Genetic and functional changes in mitochondria associated with aging
Ozawa, T.·1997·Physiological Reviews
Cited by (313)
Items 101–200 of 313
- Human skeletal muscle mitochondrial metabolism in youth and senescence: no signs of functional changes in ATP formation and mitochondrial oxidative capacityUlla F. Rasmussen, Peter Krustrup, Michael Kjær, Hans Rasmussen · 2003 · Pflügers Archiv - European Journal of Physiology
- The aging myocardium: roles of mitochondrial damage and lysosomal degradationTerman, Alexei, Brunk, Ulf T. · 2005 · Heart, Lung and Circulation
- The role of mitochondria in the establishment of oocyte functional competenceJennifer Cummins · 2004 · European Journal of Obstetrics & Gynecology and Reproductive Biology
- Development of lipophilic cations as therapies for disorders due to mitochondrial dysfunctionMichael P. Murphy · 2001 · Expert Opinion on Biological Therapy
- Αlpha-Synuclein as a Mediator in the Interplay between Aging and Parkinson’s DiseaseWojciech Bobela, Patrick Aebischer, Bernard Laurent Schneider · 2015 · Biomolecules
- Role of mitochondrial-mediated signaling pathways in Alzheimer disease and hypoxiaCarvalho, Cristina, Correia, Sónia C., Santos, Renato X., Cardoso, Susana, Moreira, Paula I., Clark, Timothy A., Zhu, Xiongwei, Smith, Mark A., Perry, George · 2009 · Journal of Bioenergetics and Biomembranes
- Ambient temperature influences aging in an annual fish (Nothobranchius rachovii)Chin‐Yuan Hsu, Ya‐Chi Chiu · 2009 · Aging Cell
- Neuronal plasticity and stressor toxicity during agingGregory J. Brewer · 2000 · Experimental Gerontology
- New developments on the functions of coenzyme Q in mitochondriaMaria Luisa Genova, Giorgio Lenaz · 2011 · BioFactors
- Neuropsychiatric complications of aging with HIVCrystal C. Watkins, Glenn J. Treisman · 2012 · Journal of NeuroVirology
- Age-associated decreased activities of mitochondrial electron transport chain complexes in heart and skeletal muscle: role of l-carnitineKumaran Sundaram, Marimuthu Subathra, M BALU, Chinnakkannu Panneerselvam · 2004 · Chemico-Biological Interactions
- Age-Related Markers Assayed at Different Developmental Stages of the Annual Fish Nothobranchius rachoviiChin‐Yuan Hsu, Y.-C. Chiu, W.-L. Hsu, Y.-P. Chan · 2008 · The Journals of Gerontology Series A
- Effects of Caloric Restriction on Cardiac Oxidative Stress and Mitochondrial Bioenergetics: Potential Role of Cardiac SirtuinsKen Shinmura · 2013 · Oxidative Medicine and Cellular Longevity
- Alzheimer’s Disease Pathologic Cascades: Who Comes First, What Drives WhatRussell Howard Swerdlow · 2011 · Neurotoxicity Research
- Regulation of mitochondrial DNA content and cancerMasahiro Higuchi · 2006 · Mitochondrion
- Age-Induced Morphological, Biochemical, and Functional Alterations in Isolated Mitochondria From Murine Skeletal MusclePedro Figueiredo, Rita M. Ferreira, Hans-Joachim Appell, José Alberto Duarte · 2008 · The Journals of Gerontology Series A
- Semen levels of mitochondrial DNA deletions in men attending an infertility clinic do not correlate with phenotypeCUMMINS, Jequier, MARTIN · 1998 · International Journal of Andrology
- Autophagy in aging and in neurodegenerative disordersYogendra Singh Rajawat, Ioannis Bossis · 2008 · HORMONES
