Renal Autoregulation in Health and Disease

Carlström, Mattias, Wilcox, Christopher S., Arendshorst, William J.·2015·Physiological Reviews

DOI 10.1152/physrev.00042.2012

Cites (1,700)

Items 1,001–1,200 of 1,701

Modification of myogenic intrinsic tone and [Ca2+]i of rat isolated arterioles by ryanodine and cyclopiazonic acid.
Jun Watanabe, Akihiko Karibe, Satoru Horiguchi, Mitsumasa Keitoku, S. Satoh, Tamotsu Takishima, Kazuya Shirato · 1993 · Circulation Research
Adenosine A2Areceptor activation attenuates tubuloglomerular feedback responses by stimulation of endothelial nitric oxide synthase
Mattias Carlström, Christopher Stuart Wilcox, William J. Welch · 2010 · American Journal of Physiology-Renal Physiology
Effects of inhibition of the Na+/K+/2Cl− cotransporter on myogenic and angiotensin II responses of the rat afferent arteriole
Xuemei Wang, Jennifer Breaks, Kathy Loutzenhiser, Rodger Loutzenhiser · 2006 · American Journal of Physiology-Renal Physiology
Effects of insulin on rat renal microvessels: Studies in the isolated perfused hydronephrotic kidney
Kôichi Hayashi, Keiji Fujiwara, Kiyoshi Oka, Takahiko Nagahama, Hiroto Matsuda, Takao Saruta · 1997 · Kidney International
ENaC Regulation by Proteases and Shear Stress
Shujie Shi, Marcelo D. Carattino, Rebecca P. Hughey, Thomas R. Kleyman · 2013 · Current Molecular Pharmacology
Renal Functional Reserve in the Early Stage of Experimental Diabetes
Luca De Nicola, Roland C. Blantz, Francis B. Gabbai · 1992 · Diabetes
P2X1receptor blockade inhibits whole kidney autoregulation of renal blood flow in vivo
David A. Osmond, Edward W. Inscho · 2010 · American Journal of Physiology-Renal Physiology
NO dependency of RBF and autoregulation in the spontaneously hypertensive rat
Simona Racasan, Jaap A. Joles, Peter de Boer, Hein A. Koomans, Branko G. Braam · 2003 · American Journal of Physiology-Renal Physiology
Nitric Oxide Dependency of Arterial Pressure–Induced Changes in Renal Interstitial Hydrostatic Pressure in Dogs
Dewan S. A. Majid, Karim E. Said, Sophia A. Omoro, Luis Gabriel Navar · 2001 · Circulation Research
Transfer of the CYP4A region of chromosome 5 from Lewis to Dahl S rats attenuates renal injury
Jan Michael Williams, Albert Sarkis, Kimberly M. Hoagland, Katherine M. Fredrich, Robert P. Ryan, Carol Moreno, Bernardo López, Jozef Lazar, Francisco J. Fenoy, Mukut Sharma et al. · 2008 · American Journal of Physiology-Renal Physiology
Renal Interstitial Guanosine Cyclic 3′, 5′-Monophosphate Mediates Pressure-Natriuresis Via Protein Kinase G
Xiaohong Jin, Helen E. McGrath, John J Gildea, Helmy M. Siragy, Robin Allen Felder, Robert M. Carey · 2004 · Hypertension
Cellular and ionic signal transduction mechanisms for the mechanical activation of renal arterial vascular smooth muscle.
R. J. Roman, David Rae Harder · 1993 · Journal of the American Society of Nephrology
Impaired Ca 2+ Signaling Attenuates P2X Receptor–Mediated Vasoconstriction of Afferent Arterioles in Angiotensin II Hypertension
Xueying Zhao, Anthony K. Cook, Mary B. Field, Brentan Edwards, Shali Zhang, Zhanying Zhang, Jennifer S. Pollock, John D. Imig, Edward W. Inscho · 2005 · Hypertension
Inhibition of prostaglandin E2 secretion. Failure to abolish autoregulation in the isolated dog kidney.
George J. Kaloyanides, R E Ahrens, J A Shepherd, Gerald F. DiBona · 1976 · Circulation Research
Influence of pressure alterations on tone and vasomotion of isolated mesenteric small arteries of the rat.
Ed VanBavel, Maurice J.M.M. Giezeman, Trudi Mooij, Jos A. E. Spaan · 1991 · The Journal of Physiology
Onset of glomerular hypertension with aging precedes injury in the spontaneously hypertensive rat
Evelyn M. Tolbert, Joseph Weisstuch, Helen D. Feiner, Lance D. Dworkin · 2000 · American Journal of Physiology-Renal Physiology
Effects of DuP 753 on Renal Function of Normotensive and Spontaneously Hypertensive Rats
Francisco J. Fenoy, Ivan Milicic, Ronald D. Smith, Pancras C. Wong, Pieter B.M.W.M. Timmermans, Richard J. Roman · 1991 · American Journal of Hypertension
Signal transduction in spontaneous myogenic tone in isolated arterioles from rat skeletal muscle
Erik N.T.P. Bakker · 1999 · Cardiovascular Research
Afferent arteriolar responsiveness to altered perfusion pressure in renal hypertension.
Edward W. Inscho, Pamela K. Carmines, Anthony K. Cook, Luis Gabriel Navar · 1990 · Hypertension
Glomerular hemodynamics in moderate Goldblatt hypertension in the rat.
