Molecular physiology of bile acid signaling in health, disease, and aging

Cites (485)

Items 401–486 of 486

1. Treatment with the natural FXR agonist chenodeoxycholic acid reduces clearance of plasma LDL whilst decreasing circulating PCSK 9, lipoprotein(a) and apolipoprotein C‐ III
   Moumita Ghosh Laskar, Mats Eriksson, Mats J. Rudling, Bo Angelin · 2017 · Journal of Internal Medicine
2. Therapeutic modulation of the bile acid pool by Cyp8b1 knockdown protects against nonalcoholic fatty liver disease in mice
   Raphaël Chèvre, Laia Trigueros‐Motos, David Castaño, Tricia Chua, Maria Corlianò, Jay V. Patankar, Lareina Sng, Lauren Sim, Tan Liang Juin, Guillaume Carissimo et al. · 2018 · The FASEB Journal
3. Low-fat, high-carbohydrate and high-fat, low-carbohydrate diets decrease primary bile acid synthesis in humans
   Peter H L T Bisschop, Robert Bandsma, Frans Stellaard, Anke ter Harmsel, Alfred J. Meijer, Hans P. Sauerwein, Folkert Kuipers, Johannes Anthonius Romijn · 2004 · American Journal of Clinical Nutrition
4. β‐Catenin regulation of farnesoid X receptor signaling and bile acid metabolism during murine cholestasis
   Michael David Thompson, Akshata Moghe, Pamela K. Cornuet, Rebecca B. Marino, Jianmin Tian, Pengcheng Wang, Xiaochao Ma, Marc T. Abrams, Joseph D. Locker, Satdarshan P. Monga et al. · 2017 · Hepatology
5. Bile Acid Flux Is Necessary for Normal Liver Regeneration
   Naugler, Willscott E. · 2014 · PLoS ONE
6. Taurodeoxycholate activates potassium and chloride conductances via an IP3-mediated release of calcium from intracellular stores in a colonic cell line (T84)
   Daniel C. Devor, M C Sekar, R. A. Frizzell, Michael E. Duffey · 1993 · Journal of Clinical Investigation
7. Complex interaction between circadian rhythm and diet on bile acid homeostasis in male rats
   Hannah M. Eggink, Johanneke E. Oosterman, Paul de Goede, Emmely M. de Vries, Ewout Foppen, Martijn Koehorst, Albert Kornelis Groen, Anita Boelen, Johannes Anthonius Romijn, Susanne Eva la Fleur et al. · 2017 · Chronobiology International
8. Deficiency of Both Farnesoid X Receptor and Takeda G Protein–Coupled Receptor 5 Exacerbated Liver Fibrosis in Mice
   Ferrell, Jessica M., Pathak, Preeti, Boehme, Shannon, Gilliland, Tricia, Chiang, John Y. L. · 2019 · Hepatology
9. The Farnesoid X Receptor: Good for BAD
   Stephen J. Keely, Julian R.F. Walters · 2016 · Cellular and Molecular Gastroenterology and Hepatology
10. Simultaneous inhibition of FXR and TGR5 exacerbates atherosclerotic formation
    Shinobu Miyazaki‐Anzai, Masashi Masuda, Shohei Kohno, Moshe Levi, Yuji Shiozaki, Audrey L. Keenan, Makoto Miyazaki · 2018 · Journal of Lipid Research
11. FGF19 Analog as a Surgical Factor Mimetic That Contributes to Metabolic Effects Beyond Glucose Homeostasis
    Alex M. DePaoli, Mei Zhou, Daniel D. Kaplan, Steven C. Hunt, Ted D. Adams, R. Marc Learned, Hui Tian, Lei Ling · 2019 · Diabetes
12. TGR5 agonist ameliorates insulin resistance in skeletal muscles and improves glucose homeostasis in diabetic mice
    Suling Huang, Shan-yao Ma, Mengmeng Ning, Wenji Yang, Yangliang Ye, Lina Zhang, Jianhua Shen, Ying Leng · 2019 · Metabolism
