Vestibular Schwannomas Correlates to Tumor Growth Rate
    Per Cayé‐Thomasen, Lone Baandrup, Grete Krag Jacobsen · 2003 · The Laryngoscope
  70. Vascular remodelling of an arterio-venous blood vessel network during solid tumour growth
    Michael Welter, K. Bartha, Heiko Rieger · 2009 · Journal of Theoretical Biology
  71. Flow Correlated Percolation during Vascular Remodeling in Growing Tumors
    Deok‐Sun Lee, Heiko Rieger, K. Bartha · 2006 · Physical Review Letters
  72. High-grade glioma before and after treatment with radiation and Avastin: Initial observations
    Ingeborg Fischer, Clare Helen Cunliffe, Robert John Bollo, Shahzad Raza, David Monoky, Luis A. Chiriboga, Erik C. Parker, John G. Golfinos, Patrick John Kelly, Edmond A. Knopp et al. · 2008 · Neuro-Oncology
  73. Potentiation of cyclophosphamide chemotherapy using the anti-angiogenic drug thalidomide: Importance of optimal scheduling to exploit the ‘normalization’ window of the tumor vasculature
    Jérôme Segers, Vincent Di Fazio, Réginald Ansiaux, Philippe Martinive, Olivier Féron, Pierre E. Wallemacq, Bernard Gallez · 2006 · Cancer Letters
  74. Platelet-Derived Growth Factor Receptor-β Constitutive Activity Promotes Angiogenesis In Vivo and In Vitro
    Peetra Ulrica Magnusson, Camilla Looman, Aive Åhgren, Yan Ling Wu, Lena Claesson, Rainer Lothar Heuchel · 2007 · Arteriosclerosis Thrombosis and Vascular Biology
  75. Increased Expression of α6 Integrin in Endothelial Cells Unveils a Proangiogenic Role for Basement Membrane
    Luca Primo, Giorgio Seano, Cristina Roca, Federica Maione, Paolo Armando Gagliardi, Roberto Sessa, Marianna Martinelli, Enrico Giraudo, Laura di Blasio, Federico Bussolino · 2010 · Cancer Research
  76. TGF-β Blockade Controls Ascites by Preventing Abnormalization of Lymphatic Vessels in Orthotopic Human Ovarian Carcinoma Models
    Shan Liao, Jieqiong Liu, Peichun Lin, Tony Shi, Rakesh K. Jain, Lei Xu · 2011 · Clinical Cancer Research
  77. Combined therapy of local and metastatic 4T1 breast tumor in mice using SU6668, an inhibitor of angiogenic receptor tyrosine kinases, and the immunostimulator B7.2-IgG fusion protein.
    Xiaojun Huang, Michael K.K. Wong, Huiming Yi, Simon C. Watkins, Alexander Laird, Stanley F. Wolf, Elieser Gorelik · 2002 · PubMed
  78. Effective contribution of transplanted vascular progenitor cells derived from embryonic stem cells to adult neovascularization in proper differentiation stage
    Takami Yurugi-Kobayashi, Hiroshi Itoh, Jun K. Yamashita · 2003 · Blood
  79. The farnesyltransferase inhibitor L744,832 reduces hypoxia in tumors expressing activated H-ras.
    Elizabeth Cohen‐Jonathan Moyal, Sydney M. Evans, Cameron J. Koch, Ruth J. Muschel, William Gillies McKenna, Junmin Wu, Eric J. Bernhard · 2001 · PubMed
  80. Mini‐review: Overcoming tumor‐intrinsic resistance to immune effector function
    Ruth Ganß, Bernd Arnold, Günter Joachim Hämmerling · 2004 · European Journal of Immunology
  81. The farnesyltransferase inhibitor R115777 reduces hypoxia and matrix metalloproteinase 2 expression in human glioma xenograft.
    Caroline Delmas, Dave W. End, Philippe Rochaix, Gilles Favre, Christine Toulas, Elizabeth Cohen‐Jonathan Moyal · 2003 · PubMed
  82. Study of tumor blood perfusion and its variation due to vascular normalization by anti-angiogenic therapy based on 3D angiogenic microvasculature
    Jie Wu, Quan Long, Shixiong Xu, Anwar R. Padhani · 2009 · Journal of Biomechanics
  83. Angiopoietin-2-Driven Vascular Remodeling in Airway Inflammation
    Sébastien P. Tabruyn, Katharine Colton, Tohru Morisada, Jonas Fuxe, Stanley J. Wiegand, Gavin Thurston, Anthony J. Coyle, Jane R. Connor, Donald M. McDonald · 2010 · American Journal Of Pathology
  84. VEGF-A promotes intussusceptive angiogenesis in the developing chicken chorioallantoic membrane
    Oliver Baum, Florian Suter, Bernhard Gerber · 2010 · Microcirculation
  85. Antisense hypoxia‐inducible factor 1α gene therapy enhances the therapeutic efficacy of doxorubicin to combat hepatocellular carcinoma
    Fengjun Liu, Peijun Wang, Xian Li Jiang, Gang Tan, Haiquan Qiao, Hongchi Jiang, Geoffrey Wayne Krissansen, Xueying Sun · 2008 · Cancer Science
  86. Antiangiogenic treatment (TNP-470/minocycline) increases tissue levels of anticancer drugs in mice bearing Lewis lung carcinoma.
