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Cited by 348

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Synaptic vesicle biogenesis, docking, and fusion: a molecular description

Calakos, N., Scheller, R. H.·1996·Physiological Reviews

Abstract

Secretion of neurotransmitter is the primary means of intercellular communication within the nervous system. This process is regulated by a highly orchestrated cycle of membrane trafficking within the presynaptic nerve terminal. Characterization of proteins localized to the synaptic vesicle and the subsequent studies of their properties have led to a model for the biochemical pathway that underlies vesicle docking, activation, and fusion. The proteins found to function in the synapse are related to those in yeast and other organisms, demonstrating that the mechanisms that mediate vesicle trafficking are conserved in all eukaryotic species.

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Crossref · 10.1152/physrev.1996.76.1.1

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Metadata

Authors
Calakos, N., & Scheller, R. H.
Venue
Physiological Reviews
Published
1996-01-01
Volume
76
Issue
1
Pages
1-29
ISSN
  • 0031-9333 (ISSN-L)
  • 1522-1210
OpenAlex
W2172586216
Cited by
348
References
0
FWCI
21.08
Type
journal article
Language
en
Open access
closed

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CoChat. (2026). Citation check: Synaptic vesicle biogenesis, docking, and fusion: a molecular description. https://app.cochat.ai/papers/10.1152/physrev.1996.76.1.1
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Calakos, N., & Scheller, R. H. (1996). Synaptic vesicle biogenesis, docking, and fusion: a molecular description. Physiological Reviews. https://doi.org/10.1152/physrev.1996.76.1.1

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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.