13. Farnesoid X Receptor Activation Attenuates Intestinal Ischemia Reperfusion Injury in Rats
    Laurens Joseph Ceulemans, Len Verbeke, Jean-Paul Decuypere, Ricard Farré, Gert D. Hertogh, Kaatje Lenaerts, Ina Jochmans, Diethard R.L. Monbaliu, Frederik Nevens, Jan F. Tack et al. · 2017 · PLoS ONE
14. Topical Intestinal Aminoimidazole Agonists of G-Protein-Coupled Bile Acid Receptor 1 Promote Glucagon Like Peptide-1 Secretion and Improve Glucose Tolerance
    Manuel Lasalle, Vanessa Hoguet, Nathalie Hennuyer, Florence Leroux, Catherine Piveteau, Loïc Belloy, Sophie Lestavel, Emmanuelle Vallez, Emilie Dorchies, Isabelle Duplan et al. · 2017 · Journal of Medicinal Chemistry
15. Mechanistic insights into the detection of free fatty and bile acids by ileal glucagon-like peptide-1 secreting cells
    Deborah A. Goldspink, Van B. Lu, Lawrence Billing, Pierre Larraufie, Gwen Tolhurst, Fiona Mary Gribble, Frank M. Reimann · 2017 · Molecular Metabolism
16. Obeticholic acid may increase the risk of gallstone formation in susceptible patients
    Samer Al-Dury, Annika M. Wahlstrom, Katrin Panzitt, Anders Thorell, Marcus Ståhlman, Michael A Trauner, Peter Fickert, Fredrik Bäckhed, Lars Fändriks, Martin Wagner et al. · 2019 · Journal of Hepatology
17. Modulation of rat hepatocyte proliferation by bile salts: In vitro and In vivo studies
    M. Barone · 1996 · Hepatology
18. Effect of Jaundice on Rheumatoid Arthritis
    Philip S. Hench · 1938 · BMJ
19. Farnesoid X receptor protects liver cells from apoptosis induced by serum deprivation in vitro and fasting in vivo.
    Yan-Dong Wang, Fan Yang, Wei-Dong Chen, Xiong-Fei Huang, L. Lai, B. M. Forman, Wen-Dong Huang · 2008 · Molecular Endocrinology
20. Characterization of chenodeoxycholic acid as an endogenous antagonist of the G-coupled formyl peptide receptors
    Xin Chen, De Yang, Weiping Shen, Hui Dong, J M Wang, Joost J. Oppenheim, O. M. Zack Howard · 2000 · Inflammation Research
21. Farnesoid X receptor agonist INT-767 attenuates liver steatosis and inflammation in rat model of nonalcoholic steatohepatitis
    Yingbin Hu, Xinyu Liu, Wei Zhan · 2018 · Drug Design Development and Therapy
22. Functional interaction of lithocholic acid conjugates with M3 muscarinic receptors on a human colon cancer cell line
    Kunrong Cheng, Ying Chen, Piotr Zimniak, Jean‐Pierre Raufman, Yinghua Xiao, Harold Frucht · 2002 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
23. Bile Acids Decrease Hepatic Paraoxonase 1 Expression and Plasma High-Density Lipoprotein Levels Via FXR-Mediated Signaling of FGFR4
    Alejandra Gutierrez, Eric P. Ratliff, Allen M. Andres, Xinqiang Huang, Wallace L. McKeehan, Roger A. Davis · 2005 · Arteriosclerosis Thrombosis and Vascular Biology
24. Gq and Gs signaling acting in synergy to control GLP-1 secretion
    Maria Hauge, Jeppe H. Ekberg, Maja Storm Engelstoft, Pascal N. Timshel, Andreas Nygaard Madsen, Thue Walter Schwartz · 2016 · Molecular and Cellular Endocrinology
25. RNA-binding protein ZFP36L1 maintains posttranscriptional regulation of bile acid metabolism
