Genetic and functional changes in mitochondria associated with aging

Ozawa, T.·1997·Physiological Reviews

Cited by (313)

Items 101–200 of 313

  1. Human skeletal muscle mitochondrial metabolism in youth and senescence: no signs of functional changes in ATP formation and mitochondrial oxidative capacity
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  2. The aging myocardium: roles of mitochondrial damage and lysosomal degradation
    Terman, Alexei, Brunk, Ulf T. · 2005 · Heart, Lung and Circulation
  3. The role of mitochondria in the establishment of oocyte functional competence
    Jennifer Cummins · 2004 · European Journal of Obstetrics & Gynecology and Reproductive Biology
  4. Development of lipophilic cations as therapies for disorders due to mitochondrial dysfunction
    Michael P. Murphy · 2001 · Expert Opinion on Biological Therapy
  5. Αlpha-Synuclein as a Mediator in the Interplay between Aging and Parkinson’s Disease
    Wojciech Bobela, Patrick Aebischer, Bernard Laurent Schneider · 2015 · Biomolecules
  6. Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxia
    Carvalho, Cristina, Correia, Sónia C., Santos, Renato X., Cardoso, Susana, Moreira, Paula I., Clark, Timothy A., Zhu, Xiongwei, Smith, Mark A., Perry, George · 2009 · Journal of Bioenergetics and Biomembranes
  7. Ambient temperature influences aging in an annual fish (Nothobranchius rachovii)
    Chin‐Yuan Hsu, Ya‐Chi Chiu · 2009 · Aging Cell
  8. Neuronal plasticity and stressor toxicity during aging
    Gregory J. Brewer · 2000 · Experimental Gerontology
  9. New developments on the functions of coenzyme Q in mitochondria
    Maria Luisa Genova, Giorgio Lenaz · 2011 · BioFactors
  10. Neuropsychiatric complications of aging with HIV
    Crystal C. Watkins, Glenn J. Treisman · 2012 · Journal of NeuroVirology
  11. Age-associated decreased activities of mitochondrial electron transport chain complexes in heart and skeletal muscle: role of l-carnitine
    Kumaran Sundaram, Marimuthu Subathra, M BALU, Chinnakkannu Panneerselvam · 2004 · Chemico-Biological Interactions
  12. Age-Related Markers Assayed at Different Developmental Stages of the Annual Fish Nothobranchius rachovii
    Chin‐Yuan Hsu, Y.-C. Chiu, W.-L. Hsu, Y.-P. Chan · 2008 · The Journals of Gerontology Series A
  13. Effects of Caloric Restriction on Cardiac Oxidative Stress and Mitochondrial Bioenergetics: Potential Role of Cardiac Sirtuins
    Ken Shinmura · 2013 · Oxidative Medicine and Cellular Longevity
  14. Alzheimer’s Disease Pathologic Cascades: Who Comes First, What Drives What
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  15. Regulation of mitochondrial DNA content and cancer
    Masahiro Higuchi · 2006 · Mitochondrion
  16. Age-Induced Morphological, Biochemical, and Functional Alterations in Isolated Mitochondria From Murine Skeletal Muscle
    Pedro Figueiredo, Rita M. Ferreira, Hans-Joachim Appell, José Alberto Duarte · 2008 · The Journals of Gerontology Series A
  17. Semen levels of mitochondrial DNA deletions in men attending an infertility clinic do not correlate with phenotype
    CUMMINS, Jequier, MARTIN · 1998 · International Journal of Andrology
  18. Autophagy in aging and in neurodegenerative disorders
    Yogendra Singh Rajawat, Ioannis Bossis · 2008 · HORMONES
  19. Dietary Mitophagy Enhancer: A Strategy for Healthy Brain Aging?
    Nimmy Varghese, Selina Werner, Amandine Grimm, Anne Eckert · 2020 · Antioxidants
  20. NADPH oxidase 2-dependent oxidative stress, mitochondrial damage and apoptosis in the ventral cochlear nucleus of d-galactose-induced aging rats
    Zhengde Du, Qianting Yang, L. Liu, S. Li, Jichun Zhao, Jing Hu, Chang Hai Liu, Daolin Qian, Chunsheng Gao · 2014 · Neuroscience
  21. Mitochondrial DNA Damage Patterns and Aging: Revising the Evidences for Humans and Mice
    Nadiya Kazachkova · 2013 · Aging and Disease
  22. Base excision repair of mitochondrial DNA damage in mammalian cells
    Susan P. LeDoux, G. Lee Wilson · 2001 · Progress in nucleic acid research and molecular biology