- Dietary Mitophagy Enhancer: A Strategy for Healthy Brain Aging?Nimmy Varghese, Selina Werner, Amandine Grimm, Anne Eckert · 2020 · Antioxidants
- NADPH oxidase 2-dependent oxidative stress, mitochondrial damage and apoptosis in the ventral cochlear nucleus of d-galactose-induced aging ratsZhengde Du, Qianting Yang, L. Liu, S. Li, Jichun Zhao, Jing Hu, Chang Hai Liu, Daolin Qian, Chunsheng Gao · 2014 · Neuroscience
- Mitochondrial DNA Damage Patterns and Aging: Revising the Evidences for Humans and MiceNadiya Kazachkova · 2013 · Aging and Disease
- Base excision repair of mitochondrial DNA damage in mammalian cellsSusan P. LeDoux, G. Lee Wilson · 2001 · Progress in nucleic acid research and molecular biology
- Ubiquinone. Biosynthesis of quinone ring and its isoprenoid side chain. Intracellular localization.Anna Szkopińska · 2000 · Acta Biochimica Polonica
- Isolation and microinjection of somatic cell‐derived mitochondria and germline heteroplasmy in transmitochondrial miceMichael H. Irwin, Larry W. Johnson, Carl A. Pinkert · 1999 · Transgenic Research
- Mitochondria in the life and death of neuronsSamantha L. Budd, David G. Nicholls · 1998 · Essays in Biochemistry
- Aberrant expression of nitric oxide synthase III in Alzheimer’s disease: relevance to cerebral vasculopathy and neurodegenerationSuzanne M. de la Monte, B-X Lu, Y. K. Sohn, DANNIE ETIENNE, Joanny Kraft, Neema Ganju, Jack R. Wands · 2000 · Neurobiology of Aging
- Catabolic Insufficiency and AgingAlexei Terman · 2006 · Annals of the New York Academy of Sciences
- A Novel Homoplasmic Mutation in mtDNA with a Single Evolutionary Origin as a Risk Factor for CardiomyopathyWee Soo Shin, Masashi Tanaka, Jun-ichi Suzuki, Chieko Hemmi, Teruhiko Toyo‐oka · 2000 · The American Journal of Human Genetics
- Actions of 17β-estradiol and testosterone in the mitochondria and their implications in agingVasconsuelo, Andrea, Milanesi, Lorena, Boland, Ricardo · 2013 · Ageing Research Reviews
- Atrial Fibrillation Is Associated With Accumulation of Aging-Related Common Type Mitochondrial DNA Deletion Mutation in Human Atrial Tissue*Ling‐Ping Lai, Chien-Chen Tsai, Ming‐Jai Su · 2003 · CHEST Journal
- Nitric oxide-induced damage to mtDNA and its subsequent repairValentina I. Grishko, Nadiya Druzhyna, Susan P. LeDoux · 1999 · Nucleic Acids Research
- DPPH Radical Scavenging Activity of Tricin and Its Conjugates Isolated from “Njavara” Rice Bran: A Density Functional Theory StudyManjaly J. Ajitha, Smitha Mohanlal, Cherumuttathu Hariharan Suresh · 2012 · Journal of Agricultural and Food Chemistry
- Ganoderma lucidum (Fr.) P. Karst enhances activities of heart mitochondrial enzymes and respiratory chain complexes in the aged ratN.P. Sudheesh, Thekkuttuparambil Ananthanarayanan Ajith, Kainoor Krishnankutty Janardhanan · 2009 · Biogerontology
- Honeybee trophocytes and fat cells as target cells for cellular senescence studiesYu-Shan Hsieh, Chin‐Yuan Hsu · 2010 · Experimental Gerontology
- Cardiac ischemia/reperfusion, aging, and redox-dependent alterations in mitochondrial function.Hesham A. Sadek, Amy C. Nulton-Persson, Pamela A. Szweda, L. Szweda · 2003 · Archives of Biochemistry and Biophysics