    Elizabeth J. Tarling, Bethan L. Clifford, Joan Cheng, Pauline Morand, Angela Cheng, Ellen Lester, Tamer Sallam, Martin Turner, Thomas Q. de Aguiar Vallim · 2017 · Journal of Clinical Investigation
26. Glucocorticoid receptor mediates the gluconeogenic activity of the farnesoid X receptor in the fasting condition
    Barbara Renga, Andrea Mencarelli, Claudio D’Amore, Sabrina Cipriani, Franco Baldelli, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci · 2012 · The FASEB Journal
27. Molecular magnetic resonance imaging accurately measures the antifibrotic effect of EDP‐305, a novel farnesoid X receptor agonist
    Derek J. Erstad, Christian T. Farrar, Sarani Ghoshal, Ricard Masia, Diêgo S. Ferreira, Yin‐Ching Iris Chen, Ji‐Kyung Choi, Lan Wei, Phillip A. Waghorn, Nicholas Joseph Rotile et al. · 2018 · Hepatology Communications
28. Relationship between three commonly used non‐invasive fibrosis biomarkers and improvement in fibrosis stage in patients with non‐alcoholic steatohepatitis
    Naga Chalasani, Manal F. Abdelmalek, Rohit Seth Loomba, Kris V. Kowdley, Arthur J. McCullough, Srinivasan Dasarathy, Brent A. Neuschwander‐Tetri, Norah A. Terrault, Beatrice Ferguson, Reshma Shringarpure et al. · 2018 · Liver International
29. β-Klotho deficiency protects against obesity through a crosstalk between liver, microbiota, and brown adipose tissue
    Emmanuel Somm, Hugues Henry, Stephen J. Bruce, Sébastien Aeby, Marta Rosikiewicz, Gerasimos P. Sykiotis, Mohammed Asrih, François R. Jornayvaz, Pierre‐Damien Denechaud, Urs Albrecht et al. · 2017 · JCI Insight
30. The bile acid receptor, TGR 5, regulates basal and cholinergic‐induced secretory responses in rat colon
    Joseph B. J. Ward, Magdalena Slawa Mroz, Stephen J. Keely · 2013 · Neurogastroenterology & Motility
31. Sterol transporter adenosine triphosphate-binding cassette transporter G8, gallstones, and biliary cancer in 62,000 individuals from the general population
    Stefan Stender, Ruth Frikke‐Schmidt, Børge Grønne Nordestgaard, Anne Tybjærg‐Hansen · 2010 · Hepatology
32. Gpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice
    Adriana Carino, Sabrina Cipriani, Silvia Marchianò, Michele Biagioli, Paolo Tommaso Scarpelli, Angela Zampella, Maria Chiara Monti, Stefano Fiorucci · 2017 · Scientific Reports
33. Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis
    Adriana Carino, Silvia Marchianò, Michele Biagioli, Mariarosaria Bucci, Valentina Vellecco, Vincenzo Brancaleone, Chiara Fiorucci, Angela Zampella, Maria Chiara Monti, Eleonora Distrutti et al. · 2018 · The FASEB Journal
34. Farnesoid X Receptor Expression Is Decreased in Colonic Mucosa of Patients with Primary Sclerosing Cholangitis and Colitis-associated Neoplasia
    Joana Torres, Xiuliang Bao, Alina Cornelia Iuga, Anli Chen, Noam Harpaz, Thomas A. Ullman, Benjamin L. Cohen, Guillaume Pineton de Chambrun, Stefania Asciutti, Joseph A. Odin et al. · 2013 · Inflammatory Bowel Diseases
35. Direct methylation of FXR by Set7/9, a lysine methyltransferase, regulates the expression of FXR target genes