Robert W. Steiner, Bryan J. Tucker, Leslie C. Gushwa, J Gifford, Curtis B. Wilson, Roland C. Blantz · 1982 · Hypertension
Intrinsic control of sodium excretion in the distal nephron by inhibitory purinergic regulation of the epithelial Na+ channel
Glenn M. Toney, Volker Vallon, James D. Stockand · 2011 · Current Opinion in Nephrology & Hypertension
Direct Role for Smooth Muscle Cell Mineralocorticoid Receptors in Vascular Remodeling: Novel Mechanisms and Clinical Implications
Jenny B. Koenig, Iris Zamir Jaffe · 2014 · Current Hypertension Reports
Transport and Function of Chloride in Vascular Smooth Muscles
Vladimir V. Matchkov, Vibeke Secher Dam, Donna Briggs Boedtkjer, Christian Aalkjær · 2012 · Journal of Vascular Research
Dietary salt enhances benzamil-sensitive component of myogenic constriction in mesenteric arteries
Nikki L. Jernigan, Babette LaMarca, Josh Speed, Lauren Galmiche, Joey P. Granger, Heather A. Drummond · 2007 · American Journal of Physiology-Heart and Circulatory Physiology
Ryanodine receptor and capacitative Ca2+ entry in fresh preglomerular vascular smooth muscle cells
Susan K. Fellner, William J. Arendshorst · 2000 · Kidney International
Spontaneously hypertensive rat resistance artery structure related to myogenic and mechanical properties
Stuart J. Bund · 2001 · Clinical Science
Upregulation of juxtaglomerular NOS1 and COX-2 precedes glomerulosclerosis in fawn-hooded hypertensive rats
Wilko Weichert, Alexander Paliege, Abraham P. Provoost, Sebastian Bachmann · 2001 · American Journal of Physiology-Renal Physiology
Impaired myogenic constriction of the renal afferent arteriole in a mouse model of reduced βENaC expression
Ying Chun Ge, Kimberly P. Gannon, Monette Gousset, Ruishing Liu, Beau Murphey, Heather A. Drummond · 2012 · American Journal of Physiology-Renal Physiology
Effects of the antioxidant drug tempol on renal oxygenation in mice with reduced renal mass
En Yin Lai, Zaiming Luo, Maristela Lika Onozato, Earl H. Rudolph, Glenn Solis, Pedro A. José, Anton Wellstein, Shakil Aslam, Mark T. Quinn, Kathy K. Griendling et al. · 2012 · American Journal of Physiology-Renal Physiology
The Effect of Superoxide Anion on Autoregulation of Cerebral Blood Flow
Drazen Zagorac, Ken Yamaura, Cindy Zhang, Richard J. Roman, David Rae Harder · 2005 · Stroke
DEVELOPMENT OF HYPERTENSION AND PROTEINURIA WITH AGE IN FAWN‐HOODED RATS
M. H. M. Kuijpers, Abraham P. Provoost, Wybren de Jong · 1986 · Clinical and Experimental Pharmacology and Physiology
Architecture of inner medullary descending and ascending vasa recta: pathways for countercurrent exchange
Justin Yuan, Thomas Lloyd Pannabecker · 2010 · American Journal of Physiology-Renal Physiology
Isolation of a Chromosome 1 Region That Contributes to High Blood Pressure and Salt Sensitivity
Naoharu Iwai, Yasuyuki Tsujita, Masahiko Kinoshita · 1998 · Hypertension
Renal microvascular actions of calcitonin gene-related peptide
Martina Reslerova, Rodger Loutzenhiser · 1998 · American Journal of Physiology-Renal Physiology
Effect of renal decapsulation on renal interstitial hydrostatic pressure and natriuresis
Ali A. Khraibi, Franklyn G. Knox · 1989 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
Autoregulation of intravascular pressure in preglomerular juxtamedullary vessels
Daniel Casellas, L. C. Moore · 1993 · American Journal of Physiology-Renal Physiology
Role of angiotensin in the renal vasoconstriction observed during the development of genetic hypertension.
William J. Arendshorst, Christos Chatziantoniou, Fred. H. Daniels · 1990 · PubMed
Inflammatory Lesions in the Glomeruli in Pyelonephritis in Relation to Hypertension and Renal Insufficiency.
Paul Kimmelstiel, Clifford Wilson · 1936 · PubMed
Micropuncture studies on the dog kidney
Gerhart Liebau, David Z. Levine, Klaus Thurau · 1968 · Pflügers Archiv - European Journal of Physiology
Local Regulation of Microvascular Perfusion
Michael John Davis, Michael A. Hill, Lih Kuo · 2008 · Comprehensive physiology
Mechanisms underlying regional differences in the Ca2+sensitivity of BKCacurrent in arteriolar smooth muscle
Yan Yang, Yoshiro Sohma, Zahra Nourian, Srikanth R. Ella, Min Li, Aaron J. Stupica, Ronald J. Korthuis, Michael John Davis, Andrew P. Braun, Michael A. Hill · 2013 · The Journal of Physiology
Diabetes and microvascular pathophysiology: role of epidermal growth factor receptor tyrosine kinase
Khalid Matrougui · 2009 · Diabetes/Metabolism Research and Reviews
Nonspecific Inhibition of Myogenic Tone by PD98059, a MEK1 Inhibitor, in Rat Middle Cerebral Arteries
Guy Lagaud, Eugene K. Lam, Amy Lui, Cornelis van Breemen, Ismail Laher · 1999 · Biochemical and Biophysical Research Communications
Role of phospholipase C in development of myogenic tone in rat posterior cerebral arteries
Yagna P. R. Jarajapu, Harm Johan Knot · 2002 · American Journal of Physiology-Heart and Circulatory Physiology
The step response: a method to characterize mechanisms of renal blood flow autoregulation
T. Wronski, Erdmann Seeliger, Pontus Börje Persson, C. Vázquez Forner, C. Fichtner, J. Scheller, Bert Flemming · 2003 · American Journal of Physiology-Renal Physiology
Cerebral artery responses to pressure and flow in uremic hypertensive and spontaneously hypertensive rats
David I. New, A. M. S. Chesser, Raj C. Thuraisingham, Muhammad Magdi Yaqoob · 2003 · American Journal of Physiology-Heart and Circulatory Physiology
Renal protective effects of N-acetyl-Ser-Asp-Lys-Pro in deoxycorticosterone acetate–salt hypertensive mice
Nour‐Eddine Rhaleb, Saraswati Pokharel, Umesh C. Sharma, Oscar A. Carretero · 2010 · Journal of Hypertension
Multiple factors contribute to acetylcholine-induced renal afferent arteriolar vasodilation during myogenic and norepinephrine- and KCl-induced vasoconstriction. Studies in the isolated perfused hydronephrotic kidney.