- Testosterone Upregulates the Expression of Mitochondrial ND1 and ND4 and Alleviates the Oxidative Damage to the Nigrostriatal Dopaminergic System in Orchiectomized RatsWensheng Yan, Yunxiao Kang, Xiaoming Ji, Shuangcheng Li, Yingkun Li, Guoliang Zhang, Huixian Cui, Geming Shi · 2017 · Oxidative Medicine and Cellular Longevity
- Supercomplex organization of the mitochondrial respiratory chain and the role of the Coenzyme Q pool: Pathophysiological implicationsMaria Luisa Genova, Cristina Bianchi, Giorgio Lenaz · 2005 · BioFactors
- DNA Recombination-Initiation Plays a Role in the Extremely Biased Inheritance of Yeast [rho−] Mitochondrial DNA That Contains the Replication Origin ori5Feng Ling, Akiko Hori, Takehiko Shibata · 2006 · Molecular and Cellular Biology
- The increase in mitochondrial DNA copy number in the tissues of gamma-irradiated mice.Ludmila V. Malakhova, Vladimir G Bezlepkin, Antipova Vn, Tat'yana Ushakova, Ludmila A. Fomenko, Nikolay P. Sirota, A.I. Gaziev · 2005 · PubMed
- The effect of aging and an oxidative stress on peroxide levels and the mitochondrial membrane potential in isolated rat hepatocytesMarika Cavazzoni, Silvia Barogi, Alessandra Baracca, Giovanna Parenti Castelli, Giorgio Lenaz · 1999 · FEBS Letters
- Male infertility and mitochondrial DNAElena Carra, Donatella Sangiorgi, F Gattuccio · 2004 · Biochemical and Biophysical Research Communications
- Cytoplasmic inheritance and its implications for animal biotechnologyJ. M. Cummins · 2001 · Theriogenology
- Metabolism and lifespanWayne A. Van Voorhies · 2001 · Experimental Gerontology
- Apoptosis-related changes in skeletal muscles of patients with mitochondrial diseasesTakao Mitsui, Itsuro Endo, Toshio Matsumoto, Yoshifumi Umaki, Masashi Akaike · 2002 · Acta Neuropathologica
- Mitochondrial Alterations and Neuropsychiatric DisordersDonatella Marazziti, Stefano Baroni, Michela Picchetti, P. Landi, S. Silvestri, Elena Vatteroni, Mario Catena Dell’Osso · 2011 · Current Medicinal Chemistry
- Autophagy and aging—importance of amino acid levelsWulf Dröge · 2004 · Mechanisms of Ageing and Development
- Regulation of Energy Metabolism in Human Cells in Aging and Diabetes: FoF1, mtDNA, UCP, and ROSYasuo Kagawa, Seung Hun Cha, Kyoko Hasegawa, Toshiro Hamamoto, Hitoshi Endo · 1999 · Biochemical and Biophysical Research Communications
- Genetic Maternal Effects on HumanLife Span through the Inh eritance of Mitochondrial DNAHelena Korpelainen · 1999 · Human Heredity
- Reduced Mitochondrial DNA Transcription in Senescent Rat HeartAntoni L. Andreu, Maria Antonia Arbos, Acisclo Pérez Martos · 1998 · Biochemical and Biophysical Research Communications
- Mitochondrial DNA Mutations and AgeTakayuki Ozawa · 1998 · Annals of the New York Academy of Sciences
- Structurally diverse c-Myc inhibitors share a common mechanism of action involving ATP depletionHuabo Wang, Lokendra Sharma, Jie Li Lu, Paul Finch, Steven Fletcher, Edward V. Prochownik · 2015 · Oncotarget
- Morphological and biochemical studies on aging and autophagyRita Rezzani, Alessandra Stacchiotti, Luigi Fabrizio Rodella · 2011 · Ageing Research Reviews