    Natarajan Balasubramaniyan, Meenakshisundaram Ananthanarayanan, Frederick J. Suchy · 2012 · American Journal of Physiology-Gastrointestinal and Liver Physiology
36. Bile Acid-induced Epidermal Growth Factor Receptor Activation in Quiescent Rat Hepatic Stellate Cells Can Trigger Both Proliferation and Apoptosis
    Annika Sommerfeld, Roland Reinehr, Dieter Häussinger · 2009 · Journal of Biological Chemistry
37. Bile acid receptor agonists INT747 and INT777 decrease oestrogen deficiency-related postmenopausal obesity and hepatic steatosis in mice
    Monique Cristine de Oliveira, Eduardo Hideo Gilglioni, Bouke A. de Boer, Jurgen Henk Runge, Dirk Rudi de Waart, Clairce Luzia Salgueiro, Emy Luiza Ishii‐Iwamoto, Ronald P.J. Oude Elferink, Ingrid C. Gaemers · 2016 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
38. Mechanisms to Elevate Endogenous GLP-1 Beyond Injectable GLP-1 Analogs and Metabolic Surgery
    Daniel A. Briere, Ana Belen Bueno, Ellen J. Gunn, M. Dodson Michael, Kyle W. Sloop · 2017 · Diabetes
39. Constitutive androstane receptor activation stimulates faecal bile acid excretion and reverse cholesterol transport in mice
    Anne-Laure Sberna, Mahfoud Assem, Thomas Gautier, Jacques Grober, Boris Guiu, Aline Jeannin, Jean-Paul Paı̈s de Barros, Anne Athias, Laurent Lagrost, David Masson · 2010 · Journal of Hepatology
40. Modeling and Experimental Studies of Obeticholic Acid Exposure and the Impact of Cirrhosis Stage
    JE Edwards, Carl LaCerte, Thomas Peyret, NH Gosselin, Jean‐Francois Marier, Hofmann Af, D Shapiro · 2016 · Clinical and Translational Science
41. Metabolite-Sensing G Protein Coupled Receptor TGR5 Protects Host From Viral Infection Through Amplifying Type I Interferon Responses
    Qingqing Xiong, Hongjun Huang, Ning Wang, Ruoyu Chen, Naiyang Chen, Honghui Han, Qin Wang, Stefan K. Siwko, Mingyao Liu, Min Qian et al. · 2018 · Frontiers in Immunology
42. Non-alcoholic fatty liver disease is associated with dysregulated bile acid synthesis and diarrhea: A prospective observational study
    Richard Appleby, Iman Moghul, Shahid Ahmed Khan, Michael S. Yee, Pinelopi Manousou, Tracy Dew Neal, Julian R.F. Walters · 2019 · PLoS ONE
43. Quantitative profiling of bile acids in rat bile using ultrahigh-performance liquid chromatography–orbitrap mass spectrometry: Alteration of the bile acid composition with aging
    Gakyung Lee, Hyunbeom Lee, Jongki Hong, Soo Hyun Lee, Byung Hwa Jung · 2016 · Journal of Chromatography B
44. Ursodeoxycholic acid enriches intestinal bile salt hydrolase-expressing Bacteroidetes in cholestatic pregnancy
    Caroline Ovadia, Álvaro Perdones-Montero, Hei Man Fan, Benjamin Harvey Mullish, Julie A. K. McDonald, Georgia Papacleovoulou, Annika M. Wahlstrom, Marcus Ståhlman, Anastasia Tsakmaki, Louise C. D. Clarke et al. · 2020 · Scientific Reports
45. A role for FXR and human FGF-19 in the repression of paraoxonase-1 gene expression by bile acids
    Diana M. Shih, Heidi R. Kast-Woelbern, Jack Wong, Yu-Rong Xia, Peter A. Edwards, Aldons Jake Lusis · 2005 · Journal of Lipid Research