Kôichi Hayashi, Rodger Loutzenhiser, Murray Epstein, Hidenori Suzuki, Takao Saruta · 1994 · Circulation Research
NOX2 is the primary source of angiotensin II-induced superoxide in the macula densa
Yiling Fu, Rui Zhang, Deyin Lu, Haifeng Liu, Kiran Chandrashekar, Luis Augusto Juncos, Ruisheng Liu · 2010 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
Role of 20-HETE in the impaired myogenic and TGF responses of the Af-Art of Dahl salt-sensitive rats
Ying Chun Ge, Sydney Murphy, Fan Fan, Jan Michael Williams, John Russell Falck, Ruisheng Liu, Richard J. Roman · 2014 · American Journal of Physiology-Renal Physiology
ANG II signaling in vasa recta pericytes by PKC and reactive oxygen species
Zhong Zhang, Kristie Rhinehart, Whaseon Lee Kwon, Edward J. Weinman, Thomas L. Pallone · 2004 · American Journal of Physiology-Heart and Circulatory Physiology
Central and Regional Hemodynamics and Plasma Volume Distribution During the Development of Spontaneous Hypertension in Rats
R. T. Evenwel, Carina M. Kasbergen, Harry A. J. Struyker-Boudier · 1983 · Clinical and Experimental Hypertension
Autoregulation of renal medullary blood flow in rabbits
Gabriela A. Eppel, Göran M.L. Bergström, Warwick P. Anderson, Roger G. Evans · 2003 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
Tonic and phasic influences of nitric oxide on renal blood flow autoregulation in conscious dogs
Armin Just, Heimo Ehmke, Uwe Wittmann, Hartmut R. Kirchheim · 1999 · American Journal of Physiology-Renal Physiology
Gender differences in myogenic tone in superoxide dismutase knockout mouse: animal model of oxidative stress
Sukrutha Veerareddy, Christy‐Lynn M. Cooke, Philip Newton Baker, Sandra Thomas Davidge · 2004 · American Journal of Physiology-Heart and Circulatory Physiology
Mechanisms for Renal Blood Flow Control Early in Diabetes as Revealed by Chronic Flow Measurement and Transfer Function Analysis
Tracy D. Bell, Gerald F. DiBona, Ying Wang, Michael W. Brands · 2006 · Journal of the American Society of Nephrology
Spontaneous glomerulosclerosis: insights from the fawn-hooded rat.
A. P. Provoost · 1994 · PubMed
Effects of a calcium entry blocker on blood pressure and renal function during angiotensin-induced hypertension.
Jan L. Huelsemann, Ralf Bernd Sterzel, Douglass E. McKenzie, Christopher Stuart Wilcox · 1985 · Hypertension
Systolic blood pressure as the trigger for the renal myogenic response: protective or autoregulatory?
Rodger Loutzenhiser, Karen A. Griffin, ANIL K. BIDANI · 2005 · Current Opinion in Nephrology & Hypertension
Renal Blood Flow Dynamics and Arterial Pressure Lability in the Conscious Rat
Silene L. S. Pires, Christian Barrès, Jean Sassard, Claude Julien · 2001 · Hypertension
Impaired renal autoregulatory ability in dogs with reduced renal mass.
Scott Anthony Brown, Delmar R. Finco, Luis Gabriel Navar · 1995 · Journal of the American Society of Nephrology
Increased arterial smooth muscle Ca2+ signaling, vasoconstriction, and myogenic reactivity in Milan hypertensive rats
Cristina I. Linde, Eiji Karashima, Hema Raina, Alessandra Zulian, Withrow Gil Wier, John M. Hamlyn, Patrizia Ferrari, Mordecai P. Blaustein, Vera A. Golovina · 2011 · American Journal of Physiology-Heart and Circulatory Physiology
P2 receptor-mediated afferent arteriolar vasoconstriction during calcium blockade
Edward W. Inscho, Anthony K. Cook · 2002 · American Journal of Physiology-Renal Physiology
Enhanced renal vasoconstriction induced by vasopressin in SHR is mediated by V1 receptors
J. J. Feng, William J. Arendshorst · 1996 · American Journal of Physiology-Renal Physiology
Interactions of cAMP-mediated vasodilators with angiotensin II in rat kidney during hypertension
Christos Chatziantoniou, Xiaoping Ruan, William J. Arendshorst · 1993 · American Journal of Physiology-Renal Physiology
Role of cytochromeP-450 metabolites in the regulation of renal function and blood pressure in 2-kidney 1-clip hypertensive rats
Alexandra Sporková, Libor Kopkan, Šárka Jíchová, Zuzana Husková, Sung Hee Hwang, Bruce D. Hammock, John D. Imig, Herbert J. Kramer, Luděk Červenka · 2011 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
Localization of inositol 1,4,5-trisphosphate receptors in the rat kidney
Toshiaki Monkawa, Matsuhiko Hayashi, Atsushi Miyawaki, Tomoyasu Sugiyama, Miki Yamamoto‐Hino, Mamoru Hasegawa, Teiichi Furuichi, Katsuhiko Mikoshiba, Takao Saruta · 1998 · Kidney International
Molecular Mechanisms and Therapeutic Strategies of Chronic Renal Injury: Role of Rho-Kinase in the Development of Renal Injury
Kôichi Hayashi, Shu Wakino, Takeshi Kanda, Koichiro Homma, Naoki Sugano, Takao Saruta · 2006 · Journal of Pharmacological Sciences
Enalapril and renal injury in spontaneously hypertensive rats.
L G Feld, Steven Cachero, Judith B. Van Liew, Marianna J. Zamlauski-Tucker, B Noble · 1990 · Hypertension
Renal microvascular actions of angiotensin II fragments
William F. van Rodijnen, Ton A. van Lambalgen, Michiel H. van Wijhe, Geert Jan Tangelder, Piet M. ter Wee · 2002 · American Journal of Physiology-Renal Physiology
Cortical and medullary hemodynamics in deoxycorticosterone acetate-salt hypertensive mice.
V Groß, Andrea Lippoldt, Jörg Edgar Bohlender, Michael Bäder, Astrid Fritz Hansson, Friedrich Cameron Luft · 1998 · Journal of the American Society of Nephrology
Integrin mobilizes intracellular Ca2+ in renal vascular smooth muscle cells
Wah-Lun Chan, Niels‐Henrik Holstein‐Rathlou, Kay‐Pong Yip · 2001 · American Journal of Physiology-Cell Physiology
Effects of antihypertensive drugs on autoregulation of RBF and glomerular capillary pressure in SHR
Fred Ivan Kvam, Jarle Ofstad, Bjarne M. Iversen · 1998 · American Journal of Physiology-Renal Physiology
Frequency domain analysis of renal autoregulation in the rat
Tenei Sakai, E. Hallman, Donald J. Marsh · 1986 · American Journal of Physiology-Renal Physiology
In-vivo studies of new vector velocity and adaptive spectral estimators in medical ultrasound.