- Upregulation of Mitochondrial Base-Excision Repair Capability Within Rat Brain After Brief IschemiaDexi Chen, Manabu Minami, David Clifford Henshall, Robert Meller, Glen E. Kisby, Roger Pancoast Simon · 2003 · Journal of Cerebral Blood Flow & Metabolism
- Oxygen and life span: chronic hypoxia as a model for studying HIF-1α, VEGF and NOS during agingCamillo Di Giulio, Giuseppina Bianchi, Marisa Cacchio, Luciano Artese, Cinzia Rapino, Maria Antonietta Macrì, Carmine Di Ilio · 2005 · Respiratory Physiology & Neurobiology
- DNA recombination protein-dependent mechanism of homoplasmy and its proposed functionsTakehiko Shibata, Feng Ling · 2006 · Mitochondrion
- Gene therapy by mitochondrial transferYasuo Kagawa, Yutaka Inoki, Hitoshi Endo · 2001 · Advanced Drug Delivery Reviews
- Respiratory supercomplexes plasticity and implicationsYidong Bai · 2015 · Frontiers in bioscience
- A Current Update on the Use of Alpha Lipoic Acid in the Management of Type 2 Diabetes MellitusZhongxian Poh, K. Goh · 2009 · Endocrine Metabolic & Immune Disorders - Drug Targets
- Respiratory supercomplexes and the functional segmentation of the CoQ poolRaquel Moreno‐Loshuertos, José Antonio Enrı́quez · 2016 · Free Radical Biology and Medicine
- Ultrastructure of testicular macrophages in aging miceFrancesco Giannessi, Maria Anita Giambelluca, Maria Concetta Scavuzzo, Riccardo Ruffoli · 2004 · Journal of Morphology
- Differentiation and the cytomorphology of salivary gland tumors with specific reference to oncocytic metaplasiaIrving Dardick, Catalena Birek, Mark William Lingen · 1999 · Oral Surgery Oral Medicine Oral Pathology Oral Radiology and Endodontology
- Median network analysis of defectively sequenced entire mitochondrial genomes from early and contemporary disease studiesHans‐Jürgen Bandelt, Yong‐Gang Yao, Cláudio M. Bravi · 2009 · Journal of Human Genetics
- Mitochondrial Genome Mutation in Cell Death and AgingTakayuki Ozawa · 1999 · Journal of Bioenergetics and Biomembranes
- CONTEMPORARY PERCEPTION OF ANTIOXIDANT SYSTEM OF HUMAN ORGANISMElena Anatolyevna Chanchaeva, Р. И. Айзман, Alexey Dmitrievich Gerasev · 2013 · Экология человека
- Vegetables and Their Bioactive Compounds as Anti-Aging DrugsHamza Mechchate, Aicha El Allam, Nasreddine El Omari, Naoufal El Hachlafi, Mohammad Ali Shariati, Polrat Wilairatana, Mohammad Suleiman Mubarak, Abdelhakim Bouyahya · 2022 · Molecules
- Direct measurement of oxygen consumption rate on the nematode Caenorhabditis elegans by using an optical techniqueHitoshi Suda, Tetsuji Shouyama, Kayo Yasuda, Naoaki Ishii · 2005 · Biochemical and Biophysical Research Communications
- Does Mitochondrial DNA Play a Role in Parkinson's Disease? A Review of Cybrid and Other Supportive EvidenceRussell Howard Swerdlow · 2011 · Antioxidants and Redox Signaling
- Effect of DL-α-lipoic acid on the status of lipid peroxidation and antioxidants in mitochondria of aged ratsArivazhagan Palaniyappan, Kadirvel Ramanathan, Chinnakkannu Panneerselvam · 2001 · The Journal of Nutritional Biochemistry
- A mutation in a mitochondrial ABC transporter results in mitochondrial dysfunction through oxidative damage of mitochondrial DNAHiroshi Senbongi, F. Ling, Takehiko Shibata · 1999 · Molecular and General Genetics MGG