46. Antagonism of sphingosine 1-phosphate receptor 2 causes a selective reduction of portal vein pressure in bile duct-ligated rodents
    Yuko Kageyama, Hitoshi Ikeda, Naoko Watanabe, Masakazu Nagamine, Yoshika Kusumoto, Mitsuru Yashiro, Yumiko Satoh, Tatsuo Shimosawa, Koji Shinozaki, Tomoaki Tomiya et al. · 2012 · Hepatology
47. Small heterodimer partner deletion prevents hepatic steatosis and when combined with farnesoid X receptor loss protects against type 2 diabetes in mice
    Oludemilade Akinrotimi, Ryan Riessen, Philip VanDuyne, Jung Eun Park, Yoon‐Kwang Lee, Lee‐Jun Wong, Ann Marie Zavacki, Kristina Schoonjans, Sayeepriyadarshini Anakk · 2017 · Hepatology
48. Lack of intestinal bile results in delayed liver regeneration of normal rat liver after hepatectomy accompanied by impaired cyclin E–associated kinase activity
    Junji Ueda, Kazuo Chijiiwa, Kenji Nakano, Gang Zhao, Masao Tanaka · 2002 · Surgery
49. Farnesoid X receptor activation increases cholesteryl ester transfer protein expression in humans and transgenic mice
    Thomas Gautier, Willeke de Haan, Jacques Grober, Dan Ye, Matthias J. Bahr, Thierry Claudel, Niels Nijstad, Theo J.C. van Berkel, Louis M. Havekes, Michael Peter Manns et al. · 2013 · Journal of Lipid Research
50. G Protein–Coupled Bile Acid Receptor 1 Stimulation Mediates Arterial Vasodilation through a KCa1.1 (BKCa)–Dependent Mechanism
    Ryan M. Fryer, Khing Jow Ng, Suzanne Nodop Mazurek, Lori A. Patnaude, Donna J. Skow, Akalushi C. Muthukumarana, Kyle E. Gilpin, Roger M. Dinallo, Daniel Kuzmich, John Lord et al. · 2014 · Journal of Pharmacology and Experimental Therapeutics
51. Mitochondrial membrane lipidome defines yeast longevity
    Adam Beach, Vincent R. Richard, Anna Leonov, Michelle T. Burstein, Simon D. Bourque, Olivia Koupaki, Mylène Juneau, Rachel Feldman, Tatiana L. Iouk, Vladimir I. Titorenko · 2013 · Aging
52. Takeda G Protein-Coupled Receptor 5-Mechanistic Target of Rapamycin Complex 1 Signaling Contributes to the Increment of Glucagon-Like Peptide-1 Production after Roux-en-Y Gastric Bypass
    Hening Zhai, Zhi Li, Miao Peng, Zhaoqi Huang, Tingfeng Qin, Linxi Chen, Hanbing Li, Heng Zhang, Weizhen Zhang, Geyang Xu · 2018 · EBioMedicine
53. Farnesoid X Receptor Induces Murine Scavenger Receptor Class B Type I via Intron Binding
    Guodong Li, Ann Thomas, Jessica A. R. Williams, Bo Kong, Jie Liu, Yuka Inaba, Wen Xie, Grace Liejun Guo · 2012 · PLoS ONE
54. Activation of farnesoid X receptor (FXR) protects against fructose-induced liver steatosis via inflammatory inhibition and ADRP reduction
    Xijun Liu, Ruyi Xue, Lingling Ji, Xingwang Zhang, Jian Huang Wu, Jianxin Gu, Meiling Zhou, She Chen · 2014 · Biochemical and Biophysical Research Communications
55. Deoxycholyltaurine-induced vasodilation of rodent aorta is nitric oxide- and muscarinic M3 receptor-dependent
    Sandeep Khurana, Masahisa Yamada, Jürgen Wess, Richard H. Kennedy, Jean‐Pierre Raufman · 2005 · European Journal of Pharmacology
56. Bile salt inhibition of motility in the isolated perfused rabbit terminal ileum.
    David N. Armstrong, H K Krenz, Irvin Mark Modlin, Garth H. Ballantyne · 1993 · Gut