  23. Ubiquinone. Biosynthesis of quinone ring and its isoprenoid side chain. Intracellular localization.
    Anna Szkopińska · 2000 · Acta Biochimica Polonica
  24. Isolation and microinjection of somatic cell‐derived mitochondria and germline heteroplasmy in transmitochondrial mice
    Michael H. Irwin, Larry W. Johnson, Carl A. Pinkert · 1999 · Transgenic Research
  25. Mitochondria in the life and death of neurons
    Samantha L. Budd, David G. Nicholls · 1998 · Essays in Biochemistry
  26. Aberrant expression of nitric oxide synthase III in Alzheimer’s disease: relevance to cerebral vasculopathy and neurodegeneration
    Suzanne M. de la Monte, B-X Lu, Y. K. Sohn, DANNIE ETIENNE, Joanny Kraft, Neema Ganju, Jack R. Wands · 2000 · Neurobiology of Aging
  27. Catabolic Insufficiency and Aging
    Alexei Terman · 2006 · Annals of the New York Academy of Sciences
  28. A Novel Homoplasmic Mutation in mtDNA with a Single Evolutionary Origin as a Risk Factor for Cardiomyopathy
    Wee Soo Shin, Masashi Tanaka, Jun-ichi Suzuki, Chieko Hemmi, Teruhiko Toyo‐oka · 2000 · The American Journal of Human Genetics
  29. Actions of 17β-estradiol and testosterone in the mitochondria and their implications in aging
    Vasconsuelo, Andrea, Milanesi, Lorena, Boland, Ricardo · 2013 · Ageing Research Reviews
  30. Atrial Fibrillation Is Associated With Accumulation of Aging-Related Common Type Mitochondrial DNA Deletion Mutation in Human Atrial Tissue*
    Ling‐Ping Lai, Chien-Chen Tsai, Ming‐Jai Su · 2003 · CHEST Journal
  31. Nitric oxide-induced damage to mtDNA and its subsequent repair
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  32. DPPH Radical Scavenging Activity of Tricin and Its Conjugates Isolated from “Njavara” Rice Bran: A Density Functional Theory Study
    Manjaly J. Ajitha, Smitha Mohanlal, Cherumuttathu Hariharan Suresh · 2012 · Journal of Agricultural and Food Chemistry
  33. Ganoderma lucidum (Fr.) P. Karst enhances activities of heart mitochondrial enzymes and respiratory chain complexes in the aged rat
    N.P. Sudheesh, Thekkuttuparambil Ananthanarayanan Ajith, Kainoor Krishnankutty Janardhanan · 2009 · Biogerontology
  34. Honeybee trophocytes and fat cells as target cells for cellular senescence studies
    Yu-Shan Hsieh, Chin‐Yuan Hsu · 2010 · Experimental Gerontology
  35. Cardiac ischemia/reperfusion, aging, and redox-dependent alterations in mitochondrial function.
    Hesham A. Sadek, Amy C. Nulton-Persson, Pamela A. Szweda, L. Szweda · 2003 · Archives of Biochemistry and Biophysics
  36. Testosterone Upregulates the Expression of Mitochondrial ND1 and ND4 and Alleviates the Oxidative Damage to the Nigrostriatal Dopaminergic System in Orchiectomized Rats
    Wensheng Yan, Yunxiao Kang, Xiaoming Ji, Shuangcheng Li, Yingkun Li, Guoliang Zhang, Huixian Cui, Geming Shi · 2017 · Oxidative Medicine and Cellular Longevity
  37. Supercomplex organization of the mitochondrial respiratory chain and the role of the Coenzyme Q pool: Pathophysiological implications
    Maria Luisa Genova, Cristina Bianchi, Giorgio Lenaz · 2005 · BioFactors
  38. DNA Recombination-Initiation Plays a Role in the Extremely Biased Inheritance of Yeast [rho−] Mitochondrial DNA That Contains the Replication Origin ori5