- Lipofuscin accumulation and autophagy in glaucomatous human lamina cribrosa cellsElizabeth Margaret McElnea, Emily L. Hughes, Alo McGoldrick, Amanda H McCann, Barry Quill, Neil Gerard Docherty, Mustapha Irnaten, Michael Farrell, Abbot F. Clark, Colm J. O'Brien et al. · 2014 · BMC Ophthalmology
- Mitochondrial function in fibroblasts with aging in culture and/or Alzheimer's diseaseHsueh‐Meei Huang, Corinne Fowler, Hui Xu, Hui Zhang, Gary E. Gibson · 2004 · Neurobiology of Aging
- Mitochondrial damage in patients with long-term corticosteroid therapy: development of oculoskeletal symptoms similar to mitochondrial diseaseTakao Mitsui, Yoshifumi Umaki, Masakazu Nagasawa, Masashi Akaike, Kenji Aki, Hiroyuki Azuma, Shyuji Ozaki, Masaaki Odomi, Toshio Matsumoto · 2002 · Acta Neuropathologica
- Exploring unusual antioxidant activity in a benzoic acid derivative: a proposed mechanism for citrininElizabeth M. Heider, James K. Harper, David M. Grant, Angela M. Hoffman, Frank M. Dugan, David P. Tomer, Kim Leslie O'Neill · 2005 · Tetrahedron
- Detection of mitochondrial DNA mutations in human gingival tissues.Naoyuki Sugano, Kazuhiro Kawamoto, Hikaru Numazaki · 2000 · Journal of Oral Science
- Protective effects of a catechin-rich extract on the hippocampal formation and spatial memory in aging ratsJorge Rodrigues, Marco Assunção, Nikolay Lukoyanov, Armando Cardoso, Félix Dias Carvalho, José Paulo Andrade · 2013 · Behavioural Brain Research
- Poly(ADP-ribose) polymerase facilitates the repair of N-methylpurines in mitochondrial DNA.Nadiya Druzhyna, Mark E. Smulson, Susan P. LeDoux, G. Lee Wilson · 2000 · Diabetes
- Reducing Power of Simple Polyphenols by Electron-Transfer Reactions Using a New Stable Radical of the PTM Series, Tris(2,3,5,6-tetrachloro-4-nitrophenyl)methyl RadicalJosep Lluı́s Torres, Anna Carreras, Aurora Jiménez, Enric Brillas, X. Torrelles, Jordi Rius, Luís Juliá · 2007 · The Journal of Organic Chemistry
- Mapping mechanisms and charting the time course of premature cell senescence and apoptosis: lysosomal dysfunction and ganglioside accumulation in endothelial cellsSusann A. Patschan, Jun Chen, Olga Gealekman, Katrina Krupincza, Maureen Wang, Liming Shu, James Alan Shayman, Michael S. Goligorsky · 2007 · American Journal of Physiology-Renal Physiology
- Testosterone alleviates mitochondrial ROS accumulation and mitochondria-mediated apoptosis in the gastric mucosa of orchiectomized ratsJie Kang, Zhenhua Jia, Ping Yang · 2018 · Archives of Biochemistry and Biophysics
- Reversing chemoresistance in cisplatin-resistant human ovarian cancer cells: A role of c-Jun NH2-terminal kinase 1Fang Li, Meng Li, Jianfeng Zhou, Hui Xing, Shixuan Wang, Gang Xu, Huaishi Zhu, Beibei Wang, Gang Chen, Yunping Lu et al. · 2005 · Biochemical and Biophysical Research Communications
- Mitochondrial function, mitochondrial DNA and ageing: a reappraisalG. Passarino, G. Rose, D. Bellizzi · 2010 · Biogerontology (Dordrecht)
- A Density Functional Theory Study on PelargonidinLaura Estévez, Ricardo Antonio Mosquera · 2007 · The Journal of Physical Chemistry A
- Protective action of green tea catechins in neuronal mitochondria during agingJosé Paulo Andrade · 2015 · Frontiers in bioscience