Kristoffer Lindskov Hansen · 2010 · PubMed
Development of renal lesions in dogs after 11/12 reduction of renal mass. Influences of dietary protein intake.
David J. Polzin, Joel R. Leininger, Cari A. Osborne, Karim Jeraj · 1988 · PubMed
Decreased activity of the smooth muscle Na+/Ca2+ exchanger impairs arteriolar myogenic reactivity
Hema Raina, Srikanth R. Ella, Michael A. Hill · 2008 · The Journal of Physiology
Dietary Protein Intake and the Glomerular Adaptations to Partial Nephrectomy in Dogs
Scott A. Brown, Delmar R. Finco, Wayne A. Crowell, Luis Gabriel Navar · 1991 · Journal of Nutrition
Ca2+entry following P2X receptor activation induces IP3receptor‐mediated Ca2+release in myocytes from small renal arteries
Oleksandr V. Povstyan, Maksym I. Harhun, Dmitri V. Gordienko · 2010 · British Journal of Pharmacology
Pressure-independent cerebrovascular remodelling and changes in myogenic reactivity in diabetic Goto-Kakizaki rat in response to glycaemic control
Aisha I. Kelly-Cobbs, Mostafa M. Elgebaly, W. Li, Adviye Ergul · 2010 · Acta Physiologica
The Afferent Glomerular Arteriole
Ch. Ph. Bührle, Rainer Nobiling, E. Mannek, D. Schneider, E. Hackenthal, Roland Taugner · 1984 · Journal of Cardiovascular Pharmacology
Endothelin: Role in Experimental Hypertension
Ernesto L. Schiffrin · 2000 · Journal of Cardiovascular Pharmacology
Restoration of Connexin 40 (Cx40) in Renin-Producing Cells Reduces the Hypertension of Cx40 Null Mice
Loïc Le Gal, Florian Alonso, Charlotte Wagner, Stéphane Germain, Denise Nardelli‐Haefliger, Paolo Meda, Jacques‐Antoine Haefliger · 2014 · Hypertension
An update on cyclooxygenase-2 expression and metabolites in the kidney
Raymond Clement Harris · 2008 · Current Opinion in Nephrology & Hypertension
Identification of a QTL on chromosome 1 for impaired autoregulation of RBF in fawn-hooded hypertensive rats
Bernardo López, Robert P. Ryan, Carol Moreno, Albert Sarkis, Jozef Lazar, Abraham P. Provoost, Howard J. Jacob, Richard J. Roman · 2005 · American Journal of Physiology-Renal Physiology
Cyclic GMP‐dependent and cyclic GMP‐independent actions of nitric oxide on the renal afferent arteriole
Greg Trottier, Chris R. Triggle, Sean K. O'Neill, Rodger Loutzenhiser · 1998 · British Journal of Pharmacology
Glomerular filtration during furosemide diuresis in the dog
Thomas J. Burke, Kenneth L. Duchin · 1979 · Kidney International
Control of rat glomerular microcirculation by juxtaglomerular adenosine A1 receptors
Masahiko Kawabata, Tetsuya Ogawa, Toshikazu Takabatake · 1998 · Kidney International
The epithelial Na+ channel
Kristina Kusche‐Vihrog, Antoine Tarjus, Johannes Fels, Frédéric Jaisser · 2013 · Current Opinion in Nephrology & Hypertension
Increased genetic susceptibility to renal damage in the stroke-prone spontaneously hypertensive rat
Paul C. Churchill, Monique C. Churchill, Karen A. Griffin, Maria Mrozowicz Picken, Robert Clinton Webb, Theodore W. Kurtz, ANIL K. BIDANI · 2002 · Kidney International
Pressure Natriuresis in Nitric Oxide-Deficient Hypertensive Rats
Lourdes A. Fortepiani, Elena Rodrigo, M. Clara Ortíz, Victoria Cachofeiro, Noemí M. Atuchá, Luis Miguel Ruilope, Vicente Lahera, Joaquín García‐Estañ · 1999 · Journal of the American Society of Nephrology
Micropuncture Analysis of Tubuloglomerular Feedback Regulation in Transgenic Mice
Jurgen B. Schnermann · 1999 · Journal of the American Society of Nephrology
Natriuretic Response to Increased Pressure Is Preserved With COX-2 Inhibitors
Jennifer M. Gross, Jennifer E. Dwyer, Franklyn G. Knox · 1999 · Hypertension
Divergent Mechanisms of ATP-Sensitive K + Channel–Induced Vasodilation in Renal Afferent and Efferent Arterioles
Martina Reslerova, Rodger Loutzenhiser · 1995 · Circulation Research
Role of angiotensin II in dynamic renal blood flow autoregulation of the conscious dog
Armin Just, Heimo Ehmke, Uwe Wittmann, Hartmut R. Kirchheim · 2002 · The Journal of Physiology
Increased shear stress–released NO and decreased endothelial calcium in rat isolated perfused juxtamedullary nephrons
János Pittner, MATS WOLGAST, Daniel Casellas, A. Erik G. Persson · 2004 · Kidney International
Impaired ability of prostaglandins to buffer renal vasoconstriction in genetically hypertensive rats
Christos Chatziantoniou, William J. Arendshorst · 1992 · American Journal of Physiology-Renal Physiology
Patterns in autoregulation of renal blood flow in the dog
C. F. Röthe, F.D. Nash, DE Thompson · 1971 · American Journal of Physiology-Legacy Content
Differences in dynamic autoregulation of renal blood flow between SHR and WKY rats
Y. M. Chen, Niels‐Henrik Holstein‐Rathlou · 1993 · American Journal of Physiology-Renal Physiology
Purinoreceptor‐mediated current in myocytes from renal resistance arteries
Maksym I. Harhun, Oleksandr V. Povstyan, Dmitri V. Gordienko · 2010 · British Journal of Pharmacology
Angiotensin II/prostaglandin I2 interactions in spontaneously hypertensive rats.
Edwin Kerry Jackson, William A. Herzer · 1993 · Hypertension
Pregnancy prevents hypertensive remodeling and decreases myogenic reactivity in posterior cerebral arteries from Dahl salt-sensitive rats: a role in eclampsia?