    Feng Ling, Akiko Hori, Takehiko Shibata · 2006 · Molecular and Cellular Biology
  39. The increase in mitochondrial DNA copy number in the tissues of gamma-irradiated mice.
    Ludmila V. Malakhova, Vladimir G Bezlepkin, Antipova Vn, Tat'yana Ushakova, Ludmila A. Fomenko, Nikolay P. Sirota, A.I. Gaziev · 2005 · PubMed
  40. The effect of aging and an oxidative stress on peroxide levels and the mitochondrial membrane potential in isolated rat hepatocytes
    Marika Cavazzoni, Silvia Barogi, Alessandra Baracca, Giovanna Parenti Castelli, Giorgio Lenaz · 1999 · FEBS Letters
  41. Male infertility and mitochondrial DNA
    Elena Carra, Donatella Sangiorgi, F Gattuccio · 2004 · Biochemical and Biophysical Research Communications
  42. Cytoplasmic inheritance and its implications for animal biotechnology
    J. M. Cummins · 2001 · Theriogenology
  43. Metabolism and lifespan
    Wayne A. Van Voorhies · 2001 · Experimental Gerontology
  44. Apoptosis-related changes in skeletal muscles of patients with mitochondrial diseases
    Takao Mitsui, Itsuro Endo, Toshio Matsumoto, Yoshifumi Umaki, Masashi Akaike · 2002 · Acta Neuropathologica
  45. Mitochondrial Alterations and Neuropsychiatric Disorders
    Donatella Marazziti, Stefano Baroni, Michela Picchetti, P. Landi, S. Silvestri, Elena Vatteroni, Mario Catena Dell’Osso · 2011 · Current Medicinal Chemistry
  46. Autophagy and aging—importance of amino acid levels
    Wulf Dröge · 2004 · Mechanisms of Ageing and Development
  47. Regulation of Energy Metabolism in Human Cells in Aging and Diabetes: FoF1, mtDNA, UCP, and ROS
    Yasuo Kagawa, Seung Hun Cha, Kyoko Hasegawa, Toshiro Hamamoto, Hitoshi Endo · 1999 · Biochemical and Biophysical Research Communications
  48. Genetic Maternal Effects on HumanLife Span through the Inh eritance of Mitochondrial DNA
    Helena Korpelainen · 1999 · Human Heredity
  49. Reduced Mitochondrial DNA Transcription in Senescent Rat Heart
    Antoni L. Andreu, Maria Antonia Arbos, Acisclo Pérez Martos · 1998 · Biochemical and Biophysical Research Communications
  50. Mitochondrial DNA Mutations and Age
    Takayuki Ozawa · 1998 · Annals of the New York Academy of Sciences
  51. Structurally diverse c-Myc inhibitors share a common mechanism of action involving ATP depletion
    Huabo Wang, Lokendra Sharma, Jie Li Lu, Paul Finch, Steven Fletcher, Edward V. Prochownik · 2015 · Oncotarget
  52. Morphological and biochemical studies on aging and autophagy
    Rita Rezzani, Alessandra Stacchiotti, Luigi Fabrizio Rodella · 2011 · Ageing Research Reviews
  53. Upregulation of Mitochondrial Base-Excision Repair Capability Within Rat Brain After Brief Ischemia
    Dexi Chen, Manabu Minami, David Clifford Henshall, Robert Meller, Glen E. Kisby, Roger Pancoast Simon · 2003 · Journal of Cerebral Blood Flow & Metabolism
  54. Oxygen and life span: chronic hypoxia as a model for studying HIF-1α, VEGF and NOS during aging
    Camillo Di Giulio, Giuseppina Bianchi, Marisa Cacchio, Luciano Artese, Cinzia Rapino, Maria Antonietta Macrì, Carmine Di Ilio · 2005 · Respiratory Physiology & Neurobiology
  55. DNA recombination protein-dependent mechanism of homoplasmy and its proposed functions
    Takehiko Shibata, Feng Ling · 2006 · Mitochondrion
  56. Gene therapy by mitochondrial transfer
    Yasuo Kagawa, Yutaka Inoki, Hitoshi Endo · 2001 · Advanced Drug Delivery Reviews
  57. Respiratory supercomplexes plasticity and implications
    Yidong Bai · 2015 · Frontiers in bioscience
  58. A Current Update on the Use of Alpha Lipoic Acid in the Management of Type 2 Diabetes Mellitus
    Zhongxian Poh, K. Goh · 2009 · Endocrine Metabolic & Immune Disorders - Drug Targets
  59. Respiratory supercomplexes and the functional segmentation of the CoQ pool
    Raquel Moreno‐Loshuertos, José Antonio Enrı́quez · 2016 · Free Radical Biology and Medicine
  60. Ultrastructure of testicular macrophages in aging mice
    Francesco Giannessi, Maria Anita Giambelluca, Maria Concetta Scavuzzo, Riccardo Ruffoli · 2004 · Journal of Morphology
  61. Differentiation and the cytomorphology of salivary gland tumors with specific reference to oncocytic metaplasia
    Irving Dardick, Catalena Birek, Mark William Lingen · 1999 · Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology
  62. Median network analysis of defectively sequenced entire mitochondrial genomes from early and contemporary disease studies
    Hans‐Jürgen Bandelt, Yong‐Gang Yao, Cláudio M. Bravi · 2009 · Journal of Human Genetics
  63. Mitochondrial Genome Mutation in Cell Death and Aging
    Takayuki Ozawa · 1999 · Journal of Bioenergetics and Biomembranes
  64. CONTEMPORARY PERCEPTION OF ANTIOXIDANT SYSTEM OF HUMAN ORGANISM
    Elena Anatolyevna Chanchaeva, Р. И. Айзман, Alexey Dmitrievich Gerasev · 2013 · Экология человека