- Senescence suppressors: their practical importance in replicative lifespan extension in stem cellsEun Seong Hwang · 2014 · Cellular and Molecular Life Sciences
- No mitochondrial DNA deletions but more D-loop point mutations in repeated pregnancy lossSeyed Mohammad Seyedhassani, Massoud Houshmand, Seyed Mehdi Kalantar · 2010 · Journal of Assisted Reproduction and Genetics
- Effect of the oxidative stress induced by adriamycin on rat hepatocyte bioenergetics during ageingSilvia Barogi, Alessandra Baracca, Marika Cavazzoni, Giovanna Parenti Castelli, Giorgio Lenaz · 2000 · Mechanisms of Ageing and Development
- Do we age because we have mitochondria?Jürgen Bereiter‐Hahn · 2013 · PROTOPLASMA
- The changes of age-related molecules in the trophocytes and fat cells of queen honeybees (Apis mellifera)Yu-Shan Hsieh, Chin‐Yuan Hsu · 2011 · Apidologie
- Angiopoietin-1 Reduces H2O2-Induced Increases in Reactive Oxygen Species and Oxidative Damage to Skin CellsNesreen S. Ismail, Elke A. Pravda, Dan Li, Shou‐Ching Shih, Susan Marie Dallabrida · 2010 · Journal of Investigative Dermatology
- Autophagy and Heart Failure: A Possible Role for HomocysteineThomas Paul Vacek, Jonathan C. Vacek, Neetu Tyagi, Suresh C. Tyagi · 2011 · Cell Biochemistry and Biophysics
- Clinical implications of mitochondrial diseaseStanley Muravchick · 2008 · Advanced Drug Delivery Reviews
- QSAR modeling of antiradical and antioxidant activities of flavonoids using electrotopological state (E-State) atom parametersSupratim Ray, Chandana Sengupta, Kunal Roy · 2007 · Open Chemistry
- Human livers with cirrhosis and hepatocellular carcinoma have less mitochondrial DNA deletion than normal human liversKatsuhiro Kotake, Toshiaki Nonami, Tsuyoshi Kurokawa · 1999 · Life Sciences
- Anesthetic Pitfalls in the Elderly PatientDonald S. Prough · 2005 · Journal of the American College of Surgeons
- Comparative bioenergetic study of neuronal and muscle mitochondria during agingHongzhi Li, Lokendra Kumar Sharma, You-Fen Li, Peiqing Hu, Abimbola Idowu, Danhui Liu, Jianxin Lü, Yidong Bai · 2013 · Free Radical Biology and Medicine
- Effects of L-Malate on Mitochondrial Oxidoreductases in Liver of Aged RatsJin Chuan Wu, Q.-P. WU, Y.-P. PENG, J.-M. ZHANG · 2011 · Physiological Research
- Ultrastructural features of skeletal muscle in adult and aging Ts65Dn mice, a murine model of Down syndrome.Barbara Cisterna, Manuela Costanzo, Elda Scherini, Carlo Zancanaro, Manuela Malatesta · 2013 · Europe PMC (PubMed Central)
- QSAR modeling for lipid peroxidation inhibition potential of flavonoids using topological and structural parametersSupratim Ray, Chandana Sengupta, Kunal Roy · 2008 · Open Chemistry
- Overexpressions of myoglobin and antioxidant enzymes in ragged‐red fibers of skeletal muscle from patients with mitochondrial encephalomyopathyMakoto Kunishige, Takao Mitsui, Masashi Akaike, Masakazu Kawajiri, Masayuki Shono, Hisaomi Kawai, Toshio Matsumoto · 2003 · Muscle & Nerve
- Laboratory approach to mitochondrial diseasesD. Parra, Álvaro González, Carmen Mugueta, A. Martínez, Ignacío Monreal · 2001 · Journal of Physiology and Biochemistry