Annet M. Aukes, Lisa Vitullo, Gerda G. Zeeman, Marilyn J. Cipolla · 2006 · American Journal of Physiology-Heart and Circulatory Physiology
Renin release from isolated afferent arterioles
Sadayoshi Ito, Oscar A. Carretero, Robert Douglas Murray · 1985 · Kidney International
Endogenously produced 20-HETE modulates myogenic and TGF response in microperfused afferent arterioles
Ying Chun Ge, Sydney Murphy, Yan Lü, John Russell Falck, Ruisheng Liu, Richard J. Roman · 2013 · Prostaglandins & Other Lipid Mediators
BLOOD PRESSURE AND LIFESPAN FOLLOWING BRIEF ACE INHIBITOR TREATMENT IN YOUNG SPONTANEOUSLY HYPERTENSIVE RATS
Stephen B. Harrap, Christine Mirakian, Shari R. Datodi, Anthony F. Lever · 1994 · Clinical and Experimental Pharmacology and Physiology
Nitric oxide, atrial natriuretic factor, and dynamic renal autoregulation
Xuemei Wang, Fred C. Salevsky, William A. Cupples · 1999 · Canadian Journal of Physiology and Pharmacology
Local electric stimulation causes conducted calcium response in rat interlobular arteries
Max Salomonsson, Finn Gustafsson, Ditte Andreasen, Boye Lagerbon Jensen, Niels‐Henrik Holstein‐Rathlou · 2002 · American Journal of Physiology-Renal Physiology
Nitric oxide release as an essential mitigating step in tubuloglomerular feedback
Erika Turkstra, Branko Braam, H A Koomans · 1998 · Journal of the American Society of Nephrology
Contrasting Effects of Selective T- and L-Type Calcium Channel Blockade on Glomerular Damage in DOCA Hypertensive Rats
Habib Karam, Jean‐Paul Clozel, Patrick Bruneval, Marie-Françoise Gonzalez, Joël Ménard · 1999 · Hypertension
Signalling mechanisms underlying the myogenic response in human subcutaneous resistance arteries
Paul Coats · 2001 · Cardiovascular Research
Pentosan Polysulfate Prevents Glomerular Hypertension and Structural Injury Despite Persisting Hypertension in 5/6 Nephrectomy Rats
Norma Araceli Bobadilla, Ivan Tack, Edilia Tapia, Laura Gabriela Sánchez‐Lozada, José Santamaría, Fabiola Jiménez, Liliane J. Striker, Gary E. Striker, Jaime Herrera-Acosta · 2001 · Journal of the American Society of Nephrology
Oscillations and chaos in renal blood flow control.
Niels‐Henrik Holstein‐Rathlou · 1993 · Journal of the American Society of Nephrology
Potassium channel contributions to afferent arteriolar tone in normal and diabetic rat kidney
Carmen M. Troncoso Brindeiro, Rachel W. Fallet, Pascale Hammond Lane, Pamela K. Carmines · 2008 · American Journal of Physiology-Renal Physiology
Complex interactions of NO/cGMP/PKG systems on Ca2+signaling in afferent arteriolar vascular smooth muscle
Susan K. Fellner, William J. Arendshorst · 2009 · American Journal of Physiology-Heart and Circulatory Physiology
Functional Importance of L- and P/Q-Type Voltage-Gated Calcium Channels in Human Renal Vasculature
Pernille Hansen, Christian Bjørn Poulsen, Steen Walter, Niels Marcussen, Leanne L. Cribbs, Ole Skøtt, Boye Lagerbon Jensen · 2011 · Hypertension
Brief losartan treatment in young spontaneously hypertensive rats abates long-term blood pressure elevation by effects on renal vascular structure
Göran M.L. Bergström, Inger Johansson, Anna Wickman, Li‐Ming Gan, Christian Thorup · 2002 · Journal of Hypertension
Exaggerated tubuloglomerular feedback activity in genetic hypertension is mediated by ANG II and AT1 receptors
Kristina Brännström, Peter Morsing, William J. Arendshorst · 1996 · American Journal of Physiology-Renal Physiology
Renal interstitial pressure and sodium excretion during hilar lymphatic ligation
Christopher Stuart Wilcox, Ralf Bernd Sterzel, Phyllis T. Dunckel, M. Mohrmann, M. C. Perfetto · 1984 · American Journal of Physiology-Renal Physiology
Reversal of renal and smooth muscle actions of the thromboxane mimetic U-44069 by diltiazem
Rodger Loutzenhiser, Murray Epstein, Charles Horton, P. Sonke · 1986 · American Journal of Physiology-Renal Physiology
Angiotensin II conditions the slow component of autoregulation of renal blood flow
W. A. Cupples · 1993 · American Journal of Physiology-Renal Physiology
Evaluation of prostaglandins as mediators of tubuloglomerular feedback
Martha Franco, Phillip Darwin Bell, Luis Gabriel Navar · 1988 · American Journal of Physiology-Renal Physiology
Diseases of the kidney & urinary tract
Robert W. Schrier · 2007 · Medical Entomology and Zoology
Vascular reactivity to angiotensin II is selectively enhanced in the kidneys of spontaneously hypertensive rats.
Curtis K. Kost, William A. Herzer, Peng Li, Edwin Kerry Jackson · 1994 · Journal of Pharmacology and Experimental Therapeutics
Nonstationarity and 1/f noise characteristics in heart rate
Berndt Pilgram, Daniel T. Kaplan · 1999 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
The Effects of Poststroke Captopril and Losartan Treatment on Cerebral Blood Flow Autoregulation in SHRsp with Hemorrhagic Stroke
John Stanislaw Smeda, Noriko Daneshtalab · 2010 · Journal of Cerebral Blood Flow & Metabolism
Severe hypertension induces disturbances of renal autoregulation.
Jerusa Almeida, M A Saragoça, Aline Cristina Tavares, Mário Luís Ribeiro Cesaretti, Sérgio Antônio Draibe, O L Ramos · 1992 · Hypertension
Role of prostaglandins in proximal tubule sodium reabsorption: response to elevated renal interstitial hydrostatic pressure.