    Beverly A. Teicher, N. P. Dupuis, Megan Robinson · 1995 · PubMed
  87. The scientific contributions of M. Judah Folkman to cancer research
    Bruce R. Zetter · 2008 · Nature reviews. Cancer
  88. Antiangiogenesis Targeting Tumor Microenvironment Synergizes Glucuronide Prodrug Antitumor Activity
    Juan Ting-Yi, Steve R. Roffler, Hsien-San Hou, Shih‐Ming Huang, Kai‐Chuan Chen, Yu-Lin Leu, Zeljko M. Prijovich, Cheng‐Ping Yu, Chang‐Chieh Wu, Guang‐Huan Sun et al. · 2009 · Clinical Cancer Research
  89. Inhibition of TGF-β modulates macrophages and vessel maturation in parallel to a lowering of interstitial fluid pressure in experimental carcinoma
    Alexei V. Salnikov, Pernilla Roswall, Christian Sundberg, Humphrey Gardner, Nils‐Erik Heldin, Kristofer Rubin · 2005 · Laboratory Investigation
  90. Myocyte loss in chronic heart failure
    Neil B. Rayment, Aldwyn J. Haven, Brendan Patrick Madden, Andrew J. Murday, R. J. Trickey, Martin J. Shipley, Michael J. Davies, David R. Katz · 1999 · The Journal of Pathology
  91. Inhibition of Rho pathways induces radiosensitization and oxygenation in human glioblastoma xenografts
    Isabelle Ader, Caroline Delmas, Jacques Bonnet · 2003 · Oncogene
  92. A Safety and Survival Analysis of Neoadjuvant Bevacizumab with Standard Chemoradiation in a Phase I/II Study Compared with Standard Chemoradiation in Locally Advanced Rectal Cancer
    Christopher G. Willett, Dan Gabriel Duda, Marek Ancukiewicz, Mira Shah, Brian G. Czito, Rex C. Bentley, Martin H. Poleski, Hiroshi Fujita, Gregory Yves Lauwers, Madeline D. Carroll et al. · 2010 · The Oncologist
  93. The neurofibromatoses. Part 2: NF2 and schwannomatosis.
    Christine Lu‐Emerson, Scott Randall Plotkin · 2009 · PubMed
  94. In vivo quantification of microvessels in clinically uninvolved psoriatic skin and in normal skin
    Sunita Hern, Peter S Mortimer · 2007 · British Journal of Dermatology
  95. Non-Uniform Plasma Leakage Affects Local Hematocrit and Blood Flow: Implications for Inflammation and Tumor Perfusion
    Chenghai Sun, Rakesh K. Jain, Lance L. Munn · 2007 · Annals of Biomedical Engineering
  96. Blood Vessel Morphologic Changes Depicted with MR Angiography during Treatment of Brain Metastases: A Feasibility Study
    Elizabeth Bullitt, Nancy U. Lin, Jeffery Keith Smith · 2007 · Radiology
  97. Randomized phase II multicenter study of the efficacy and safety of sunitinib on the 4/2 versus continuous dosing schedule as first-line therapy of metastatic renal cell carcinoma: Renal EFFECT Trial.
    Robert John Motzer, Thomas E. Hutson, Mark R. Olsen · 2011 · Journal of Clinical Oncology
  98. Expression of Angiogenic Growth Factors in Acoustic Neurinoma
    Jürgen Brieger, Anan Bedavanija, Hans‐Anton Lehr · 2003 · Acta Oto-Laryngologica
  99. Suramin Treatment of Human Glioma Xenografts; Effects on Tumor Vasculature and Oxygenation Status
    H. J. J. A. Bernsen, Paul F.J.W. Rijken, Johannes P. W. Peters · 1999 · Journal of Neuro-Oncology
  100. Identification of Interferon-β-Stimulated Genes that Inhibit Angiogenesis In Vitro
    Kevin L. Taylor, Douglas W. Leaman, Ronald Grane · 2008 · Journal of Interferon & Cytokine Research
  101. Continuous Delivery of IFN-β Promotes Sustained Maturation of Intratumoral Vasculature
    Paxton Vandiver Dickson, John Blair Hamner, Christian J. Streck, Catherine Y. Ng, M. Beth McCarville, Christopher R. Calabrese, Richard J. Gilbertson, Clinton F. Stewart, Christy Wilson, M. Waleed Gaber et al. · 2007 · Molecular Cancer Research
  102. Inhibition of Colon Cancer Growth by Methylselenocysteine-Induced Angiogenic Chemomodulation Is Influenced by Histologic Characteristics of the Tumor
    Arup Bhattacharya, Károly Tóth, Arindam Sen, Mukund Seshadri, Shousong Cao, Farukh A. Durrani, Erik B. Faber, Elizabeth A. Repasky, Youcef M. Rustum · 2009 · Clinical Colorectal Cancer
  103. Anti‐tumor activity and tumor vessel normalization by the vascular endothelial growth factor receptor tyrosine kinase inhibitor KRN951 in a rat peritoneal disseminated tumor model
