The DOI matches its Crossref record.
Mechanism of the development of obesity in animals with hypothalamic lesions.
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In the citing paper
“brain centers in the hypothalamus receive peripheral signals that reflect an organism's nutritional state as part of a feedback loop or loops that maintain homeostatic control of body weight (14,15).”
From Leptin at 14 y of age: an ongoing story (2009) · cites this paper as [14]
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Sorted by citations
Positional cloning of the mouse obese gene and its human homologue
Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., & Friedman, J. M. (1994) · Nature · doi:10.1038/372425a0 · Cited by 13,419
Interacting Appetite-Regulating Pathways in the Hypothalamic Regulation of Body Weight
Kalra, S. P., Dube, M. G., Pu, S., Xu, B., Horváth, T. L., & Kalra, P. S. (1999) · Endocrine Reviews · doi:10.1210/edrv.20.1.0357 · Cited by 1,564
“These observations led Anand and Brobeck (24, 25) to conceptualize LH as a “feeding center” for elaboration of “urge to eat” normally restrained by signals from VMH.”
BackgroundHypothalamic control of food intake in rats and cats.
Anand, B. K., & Brobeck, J. R. (1951) · PubMed · Cited by 1,197
Self-citationLeptin and Obesity: Role and clinical implication.
Obradovic, M., Sudar-Milovanovic, E., Soskic, S., Essack, M., Arya, S., Stewart, A. J., Gojobori, T., & Isenovic, E. R. (2021) · Frontiers in Endocrinology · doi:10.3389/fendo.2021.585887 · Cited by 1,121
“Earlier studies revealed that lesions of the ARC, VMH, or DMH could lead to hyperphagia and obesity in rats (29, 30), and lesions of the LH can lead to anaphylaxis (31).”
BackgroundGadde (2018) · doi:10.1016/j.jacc.2017.11.011 · Cited by 626
Metadata
- Authors
- Brobeck, J. R.
- Corresponding author
- Brobeck, John R.
- Venue
- Physiological Reviews
- Publisher
- American Physiological Society
- Published
- 1946-10-01
- Volume
- 26
- Issue
- 4
- Pages
- 541-559
- ISSN
- 0031-9333 (ISSN-L)
- 1522-1210
- OpenAlex
- W2311863019
- Cited by
- 488
- References
- 0
- Citations by year
- 2026: 1 · 2025: 2 · 2024: 6 · 2023: 5 · 2022: 8 · 2021: 11 · 2020: 9 · 2019: 5 · 2018: 4 · 2017: 12 · 2016: 1 · 2015: 18 · 2014: 10 · 2013: 3 · 2012: 8
- FWCI
- 8.93
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Physiological Reviews (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
- Health Sciences › Medicine › Reproductive Medicine › Hypothalamic control of reproductive hormones
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
- Keywords
- obesity, hypothalamic lesions, hypothalamus, feeding behavior, energy homeostasis, animal models of obesity
- MeSH terms
- Animals, Hypothalamus, Obesity
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