Y. Kinoshita, Franklyn G. Knox · 1989 · Circulation Research
Rho-kinase inhibition reduces pressure-mediated autoregulatory adjustments in afferent arteriolar diameter
Edward W. Inscho, Anthony K. Cook, Robert Clinton Webb, Li-Ming Jin · 2009 · American Journal of Physiology-Renal Physiology
Renin, Angiotensin, Sodium and Organ Damage
Trefor Owen Morgan · 2003 · Hypertension Research
Capillary Reperfusion after L-Arginine, L-NMMA, and L-NNA Treatment in Cheek Pouch Microvasculature
Silvia Bertuglia, A. Colantuoni, Marcos Intaglietta · 1995 · Microvascular Research
Afferent arteriolopathy and glomerular collapse but not segmental sclerosis induce tubular atrophy in old spontaneously hypertensive rats
Sabine Maria Leh, Michael Hultström, Christian Rosenberger, Bjarne M. Iversen · 2011 · Archiv für Pathologische Anatomie und Physiologie und für Klinische Medicin
Coexpression of Voltage-Dependent Calcium Channels Cav1.2, 2.1a, and 2.1b in Vascular Myocytes
Ditte Andreasen, Ulla Glenert Friis, Torben R. Uhrenholt, Boye Lagerbon Jensen, Ole Skøtt, Pernille Hansen · 2006 · Hypertension
Role of Endothelium-derived Hyperpolarizing Factor in Phenylephrine-induced Oscillatory Vasomotion in Rat Small Mesenteric Artery
Kayoko Okazaki, Sumihiko Seki, Noriaki Kanaya, Jun-ichi Hattori, Noritsugu Tohse, Akiyoshi Namiki · 2003 · Anesthesiology
Myogenic Responses of Mouse Isolated Perfused Renal Afferent Arterioles
En Yin Lai, Maristela Lika Onozato, Glenn Solis, Shakil Aslam, William J. Welch, Christopher Stuart Wilcox · 2010 · Hypertension
Genetic Analysis of Rat Chromosome 1 and the Sa Gene in Spontaneous Hypertension
Elizabeth St. Lezin, Weizhong Liu, Jiaming Wang, Ying Yang, Nianning Qi, Vladimír Křen, Václav Zı́dek, Theodore W. Kurtz, Michal Pravenec · 2000 · Hypertension
Epithelial Na+ channel proteins are mechanotransducers of myogenic constriction in rat posterior cerebral arteries
Eok‐Cheon Kim, Duck‐Sun Ahn, Soo‐In Yeon, Mihwa Lim, Young‐Ho Lee · 2011 · Experimental Physiology
Genetic basis of the impaired renal myogenic response in FHH rats
Marilyn F. Burke, Malikarjuna R. Pabbidi, Fan Fan, Ying Chun Ge, Ruisheng Liu, Jan Michael Williams, Allison B. Sarkis, Jozef Lazar, Howard J. Jacob, Richard J. Roman · 2012 · American Journal of Physiology-Renal Physiology
Absence of estimated glomerular pressure autoregulation during interrupted distal delivery
L. Gabriel Navar, Bungorn Chomdej, Phillip Darwin Bell · 1975 · American Journal of Physiology-Legacy Content
Long-term hypotensive effects of an angiotensin converting enzyme inhibitor in spontaneously hypertensive rats: is there a role for vascular structure?
Christensen Hr, H K Nielsen, K L Christensen, Ulrik Thorngren Baandrup, Lennard Tang Jespersen, Michael John Mulvany · 1988 · PubMed
Synergistic Intrarenal Actions of Angiotensin on Tubular Reabsorption and Renal Hemodynamics
Luis Gabriel Navar, Gaetano Saccomani, Kenneth D. Mitchell · 1991 · American Journal of Hypertension
Coordinated Regulation of Vascular Ca2+ and K+ Channels by Integrin Signaling
Peichun Gui, Jun-Tzu Chao, Xin Yi Wu, Yan Yang, George E. Davis, Michael John Davis · 2010 · Advances in experimental medicine and biology
Elevated arterial pressure impairs autoregulation independently of AT1 receptor activation
Edward W. Inscho, Anthony K. Cook, James B. Murzynowski, John D. Imig · 2004 · Journal of Hypertension
Mechanism of impaired afferent arteriole myogenic response in Dahl salt-sensitive rats: role of 20-HETE
YiLin Ren, Martin A. D’Ambrosio, Jeffrey Lawrence Garvin, Edward L. Peterson, Oscar A. Carretero · 2014 · American Journal of Physiology-Renal Physiology
PI3K in hypertension: a novel therapeutic target controlling vascular myogenic tone and target organ damage
Daniela Carnevale, Giuseppe Lembo · 2012 · Cardiovascular Research
Impaired resistance artery function in patients with end-stage renal disease
Natallia Luksha, Leanid Luksha, Juan Jesús Carrero, Folke Hammarqvist, Peter Stenvinkel, Karolina R. Kublickiene · 2011 · Clinical Science
Role of nNOS in Regulation of Renal Function in Angiotensin II–Induced Hypertension
Luděk Červenka, Herbert J. Kramer, Jan Malý, Jiří Heller · 2001 · Hypertension
Alterations in Renal Medullary Hemodynamics and the Pressure-Natriuretic Response in Genetic Hypertension
R. J. Roman · 1990 · American Journal of Hypertension
The Na‐K‐ATPase is a target for an EDHF displaying characteristics similar to potassium ions in the porcine renal interlobar artery
Eckhart Büssemaker, Christian Wallner, Beate Fißlthaler, Ingrid Fleming · 2002 · British Journal of Pharmacology
Diversity and variability of smooth muscle phenotypes of renal arterioles as revealed by myosin isoform expression
Kenjiro Kimura, Ryozo Nagai, Tatsuo Sakai, Masanori Aikawa, Makoto Kuro-o, Naoto Kobayashi, Isao Shirato, Tadashi Inagami, Masaya Oshi, Naoe Suzuki et al. · 1995 · Kidney International
Autoregulation and non‐homeostatic behaviour of renal blood flow in conscious dogs.
