Cells of bone: proliferation, differentiation, and hormonal regulation
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Osteoclasts develop from fused macrophages and are considered part of the mononuclear phagocyte system.
“As osteoclasts develop from fused macrophages, osteoclasts are considered to be a component of the mononuclear phagocyte system [257,258].”
From MicroRNAs as Regulators of Phagocytosis (2022) · cites this paper as [258]
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Osteoprotegerin: a novel secreted protein involved in the regulation of bone density.
Simonet, W. S., Lacey, D. L., Dunstan, C. R., Kelley, M., Chang, M.-S., Lüthy, R., Nguyen, H. Q., Wooden, S., Bennett, L., Boone, T., et al. (1997) · Cell · doi:10.1016/s0092-8674(00)80209-3 · Cited by 5,130 · see citing works
BELLOWS, C. G., AUBIN, J. E., & HEERSCHE, J. N. M. (1987) · Endocrinology · doi:10.1210/endo-121-6-1985 · Cited by 306 · see citing works
RANKL/OPG; Critical role in bone physiology
Martin, T. J., & Sims, N. A. (2015) · Reviews in Endocrine and Metabolic Disorders · doi:10.1007/s11154-014-9308-6 · Cited by 213 · see citing works
Athanasou, N. A., & Quinn, J. (1990) · Journal of Clinical Pathology · doi:10.1136/jcp.43.12.997 · Cited by 182 · see citing works
Death of osteocytes turns off the inhibition of osteoclasts and triggers local bone resorption
Gu, G., Mulari, M., Peng, Z., Hentunen, T. A., & Väänänen, H. K. (2005) · Biochemical and Biophysical Research Communications · doi:10.1016/j.bbrc.2005.06.211 · Cited by 123 · see citing works
Ikegame, M., Rakopoulos, M., Martin, T. J., Moseley, J. M., & Dr. Findlay, D. M. (1996) · Journal of Bone and Mineral Research · doi:10.1002/jbmr.5650110406 · Cited by 36 · see citing works
MicroRNAs as Regulators of Phagocytosis
Gierlikowski, W., & Gierlikowska, B. (2022) · Cells · doi:10.3390/cells11091380 · Cited by 25 · see citing works
Olufsen, M., & Arukwe, A. (2011) · Aquatic Toxicology · doi:10.1016/j.aquatox.2011.09.005 · Cited by 20 · see citing works
- Authors
- Nijweide, P. J., Burger, E. H., & Feyen, J. H.
- ORCID
- Feyen, J. H.
- Venue
- Physiological Reviews
- Publisher
- American Physiological Society
- Published
- 1986-10-01
- Volume
- 66
- Issue
- 4
- Pages
- 855-886
- ISSN
- 0031-9333 (ISSN-L)
- 1522-1210
- OpenAlex
- W2104161119
- Cited by
- 474
- References
- 0
- Citations by year
- 2025: 2 · 2024: 6 · 2023: 3 · 2022: 6 · 2021: 2 · 2020: 3 · 2019: 6 · 2018: 6 · 2017: 8 · 2016: 11 · 2015: 10 · 2014: 10 · 2013: 6 · 2012: 10
- FWCI
- 7.60
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Physiological Reviews (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bone Metabolism and Diseases
- Health Sciences › Medicine › Orthopedics and Sports Medicine › Bone health and osteoporosis research
- Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Alkaline Phosphatase Research Studies
- Keywords
- bone cells, osteoblasts, osteoclasts, osteocytes, cell proliferation, cell differentiation, hormonal regulation, bone remodeling
- MeSH terms
- Animals, Bone Development, Calcitonin, Calcitriol, Cell Differentiation, Cell Division, Humans, Osteoblasts, Osteoclasts, Osteogenesis, Parathyroid Hormone, Prostaglandins
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
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