57. Effect of jejunal infusion of bile acids on small bowel transit and fasting jejunal motility in man.
    Roberto Penagini, J J Misiewicz, Peter Frost · 1988 · Gut
58. Bile acids destabilise HIF-1α and promote anti-tumour phenotypes in cancer cell models
    John P. Phelan, F. Jerry Reen, Niall Dunphy, Rosemary O’Connor, Fergal O’Gara · 2016 · BMC Cancer
59. Acidified bile acids enhance tumor progression and telomerase activity of gastric cancer in mice dependent on c‐Myc expression
    Xiaolong Wang, Lei Sun, Xi-Jing Wang, Huafeng Kang, Xiaobin Ma, Meng Wang, Shuai Lin, Meng Liu, Cong Dai, Zhijun Dai · 2017 · Cancer Medicine
60. Effect of deoxycholic acid on colonic motility in the rabbit
    William J. Snape, S. J. Shiff, Sheldon Cohen · 1980 · American Journal of Physiology-Gastrointestinal and Liver Physiology
61. Administration of tauroursodeoxycholic acid enhances osteogenic differentiation of bone marrow-derived mesenchymal stem cells and bone regeneration
    Byung-Hyun Cha, Moon-Joo Jung, Bo-Kyung Moon, Jin‐Su Kim, Yoon-Ji Ma, Yoshie Arai, Myungkyung Noh, Jung‐Youn Shin, Byung‐Soo Kim, Soo‐Hong Lee · 2015 · Bone
62. Regulatory effects of deoxycholic acid, a component of the anti-inflammatory traditional Chinese medicine Niuhuang, on human leukocyte response to chemoattractants
    Xin Chen, R. Daniel Mellon, Lu Yang, Huifang Dong, Joost J. Oppenheim, O. M. Zack Howard · 2002 · Biochemical Pharmacology
63. Role of FXR in β-Cells of Lean and Obese Mice
    Björn Schittenhelm, Rebecca Wagner, Verena Kähny, Andreas Peter, Peter Krippeit‐Drews, Martina Düfer, Gisela Drews · 2015 · Endocrinology
64. Physiological concentrations of bile acids down‐regulate agonist induced secretion in colonic epithelial cells
    Niamh Keating, Magdalena Slawa Mroz, Michael M. Scharl, Christine Marsh, Gail Ferguson, Alan Frederick Hofmann, Stephen J. Keely · 2009 · Journal of Cellular and Molecular Medicine
65. FXR overexpression alters adipose tissue architecture in mice and limits its storage capacity leading to metabolic derangements
    Tim van Zutphen, Johanna H. M. Stroeve, Jiufang Yang, Vincent W. Bloks, Angelika Jurdzinski, Han Roelofsen, Nicolette Huijkman, Theo H. van Dijk, Roel J. Vonk, Jan van Deursen et al. · 2019 · Journal of Lipid Research
66. A mitochondrially targeted compound delays aging in yeast through a mechanism linking mitochondrial membrane lipid metabolism to mitochondrial redox biology
    Michelle T. Burstein, Vladimir I. Titorenko · 2014 · Redox Biology
67. A translational view on the biliary lipid secretory network
    Giuseppe Lo Sasso, Michele Petruzzelli, Antonio Moschetta · 2007 · Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids
68. Taurolithocholic acid promotes intrahepatic cholangiocarcinoma cell growth via muscarinic acetylcholine receptor and EGFR/ERK1/2 signaling pathway
    Sumet Amonyingcharoen, Tawit Suriyo, Apinya Thiantanawat, Piyajit Watcharasit, Jutamaad Satayavivad · 2015 · International Journal of Oncology
69. The nuclear receptor FXR regulates hepatic transport and metabolism of glutamine and glutamate
    Barbara Renga, Andrea Mencarelli, Sabrina Cipriani, Claudio D’Amore, Angela Zampella, Maria Chiara Monti, Eleonora Distrutti, Stefano Fiorucci · 2011 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
70. Cholesterol metabolism and serum and biliary noncholesterol sterols in gallstone patients during simvastatin and ursodeoxycholic acid treatments†
    T.E. Miettinen, Tuula A. Kiviluoto, Matti Taavitsainen, Matti Vuoristo, Tatu A. Miettinen · 1998 · Hepatology
71. Roux-en-Y Gastric Bypass Surgery-Induced Weight Loss and Metabolic Improvements Are Similar in TGR5-Deficient and Wildtype Mice
    Hao Zheng, R. Leigh Townsend, Michael B. Mumphrey, Thomas W. Gettys, Sangho Yu, Heike Münzberg, Christopher D. Morrison, Hans‐Rudolf Berthoud · 2018 · Obesity Surgery