Pontus Börje Persson, Heimo Ehmke, Hartmut R. Kirchheim, B Janssen, J E Baumann, Armin Just, Benno Nafz · 1993 · The Journal of Physiology
Myogenic Tone in Coronary Arteries from Spontaneously Hypertensive Rats
Susana R. Garcia, Ashley S. Izzard, Anthony Michael Heagerty, Stuart J. Bund · 2008 · Journal of Vascular Research
Possible Mediators of Connecting Tubule Glomerular Feedback
Yilin Ren, Martin A. D’Ambrosio, Jeffrey Lawrence Garvin, Hong Wang, Oscar A. Carretero · 2008 · Hypertension
ADP-ribosyl cyclase and ryanodine receptor activity contribute to basal renal vasomotor tone and agonist-induced renal vasoconstriction in vivo
Tiffany L. Thai, Susan K. Fellner, William J. Arendshorst · 2007 · American Journal of Physiology-Renal Physiology
Soluble epoxide hydrolase-dependent regulation of myogenic response and blood pressure
Dong Sun, Azita J. Cuevas, Katherine H. Gotlinger, Sung Hee Hwang, Bruce D. Hammock, Michal Laniado Schwartzman, An Huang · 2014 · American Journal of Physiology-Heart and Circulatory Physiology
SOD1 deficiency causes salt sensitivity and aggravates hypertension in hydronephrosis
Mattias Carlström, Russell D. Brown, Johan Sällström, Erik Larsson, Mihkel Zilmer, Sheller Zabihi, Ulf J. Eriksson, A. Erik G. Persson · 2009 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
20-HETE Contributes to Myogenic Activation of Skeletal Muscle Resistance Arteries in Brown Norway and Sprague–Dawley Rats
Jefferson C. Frisbee, Richard J. Roman, John Russell Falck, U. Murali Krishna, Julian H. Lombard · 2001 · Microcirculation
Alterations in Autoregulatory and Myogenic Function in the Cerebrovasculature of Dahl Salt-Sensitive Rats
John Stanislaw Smeda, Geoffrey W. Payne · 2003 · Stroke
Cerebral vascular autoregulation of blood flow and tissue PO2 in diabetic rats
Michael J. Rubin, H. Glenn Bohlen · 1985 · American Journal of Physiology-Heart and Circulatory Physiology
Morphometric evaluation of the renal arterial system of Dahl salt-sensitive and salt-resistant rats on a high salt diet. II. Interlobular arteries and intralobular arterioles.
J A Hampton, D A Bernardo, Najam Ali Khan, D A Lacher, John P. Rapp, A F Gohara, Goldblatt Pj · 1989 · PubMed
Effect of interactions between nitric oxide and angiotensin II on pressure diuresis and natriuresis
Marı́a Isabel Madrid, Miguel Garcı́a-Salom, Jerónimo Tornel, Marc de Gasparo, Francisco J. Fenoy · 1997 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
ANGIOTENSIN AND RENAL VASCULAR DAMAGE.
Byrom Fb · 1964 · PubMed
Evidence for tubuloglomerular feedback in juxtamedullary nephrons of young rats
Roland Müller-Suur, Hans R. Ulfendahl, A. Erik G. Persson · 1983 · American Journal of Physiology-Renal Physiology
Restoration of vasa recta hemodynamics and pressure natriuresis in SHR by L-arginine
T. S. Larson, J. C. Lockhart · 1995 · American Journal of Physiology-Renal Physiology
Effect of increases in blood pressure on pressure and reabsorption in the proximal tubule
TP Dresser, RE Lynch, EG Schneider, FG Knox · 1971 · American Journal of Physiology-Legacy Content
COX-2-specific inhibitors and the kidney: effect on hypertension and oedema.
Jaime Herrera-Acosta, Edilia Tapia, Laura G Sánchez-Lozada, Martha Franco, Liliane J Striker, Gary E Striker, Iturbe Bernardo Rodríguez · 2002 · PubMed
Clinical and pathological course of renal disease in non-insulin-dependent diabetes mellitus: the Pima Indian experience.
Robert G. Nelson, Timothy W. Meyer, Bryan D. Myers, P H Bennett · 1997 · PubMed
Differential effects of salt on renal hemodynamics and potential pressure transmission in stroke-prone and stroke-resistant spontaneously hypertensive rats
Isam Abu‐Amarah, ANIL K. BIDANI, Rıfat Hacıoğlu, Geoffrey A. Williamson, Karen A. Griffin · 2005 · American Journal of Physiology-Renal Physiology
Tubuloglomerular feedback and prolonged ACE-inhibitor treatment in the hypertensive fawn-hooded rat
Gaico H. Verseput, Branko G. Braam, A. P. Provoost, Hein A. Koomans · 1998 · Nephrology Dialysis Transplantation
Adenosine A2 receptors modulate tubuloglomerular feedback
Mattias Carlström, Christopher Stuart Wilcox, William J. Welch · 2010 · American Journal of Physiology-Renal Physiology
NO, via its target Cx37, modulates calcium signal propagation selectively at myoendothelial gap junctions
Kristin Pogoda, Monika Füller, Ulrich Pohl, Petra Kameritsch · 2014 · Cell Communication and Signaling
Renal vascular dysfunction precedes the development of renal damage in the hypertensive Fawn-Hooded rat
Peter Ochodnický, Robert H. Henning, Hendrik Buikema, Dick de Zeeuw, Abraham P. Provoost, Richard P.E. van Dokkum · 2009 · American Journal of Physiology-Renal Physiology
Role of Connexin37 and Connexin40 in Vascular Development
Alexander M. Simon, Andrea R. McWhorter · 2003 · Cell Communication & Adhesion
Modification of pressure natriuresis by long-term losartan in spontaneously hypertensive rats.
Robert L. Kline, F Liu · 1994 · Hypertension
Effect of renal perfusion pressure on renal interstitial hydrostatic pressure in rats
Ali A. Khraibi, John A. Haas, Franklyn G. Knox · 1989 · American Journal of Physiology-Renal Physiology
Diverse effects of calcium antagonists on glomerular hemodynamics.
Shuji Arima, Sadayoshi Ito, Ken Omata, Kazuo Tsunoda, Hiraku Yaoita, Abe K · 1996 · PubMed
Role of renal interstitial hydrostatic pressure in natriuresis of systemic nitric oxide inhibition
John A. Haas, Ali A. Khraibi, Mark A. Perrella, Franklyn G. Knox · 1993 · American Journal of Physiology-Renal Physiology
Beneficial Effect of Nifedipine and Moxonidine on Glomerulosclerosis in Spontaneously Hypertensive Rats
Tomasz Jerzy Irzyniec, Gerhard Mall, Doris Greber, Eberhard Ritz · 1992 · American Journal of Hypertension
Angiotensin II and renal functional reserve in rats with Goldblatt hypertension.