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  66. Direct measurement of oxygen consumption rate on the nematode Caenorhabditis elegans by using an optical technique
    Hitoshi Suda, Tetsuji Shouyama, Kayo Yasuda, Naoaki Ishii · 2005 · Biochemical and Biophysical Research Communications
  67. Does Mitochondrial DNA Play a Role in Parkinson's Disease? A Review of Cybrid and Other Supportive Evidence
    Russell Howard Swerdlow · 2011 · Antioxidants and Redox Signaling
  68. Effect of DL-α-lipoic acid on the status of lipid peroxidation and antioxidants in mitochondria of aged rats
    Arivazhagan Palaniyappan, Kadirvel Ramanathan, Chinnakkannu Panneerselvam · 2001 · The Journal of Nutritional Biochemistry
  69. A mutation in a mitochondrial ABC transporter results in mitochondrial dysfunction through oxidative damage of mitochondrial DNA
    Hiroshi Senbongi, F. Ling, Takehiko Shibata · 1999 · Molecular and General Genetics MGG
  70. Lipofuscin accumulation and autophagy in glaucomatous human lamina cribrosa cells
    Elizabeth Margaret McElnea, Emily L. Hughes, Alo McGoldrick, Amanda H McCann, Barry Quill, Neil Gerard Docherty, Mustapha Irnaten, Michael Farrell, Abbot F. Clark, Colm J. O'Brien et al. · 2014 · BMC Ophthalmology
  71. Mitochondrial function in fibroblasts with aging in culture and/or Alzheimer's disease
    Hsueh‐Meei Huang, Corinne Fowler, Hui Xu, Hui Zhang, Gary E. Gibson · 2004 · Neurobiology of Aging
  72. Mitochondrial damage in patients with long-term corticosteroid therapy: development of oculoskeletal symptoms similar to mitochondrial disease
    Takao Mitsui, Yoshifumi Umaki, Masakazu Nagasawa, Masashi Akaike, Kenji Aki, Hiroyuki Azuma, Shyuji Ozaki, Masaaki Odomi, Toshio Matsumoto · 2002 · Acta Neuropathologica
  73. Exploring unusual antioxidant activity in a benzoic acid derivative: a proposed mechanism for citrinin
    Elizabeth M. Heider, James K. Harper, David M. Grant, Angela M. Hoffman, Frank M. Dugan, David P. Tomer, Kim Leslie O'Neill · 2005 · Tetrahedron
  74. Detection of mitochondrial DNA mutations in human gingival tissues.
    Naoyuki Sugano, Kazuhiro Kawamoto, Hikaru Numazaki · 2000 · Journal of Oral Science
  75. Protective effects of a catechin-rich extract on the hippocampal formation and spatial memory in aging rats
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  76. Poly(ADP-ribose) polymerase facilitates the repair of N-methylpurines in mitochondrial DNA.
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  77. Reducing Power of Simple Polyphenols by Electron-Transfer Reactions Using a New Stable Radical of the PTM Series, Tris(2,3,5,6-tetrachloro-4-nitrophenyl)methyl Radical
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  78. Mapping mechanisms and charting the time course of premature cell senescence and apoptosis: lysosomal dysfunction and ganglioside accumulation in endothelial cells
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  79. Testosterone alleviates mitochondrial ROS accumulation and mitochondria-mediated apoptosis in the gastric mucosa of orchiectomized rats
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  80. Reversing chemoresistance in cisplatin-resistant human ovarian cancer cells: A role of c-Jun NH2-terminal kinase 1
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  81. Mitochondrial function, mitochondrial DNA and ageing: a reappraisal
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  82. A Density Functional Theory Study on Pelargonidin
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  83. Protective action of green tea catechins in neuronal mitochondria during aging
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  85. No mitochondrial DNA deletions but more D-loop point mutations in repeated pregnancy loss
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  86. Effect of the oxidative stress induced by adriamycin on rat hepatocyte bioenergetics during ageing
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  87. Do we age because we have mitochondria?
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  88. The changes of age-related molecules in the trophocytes and fat cells of queen honeybees (Apis mellifera)
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  90. Autophagy and Heart Failure: A Possible Role for Homocysteine
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  91. Clinical implications of mitochondrial disease
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  93. Human livers with cirrhosis and hepatocellular carcinoma have less mitochondrial DNA deletion than normal human livers
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  100. Laboratory approach to mitochondrial diseases
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