    Eri Taguchi, Kazuhide Nakamura, Toru Miura · 2008 · Cancer Science
  104. Androgens modulate the balance between VEGF and angiopoietin expression in prostate epithelial and smooth muscle cells
    Christian Richard, Gilbert Kim, Yasuhiro Koikawa, Sarah N. Salm, Akira Tsujimura, E. Lynette Wilson, David Moscatelli · 2002 · The Prostate
  105. Transplanting Normal Vascular Proangiogenic Cells to Tumor-Bearing Mice Triggers Vascular Remodeling and Reduces Hypoxia in Tumors
    Junpei Sasajima, Yusuke Mizukami, Yoshiaki Sugiyama, Kazumasa Nakamura, Toru Kawamoto, Kazuya Koizumi, Rie Fujii, Wataru Motomura, Kazuya Sato, Yasuaki Suzuki et al. · 2010 · Cancer Research
  106. Contrast enhanced MRI and intravital fluorescence microscopy indicate improved tumor microcirculation in highly vascularized melanomas upon short-term anti-VEGFR treatment
    Martin Eichhorn, Sebastian Strieth, Siiri Luedemann, Axel Kleespies, Ulrike Nöth, Alexander Passon, Gunnar Brix, K.‐W. Jauch, Christiane J. Bruns, Marc Dellian · 2008 · Cancer Biology & Therapy
  107. TSU68, an antiangiogenic receptor tyrosine kinase inhibitor, induces tumor vascular normalization in a human cancer xenograft nude mouse model
    Manabu Ohta, Toshiki Kawabata, Masayoshi Yamamoto · 2009 · Surgery Today
  108. Oxygen Sensing: A Common Crossroad in Cancer and Neurodegeneration
    Annelies Quaegebeur, Peter Carmeliet · 2010 · Current topics in microbiology and immunology
  109. Microvascular abnormalities in patients with rheumatoid arthritis
    Giuseppe Alessandro Scardina, Pietro Messina · 2006 · Annals of Anatomy - Anatomischer Anzeiger
  110. Taming Glioblastoma by Targeting Angiogenesis: 3 Years Later
    Eric T. Wong, Steven S. Brem · 2010 · Journal of Clinical Oncology
  111. Tumor growth in organ culture.
    Moses Judah Folkman, Long Dm, Becker Ff · 1962 · PubMed
  112. MAb 806 Enhances the Efficacy of Ionizing Radiation in Glioma Xenografts Expressing the de2-7 Epidermal Growth Factor Receptor
    Terrance G. Johns, Michael Jerome McKay, Anna N. Cvrljevic, Hui Kong Gan, Caitlin Taylor, Huiling Xu, Fiona E. Smyth, Andrew Mark Scott · 2010 · International Journal of Radiation Oncology*Biology*Physics
  113. Abnormal oral vascular network geometric complexity in Ehlers-Danlos syndrome
    Claudio De Felice, Giorgio Bianciardi, L Dileo · 2004 · Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology
  114. Post-transcriptional Control Regulates Transforming Growth Factor α in the Human Carcinoma KB Cell Line
    Gabriella Nicolini, Mariarosaria Miloso, Maria Cristina Moroni, Laura Beguinot, Luigi Scotto · 1996 · Journal of Biological Chemistry
  115. Interferon β–mediated vessel stabilization improves delivery and efficacy of systemically administered topotecan in a murine neuroblastoma model
    Paxton Vandiver Dickson, Nikolaus L. Hagedorn, John Blair Hamner · 2007 · Journal of Pediatric Surgery
  116. Alterations in the vascular architecture of the dorsal root ganglia in a rat neuropathic pain model
    Luboš Kubíček, Roman Kopáčik, Ilona Klusáková, Petr Dubový · 2010 · Annals of Anatomy - Anatomischer Anzeiger
  117. Induction of thrombospondin-1 partially mediates the anti-angiogenic activity of dexrazoxane
    Stephanie Louise Maloney, D C Sullivan, Steven Suchting, John M. J. Herbert, Erzsebet M. Rabai, Zsuzsanna Nagy, Juliet N. Barker, Sudha S. Sundar, Roy Bicknell · 2009 · British Journal of Cancer
  118. MRI Assessment of Angiogenesis Inhibitor Sunitinib's Influence on Tumor Oxygenation to Identify an Optimal Chemoradiotherapeutic Window
    S. Batra, Shingo Matsumoto, Fuminori Hyodo, J. Mitchell, Murali Cherukuri Krishna · 2009 · International Journal of Radiation Oncology*Biology*Physics
  119. Pharmacokinetics (PK) of pegylated liposomal doxorubicin (PLD) given alone and with bevacizumab (B) in patients with recurrent epithelial ovarian cancer (rEOC).
    Franco M. Muggia, Tamar Safra, Lucia Borgato · 2010 · Journal of Clinical Oncology
  120. Multiple brain infarcts after orbital inflammation.
    Katie Luneau, Bonnie Bruce, Nancy J Newman · 2009 · PubMed