Luca De Nicola, Joan A. Keiser, Roland C. Blantz, Francis B. Gabbai · 1992 · Hypertension
Telmisartan improves endothelial dysfunction and renal autoregulation in Dahl salt-sensitive rats
Minoru Satoh, Yoshisuke Haruna, Sohachi Fujimoto, Tamaki Sasaki, Naoki Kashihara · 2009 · Hypertension Research
Calcium Dynamics and Vasomotion in Arteries Subject to Isometric, Isobaric, and Isotonic Conditions
Michèle Koenigsberger, Roger Sauser, Dominique Seppey, Jean‐Louis Bény, Jean-Jacques Meister · 2008 · Biophysical Journal
Hypertension increases middle cerebral artery resting tone in spontaneously hypertensive rats: role of tonic vasoactive factor availability
José María González, Beatriz Somoza, M.V. Conde, María S. Fernández‐Alfonso, M. Carmen González, Silvia Magdalena Arribas · 2008 · Clinical Science
Voltage-gated Ca2+entry and ryanodine receptor Ca2+-induced Ca2+release in preglomerular arterioles
Susan K. Fellner, William J. Arendshorst · 2006 · American Journal of Physiology-Renal Physiology
Glomerular and renal hemodynamics during converting enzyme inhibition (SQ20,881) in the dog.
Luis Gabriel Navar, Ronald Lagrange, Phillip Darwin Bell, Charles E. Thomas, David W. Ploth · 1979 · Hypertension
Intracellular Acidification Alters Myogenic Responsiveness and Vasomotion of Mouse Middle Cerebral Arteries
Axel BK Thomsen, Sukhan Kim, Filip Aalbaek, Christian Aalkjær, Ebbe Boedtkjer · 2013 · Journal of Cerebral Blood Flow & Metabolism
Tubuloglomerular feedback mechanisms in nephron segments beyond the macula densa
Péter Komlósi, Phillip Darwin Bell, Zhi‐Ren Zhang · 2008 · Current Opinion in Nephrology & Hypertension
Calcium and chloride channel activation by angiotensin II-AT1receptors in preglomerular vascular smooth muscle cells
Andrew J. Fuller, Benjamin C. Hauschild, Romer A. González-Villalobos, Mouhamed S. Awayda, John D. Imig, Edward W. Inscho, Luis Gabriel Navar · 2005 · American Journal of Physiology-Renal Physiology
Long-term renal changes in the Goto-Kakizaki rat, a model of lean type 2 diabetes
Bieke F. Schrijvers, An S. De Vriese, Johan Van de Voorde, Ruth Rasch, Norbert Hendrik Lameire, Allan Flyvbjerg · 2004 · Nephrology Dialysis Transplantation
Membrane current oscillations in descending vasa recta pericytes
Qingli Zhang, Chunhua Cao, Zhong Zhang, W. Gil Wier, Aurélie Edwards, Thomas L. Pallone · 2008 · American Journal of Physiology-Renal Physiology
Tubuloglomerular feedback and renin secretion in NTPDase1/CD39-deficient mice
Mona Oppermann, David J. Friedman, Robert Faulhaber‐Walter, Diane E. Mizel, Hayo Castrop, Keiichi Enjyoji, Simon Christopher Robson, Jurgen B. Schnermann · 2008 · American Journal of Physiology-Renal Physiology
NAADP receptors mediate calcium signaling stimulated by endothelin-1 and norepinephrine in renal afferent arterioles
Tiffany L. Thai, Grant C. Churchill, William J. Arendshorst · 2009 · American Journal of Physiology-Renal Physiology
Regulation of ecto-5′-nucleotidase by NaCl and nitric oxide: potential roles in tubuloglomerular feedback and adaptation
Joseph A. Satriano, Lucinda M. Wead, Ana Cardus Figueras, Aihua Deng, Gerry R. Boss, Scott Culver Thomson, Roland C. Blantz · 2006 · American Journal of Physiology-Renal Physiology
Nitric oxide, superoxide and renal blood flow autoregulation in SHR after perinatal L ‐arginine and antioxidants
Maarten P. Koeners, Simona Racasan, Hein A. Koomans, Jaap A. Joles, Branko G. Braam · 2007 · Acta Physiologica
Vasopressin modulation of medullary blood flow and pressure-natriuresis-diuresis in the decerebrated rat
Kleber Gomes Franchini, David L. Mattson, A. W. Cowley · 1997 · American Journal of Physiology-Regulatory, Integrative and Comparative Physiology
Do TRPC-like currents and G protein-coupled receptors interact to facilitate myogenic tone development?
Yana Anfinogenova, Suzanne E. Brett, Michael P. Walsh, Osama F. Harraz, Donald Gordon Welsh · 2011 · American Journal of Physiology-Heart and Circulatory Physiology
Insights into angiotensin II receptor function through AT2 receptor knockout mice
V Groß, Michael Obst, Friedrich Cameron Luft · 2004 · Acta Physiologica Scandinavica
Cyclooxygenase inhibition potentiates myogenic activity in skeletal muscle arterioles
Michael A. Hill, Michael John Davis, G. A. Meininger · 1990 · American Journal of Physiology-Heart and Circulatory Physiology
Sex differences in control of renal outer medullary circulation in rats: role of prostaglandins
N. Parekh, A. P. Zou, I. Jungling, Karlhans Endlich, Janusz Sadowski, M. Steinhausen · 1993 · American Journal of Physiology-Renal Physiology
Role of guanylyl cyclase and cytochromeP-450 on renal response to nitric oxide
Bernardo López Andrade, Carol Moreno, Miguel G. Salom, Richard J. Roman, Francisco J. Fenoy · 2001 · American Journal of Physiology-Renal Physiology
Detection of interactions between myogenic and TGF mechanisms using nonlinear analysis
Ki H. Chon, Y. M. Chen, Vasilis Z. Marmarelis, Donald J. Marsh, Niels‐Henrik Holstein‐Rathlou · 1994 · American Journal of Physiology-Renal Physiology
Reactive Oxygen Species and RhoA Signaling in Vascular Smooth Muscle: Role in Chronic Hypoxia-Induced Pulmonary Hypertension
Thomas C. Resta, Brad R. S. Broughton, Nikki L. Jernigan · 2009 · Advances in experimental medicine and biology