72. Mechanism of deoxycholic acid stimulation of the rabbit colon.
    S. J. Shiff, R. D. Soloway, William J. Snape · 1982 · Journal of Clinical Investigation
73. Farnesoid X Receptor Activation Protects Liver From Ischemia/Reperfusion Injury by Up‐Regulating Small Heterodimer Partner in Kupffer Cells
    Dan Jin, Tian-Fei Lu, Ming Ni, Han Wang, Jiang Zhang, C. Zhong, Chuan Shen, Jun-Feng Hao, R. Busuttil, J. Kupiec-Weglinski et al. · 2020 · Hepatology Communications
74. Ursodeoxycholic Acid Induces Death Receptor-mediated Apoptosis in Prostate Cancer Cells
    Won Sup Lee, Ji Hyun Jung, Radha Panchanathan, Jeong Won Yun, Dong Hoon Kim, Hye Jung Kim, Gon Sup Kim, Chung Ho Ryu, Sung Chul Shin, Soon‐Chan Hong et al. · 2017 · Journal of Cancer Prevention
75. Tauroursodeoxycholate Protects Rat Hepatocytes from Bile Acid-Induced Apoptosis via β1-Integrin- and Protein Kinase A-Dependent Mechanisms
    Annika Sommerfeld, Roland Reinehr, Dieter Häussinger · 2015 · Cellular Physiology and Biochemistry
76. Crosstalk between the hepatologist and the cardiologist: A future place for the lithocholic acid as a coronary atheroma risk factor?
    Henri Duboc, Hélène Aelion, Dominique P. Rainteau, Sylvie Rajca, Harry Sokol, Lydie Humbert, Dominique Farabos, Benoît Coffin, Simon Weber, Raphaël Porcher et al. · 2012 · Hepatology
77. GLP-2 receptor signaling controls circulating bile acid levels but not glucose homeostasis in Gcgr mice and is dispensable for the metabolic benefits ensuing after vertical sleeve gastrectomy
    Anita R. Patel, Bernardo Yusta, Dianne Matthews, Maureen J. Charron, Randy J. Seeley, Daniel J. Drucker · 2018 · Molecular Metabolism
78. Activation of the bile acid receptor GPBAR1 (TGR5) ameliorates interleukin-1β (IL-1β)- induced chondrocytes senescence
    He Huang, Hongwei Lei, Fan Yang, Xuemei Fan, Qiujie Dang, Li Yang · 2018 · Biomedicine & Pharmacotherapy
79. TGR5 Protects Against Colitis in Mice, but Vertical Sleeve Gastrectomy Increases Colitis Severity
    Darline Garibay, Karolina E. Zaborska, Michael T. Shanahan, Qiaonan Zheng, Katie M. Kelly, David C. Montrose, Andrew J. Dannenberg, Andrew David Miller, Praveen Sethupathy, Bethany P. Cummings · 2019 · Obesity Surgery
80. Bile acid detoxifying enzymes limit susceptibility to liver fibrosis in female SHRSP5/Dmcr rats fed with a high-fat-cholesterol diet
    Husna Yetti, Hisao Naito, Yuan Yuan, Xiaofang Jia, Yumi Hayashi, Hazuki Tamada, Kazuya Kitamori, Katsumi Ikeda, Yukio Yamori, Tamie Nakajima · 2018 · PLoS ONE
81. Bile acid supplementation decreases body mass gain in C57BL/6J but not 129S6/SvEvTac mice without increasing energy expenditure
    Tobias Fromme, Kristina Hüttinger, Stefanie Maurer, Yongguo Li, Thomas Gantert, Jarlei Fiamoncini, Hannelore Daniel, Sören Westphal, Martin Klingenspor · 2019 · Scientific Reports
82. Bile acid accelerates erbB2-induced pro-tumorigenic activities in biliary tract cancer
    Takuya Kitamura, Jaya Srivastava, John DiGiovanni, Kaoru Kiguchi · 2013 · Molecular Carcinogenesis
83. Missing link identified: GpBAR1 is a neuronal bile acid receptor
    Stephen J. Keely · 2010 · Neurogastroenterology & Motility
84. Effects of Bile Acids on Human Colonic Motor Function in vitro
    M. Flynn, P. Hammond, Christine Darby, I Taylor · 2009 · Digestion
85. Bile acids target proteolipid nano-assemblies of EGFR and phosphatidic acid in the plasma membrane for stimulation of MAPK signaling
    Liang Hong, Mary Kolb Estes, Huiling Zhang, Guangwei Du, Yong Zhou · 2018 · PLoS ONE
86. Some Effects of Salicylate on Plant Viruses
    Rupert Jethro Best · 1940 · Nature